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    Theophylline and theobromine derivatives
    1.
    发明授权
    Theophylline and theobromine derivatives 失效
    茶碱和可可碱衍生物

    公开(公告)号：US4426383A

    公开(公告)日：1984-01-17

    申请号：US298227

    申请日：1981-08-31

    申请人： Hachiro Sugimoto ,  Takaharu Nakamura ,  Sachiyuki Hamazo ,  Toshiji Igarashi ,  Yoshiharu Daiku

    发明人： Hachiro Sugimoto ,  Takaharu Nakamura ,  Sachiyuki Hamazo ,  Toshiji Igarashi ,  Yoshiharu Daiku

    IPC分类号： C07D473/08 ,  C07D473/10 ,  A61K31/52

    CPC分类号： C07D473/10 ,  C07D473/08 ,  Y10S514/826 ,  Y10S514/929

    摘要： A novel compound has the following formula: ##STR1## in which R.sub.1 and R.sub.2 are methyl or a group having the formula: ##STR2## provided that one of R.sub.1 and R.sub.2 is methyl and the other is said group, wherein R stands for a hydrogen atom or a lower alkyl group, Z stands for a group ##STR3## in which X.sub.1 and X.sub.2, which may be the same or different, stand for a hydrogen atom, a lower alkyl group, a lower alkoxy group, a trifluoromethyl group or a halogen atom, or a pyridyl group or a group ##STR4## in which Y.sub.1 and Y.sub.2, which may be the same or different stand for a hydrogen atom, a lower alkyl group, a lower alkoxy group, a trifluoromethyl group or a halogen atom, X stands for a nitrogen or carbon atom, and n is an integer of from 2 to 10, provided that when R.sub.2 is the group having the formula II, X is not carbon and Z is not pyridyl.

    摘要翻译： 一种新型化合物具有下式：其中R 1和R 2为甲基或具有下式的基团的化合物：其中R1和R2之一为甲基，另一个为所述基团， 其中R代表氢原子或低级烷基，Z代表基团“IMAGE”，其中X1和X2可以相同或不同，代表氢原子，低级烷基，低级烷氧基 ，三氟甲基或卤素原子，或吡啶基或​​其中Y 1和Y 2可以相同或不同，代表氢原子，低级烷基，低级烷氧基，三氟甲基 基团或卤素原子，X表示氮原子或碳原子，n表示2〜10的整数，条件是当R 2为式II的基团时，X不为碳，Z为非吡啶基。

    Theophylline and theobromine derivatives
    2.
    发明授权
    Theophylline and theobromine derivatives 失效
    茶碱和可可碱衍生物

    公开(公告)号：US4564617A

    公开(公告)日：1986-01-14

    申请号：US484044

    申请日：1983-04-11

    申请人： Hachiro Sugimoto ,  Takaharu Nakamura ,  Sachiyuki Hamazo ,  Yoshiharu Daiku

    发明人： Hachiro Sugimoto ,  Takaharu Nakamura ,  Sachiyuki Hamazo ,  Yoshiharu Daiku

    IPC分类号： C07D473/08 ,  C07D473/10 ,  A61K31/52

    CPC分类号： C07D473/10 ,  C07D473/08 ,  Y10S514/826 ,  Y10S514/929

    摘要： A novel compound has the following formula: ##STR1## in which R.sub.1 and R.sub.2 are methyl or a group having the formula: ##STR2## provided that one of R.sub.1 and R.sub.2 is methyl and the other is said group, wherein R stands for a hydrogen atom or a lower alkyl group, Z stands for a group ##STR3## in which X.sub.1 and X.sub.2, which may be the same or different, stand for a hydrogen atom, a lower alkyl group, a lower alkoxy group, a trifluoromethyl group or a halogen atom, or a pyridyl group or a group ##STR4## in which Y.sub.1 and Y.sub.2, which may be the same or different stand for a hydrogen atom, a lower alkyl group, a lower alkoxy group, a trifluoromethyl group or a halogen atom, X stands for a nitrogen or carbon atom, and n is an integer of from 2 to 10, provided that when R.sub.2 is the group having the formula II, X is not carbon and Z is not pyridyl.

    摘要翻译： 一种新型化合物具有下式：其中R 1和R 2为甲基或具有下式的基团的化合物：其中R1和R2之一为甲基，另一个为所述基团， 其中R代表氢原子或低级烷基，Z代表基团“IMAGE”，其中X1和X2可以相同或不同，代表氢原子，低级烷基，低级烷氧基 ，三氟甲基或卤素原子，或吡啶基或​​其中Y 1和Y 2可以相同或不同，代表氢原子，低级烷基，低级烷氧基，三氟甲基 基团或卤素原子，X表示氮原子或碳原子，n表示2〜10的整数，条件是当R 2为式II的基团时，X不为碳，Z为非吡啶基。