-
公开(公告)号：US09671404B2
公开(公告)日：2017-06-06
申请号：US13239011
申请日：2011-09-21
IPC分类号： G01N33/574 , G01N33/50
CPC分类号： G01N33/57419 , G01N33/5047 , G01N33/5743 , G01N33/57438 , G01N33/57446
摘要： The present invention relates to the use of myeloid cell biomarkers for the differential diagnosis, prognosis, and monitoring of renal cell carcinoma (RCC) or colorectal cancer (CRC). The present invention furthermore relates to monitoring the effect of a treatment against renal cell carcinoma (RCC) or colorectal cancer (CRC), and establishing a prognosis of the outcome of the treatment of renal cell carcinoma (RCC) or colorectal cancer (CRC). The present invention furthermore relates to panels of cellular biomarkers for use in the above methods, in particular multicolor panels for measuring said biomarkers.
-
2.发明授权Nucleic acid molecule encoding a bifunctional protein, the protein so encoded uses thereof 失效编码双功能蛋白质的核酸分子，如此编码的蛋白质使用
公开(公告)号：US5955313A
公开(公告)日：1999-09-21
申请号：US842341
申请日：1997-04-24
IPC分类号： G01N33/53 , A61K35/14 , A61K38/00 , A61P35/00 , A61P37/04 , C07K7/06 , C07K14/47 , C12N15/09 , C12Q1/04 , G01N33/566 , G01N33/569 , G01N33/574 , C07H21/04 , C12N15/63
CPC分类号： G01N33/56977 , C07K14/4748 , G01N33/57492 , G01N2333/96466
摘要： The invention involves the identification of an isolated nucleic acid molecule which encodes a tumor rejection antigen. Various uses of this nucleic acid molecule and the protein it encodes are discussed.
摘要翻译： 本发明涉及鉴定编码肿瘤排斥抗原的分离的核酸分子。 讨论了该核酸分子及其编码的蛋白质的各种用途。
-
3.发明授权Nucleic acid molecule encoding a bifunctional protein, the protein so encoded and uses thereof 失效编码双功能蛋白质的核酸分子，如此编码的蛋白质及其用途
公开(公告)号：US5932694A
公开(公告)日：1999-08-03
申请号：US718964
申请日：1996-09-26
IPC分类号： G01N33/53 , A61K35/14 , A61K38/00 , A61P35/00 , A61P37/04 , C07K7/06 , C07K14/47 , C12N15/09 , C12Q1/04 , G01N33/566 , G01N33/569 , G01N33/574 , A61K38/04
CPC分类号： G01N33/56977 , C07K14/4748 , G01N33/57492 , G01N2333/96466
摘要： The invention involves the identification of an isolated nucleic acid molecule which encodes a tumor rejection antigen. Various uses of this nucleic acid molecule and the protein it encodes are discussed.
摘要翻译： 本发明涉及鉴定编码肿瘤排斥抗原的分离的核酸分子。 讨论了该核酸分子及其编码的蛋白质的各种用途。
-
4.发明授权Isolated cytolytic T cells which are specific for complexes OF HLA- B35 molecules and the peptide PHE Pro Ser Asp Ser Trp Cys Tyr PHE, and uses thereof 失效对HLA- B35分子和肽PHE Pro Ser Asp Ser Trp Cys Tyr PHE的复合物特异性的分离的溶细胞T细胞及其用途
公开(公告)号：US5952228A
公开(公告)日：1999-09-14
申请号：US59964
申请日：1998-04-14
IPC分类号： G01N33/53 , A61K35/14 , A61K38/00 , A61P35/00 , A61P37/04 , C07K7/06 , C07K14/47 , C12N15/09 , C12Q1/04 , G01N33/566 , G01N33/569 , G01N33/574 , C12N15/85
CPC分类号： G01N33/56977 , C07K14/4748 , G01N33/57492 , G01N2333/96466
摘要： The invention relates to isolated cytolytic T cells which recognize complexes of HLA-B35 molecules and the peptide defined by SEQ ID NO: 2, as well as methods for identifying HLA-B35 positive cells. The method involves contacting the cytolytic T cells to a sample, and determining activity of these cytolytic T cells.
摘要翻译： 本发明涉及识别HLA-B35分子和由SEQ ID NO：2定义的肽的复合物的分离的溶细胞T细胞以及鉴定HLA-B35阳性细胞的方法。 该方法包括将溶细胞T细胞接触样品，并测定这些溶细胞T细胞的活性。
-
公开(公告)号：US20120225038A1
公开(公告)日：2012-09-06
申请号：US13146823
申请日：2009-01-28
CPC分类号： C12N5/0647 , A61K35/28
摘要： A population of myeloid-derived suppressor cells and the culture procedure to obtain these in vitro starting with bone marrow cells of mice, other animals and human beings, in the presence of specific cytokine combinations used to determine concentrations, is provided.
摘要翻译： 提供了一种骨髓来源的抑制细胞群体，以及在用于确定浓度的特异性细胞因子组合存在下从小鼠，其他动物和人的骨髓细胞开始体外获得这些细胞的培养方法。
-
-
-
-
搜索结果
5 条记录 (耗时 0.019 秒)
