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    Anti-biofilm carbonate compounds for use in oral care compositions
    5.
    发明授权
    Anti-biofilm carbonate compounds for use in oral care compositions 有权
    用于口腔护理组合物的抗生物膜碳酸盐化合物

    公开(公告)号：US08617523B2

    公开(公告)日：2013-12-31

    申请号：US13260920

    申请日：2009-04-01

    申请人： Harsh M. Trivedi ,  Tao Xu ,  Davide Miksa

    发明人： Harsh M. Trivedi ,  Tao Xu ,  Davide Miksa

    IPC分类号： A61K8/00

    CPC分类号： A61K31/265 ,  A61K8/37 ,  A61Q11/00

    摘要： The present invention includes oral care compositions and methods for inhibiting growth and formation of oral biofilms by quorum sensing inhibition and/or bactericidal activity. In some embodiments, the present invention discloses an oral care composition including a therapeutically effective amount of at least one carbonate compound of Formula (1) and at least one excipient: wherein, R1 and R2 are independently: an aliphatic radical; a hydroxyaliphatic radical; or an aryl radical. In some embodiments, the present invention discloses a method of providing oral care benefits including applying to an oral cavity an oral care composition containing a therapeutically effective amount of at least one carbonate compound of Formula (1) and at least one excipient. In some embodiments, the present invention discloses a method of up-regulating or down-regulating periodontal disease metabolites including applying to an oral cavity an oral care composition containing a therapeutically effective amount of at least on carbonate compound of Formula (1) and at least one excipient.

    摘要翻译： 本发明包括口腔护理组合物和通过群体感测抑制和/或杀菌活性抑制口腔生物膜生长和形成的方法。 在一些实施方案中，本发明公开了一种口腔护理组合物，其包含治疗有效量的至少一种式（1）的碳酸酯化合物和至少一种赋形剂：其中，R 1和R 2独立地为：脂族基团; 羟基脂肪族基团; 或芳基。 在一些实施方案中，本发明公开了一种提供口腔护理益处的方法，包括向口腔施用含有治疗有效量的至少一种式（1）的碳酸酯化合物和至少一种赋形剂的口腔护理组合物。 在一些实施方案中，本发明公开了一种上调或降低牙周病代谢物的方法，包括向口腔施用含有治疗有效量的至少一种式（1）的碳酸酯化合物的口腔护理组合物，并且至少 一种赋形剂

    ANTI-BIOFILM CARBONATE COMPOUNDS FOR USE IN ORAL CARE COMPOSITIONS
    6.
    发明申请
    ANTI-BIOFILM CARBONATE COMPOUNDS FOR USE IN ORAL CARE COMPOSITIONS 有权
    用于口腔护理组合物的抗生物素碳酸酯化合物

    公开(公告)号：US20120020896A1

    公开(公告)日：2012-01-26

    申请号：US13260920

    申请日：2009-04-01

    申请人： Harsh M. Trivedi ,  Davide Miksa ,  Tao Xu

    发明人： Harsh M. Trivedi ,  Davide Miksa ,  Tao Xu

    IPC分类号： A61K8/37 ,  A61Q11/00

    CPC分类号： A61K31/265 ,  A61K8/37 ,  A61Q11/00

    摘要： The present invention includes oral care compositions and methods for inhibiting growth and formation of oral biofilms by quorum sensing inhibition and/or bactericidal activity. In some embodiments, the present invention discloses an oral care composition including a therapeutically effective amount of at least one carbonate compound of Formula (1) and at least one excipient: wherein, R1 and R2 are independently: an aliphatic radical; a hydroxyaliphatic radical; or an aryl radical. In some embodiments, the present invention discloses a method of providing oral care benefits including applying to an oral cavity an oral care composition containing a therapeutically effective amount of at least one carbonate compound of Formula (1) and at least one excipient. In some embodiments, the present invention discloses a method of up-regulating or down-regulating periodontal disease metabolites including applying to an oral cavity an oral care composition containing a therapeutically effective amount of at least on carbonate compound of Formula (1) and at least one excipient.

    摘要翻译： 本发明包括口腔护理组合物和通过群体感测抑制和/或杀菌活性抑制口腔生物膜生长和形成的方法。 在一些实施方案中，本发明公开了一种口腔护理组合物，其包含治疗有效量的至少一种式（1）的碳酸酯化合物和至少一种赋形剂：其中，R 1和R 2独立地为：脂族基团; 羟基脂肪族基团; 或芳基。 在一些实施方案中，本发明公开了一种提供口腔护理益处的方法，包括向口腔施用含有治疗有效量的至少一种式（1）的碳酸酯化合物和至少一种赋形剂的口腔护理组合物。 在一些实施方案中，本发明公开了一种上调或降低牙周病代谢物的方法，包括向口腔施用含有治疗有效量的至少一种式（1）的碳酸酯化合物的口腔护理组合物，并且至少 一种赋形剂

    Oregano oral care compositions and methods of use thereof
    9.
    发明授权
    Oregano oral care compositions and methods of use thereof 有权
    牛至口腔护理组合物及其使用方法

    公开(公告)号：US08119169B2

    公开(公告)日：2012-02-21

    申请号：US11256788

    申请日：2005-10-24

    申请人： Cortney L. Worrell ,  Harsh M. Trivedi ,  Kimberlee Panaligan ,  Tao Xu

    发明人： Cortney L. Worrell ,  Harsh M. Trivedi ,  Kimberlee Panaligan ,  Tao Xu

    IPC分类号： A01N65/00

    CPC分类号： A61K8/97 ,  A61Q11/00

    摘要： A multi-benefit oral composition is provided. The oral composition is efficacious as an antibacterial, antiplaque, anti-inflammatory, anti-oxidant, and anti-halitosis oral composition. The active ingredient has one or more active compounds from an extract of oregano. The oral composition can be in the form of a mouth rinse; a dentifrice, including toothpaste, gels, powders; animal products; a film; or confectionaries, such as lozenges, and the like. Methods of making and using the oral composition are also provided.

    摘要翻译： 提供多种益处口服组合物。 口服组合物作为抗菌，抗菌，抗炎，抗氧化和抗口臭组合物是有效的。 活性成分具有来自牛至提取物的一种或多种活性化合物。 口服组合物可以是口腔冲洗的形式; 洁齿剂，包括牙膏，凝胶，粉末; 动物产品; 一个电影; 或糖果，如锭剂等。 还提供了制备和使用口腔组合物的方法。

    OREGANO ORAL CARE COMPOSITIONS AND METHODS OF USE THEREOF
    10.
    发明申请
    OREGANO ORAL CARE COMPOSITIONS AND METHODS OF USE THEREOF 失效
    OREGANO口腔护理组合物及其使用方法

    公开(公告)号：US20120107251A1

    公开(公告)日：2012-05-03

    申请号：US13349595

    申请日：2012-01-13

    申请人： Cortney L. Worrell ,  Harsh M. Trivedi ,  Kimberlee Panaligan ,  Tao Xu

    发明人： Cortney L. Worrell ,  Harsh M. Trivedi ,  Kimberlee Panaligan ,  Tao Xu

    IPC分类号： A61K8/37 ,  A61P29/00 ,  A61K33/30 ,  A61K8/81 ,  A61K31/235 ,  A61Q11/00 ,  A61P1/02

    CPC分类号： A61K8/97 ,  A61Q11/00

    摘要： A multi-benefit oral composition is provided. The oral composition is efficacious as an antibacterial, antiplaque, anti-inflammatory, anti-oxidant, and anti-halitosis oral composition. The active ingredient has one or more active compounds from an extract of oregano. The oral composition can be in the form of a mouth rinse; a dentifrice, including toothpaste, gels, powders; animal products; a film; or confectionaries, such as lozenges, and the like. Methods of making and using the oral composition are also provided.

    摘要翻译： 提供多种益处口服组合物。 口服组合物作为抗菌，抗菌，抗炎，抗氧化和抗口臭组合物是有效的。 活性成分具有来自牛至提取物的一种或多种活性化合物。 口服组合物可以是口腔冲洗的形式; 洁齿剂，包括牙膏，凝胶，粉末; 动物产品; 一个电影; 或糖果，如锭剂等。 还提供了制备和使用口腔组合物的方法。