公开(公告)号：US4435362A

公开(公告)日：1984-03-06

申请号：US441062

申请日：1982-11-12

申请人： Harumi Katsuyama ,  Masaaki Terashima

发明人： Harumi Katsuyama ,  Masaaki Terashima

IPC分类号： G01N33/52 ,  G01N33/68 ,  G01N21/78

CPC分类号： G01N33/526 ,  G01N33/6833

摘要： An improved integral multilayer analytical element for the assay of total protein contained in liquid sample. The element comprises a transparent support on which a reagent layer and a spreading layer are superposed. The feature of the element exists in the reagent layer comprising potassium sodium tartarate, a cupric salt, a basic compound providing a pH in excess of about 12.0 in the element under conditions of use thereof, an alkali-proof polymer and an alkali metal ion complexing agent.

摘要翻译： 改进的整体多层分析元素，用于测定液体样品中所含的总蛋白质。 该元件包括其上叠加有试剂层和扩散层的透明载体。 该元件的特征存在于包含钾酒石酸钠，铜盐，在使用条件下元素中超过约12.0的pH的碱性化合物的试剂层，耐碱聚合物和碱金属离子络合 代理商

公开(公告)号：US4842712A

公开(公告)日：1989-06-27

申请号：US9470

申请日：1987-02-02

申请人： Osamu Seshimoto ,  Masaaki Terashima ,  Yoshio Saito

发明人： Osamu Seshimoto ,  Masaaki Terashima ,  Yoshio Saito

IPC分类号： G01N27/30 ,  G01N27/333

CPC分类号： G01N27/3335 ,  G01N27/307

摘要： In a device for measuring ion activity in a liquid sample such as a body fluid comprising at least one pair of ion-selective electrodes selectively responsive to a specific ion, a porous liquid distributing member for feeding a liquid sample to one electrode of the pair of electrodes, a porous liquid distributing member for feeding a reference liquid to another electrode of the pair of electrodes and a porous bridge for electrically connecting both liquids to each other, the improvement wherein the liquid distributing members are made of a nonwoven fabric composed of cellulosic long fibers.

摘要翻译： 在用于测量诸如体液的液体样品中的离子活性的装置中，所述液体样品包括选择性地响应于特定离子的至少一对离子选择性电极，用于将液体样品供给到所述一对电极中的一个电极的多孔液体分配构件 电极，用于将参考液体供给到该对电极中的另一个电极的多孔液体分配部件和用于将两个液体彼此电连接的多孔桥，其中液体分配部件由纤维素长的无纺布制成 纤维。

公开(公告)号：US07115195B2

公开(公告)日：2006-10-03

申请号：US10856650

申请日：2004-05-27

申请人： Masaaki Terashima ,  Osamu Seshimoto

发明人： Masaaki Terashima ,  Osamu Seshimoto

IPC分类号： G01N27/333

CPC分类号： G01N27/307 ,  Y10T29/49002

摘要： An ion selective monoelectrode complex which is favorably employable to manufacture an ion activity measuring apparatus, has on a common non-electroconductive support sheet, plural ion selective monoelectrodes each of which is composed of an electrode composite consisting of, in order, a silver metal layer, a silver halide layer, an electrolytic material layer, and an ion selective membrane, and an electroconductive terminal which is electrically connected to the silver metal layer and which has an exposed surface, under the condition that the ion selective monoelectrodes are aligned, without electric contact with each other, along an imaginary line bridging the electrode composite and the electroconductive terminal.

摘要翻译： 有利地用于制造离子活性测量装置的离子选择性单电极配合物在普通的非导电性支持片上具有多个离子选择性单电极，它们由依次由银金属层 ，卤化银层，电解质层和离子选择性膜，以及在离子选择性单电极排列的情况下，电连接到银金属层并且具有暴露表面的导电端子，没有电 沿着桥接电极复合体和导电端子的假想线彼此接触。

公开(公告)号：US4865698A

公开(公告)日：1989-09-12

申请号：US26920

申请日：1987-03-17

申请人： Masaaki Terashima

发明人： Masaaki Terashima

IPC分类号： G01N27/416 ,  G01N33/84 ,  G01N33/96

CPC分类号： G01N27/4165 ,  G01N33/96 ,  G01N33/84

摘要： A reference solution for measuring an ionic activity which is utilized at the time of measuring the activity of a particular ion in an aqueous solution by the differential method using ion-selective electrodes, which is characterized by containing the compound having the general formula (I), (II) or (III) and an electrolyte. ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 represent hydrogen atom or a lower alkyl group, respectively, and at least, one or R.sub.3 and R.sub.4 is a lower alkyl group, and X represents chlorine atom or bromine atom, ##STR2## wherein R.sub.5 represents hydrogen atom or a lower alkyl group and A represents a hydrogen atom or a halogen atom, and ##STR3## wherein R.sub.6 represents a hydrogne atom or a lower alkyl group. The reference solution of the invention may be preserved for a long period at room temperature without putrifaction, and the compound (I), (II) or (III) in the reference solution does not or scarcely influence upon the potential difference generated in the ion-selective electrode.

摘要翻译： 用于测量在通过使用离子选择性电极的差示方法测量水溶液中的特定离子的活性时所使用的离子活性的参考溶液，其特征在于含有通式（I）的化合物， ，（II）或（III）和电解质。 （I）其中R1，R2，R3和R4分别表示氢原子或低级烷基，并且至少一个或R3和R4是低级烷基，X表示氯原子或溴原子， 其中R 5表示氢原子或低级烷基，A表示氢原子或卤素原子，且其中R 6表示氢原子或低级烷基。 本发明的参考溶液可以在室温下长时间保存而不会发生脱色，并且参比溶液中的化合物（I），（II）或（III）不会或几乎不影响离子中产生的电势差 选择电极

公开(公告)号：US06869512B2

公开(公告)日：2005-03-22

申请号：US10006169

申请日：2001-12-06

申请人： Masaaki Terashima ,  Osamu Seshimoto

发明人： Masaaki Terashima ,  Osamu Seshimoto

IPC分类号： G01N27/333 ,  G01N27/30 ,  G01N27/416

CPC分类号： G01N27/307

摘要： A device for measuring ionic activity is composed of: a block of insulating material having a hollow space therein, a solution-receiving surface area in which a pair of openings for receiving a sample solution and a reference solution separately are provided, a plurality of solution-supplying surface areas in each of which a pair of openings for supplying outside the sample solution and the reference solution separately are provided; a bridge member fixed on the solution-receiving surface area; a guide member placed in the hollow space which assists to transmit separately the sample solution and the reference member in the hollow space; and two or more ion selective electrodes each of which is placed on each solution-supplying surface area.

摘要翻译： 用于测量离子活性的装置包括：其中具有中空空间的绝缘材料块，设置有用于分别接收样品溶液的一对开口和参考溶液的溶液接收表面区域，多个溶液 提供各自的表面区域，其中分别提供用于在样品溶液和参考溶液外部供应的一对开口;固定在溶液接收表面区域上的桥接构件;设置在中空空间中的辅助传输的引导构件 分别在中空空间中的样品溶液和参考构件; 和两个或更多个离子选择性电极，每个离子选择性电极被放置在每个溶液供应表面区域上。

公开(公告)号：US06767578B2

公开(公告)日：2004-07-27

申请号：US09981528

申请日：2001-10-17

申请人： Masaaki Terashima ,  Osamu Seshimoto

发明人： Masaaki Terashima ,  Osamu Seshimoto

IPC分类号： B05D512

CPC分类号： G01N27/307 ,  Y10T29/49002

摘要： An ion selective monoelectrode complex which is favorably employable to manufacture an ion activity measuring apparatus, has on a common non-electroconductive support sheet, plural ion selective monoelectrodes each of which is composed of an electrode composite consisting of, in order, a silver metal layer, a silver halide layer, an electrolytic material layer, and an ion selective membrane, and an electroconductive terminal which is electrically connected to the silver metal layer and which has an exposed surface, under the condition that the ion selective monoelectrodes are aligned, without electric contact with each other, along an imaginary line bridging the electrode composite and the electroconductive terminal.

摘要翻译： 有利地用于制造离子活性测量装置的离子选择性单电极配合物在普通的非导电性支持片上具有多个离子选择性单电极，每个离子选择性单电极由依次由银金属层 ，卤化银层，电解质层和离子选择性膜，以及在离子选择性单电极排列的情况下，电连接到银金属层并且具有暴露表面的导电端子，没有电 沿着桥接电极复合体和导电端子的假想线彼此接触。

公开(公告)号：US06638404B2

公开(公告)日：2003-10-28

申请号：US09911290

申请日：2001-07-23

申请人： Masaaki Terashima ,  Osamu Seshimoto

发明人： Masaaki Terashima ,  Osamu Seshimoto

IPC分类号： G01N27333

CPC分类号： G01N27/333 ,  G01N27/307

摘要： In the manufacture of an ion selective electrode composed of a non-electroconductive support, a pair of electrodes each of which has a silver metal layer and a silver halide layer, an electrolytic material layer, an ion selective membrane, and a non-electroconductive sheet having a pair of openings for receiving a sample solution and a reference solution, respectively, and having thereon a bridge member for electrically connecting the sample solution received in one opening and the reference solution received in another opening, the ion selective membrane is advantageously divided into two separate portions, one of which is placed in a position above one electrode and another of which is placed in a position above another electrode.

公开(公告)号：US5510082A

公开(公告)日：1996-04-23

申请号：US324987

申请日：1994-10-18

申请人： Kenji Arai ,  Masaaki Terashima ,  Yoshiyuki Doi

发明人： Kenji Arai ,  Masaaki Terashima ,  Yoshiyuki Doi

IPC分类号： G01N35/00 ,  G01N37/00

CPC分类号： G01N35/00029 ,  G01N2035/00049 ,  G01N2035/00089 ,  G01N2035/00455 ,  Y10T436/11 ,  Y10T436/112499 ,  Y10T436/115831

摘要： A plurality of dry chemical analysis films are stacked in a cartridge. A chemical analysis film supplier has a cartridge storage chamber in which a plurality of cartridges are stored so that the chemical analysis films in each cartridge can be taken out by a chemical analysis film removing device. In the the cartridge storage chamber, the cartridges are arranged in a circle, and a moisture-absorber holding portion is formed inside the circle of the cartridges, and a moisture absorber is loaded in the moisture-absorber holding portion.

摘要翻译： 多个干化学分析膜堆叠在盒中。 一种化学分析胶片供应商具有一个盒存储室，其中存储有多个盒，使得每个盒中的化学分析膜可以通过化学分析膜去除装置取出。 在墨盒储存室中，墨盒被布置成圆形，并且在墨盒的圆圈内形成吸湿剂保持部分，并且吸湿剂装载在吸湿剂保持部分中。

公开(公告)号：US07276145B2

公开(公告)日：2007-10-02

申请号：US10621400

申请日：2003-07-18

申请人： Masaaki Terashima ,  Osamu Seshimoto

发明人： Masaaki Terashima ,  Osamu Seshimoto

IPC分类号： G01N27/333

CPC分类号： G01N27/3335 ,  G01N27/4165

摘要： An object of the present invention is to suppress an electric potential drift as described above and improve pH measurement precision in order to obtain practical measurement precision in the dry-type multilayered film-type pH electrode. The present invention provides a complex pH electrode which has at least two ion-selective electrodes comprising a non-conductive support, a pair of electrode layers, an electrolytic layer and an ion-selective membrane where at least one of the ion-selective electrode is a hydrogen ion-selective electrode, wherein the hydrogen ion-selective membrane is saturated with carbon dioxide gas.

摘要翻译： 本发明的目的是为了在干式多层膜型pH电极中获得实用的测量精度，抑制如上所述的电位漂移并改善pH测量精度。 本发明提供一种复合pH电极，其具有至少两个离子选择性电极，其包含非导电支持体，一对电极层，电解质层和离子选择性膜，其中至少一个离子选择性电极为 氢离子选择性电极，其中氢离子选择性膜用二氧化碳气体饱和。

公开(公告)号：US5547874A

公开(公告)日：1996-08-20

申请号：US417270

申请日：1995-04-05

申请人： Masaaki Terashima

发明人： Masaaki Terashima

IPC分类号： G01N33/52 ,  G01N33/66 ,  G01N33/96 ,  G01N31/00 ,  G01N21/77

CPC分类号： G01N33/96 ,  G01N33/526 ,  G01N2496/10 ,  G01N2496/25 ,  G01N2496/30 ,  G01N33/66 ,  Y10S516/922 ,  Y10S516/923 ,  Y10T436/104165 ,  Y10T436/106664 ,  Y10T436/108331

摘要： An aqueous dispersion used for control or calibration of a dry analysis element comprising at least one color producing reagent and a porous layer, which comprises water-insoluble liquid particles having a mean particle size of from about 0.01 to about 10 .mu.m selected from the group consisting of phthalates, trimellitates, phosphates, benzoates, amides, phenols, aliphatic esters, hydrocarbons, halogenated hydrocarbons, adipates, sebacates and natural polymers dispersed therein and a substance which is the same as or similar to the analyte to be determined wherein said substance is selected from the group consisting of glucose, urea, uric acid, creatinine, bilirubin, hemoglobin, triolein, glycerine, cholesterol, triglyceride, (NH.sub.4).sub.2 SO.sub.4, NH.sub.4 Cl, CaCl.sub.2, Ca(NO.sub.3).sub.2, MgCl.sub.2, NaCl, KCl, K.sub.2 HPO.sub.4, (NH.sub.4).sub.2 SO.sub.4, Ca(NO.sub.3).sub.2, and NaNO.sub.3.

摘要翻译： 用于控制或校准干分析元件的水性分散体，其包含至少一种产色试剂和多孔层，其包含平均粒度为约0.01至约10μm的水不溶性液体颗粒，所述水不溶性液体颗粒选自组 由邻苯二甲酸酯，偏苯三酸酯，磷酸酯，苯甲酸酯，酰胺，酚，脂肪族酯，烃，卤代烃，己二酸酯，癸二酸酯和分散在其中的天然聚合物组成，以及与待测分析物相同或类似的物质，其中所述物质为 选自葡萄糖，尿素，尿酸，肌酸酐，胆红素，血红蛋白，三油酸甘油酯，甘油，胆固醇，甘油三酯，（NH4）2SO4，NH4Cl，CaCl2，Ca（NO3）2，MgCl2，NaCl，KCl，K2HPO4， （NH4）2SO4，Ca（NO3）2和NaNO3。