公开(公告)号：US20100317112A1

公开(公告)日：2010-12-16

申请号：US12597895

申请日：2007-04-27

申请人： Hyunjin Yang ,  Heeyoung Lee ,  Jun Seok Lee

发明人： Hyunjin Yang ,  Heeyoung Lee ,  Jun Seok Lee

IPC分类号： C12N5/02

CPC分类号： C12N5/0075 ,  C12N2533/10 ,  C12N2533/40

摘要： The present invention relates to microtype scaffolds for cell culture, which have their specific gravity increased and a method for manufacturing thereof, and more specifically, relates to microtype scaffolds for cell culture, which have their specific gravity increased, by adding a chemically stable inorganic compound having a high specific gravity in manufacturing biocompatible polymer microtype scaffolds for cell culture and a method for manufacturing thereof. In case where the inventive microtype scaffolds for cell culture is used, it is easy to separate cells cultured on microtype scaffolds, and cell damage can be minimized by reducing separation time, and it is easy to recover cells due to a definite boundary layer.

摘要翻译： 本发明涉及具有比重增加的细胞培养用微型支架及其制造方法，更具体地，涉及通过添加化学稳定的无机化合物而使其比重增加的细胞培养用微型支架 在生产用于细胞培养的生物相容性聚合物微型支架中具有高比重及其制造方法。 在使用本发明的用于细胞培养的微型支架的情况下，容易分离在微型支架上培养的细胞，并且通过减少分离时间可以最小化细胞损伤，并且由于确定的边界层容易回收细胞。

公开(公告)号：US20100178681A1

公开(公告)日：2010-07-15

申请号：US12601518

申请日：2008-03-24

申请人： Heeyoung Lee ,  Hyunjin Yang ,  Jun Seok Lee ,  Ji Suk Choi

发明人： Heeyoung Lee ,  Hyunjin Yang ,  Jun Seok Lee ,  Ji Suk Choi

IPC分类号： C12N13/00 ,  C12N5/00

CPC分类号： A61L27/3604 ,  A61L27/3683 ,  A61L2430/40

摘要： The present invention relates to lipid removed scaffolds(lipid-free scaffolds) for human tissue volume replacement or cell culture. More particularly, the present invention relates to a method for preparing lipid removed scaffolds(lipid-free scaffolds) for human tissue volume replacement or cell culture, the method comprising the steps of: fragmenting fat tissue to isolate lipids by ultrasonic treatment or high pressure nozzle spray; removing the isolated lipids and fat tissue from which lipids were not isolated to sterilize. According to the present invention, lipids are removed from fat tissue only by physical treatment to maintain the volume thereof and microstructures such as cellular membrane as much as possible and thus the inventive scaffolds are useful for human tissue volume replacement.

摘要翻译： 本发明涉及用于人组织体积替换或细胞培养的脂质移除的支架（无脂质支架）。 更具体地说，本发明涉及一种用于制备用于人体组织体积置换或细胞培养的脂质去除的支架（无脂质支架）的方法，所述方法包括以下步骤：通过超声处理或高压喷嘴使脂肪组织分离以分离脂质 喷雾; 去除未分离脂质的分离的脂质和脂肪组织进行灭菌。 根据本发明，仅通过物理处理从脂肪组织中除去脂质以尽可能多地维持其体积和微细结构如细胞膜，因此本发明的支架可用于人体组织体积替换。

公开(公告)号：US10549010B2

公开(公告)日：2020-02-04

申请号：US12601518

申请日：2008-03-24

申请人： Heeyoung Lee ,  Hyunjin Yang ,  Jun Seok Lee ,  Ji Suk Choi

发明人： Heeyoung Lee ,  Hyunjin Yang ,  Jun Seok Lee ,  Ji Suk Choi

IPC分类号： A61L27/36

摘要： The present invention relates to lipid removed scaffolds(lipid-free scaffolds) for human tissue volume replacement or cell culture. More particularly, the present invention relates to a method for preparing lipid removed scaffolds(lipid-free scaffolds) for human tissue volume replacement or cell culture, the method comprising the steps of: fragmenting fat tissue to isolate lipids by ultrasonic treatment or high pressure nozzle spray; removing the isolated lipids and fat tissue from which lipids were not isolated to sterilize. According to the present invention, lipids are removed from fat tissue only by physical treatment to maintain the volume thereof and microstructures such as cellular membrane as much as possible and thus the inventive scaffolds are useful for human tissue volume replacement.

公开(公告)号：US08066202B2

公开(公告)日：2011-11-29

申请号：US12528442

申请日：2008-02-21

申请人： Heeyoung Lee

发明人： Heeyoung Lee

IPC分类号： B05B9/04

CPC分类号： B65D83/0066 ,  B05B11/047 ,  B05B11/048

摘要： Disclosed therein is a fluid jetting apparatus. The fluid jetting apparatus includes: a nozzle having a jetting hole adapted to jet a fluid; a nozzle opening and closing part adapted to open and close the jetting hole; at least one elastic fluid-storing part adapted to store the fluid therein and connected with the nozzle at a portion thereof in such a way as to jet the fluid by its elasticity through the jetting hole, the elastic fluid-storing part increasing elasticity accumulated by receiving the external force; and a pressurizing part adapted to increase elasticity accumulated in the elastic fluid-storing part by applying the force to the elastic fluid-storing part. The fluid jetting apparatus is applied to various devices, such as a sprayer, an atomizer, an oral cleaner, and so on, for jetting materials of a liquid, gas or gel type to thereby jet the fluid with a strong jetting force in a convenient manipulation.

摘要翻译： 其中公开了一种流体喷射装置。 流体喷射装置包括：具有适于喷射流体的喷射孔的喷嘴; 喷嘴开闭部，其适于打开和关闭所述喷射孔; 至少一个弹性流体存储部件，其适于将流体存储在其中并以其一部分与喷嘴连接，以便通过其喷射孔的弹性来喷射流体，弹性流体储存部分增加由 接受外力; 以及加压部，其适于通过向所述弹性流体存储部施加力来增加在所述弹性流体储存部中累积的弹性。 流体喷射装置用于喷射器，雾化器，口腔清洁器等各种装置，用于喷射液体，气体或凝胶类型的材料，从而以强烈的喷射力方便地喷射流体，方便 操纵。

公开(公告)号：US20100252657A1

公开(公告)日：2010-10-07

申请号：US12528442

申请日：2008-02-21

申请人： Heeyoung Lee

发明人： Heeyoung Lee

IPC分类号： B05B9/04

CPC分类号： B65D83/0066 ,  B05B11/047 ,  B05B11/048

摘要： Disclosed therein is a fluid jetting apparatus. The fluid jetting apparatus includes: a nozzle having a jetting hole adapted to jet a fluid; a nozzle opening and closing part adapted to open and close the jetting hole; at least one elastic fluid-storing part adapted to store the fluid therein and connected with the nozzle at a portion thereof in such a way as to jet the fluid by its elasticity through the jetting hole, the elastic fluid-storing part increasing elasticity accumulated by receiving the external force; and a pressurizing part adapted to increase elasticity accumulated in the elastic fluid-storing part by applying the force to the elastic fluid-storing part. The fluid jetting apparatus is applied to various devices, such as a sprayer, an atomizer, an oral cleaner, and so on, for jetting materials of a liquid, gas or gel type to thereby jet the fluid with a strong jetting force in a convenient manipulation.

摘要翻译： 其中公开了一种流体喷射装置。 流体喷射装置包括：具有适于喷射流体的喷射孔的喷嘴; 喷嘴开闭部，其适于打开和关闭所述喷射孔; 至少一个弹性流体存储部件，其适于将流体存储在其中并以其一部分与喷嘴连接，以便通过其喷射孔的弹性来喷射流体，弹性流体储存部分增加由 接受外力; 以及加压部，其适于通过向所述弹性流体存储部施加力来增加在所述弹性流体储存部中累积的弹性。 流体喷射装置用于喷射器，雾化器，口腔清洁器等各种装置，用于喷射液体，气体或凝胶类型的材料，从而以强烈的喷射力方便地喷射流体，方便 操纵。

公开(公告)号：US20130096609A1

公开(公告)日：2013-04-18

申请号：US13807003

申请日：2011-06-20

申请人： Heeyoung Lee ,  Hyunjin Yang

发明人： Heeyoung Lee ,  Hyunjin Yang

IPC分类号： A61B17/06

CPC分类号： A61B17/06066 ,  A61B17/06 ,  A61B2017/00792 ,  A61B2017/0477 ,  A61B2017/06052 ,  A61B2017/06176 ,  Y10T29/49826

摘要： Provided are a tube-type medical needle unit and a method of mounting a plurality of medical sutures in a tube-type needle. The tube-type medical needle unit includes a tube-type needle including an end in the shape of a probe and including a communication hole formed therein to communicate the end with another end and a plurality of sutures inserted into the communication hole of the tube-type needle, the sutures including adhesion protrusions formed on surfaces thereof, in which the plurality of sutures are arranged in parallel and mounted in the tube-type needle.

摘要翻译： 提供一种管式医用针单元以及将多根医用缝线安装在管型针中的方法。 管型医用针单元包括管型针，其包括探针形状的端部，并且包括形成在其中的连通孔，用于将端部与另一端连通，以及插入到管状接头的连通孔中的多个缝合线， 所述缝合线包括在其表面上形成的粘附突起，其中所述多个缝线平行布置并安装在所述管型针中。