公开(公告)号：US20150183767A1

公开(公告)日：2015-07-02

申请号：US14416324

申请日：2013-07-19

申请人： Hetero Research Foundation

发明人： Bandi Parthasaradhi Reddy ,  Kura Rathnakar Reddy ,  Dasari Muralidhara Reddy ,  Matta Ramakrishna Reddy ,  Bandi Vamsi Krishna

IPC分类号： C07D413/10 ,  A61K31/4245 ,  C07D413/14

CPC分类号： C07D413/10 ,  A61K31/4245 ,  B01F3/0807 ,  B01F11/0028 ,  B01F15/00331 ,  B01F15/00389 ,  B01F15/00396 ,  B01F15/00538 ,  B01F15/026 ,  B01F2215/0073 ,  C07B2200/13 ,  C07D413/14 ,  C12M45/02 ,  G01N1/38

摘要： The present invention provides a novel amorphous Form of azilsartan acid, process for its preparation and pharmaceutical compositions comprising it. The present invention also provides novel crystalline Forms of azilsartan medoxomil, processes for their preparations and pharmaceutical compositions comprising them. The present invention further provides a novel amorphous Form of azilsartan medoxomil potassium, process for its preparation and pharmaceutical compositions comprising it. The present invention further provides a novel process for the preparation of azilsartan medoxomil potassium crystalline Form II.

摘要翻译： 本发明提供了一种新型的无定形形式的吖唑烷酸，其制备方法和包含它的药物组合物。 本发明还提供了新型的吖唑烷酮莫昔米尔的结晶形式，其制备方法和包含它们的药物组合物。 本发明进一步提供了一种新型的无定形形式的吖唑烷酮莫昔米尔钾，其制备方法和包含它的药物组合物。 本发明还提供了制备吖唑烷酮米诺钾结晶II型的新方法。

公开(公告)号：US20150291574A1

公开(公告)日：2015-10-15

申请号：US14589575

申请日：2013-07-08

申请人： Bandi PARTHASARADHI REDDY ,  Kura RATHNAKAR REDDY ,  Dasari MURALIDHARA REDDY ,  Matta RAMAKRISHNA REDDY ,  HETERO RESEARCH FOUNDATION

发明人： Bandi Parthasaradhi Reddy ,  Kura Rathnakar Reddy ,  Dasari Muralidhara Reddy ,  Matta Ramakrishna Reddy ,  Bandi Vamsi Krishna

IPC分类号： C07D413/14

CPC分类号： C07D413/14 ,  C07B2200/13

摘要： The present invention provides a novel crystalline Form of azilsartan acid, process for its preparation and pharmaceutical compositions comprising it. The present invention also provides a novel crystalline Form of azilsartan medoxomil potassium, process for its preparation and pharmaceutical compositions comprising it.

摘要翻译： 本发明提供了一种新型的唑来硫酸结晶形式，其制备方法和包含它的药物组合物。 本发明还提供了一种新型的吖唑烷酮莫昔米尔钾的结晶形式，其制备方法和包含它的药物组合物。

公开(公告)号：US09624207B2

公开(公告)日：2017-04-18

申请号：US14416324

申请日：2013-07-19

申请人： HETERO RESEARCH FOUNDATION

发明人： Bandi Parthasaradhi Reddy ,  Kura Rathnakar Reddy ,  Dasari Muralidhara Reddy ,  Matta Ramakrishna Reddy ,  Bandi Vamsi Krishna

IPC分类号： C07D413/10 ,  C07D413/14 ,  A61K31/4245 ,  B01F3/08 ,  B01F11/00 ,  B01F15/00 ,  B01F15/02 ,  C12M1/33 ,  G01N1/38

CPC分类号： C07D413/10 ,  A61K31/4245 ,  B01F3/0807 ,  B01F11/0028 ,  B01F15/00331 ,  B01F15/00389 ,  B01F15/00396 ,  B01F15/00538 ,  B01F15/026 ,  B01F2215/0073 ,  C07B2200/13 ,  C07D413/14 ,  C12M45/02 ,  G01N1/38

摘要： The present invention provides a novel amorphous Form of azilsartan acid, process for its preparation and pharmaceutical compositions comprising it. The present invention also provides novel crystalline Forms of azilsartan medoxomil, processes for their preparations and pharmaceutical compositions comprising them. The present invention further provides a novel amorphous Form of azilsartan medoxomil potassium, process for its preparation and pharmaceutical compositions comprising it. The present invention further provides a novel process for the preparation of azilsartan medoxomil potassium crystalline Form II.