-
公开(公告)号：US09675288B2
公开(公告)日：2017-06-13
申请号：US14764528
申请日：2013-01-29
发明人： Mineo Yamakawa , Zhiyong Li
IPC分类号： B01L3/00 , A61B5/1459 , G01N21/65 , A61B5/00 , G01N21/25
CPC分类号： A61B5/1459 , A61B5/6848 , A61B2562/0238 , A61B2562/12 , G01N21/658 , G01N2021/258 , G01N2201/061 , G01N2201/068
摘要： According to an example, an apparatus for performing spectroscopy includes an elongated substrate having a shape and size to be inserted into a specimen, wherein the elongated substrate has a first end and a second end. The apparatus also includes a plurality of surface-enhanced spectroscopy (SES) elements positioned on an exterior surface of the elongated substrate at a location between the first end and the second end of the elongated substrate.
-
公开(公告)号：US10969339B2
公开(公告)日：2021-04-06
申请号：US16838662
申请日：2020-04-02
发明人： Charles M. Santori , James William Stasiak , Francesco Aieta , Anita Rogacs , Mineo Yamakawa , Kenneth Ward
IPC分类号： G01N21/65
摘要： Optical readers are disclosed in examples herein. An example optical reader including a light source to emit a light beam; and a spot pattern generator to receive the light beam and to generate a two-dimensional spot array from the light beam, the two-dimensional spot array to be directed toward a substrate having nanostructures, the two-dimensional spot array to be sensed to detect a presence or an absence of a substance of interest on the substrate.
-
公开(公告)号：US09879299B2
公开(公告)日：2018-01-30
申请号：US14475532
申请日：2014-09-02
发明人： Mineo Yamakawa , Zhiyong Li
IPC分类号： C12Q3/00 , C12Q1/02 , C12M1/34 , G01N33/483
CPC分类号： C12Q1/02 , C12M41/36 , C12M41/46 , C12Q3/00 , G01N33/4833
摘要： The present disclosure is drawn to a device for monitoring and controlling live cells and associated methods. In an example, the device can include a plurality of elongated nanostructures affixed to a substrate. The elongated nanostructures can each have an attachment end and a free end opposite the attachment end. The free end includes a metal and the attachment end is affixed to the substrate. The device can further include a functionalization layer that is coated on the free end of at least a portion of the plurality of elongated nanostructures. The functionalization layer can be formulated to retain live cells, and the device can be configured to be used in conjunction with a detector, such as a Raman spectrometer, in order to monitor growth of live cells.
-
公开(公告)号：US08810780B1
公开(公告)日：2014-08-19
申请号：US13755801
申请日：2013-01-31
发明人： Steven J Barcelo , Zhiyong Li , Gary Gibson , Mineo Yamakawa , Ansoon Kim
摘要： A strain gauge or other device may include a deformable medium and discrete plasmon supporting structures arranged to create one or more plasmon resonances that change with deformation of the medium and provide the device with an optical characteristic that indicates the deformation of the medium.
摘要翻译： 应变计或其它装置可以包括可变形介质和离散的等离子体支撑结构，其布置成产生一个或多个等离子体共振，其随着介质的变形而变化，并为该装置提供指示介质变形的光学特性。
-
公开(公告)号：US20140212867A1
公开(公告)日：2014-07-31
申请号：US13754860
申请日：2013-01-30
发明人： Mineo Yamakawa , Zhiyong Li
CPC分类号： C12Q1/02 , C12M41/36 , C12M41/46 , C12Q3/00 , G01N33/4833
摘要： The present disclosure is drawn to a device for monitoring and controlling live cells and associated methods. In an example, the device can include a plurality of elongated nanostructures affixed to a substrate. The elongated nanostructures can each have an attachment end and a free end opposite the attachment end. The free end includes a metal and the attachment end is affixed to the substrate. The device can further include a functionalization layer that is coated on the free end of at least a portion of the plurality of elongated nanostructures. The functionalization layer can be formulated to retain live cells, and the device can be configured to be used in conjunction with a detector, such as a Raman spectrometer, in order to monitor growth of live cells.
摘要翻译： 本公开涉及用于监测和控制活细胞和相关方法的装置。 在一个示例中，该装置可以包括固定到基底上的多个细长的纳米结构。 细长的纳米结构可以各自具有附接端和与附接端相对的自由端。 自由端包括金属，并且附接端固定到基底。 该装置还可以包括涂覆在多个细长纳米结构的至少一部分的自由端上的官能化层。 功能化层可以配制成保留活细胞，并且该装置可被配置为与诸如拉曼光谱仪的检测器结合使用，以便监测活细胞的生长。
-
6.发明申请MULTIPLE SPECTRAL MEASUREMENT ACQUISITION APPARATUS AND THE METHODS OF USING SAME 审中-公开多种光谱测量采集装置及其使用方法公开(公告)号：US20150211998A1
公开(公告)日：2015-07-30
申请号：US14414206
申请日：2012-10-31
发明人： Huei Pei Kuo , Zhiyong Li , Shih-Yuan Wang , Alexandre M. Bratkovski , Steven Barcelo , Ansoon Kim , Gary Gibson , Mineo Yamakawa
CPC分类号： G01N21/65 , G01N21/64 , G01N2201/06113
摘要： A system includes an illumination source, a detector and a processor. The detector acquires spectral measurements of a sample under test under at least one varying condition. The processor processes the measurements to generate at least one spectral representation that includes Raman spectra and at least one spectral representation that includes non-Raman spectra.
摘要翻译： 系统包括照明源，检测器和处理器。 检测器在至少一个变化的条件下获得被测样品的光谱测量。 处理器处理测量以产生包括拉曼光谱和包括非拉曼光谱的至少一个光谱表示的至少一个光谱表示。
-
公开(公告)号：US10222336B2
公开(公告)日：2019-03-05
申请号：US14414206
申请日：2012-10-31
发明人： Huei Pei Kuo , Zhiyong Li , Shih-Yuan Wang , Alexandre M Bratkovski , Steven Barcelo , Ansoon Kim , Gary Gibson , Mineo Yamakawa
摘要： A system includes an illumination source, a detector and a processor. The detector acquires spectral measurements of a sample under test under at least one varying condition. The processor processes the measurements to generate at least one spectral representation that includes Raman spectra and at least one spectral representation that includes non-Raman spectra.
-
公开(公告)号：US20140370493A1
公开(公告)日：2014-12-18
申请号：US14475532
申请日：2014-09-02
发明人： Mineo Yamakawa , Zhiyong Li
IPC分类号： C12Q1/02
CPC分类号： C12Q1/02 , C12M41/36 , C12M41/46 , C12Q3/00 , G01N33/4833
摘要： The present disclosure is drawn to a device for monitoring and controlling live cells and associated methods. In an example, the device can include a plurality of elongated nanostructures affixed to a substrate. The elongated nanostructures can each have an attachment end and a free end opposite the attachment end. The free end includes a metal and the attachment end is affixed to the substrate. The device can further include a functionalization layer that is coated on the free end of at least a portion of the plurality of elongated nanostructures. The functionalization layer can be formulated to retain live cells, and the device can be configured to be used in conjunction with a detector, such as a Raman spectrometer, in order to monitor growth of live cells.
摘要翻译： 本公开涉及用于监测和控制活细胞和相关方法的装置。 在一个示例中，该装置可以包括固定到基底上的多个细长的纳米结构。 细长的纳米结构可以各自具有附接端和与附接端相对的自由端。 自由端包括金属，并且附接端固定到基底。 该装置还可以包括涂覆在多个细长纳米结构的至少一部分的自由端上的官能化层。 功能化层可以配制成保留活细胞，并且该装置可被配置为与诸如拉曼光谱仪的检测器结合使用，以便监测活细胞的生长。
-
公开(公告)号：US08711351B1
公开(公告)日：2014-04-29
申请号：US13753450
申请日：2013-01-29
发明人： Gary Gibson , Steven J Barcelo , Shih-Yuan Wang , Zhiyong Li , Huei Pei Kuo , Ansoon Kim , Alexandre M Bratkovski , Zhang-Lin Zhou , Mineo Yamakawa
IPC分类号： G01J3/44
CPC分类号： G01N21/658
摘要： Scattering spectroscopy employs a scattering spectroscopy enhancing structure having a hotspot on a first side of a substrate and a nanopore in the substrate, where the nanopore is aligned with the hotspot.
摘要翻译： 散射光谱学使用散射光谱增强结构，其在衬底的第一侧具有热点，并且在衬底中使用纳米孔，其中纳米孔与热点对准。
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.015 秒)