摘要:
The present invention provides target proteins and target genes for bioactive substances such as drugs, and means that enable the development of novel bioactive substances using the same. More specifically, the present invention provides target proteins and target genes for bioactive substances; screening methods for substances capable of regulating bioactivities; bioactivity regulators; a bioactive substance derivative production method; a complex comprising a bioactive substance and a target protein, and a method of producing the complex; and kits comprising a bioactive substance or a salt thereof; determination methods for the onset or risk of onset of a specified disease or condition, determination methods for susceptibility to a bioactive substance, and determination kits used for the determination methods, and the like.
摘要:
The problems of the present invention are to provide target proteins and target genes for bioactive substances such as drugs, and means that enable the development of novel bioactive substances using the same. The present invention provides target proteins and target genes for bioactive substances; screening methods for substances capable of regulating bioactivities; bioactivity regulators; a bioactive substance derivative production method; a complex comprising a bioactive substance and a target protein, and a method of producing the complex; and kits comprising a bioactive substance or a salt thereof; determination methods for the onset or risk of onset of a specified disease or condition, determination methods for susceptibility to a bioactive substance, and determination kits used for the determination methods, and the like.
摘要:
Various biomolecules can be firmly immobilized to a substrate by a method which comprises contacting a solution containing biomolecules provided with at least one tag with an immobilization substrate which has (i) binding sites for the biomolecule tag or tags, and (ii) activated reactive groups which are capable of forming covalent bonds with the biomolecules, to covalently bind the biomolecules interacting with the tag binding sites to the immobilization substrate.
摘要:
A swimming element enjoying system capable of applying an external stimulus to a swimming element moved at a predetermined rhythm, to thereby permit the swimming element to carry out different motion, to thereby provide an observer with a fresh surprise, so that the observer may be soothed or healed. A swimming element made in imitation of an aquatic life and a drive unit for driving the swimming element each are provided with a permanent magnet. The permanent magnet of the drive unit is rotated, to thereby permit an attracting/repulsing action to be carried out between the permanent magnets, leading to random vertical motion of said swimming element. Motion of the swimming element is randomly varied when a sensor detects an external stimulus.
摘要:
To obtain a receiver circuit unit for radio controlled toys configured such that the drive of a plurality of types of radio controlled toys can be controlled by a single transmitter by removably mounting the receiver circuit unit as a separate item. To provide a receiver circuit unit for radio controlled toys configured such that a receiver circuit unit mounting portion is provided in each of a plurality of types of radio controlled toys containing a drive mechanism, and a single receiver circuit unit is interchangeably and removably mounted on the receiver circuit unit mounting portion, whereby the drive of the plurality of types of radio controlled toys can be controlled by a single transmitter.
摘要:
A toy automobile having selective drive wheels comprising a body, a chassis and pairs of front and rear wheels, in which either a front wheel windup spring drive unit or a freewheel holder along with a front axle is detachably arranged in a front space of the chassis, and in which either a rear wheel windup spring drive unit or a freewheel holder along with a rear axle is detachably arranged in a rear space of the chassis, whereby a selection between front wheel drive, rear wheel drive, four-wheel drive or four-freewheel is made possible.