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12 条记录 (耗时 0.041 秒)

    Cephem compounds
    5.
    发明授权
    Cephem compounds 失效
    头孢烯化合物

    公开(公告)号：US07192943B2

    公开(公告)日：2007-03-20

    申请号：US10942916

    申请日：2004-09-17

    申请人： Toshio Yamanaka ,  Kenji Murano ,  Ayako Toda ,  Hidenori Ohki ,  Masaru Oogaki ,  Shinya Okuda ,  Kohji Kawabata ,  Satoshi Inoue ,  Keiji Misumi ,  Kenji Itoh ,  Kenji Sato

    发明人： Toshio Yamanaka ,  Kenji Murano ,  Ayako Toda ,  Hidenori Ohki ,  Masaru Oogaki ,  Shinya Okuda ,  Kohji Kawabata ,  Satoshi Inoue ,  Keiji Misumi ,  Kenji Itoh ,  Kenji Sato

    IPC分类号： C07D501/46 ,  A61K31/546 ,  A61P31/04

    CPC分类号： C07D501/00 ,  Y02P20/55

    摘要： The present invention relates to a compound of the formula [I]: wherein R1 is lower alkyl or hydroxy(lower)alkyl, and R2 is hydrogen or amino protecting group, or R1 and R2 are bonded together and form lower alkylene; R is -A-R6 wherein A is bond, —NHCO—(CH2CO)n—, lower alkylene, —NH—CO—CO— or the like, and R6 is wherein R7, R8, R9 and R10 are independently amino, guanidino, amidino or the like; R4 is carboxy or protected carboxy; and R5 is amino or protected amino, or a pharmaceutically acceptable salt thereof, a process for preparing a compound of the formula [I], and a pharmaceutical composition comprising a compound of the formula [I] in admixture with a pharmaceutically acceptable carrier.

    摘要翻译： 本发明涉及式[I]化合物：其中R 1是低级烷基或羟基（低级）烷基，R 2是氢或氨基保护基 或R 1和R 2结合在一起形成低级亚烷基; R为-AR 6，其中A为键，-NHCO-（CH 2 CO 2）n - ，低级亚烷基，-NH-CO- CO-等，并且R 6是其中R 7，R 8，R 9和R 9， 胍基10是独立的氨基，胍基，脒基等; R 4是羧基或被保护的羧基; 和R 5是氨基或被保护的氨基或其药学上可接受的盐，制备式[I]化合物的方法，以及药物组合物，其包含式[I]化合物 与药学上可接受的载体混合。

    Cephem compounds
    6.
    发明申请
    Cephem compounds 失效
    头孢烯化合物

    公开(公告)号：US20050096306A1

    公开(公告)日：2005-05-05

    申请号：US10942916

    申请日：2004-09-17

    申请人： Toshio Yamanaka ,  Kenji Murano ,  Ayako Toda ,  Hidenori Ohki ,  Masaru Oogaki ,  Shinya Okuda ,  Kohji Kawabata ,  Satoshi Inoue ,  Keiji Misumi ,  Kenji Itoh ,  Kenji Sato

    发明人： Toshio Yamanaka ,  Kenji Murano ,  Ayako Toda ,  Hidenori Ohki ,  Masaru Oogaki ,  Shinya Okuda ,  Kohji Kawabata ,  Satoshi Inoue ,  Keiji Misumi ,  Kenji Itoh ,  Kenji Sato

    IPC分类号： A61K31/546 ,  C07D501/00 ,  A61K31/545 ,  C07D501/14

    CPC分类号： C07D501/00 ,  Y02P20/55

    摘要： The present invention relates to a compound of the formula [I]: wherein R1 is lower alkyl or hydroxy(lower)alkyl, and R2 is hydrogen or amino protecting group, or R1 and R2 are bonded together and form lower alkylene; R is -A-R6 wherein A is bond, —NHCO—(CH2CO)n—, lower alkylene, —NH—CO—CO— or the like, and R6 is wherein R7, R8, R9 and R10 are independently amino, guanidino, amidino or the like; R4 is carboxy or protected carboxy; and R5 is amino or protected amino, or a pharmaceutically acceptable salt thereof, a process for preparing a compound of the formula [I], and a pharmaceutical composition comprising a compound of the formula [I] in admixture with a pharmaceutically acceptable carrier.

    摘要翻译： 本发明涉及式[I]化合物：其中R 1是低级烷基或羟基（低级）烷基，R 2是氢或氨基保护基 或R 1和R 2结合在一起形成低级亚烷基; R为-AR 6，其中A为键，-NHCO-（CH 2 CO 2）n - ，低级亚烷基，-NH-CO- CO-等，并且R 6是其中R 7，R 8，R 9和R 9， 胍基10是独立的氨基，胍基，脒基等; R 4是羧基或被保护的羧基; 和R 5是氨基或被保护的氨基或其药学上可接受的盐，制备式[I]化合物的方法，以及药物组合物，其包含式[I]化合物 与药学上可接受的载体混合。

    Manifold valve having position detecting mechanism
    10.
    发明授权
    Manifold valve having position detecting mechanism 有权
    歧管阀具有位置检测机构

    公开(公告)号：US06923207B2

    公开(公告)日：2005-08-02

    申请号：US10407429

    申请日：2003-04-07

    申请人： Keiji Misumi

    发明人： Keiji Misumi

    IPC分类号： F16K27/00 ,  F15B13/00 ,  F15B13/04 ,  F15B13/08 ,  F16K31/42 ,  F16K37/00 ,  F15B13/043

    CPC分类号： F15B13/0839 ,  F15B13/0402 ,  F15B13/0817 ,  F15B13/0821 ,  F15B13/0853 ,  F15B13/0857 ,  F15B13/086 ,  F15B13/0864 ,  F15B13/0875 ,  F15B2013/0409 ,  F16K31/426 ,  Y10T137/8175 ,  Y10T137/8242 ,  Y10T137/8326 ,  Y10T137/86614 ,  Y10T137/87885

    摘要： In a manifold valve, a part housing chamber and a fist recessed portion are provided to a casing of a selector valve, position sensors for detecting an operating position of a spool are housed in the part housing chamber, a first relay connector connected to both the position sensors and pilot valves is housed in the first recessed portion, a second recessed portion corresponding to the first recessed portion and a substrate housing chamber are provided to a manifold base, a second relay connector to be electrically connected to the first relay connector by mounting the selector valve onto a placing face is housed in the second recessed portion, and a main wiring substrate electrically connected to the second relay connector is housed in the substrate housing chamber.

    摘要翻译： 在歧管阀中，部件容纳室和第一凹部设置在选择阀的壳体上，用于检测阀芯的操作位置的位置传感器容纳在部件容纳室中，第一中继连接器连接到两个 位置传感器和先导阀容纳在第一凹部中，与第一凹部对应的第二凹部和基板容纳室设置在歧管基座上，第二中继连接器通过安装而与第一中继连接器电连接 将选择阀放置在放置面上，容纳在第二凹部中，与第二中继连接器电连接的主配线基板容纳在基板容纳室中。