公开(公告)号：US06624336B1

公开(公告)日：2003-09-23

申请号：US09959715

申请日：2001-11-05

申请人： Toru Sasaki ,  Tetsuhiro Furukawa ,  Toru Yoshida ,  Yutaka Ohnishi ,  Hiroyuki Monzen ,  Hideo Miyata ,  Kohei Morikawa

发明人： Toru Sasaki ,  Tetsuhiro Furukawa ,  Toru Yoshida ,  Yutaka Ohnishi ,  Hiroyuki Monzen ,  Hideo Miyata ,  Kohei Morikawa

IPC分类号： C07C3346

CPC分类号： C07C47/55 ,  B01J25/02 ,  B01J27/055 ,  C07C29/141 ,  C07C43/313 ,  C07C45/44 ,  C07C45/515 ,  C07C33/46

摘要： The present invention relates to a process by a series of reactions using tetrafluorocyanobenzens as material for producing tetrafluorobenzenemethanols, tetrafluorobenzenecarbaldehyde dialkylacetals and tetrafluorobenzenecarbaldehydes in a high purity and a high yield which are useful as intermediates in the production of cyclopropanecarboxylic acid esters having insecticidal action, and also relates to a novel tetrafluorobenzenecarbaldehyde dimethylacetal.

摘要翻译： 本发明涉及一种通过一系列反应的方法，该反应使用四氟氰基化合物作为生产具有杀虫作用的环丙烷羧酸酯的中间体而制备四氟苯甲醇，四氟苯甲醛二烷基缩醛和四氟苯甲醛的高纯度和高收率的材料， 涉及一种新的四氟苯甲醛二甲缩醛。

公开(公告)号：US5859289A

公开(公告)日：1999-01-12

申请号：US814830

申请日：1997-03-11

申请人： Hideo Miyata ,  Toru Sasaki ,  Kohei Morikawa

发明人： Hideo Miyata ,  Toru Sasaki ,  Kohei Morikawa

IPC分类号： A01N57/20 ,  C07F9/38

CPC分类号： A01N57/20 ,  C07F9/3813

摘要： The present invention provides a method for isolating N-phosphonomethylglycine which comprises adding an acid to precipitate salts from an aqueous solution of an alkali metal salt and/or an alkaline earth metal salt of N-phosphonomethylglycine solution to neutralize and adjust the same to a pH of 2.5 or higher, removing the precipitated salts, and adjusting the pH to 2.5 or lower to crystallize N-phosphonomethylglycine. N-phosphonomethylglycine is thus isolated and purified in high purity and good yield.

摘要翻译： 本发明提供了一种分离N-膦酰基甲基甘氨酸的方法，该方法包括加入酸以从N-膦酰基甲基甘氨酸溶液的碱金属盐和/或碱土金属盐的水溶液中沉淀出盐，以将其调节至pH 2.5或更高，去除沉淀的盐，并将pH调节至2.5以下以结晶N-膦酰基甲基甘氨酸。 因此N-膦酰基甲基甘氨酸以高纯度和良好的产率分离和纯化。

公开(公告)号：US5750774A

公开(公告)日：1998-05-12

申请号：US814827

申请日：1997-03-11

申请人： Hideo Miyata ,  Toru Sasaki ,  Kohei Morikawa

发明人： Hideo Miyata ,  Toru Sasaki ,  Kohei Morikawa

IPC分类号： C07F9/38

CPC分类号： C07F9/3813

摘要： The present invention provides a method for producing N-phosphonomethylglycine which comprises reacting an aminomethylphosphonic acid with glycolonitrile, or formaldehyde and hydrogen cyanide in situ, under an alkaline condition to convert the aminomethylphosphonic acid into an N-phosphonomethylglycinonitrile salt or a mixture of an N-phosphonomethylglycinonitrile salt and N-phosphonomethylglycinonitrile, and then hydrolyzing the product under an acidic condition. Subsequent to a reaction step for the production of N-phosphonomethylglycinonitrile, the reaction product is hydrolyzed by adding thereto an acid in a prescribed amount. Accordingly, the use of a large amount of an alkaline metal hydroxide and the neutralization step for obtaining N-phosphonomethylglycine after hydrolysis, which steps are necessary in a conventional alkali hydrolysis method, are omitted in the present invention.

摘要翻译： 本发明提供了一种N-膦酰基甲基甘氨酸的制备方法，该方法包括使氨基甲基膦酸与乙醇腈或甲醛和氰化氢在碱性条件下原位反应，将氨基甲基膦酸转化为N-膦酰基甲基甘氨腈盐或N- 膦酰基甲基甘氨腈盐和N-膦酰基甲基甘氨腈，然后在酸性条件下水解产物。 在制备N-膦酰基甲基甘氨腈的反应步骤之后，通过向其中加入规定量的酸来水解反应产物。 因此，在本发明中，省略了大量碱金属氢氧化物的使用和水解后得到N-膦酰基甲基甘氨酸的中和工序，这些步骤在常规碱水解法中是必需的。

公开(公告)号：US5324855A

公开(公告)日：1994-06-28

申请号：US961363

申请日：1992-10-15

申请人： Kohei Morikawa ,  Toru Sasaki ,  Kazuhiro Omori ,  Hideo Miyata ,  Yoko Suguri

发明人： Kohei Morikawa ,  Toru Sasaki ,  Kazuhiro Omori ,  Hideo Miyata ,  Yoko Suguri

IPC分类号： C07F9/24 ,  C07F9/38

CPC分类号： C07F9/3813

摘要： N-acylaminomethylphosphonic acid is prepared from an N-methylolamide compound and a phosphorus trihalide. The starting compounds are mixed and heated in an aprotic solvent in the presence of water in a 0.25 to 2.5 times molar amount relative to the phosphorus trihalide at 60.degree. to 160.degree. C., and the reaction mixture is contacted with water. The N-methylolamide compound is a compound selected from the group consisting of N-methylol-lower alkylamides and N-methylolarylamides. The phosphorus trihalide is preferably phosphorus trichloride. As the aprotic solvent is used one or more of hydrocarbons, halogenated hydrocarbons, ethers, polyethers, nitriles, and aromatic nitro compounds. The mixing may be carried out at a temperature of 60.degree. C. The water present at the initiation of the reaction is in a 1.0 to 1.8 times molar amount relative to the phosphorus trihalide.

摘要翻译： N-酰氨基甲基膦酸由N-羟甲基酰胺化合物和三卤化磷制备。 将起始化合物在非质子溶剂中在相对于三卤化磷在0.25至160℃下以0.25至2.5倍摩尔量存在的水中加热，并将反应混合物与水接触。 N-羟甲基酰胺化合物是选自N-羟甲基 - 低级烷基酰胺和N-羟甲基芳基酰胺的化合物。 三卤化磷优选为三氯化磷。 由于非质子溶剂使用一种或多种烃，卤代烃，醚，聚醚，腈和芳族硝基化合物。 混合可以在60℃的温度下进行。反应开始时存在的水相对于三卤化磷的摩尔量为1.0〜1.8倍。

公开(公告)号：US5679844A

公开(公告)日：1997-10-21

申请号：US605056

申请日：1996-03-01

申请人： Hideo Miyata ,  Toru Sasaki ,  Kohei Morikawa

发明人： Hideo Miyata ,  Toru Sasaki ,  Kohei Morikawa

IPC分类号： C07F9/38

CPC分类号： C07F9/3813

摘要： The present invention relates to a method of manufacturing N-phosphonomethylglycine and salts thereof, which can be biologically degraded, and have superior effectiveness against weeds and are useful as herbicides, by means of alkali hydrolysis of N-phosphonomethylglycinonitrile. In order to obtain high yields of the desired high purity, the amount of salt produced as a by-product is reduced by using the alkali so as to result in not less than 2 molecules and less than 3 molecules of the alkali for each molecule of N-phosphonomethylglycinonitrile when the alkali is monovalent, and not less than 1 molecule and less than 1.5 molecules of the alkali for each molecule of N-phosphonomethylglycinonitrile when the alkali is divalent.

摘要翻译： PCT No.PCT / JP95 / 01327 Sec。 371日期1996年3月1日 102（e）1996年3月1日PCT PCT 1995年7月3日PCT公布。 出版物WO96 / 01264 日期1996年1月18日本发明涉及N-膦酰基甲基甘氨酸及其盐的制造方法，其可以生物降解，并且对于杂草具有优异的有效性，并且通过N-膦酰基甲基甘氨腈的碱水解可用作除草剂。 为了获得所需高纯度的高产率，通过使用碱来降低作为副产物产生的盐的量，从而得到每个分子的不少于2个分子和少于3个碱的分子 当碱为二价时，N-膦酰基甲基甘氨腈为N-膦酰基甲基甘氨腈，当碱为二价时，每分子N-膦酰基甲基甘氨腈为1分子以上且小于1.5分子的碱。

公开(公告)号：US07569718B2

公开(公告)日：2009-08-04

申请号：US10513370

申请日：2003-07-23

申请人： Toru Sasaki ,  Yutaka Onishi ,  Kohei Morikawa

发明人： Toru Sasaki ,  Yutaka Onishi ,  Kohei Morikawa

IPC分类号： C07C255/49

CPC分类号： C07C253/30 ,  C07C255/50

摘要： The invention enables reduction of catalyst in producing tetrafluorobenzonitrile by decyanation of one cyano group of tetrafluorodicyanobenzene by using a synthetic zeolite, particularly Zeolite 3A, 4A or 5A, in the reaction. Therefore, the invention provides an industrially useful process capable of producing tetrafluorobenzonitrile, a useful agrochemical and drug intermediate, by hydrogenolysis of tetrafluorodicyanobenzene to decyanate one cyano group with the use of catalyst in small amounts.

摘要翻译： 本发明可以通过在反应中使用合成沸石，特别是沸石3A，4A或5A脱卤一个氰基的四氟二氰基苯来制备四氟苄腈来制备催化剂。 因此，本发明提供了一种工业上有用的方法，其能够通过使用少量催化剂将四氟二氰基苯氢解成一个氰基，从而生产四氟苄腈，一种有用的农药和药物中间体。

公开(公告)号：US20050131245A1

公开(公告)日：2005-06-16

申请号：US10513370

申请日：2003-07-23

申请人： Toru Sasaki ,  Yutaka Onishi ,  Kohei Morikawa

发明人： Toru Sasaki ,  Yutaka Onishi ,  Kohei Morikawa

IPC分类号： B01J29/74 ,  C07B61/00 ,  C07C253/30 ,  C07C255/50

CPC分类号： C07C253/30 ,  C07C255/50

摘要： The invention enables reduction of catalyst in producing tetrafluorobenzonitrile by decyanation of one cyano group of tetrafluorodicyanobenzene by using a synthetic zeolite, particularly Zeolite 3A, 4A or 5A, in the reaction. Therefore, the invention provides an industrially useful process capable of producing tetrafluorobenzonitrile, a useful agrochemical and drug intermediate, by hydrogenolysis of tetrafluorodicyanobenzene to decyanate one cyano group with the use of catalyst in small amounts.

摘要翻译： 本发明可以通过在反应中使用合成沸石，特别是沸石3A，4A或5A脱卤一个氰基的四氟二氰基苯来制备四氟苄腈来制备催化剂。 因此，本发明提供了一种工业上有用的方法，其能够通过使用少量催化剂将四氟二氰基苯氢解成一个氰基，从而生产四氟苄腈，一种有用的农药和药物中间体。

公开(公告)号：US11666759B2

公开(公告)日：2023-06-06

申请号：US17069193

申请日：2020-10-13

申请人： Shinji Sato ,  Sukchan Kim ,  Taishi Watanabe ,  Yuki Mitani ,  Yuki Miyano ,  Shigenori Kawabata ,  Toru Sasaki

发明人： Shinji Sato ,  Sukchan Kim ,  Taishi Watanabe ,  Yuki Mitani ,  Yuki Miyano ,  Shigenori Kawabata ,  Toru Sasaki

IPC分类号： A61N1/36

CPC分类号： A61N1/36031 ,  A61N1/36034

摘要： A nerve stimulating apparatus includes a plurality of stimulating units configured to respectively apply stimuli to a plurality of nerve regions branching from a particular nerve region of a living body, and a stimulation timing controller configured to set generating timings of respectively generating the stimuli at the plurality of stimulating units. The stimulation timing controller sets the generating timings of generating the stimuli at the plurality of stimulating units based on response results of the particular nerve region, the response results being obtained in response to the stimuli that are respectively generated at the plurality of stimulating units and that are respectively applied to the plurality of nerve regions, and the response results being measured by a biometric information measuring apparatus that measures biometric information.

公开(公告)号：US08903423B2

公开(公告)日：2014-12-02

申请号：US11887170

申请日：2006-02-24

申请人： Yoichiro Sako ,  Toshiro Terauchi ,  Masamichi Asukai ,  Mitsuru Takehara ,  Takatoshi Nakamura ,  Makoto Inoue ,  Kosei Yamashita ,  Yasushi Miyajima ,  Toru Sasaki ,  Masafumi Matsuda

发明人： Yoichiro Sako ,  Toshiro Terauchi ,  Masamichi Asukai ,  Mitsuru Takehara ,  Takatoshi Nakamura ,  Makoto Inoue ,  Kosei Yamashita ,  Yasushi Miyajima ,  Toru Sasaki ,  Masafumi Matsuda

IPC分类号： H04W24/00 ,  A63F13/30 ,  H04M1/725 ,  H04W8/00 ,  H04L29/06 ,  H04W4/02 ,  H04W8/18

CPC分类号： A63F13/12 ,  A63F13/327 ,  A63F2300/204 ,  A63F2300/5573 ,  H04L67/38 ,  H04M1/7253 ,  H04M1/72572 ,  H04M2250/04 ,  H04M2250/12 ,  H04W4/02 ,  H04W8/005 ,  H04W8/18

摘要： A data communication apparatus capable of creating a new type of communication is provided. Motion information obtaining means 33 obtains information on the motion of an arbitrary apparatus. An other-party apparatus motion determination section 21 makes a determination as to the motion of the arbitrary apparatus on the basis of the information on the motion of the arbitrary apparatus, the information being obtained by the motion information obtaining means 33. A communication determination section 22 determines whether or not communication is to be performed with an arbitrary apparatus on the basis of the motion determination output by the other-party apparatus motion determination section 21. When it is determined by the communication determination section 22 that communication is to be performed, predetermined data communication is started with the arbitrary apparatus.

摘要翻译： 提供能够创建新型通信的数据通信装置。 运动信息获取装置33获得关于任意装置的运动的信息。 另一方装置运动判定部21根据关于任意装置的运动的信息，由运动信息获取装置33获取的信息，对任意装置的运动进行判定。通信判定部 22根据由另一方装置运动判定部21输出的运动判定，判定是否使用任意装置进行通信。当由通信判定部22确定进行通信时， 使用任意装置开始预定的数据通信。

公开(公告)号：US20130235524A1

公开(公告)日：2013-09-12

申请号：US13885620

申请日：2011-10-26

申请人： Junji Baba ,  Masaaki Inoue ,  Shuuji Kameno ,  Toru Sasaki

发明人： Junji Baba ,  Masaaki Inoue ,  Shuuji Kameno ,  Toru Sasaki

IPC分类号： H05K7/20

CPC分类号： H05K7/20136 ,  H05K7/1452 ,  H05K7/1457 ,  H05K7/20727

摘要： In an electronic device, when a 48 V feed system is shifted to a 12 V feed system, in order to supply the same electric power, a current of fourth times needs to flow into a backplane. Also, in an anteroposterior intake and exhaust system, there is a need to form a ventilator through which a cooling air passes in the backplane. Further, there arises a problem that a mechanical strength is deteriorated by provision of the ventilator in the backplane. There is provided a structure in which a pinnate projection is provided on a feed bus bar, and a cooling air is applied to the feed bus bar. Also, the feed bus bar is brought into close contact with an overall surface of the backplane, and electrically and mechanically connected thereto at multiple points, to thereby perform both of cooling and the suppression of stiffness deterioration.

摘要翻译： 在电子设备中，当48V馈电系统移动到12V馈电系统时，为了提供相同的电力，第四次的电流需要流入背板。 此外，在前后进气和排气系统中，需要形成通风机，冷却空气通过该通风机在背板中通过。 此外，存在通过在背板中设置呼吸机而导致机械强度劣化的问题。 提供了一种结构，其中在进料母线上设置有羽状凸起，并且将冷却空气施加到进料母线。 此外，馈送母线与背板的整个表面紧密接触，并且在多个点处电连接和机械连接，从而进行冷却和刚度劣化的抑制。