公开(公告)号：US4877797A

公开(公告)日：1989-10-31

申请号：US67719

申请日：1987-06-15

申请人： Hiroaki Satoh ,  Hiroyasu Koyama ,  Yoshikuni Suzuki ,  Toshiji Sugai ,  Koichi Watanabe

发明人： Hiroaki Satoh ,  Hiroyasu Koyama ,  Yoshikuni Suzuki ,  Toshiji Sugai ,  Koichi Watanabe

IPC分类号： A61K31/4427 ,  A61K31/455 ,  A61K31/47 ,  A61P3/00 ,  A61P9/08 ,  A61P9/12 ,  C07D211/90 ,  C07D401/12

CPC分类号： C07D401/12 ,  C07D211/90

摘要： Compounds are described of the formula ##STR1## wherein R.sub.1 is a nitro or trifluoromethyl group; R.sub.2 is a C.sub.1 -C.sub.6 alkyl group; R.sub.3 is a pyridyl or pyridyl N-oxide group which may be substituted with halogen, hydroxyl, haloalkyl, C.sub.1 -C.sub.6 alkoxy or C.sub.1 -C.sub.6 alkyl and further may be fused with a benzene or naphthalene ring, said ring being optionally substituted with C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, halogen or haloalkyl, and a pharmaceutically acceptable acid addition salt thereof. The compounds of the formula (I) are of vasodilating and blood pressure lowering activities and thus may be useful for the treatment of cardiac diseases, cerebrovascular diseases and hypertension.

公开(公告)号：US6046201A

公开(公告)日：2000-04-04

申请号：US101441

申请日：1998-07-15

申请人： Norio Oshida ,  Yoji Mimaki ,  Hiroaki Satoh ,  Shinji Yokoyama ,  Yukiko Muraki ,  Kazumi Nishimura ,  Tamiko Hamada ,  Einosuke Sakurai ,  Hiroshi Sakai ,  Toshiji Sugai ,  Tomomi Tonoike ,  Koichi Itoh

发明人： Norio Oshida ,  Yoji Mimaki ,  Hiroaki Satoh ,  Shinji Yokoyama ,  Yukiko Muraki ,  Kazumi Nishimura ,  Tamiko Hamada ,  Einosuke Sakurai ,  Hiroshi Sakai ,  Toshiji Sugai ,  Tomomi Tonoike ,  Koichi Itoh

IPC分类号： C07D213/80 ,  C07D213/82 ,  A61K31/495 ,  C07D401/04

CPC分类号： C07D213/80 ,  C07D213/82

摘要： N-(12-Nitroxydodecyl)-6-(4-ethyl or isopropyl-1-piperazinyl)pyridine-3-carboxamide or physiologically acceptable salts thereof. The said compounds have excellent inhibiting activity of cerebral edema, especially ischemic cerebral edema, and inhibiting activity of delayed neuronal death (an inhibiting activity of Ca-influx in neuronal cells). Cerebral edema is a pathologic condition accompanying cerebrovascular disorders, especially the acute stage cerebrovascular disorders and then the compounds are useful as an inhibiting agent for cerebral edema or a therapeutic agent for cerebrovascular disorders. Moreover, because the compounds do hardly show a behavior suppressing action, which is considered to be side effect in treating cerebrovascular disorders at the acute stage, they are an excellent therapeutic agent for, in particular, the acute stage cerebrovascular disorders. Moreover, the compounds show a cerebral protective activity (an anti-anoxic activity), an activity of increasing cerebral blood flow, and an activity of inhibiting lipid peroxidation, and these activities may lead to the increased utility as a therapeutic agent for cerebrovascular disorders.

摘要翻译： PCT No.PCT / JP97 / 04208 Sec。 371日期：1998年7月15日 102（e）日期1998年7月15日PCT 1997年11月19日PCT PCT。 出版物WO98 / 22440 日期1998年5月28日N-（12-硝基十二烷基）-6-（4-乙基或异丙基-1-哌嗪基）吡啶-3-甲酰胺或其生理上可接受的盐。 所述化合物具有优异的脑水肿抑制活性，特别是缺血性脑水肿，抑制延迟性神经元死亡的活性（神经细胞内Ca流入的抑制活性）。 脑水肿是伴随脑血管障碍，特别是急性期脑血管障碍的病理状况，然后该化合物可用作脑水肿的抑制剂或脑血管障碍的治疗剂。 此外，由于化合物几乎不表现出在急性期治疗脑血管障碍中被认为是副作用的行为抑制作用，所以它们是特别是急性期脑血管障碍的优良治疗剂。 此外，化合物显示脑保护活性（抗缺氧活性），增加脑血流量的活性和抑制脂质过氧化的活性，并且这些活性可导致作为脑血管障碍治疗剂的效用增加。

公开(公告)号：US5972943A

公开(公告)日：1999-10-26

申请号：US101760

申请日：1998-07-20

申请人： Norio Oshida ,  Yoji Mimaki ,  Hiroaki Satoh ,  Shinji Yokoyama ,  Yukiko Muraki ,  Kazumi Nishimura ,  Tamiko Hamada ,  Einosuke Sakurai ,  Hiroshi Sakai ,  Toshiji Sugai ,  Tomomi Tonoike ,  Koichi Itoh

发明人： Norio Oshida ,  Yoji Mimaki ,  Hiroaki Satoh ,  Shinji Yokoyama ,  Yukiko Muraki ,  Kazumi Nishimura ,  Tamiko Hamada ,  Einosuke Sakurai ,  Hiroshi Sakai ,  Toshiji Sugai ,  Tomomi Tonoike ,  Koichi Itoh

IPC分类号： C07D213/80 ,  C07D213/82 ,  A61K31/495 ,  C07D401/04

CPC分类号： C07D213/80 ,  C07D213/82

摘要： Pyridinecarboxamide derivatives of the formula ##STR1## (wherein n represents an integer of 14-18, and R represents a hydrogen atom or a straight or branched C.sub.1 -C.sub.4 alkyl group) or physiologically acceptable salts thereof. The compounds have excellent inhibiting activity of cerebral edema, especially ischemic cerebral edema, and inhibiting activity of delayed death of neuronal cells (an inhibiting activity of Ca-influx in neuronal cells). Cerebral edema is a pathologic condition accompanying cerebrovascular disorders, especially the acute stage of cerebrovascular disorders and then the compounds are useful as an agent for inhibiting cerebral edema or a therapeutic agent for cerebrovascular disorders. Moreover, the compounds have no hypotensive action which is considered to be side-effect in treating the acute stage cerebrovascular disorders and hardly show a behavior suppressing action so that they are an excellent therapeutic agent for, in particular, the acute stage cerebrovascular disorders. Moreover, the compounds show a cerebral protective activity (an anti-anoxic activity), an increasing activity of cerebral blood flow, and an inhibiting activity of lipid peroxidation and these activities may lead to the increased utility as a therapeutic agent for cerebrovascular disorders.

摘要翻译： PCT No.PCT / JP97 / 04207 Sec。 371日期：1998年7月20日 102（e）1998年7月20日PCT PCT 1997年11月19日PCT公布。 出版物WO98 / 22439 日期：1998年5月28日下式的吡啶甲酰胺衍生物（其中n表示14-18的整数，R表示氢原子或直链或支链的C 1 -C 4烷基）或其生理学上可接受的盐。 该化合物具有优异的脑水肿抑制活性，特别是缺血性脑水肿，抑制神经元细胞延迟死亡的活性（神经细胞内Ca流入的抑制活性）。 脑水肿是伴随脑血管障碍，特别是脑血管障碍的急性期的病理状况，然后该化合物可用作抑制脑水肿的药剂或脑血管障碍治疗剂。 此外，化合物没有降压作用，被认为在治疗急性期脑血管障碍中具有副作用，并且几乎不显示行为抑制作用，因此它们是特别是急性期脑血管障碍的优良治疗剂。 此外，化合物显示脑保护活性（抗缺氧活性），脑血流量的增加的活性和脂质过氧化的抑制活性，并且这些活性可能导致作为脑血管障碍治疗剂的效用增加。

公开(公告)号：US08253997B2

公开(公告)日：2012-08-28

申请号：US12327130

申请日：2008-12-03

申请人： Toru Nishida ,  Susumu Kibayashi ,  Hiroaki Satoh ,  Takeshi Zengo ,  Tatsumi Komura

发明人： Toru Nishida ,  Susumu Kibayashi ,  Hiroaki Satoh ,  Takeshi Zengo ,  Tatsumi Komura

IPC分类号： H04N1/46 ,  H04N1/034 ,  B41J2/01 ,  B41J3/00 ,  B41J29/38 ,  B41J29/393 ,  B41J2/015 ,  B41J2/14 ,  B41J2/16 ,  B41J2/12

CPC分类号： B41J2/155 ,  B41J2/04508 ,  B41J2/04586

摘要： A correction information creation device including: a recording head; a rotating body; a first detector that detects a period of a pulse signal generated in accordance with rotation of the rotating body; a first calculation section that calculates a period of a clock signal; a second detector that detects a space between corrective images that are formed synchronously with a period of the clock signal, while the rotating body is being rotated at a predetermined rotation speed, by two sets of image formation elements of the recording head; a second calculation section that calculates a distance between a measurement position of a peripheral surface of the rotating body and the axial center of the rotating body; and a memory that stores the calculated distance to serve as information for correcting the period of the clock signal.

摘要翻译： 一种校正信息创建装置，包括：记录头; 旋转体; 第一检测器，其检测根据旋转体的旋转产生的脉冲信号的周期; 计算时钟信号的周期的第一计算部; 第二检测器，通过记录头的两组图像形成元件，在旋转体以预定的转速旋转的同时，检测与时钟信号的周期同步地形成的校正图像之间的空间; 第二计算部，计算旋转体的周面的测量位置与旋转体的轴心之间的距离; 以及存储器，其将所计算的距离存储为用于校正时钟信号的周期的信息。

公开(公告)号：US08002400B2

公开(公告)日：2011-08-23

申请号：US11599941

申请日：2006-11-15

申请人： Susumu Kibayashi ,  Hiroaki Satoh ,  Akira Mihara ,  Masahiko Fujii

发明人： Susumu Kibayashi ,  Hiroaki Satoh ,  Akira Mihara ,  Masahiko Fujii

IPC分类号： B41J2/01 ,  B41J2/015

CPC分类号： B41M5/52 ,  B41J2/0057 ,  B41M2205/12

摘要： A pattern forming process and a pattern forming apparatus comprising forming a liquid receptive particle layer on an intermediate transfer body in a specified area by using liquid receptive particles capable of receiving a recording liquid containing a recording material; applying a liquid droplet of the recording liquid on a specified position of liquid receptive particle layer according to specified data, trapping the recording material near the surface of the liquid receptive particle layer on the intermediate transfer body, and forming a pattern of the recording material near the surface of the liquid receptive particle layer; and removing the liquid receptive particle layer provided with the recording liquid from the intermediate transfer body so that the pattern may be positioned between the transfer object and the liquid receptive particle layer, and transferring the liquid receptive particle layer to the transfer object.

摘要翻译： 图案形成方法和图案形成装置，包括通过使用能够接收含有记录材料的记录液体的液体接收颗粒在特定区域中在中间转印体上形成液体接收颗粒层; 根据规定的数据将记录液体的液滴施加在液体接收颗粒层的指定位置上，将记录材料捕获在中间转印体上的液体接收颗粒层的表面附近，并且在记录材料的附近形成图案 液体接受颗粒层的表面; 以及从中间转印体除去设置有记录液体的液体接收颗粒层，使得图案可以位于转印体和受液颗粒层之间，并将液体接受性颗粒层转印到转印体上。

公开(公告)号：US07810897B2

公开(公告)日：2010-10-12

申请号：US11704594

申请日：2007-02-09

申请人： Arichika Tanaka ,  Hiroaki Satoh ,  Masahiko Sekimoto ,  Satoshi Mohri ,  Toru Nishida

发明人： Arichika Tanaka ,  Hiroaki Satoh ,  Masahiko Sekimoto ,  Satoshi Mohri ,  Toru Nishida

IPC分类号： B41J2/015

CPC分类号： B41J2/0057 ,  B41J11/007 ,  B41J29/17

摘要： A droplet ejection apparatus includes: a droplet ejection head that ejects droplets; a conveying member that retains a recording medium and conveys the recording medium with facing the recording medium to the droplet ejection head; a coating member that coats the conveying member with a lubricant; and a cleaning member that cleans the conveying member. The droplet ejection apparatus satisfies the following formulae (1) L2≧L1  (1) wherein, in the formulae (1): L1 is the width, in the direction orthogonal to the conveying direction, of the cleaning of the conveying member by the cleaning member; and L2 is the width, in the direction orthogonal to the conveying direction, of coating the lubricant on the conveying member by the coating member.

摘要翻译： 液滴喷射装置包括：喷射液滴的液滴喷射头; 输送构件，其保持记录介质并将记录介质面向记录介质传送到液滴喷射头; 用润滑剂涂覆所述输送部件的涂布部件; 以及清洁输送构件的清洁构件。 液滴喷射装置满足下列公式（1）L2≥L1（1）其中，在公式（1）中：L1是与传送方向正交的方向上的清洁通过清洁的传送部件的宽度 会员; L2是在与输送方向正交的方向上通过涂布部件将润滑剂涂布在输送部件上的宽度。

公开(公告)号：US20100165027A1

公开(公告)日：2010-07-01

申请号：US12469772

申请日：2009-05-21

申请人： Takeshi Zengo ,  Susumu Kibayashi ,  Toru Nishida ,  Hiroaki Satoh

发明人： Takeshi Zengo ,  Susumu Kibayashi ,  Toru Nishida ,  Hiroaki Satoh

IPC分类号： B41J29/38

CPC分类号： B41J29/38 ,  B41J11/008 ,  B41J13/223

摘要： The present invention provides an image forming apparatus including: a rotating body that holds recording medias on a circumferential surface; an image forming section that forms an image; a generating section that generates a pulse and a reference pulse; a measuring section that measures the number of pulses; a computing section that each time when predetermined number of pulses from generation of the reference pulse has been measured, divides a pulse width of a pulse before predetermined number of pulses by a first value to compute a pulse division time; and a controlling section that each time when predetermined number of pulses are measured from generation of the reference pulse, multiplies the pulse division time by a second predetermined value, thereby obtaining a forming start time, and that controls to start image formation when the forming start time has elapsed from the measurement of predetermined number of pulses.

摘要翻译： 本发明提供一种图像形成装置，包括：旋转体，其将记录介质保持在周面上; 形成图像的图像形成部; 产生脉冲和参考脉冲的发生部分; 测量部分，测量脉冲数; 每当测量出来自基准脉冲的预定脉冲数时，计算部分将预定脉冲数之前的脉冲的脉冲宽度除以第一值以计算脉冲分割时间; 以及控制部，每当从参考脉冲的产生测量预定数量的脉冲时，将脉冲分割时间乘以第二预定值，从而获得形成开始时间，并且当成形开始时控制开始图像形成 从预定脉冲数的测量开始经过时间。

公开(公告)号：US20070257963A1

公开(公告)日：2007-11-08

申请号：US11703586

申请日：2007-02-07

申请人： Arichika Tanaka ,  Hiroaki Satoh ,  Masahiko Sekimoto ,  Satoshi Mohri ,  Toru Nishida

发明人： Arichika Tanaka ,  Hiroaki Satoh ,  Masahiko Sekimoto ,  Satoshi Mohri ,  Toru Nishida

IPC分类号： B41J2/145

CPC分类号： B41J2/0057 ,  B41J11/007 ,  B41J29/17

摘要： A droplet ejection apparatus includes: a droplet ejection head that ejects droplets; a conveying member that retains a recording medium and conveys the recording medium with facing the recording medium to the droplet ejection head; a coating member that coats the conveying member with a coating liquid having a repellant property to the liquid ejected from the droplet ejection head; and a cleaning member that cleans the conveying member. The droplet ejection apparatus satisfies the following formulae L3≧L1, L2≧L1   (1) wherein, in a direction orthogonal to the conveying direction; L1 is the width of ink droplet ejecting of the droplet ejection head; L2 is the width of coating the coating liquid on the conveying member by the coating member; and L3 is the width of the cleaning of the conveying member by the cleaning member.

摘要翻译： 液滴喷射装置包括：喷射液滴的液滴喷射头; 输送构件，其保持记录介质并将记录介质面向记录介质传送到液滴喷射头; 涂覆部件，其具有对从所述液滴喷射头喷射的液体具有排斥性的涂布液; 以及清洁输送构件的清洁构件。 液滴喷射装置满足下列公式<？in-line-formula description =“In-line formula”end =“lead”？> L3> = L1，L2> = L1（1）<？ =“在线公式”end =“tail”？>其中，在与传送方向正交的方向上; L1是液滴喷射头的墨滴喷射的宽度; L2是通过涂覆部件涂覆在输送部件上的涂布液的宽度; L3是清洁部件清洁输送部件的宽度。

公开(公告)号：US20070257955A1

公开(公告)日：2007-11-08

申请号：US11704594

申请日：2007-02-09

申请人： Arichika Tanaka ,  Hiroaki Satoh ,  Masahiko Sekimoto ,  Satoshi Mohri ,  Toru Nishida

发明人： Arichika Tanaka ,  Hiroaki Satoh ,  Masahiko Sekimoto ,  Satoshi Mohri ,  Toru Nishida

IPC分类号： B41J2/015 ,  B41J2/165

CPC分类号： B41J2/0057 ,  B41J11/007 ,  B41J29/17

摘要： A droplet ejection apparatus includes: a droplet ejection head that ejects droplets; a conveying member that retains a recording medium and conveys the recording medium with facing the recording medium to the droplet ejection head; a coating member that coats the conveying member with a lubricant; and a cleaning member that cleans the conveying member. The droplet ejection apparatus satisfies the following formulae (1) L2≧L1   (1) wherein, in the formulae (1): L1 is the width, in the direction orthogonal to the conveying direction, of the cleaning of the conveying member by the cleaning member; and L2 is the width, in the direction orthogonal to the conveying direction, of coating the lubricant on the conveying member by the coating member.

摘要翻译： 液滴喷射装置包括：喷射液滴的液滴喷射头; 输送构件，其保持记录介质并将记录介质面向记录介质传送到液滴喷射头; 用润滑剂涂覆所述输送部件的涂布部件; 以及清洁输送构件的清洁构件。 液滴喷射装置满足下列公式（1）<？in-line-formula description =“In-line formula”end =“lead”？> L 2> = L 1（1）<？ 其中，在公式（1）中：L 1是与传送方向正交的方向上的清洁部件清洁传送部件的宽度; L2是在与输送方向正交的方向上通过涂布部件将润滑剂涂布在输送部件上的宽度。

公开(公告)号：US20060209153A1

公开(公告)日：2006-09-21

申请号：US11203874

申请日：2005-08-15

申请人： Toru Nishida ,  Hiroaki Satoh ,  Akira Mihara ,  Kiyoshi Hosoi ,  Satoshi Mohri ,  Toyoji Ushioda ,  Takeshi Zengo ,  Koichi Saitoh

发明人： Toru Nishida ,  Hiroaki Satoh ,  Akira Mihara ,  Kiyoshi Hosoi ,  Satoshi Mohri ,  Toyoji Ushioda ,  Takeshi Zengo ,  Koichi Saitoh

IPC分类号： B41J2/205

CPC分类号： B41J13/0045 ,  B41J3/60 ,  B41J11/007

摘要： An image recording apparatus is disclosed wherein an image is recorded on a recording medium based on image information by ejecting liquid droplets from a liquid droplet ejecting head. A liquid droplet ejecting head is provided which has an ejection region substantially corresponding to a width of the recording medium. A conveyor unit is provided which conveys the recording medium to the ejection region of the liquid droplet ejecting head with the recording medium attracted and attached thereto and supported thereon. The recording medium is fed from the conveyor unit to a paper discharge section. Further, a plurality of attracting and supporting sub-units are provided which are vertically moved with the recording medium, which is delivered thereto from the conveyor unit, attracted and attached thereto and supported thereon, thereby conveying the recording medium to a subsequent step.