公开(公告)号：US07830521B2

公开(公告)日：2010-11-09

申请号：US11864711

申请日：2007-09-28

申请人： Hiroaki Yamamoto ,  Toshihito Kimura ,  Hitoshi Shimizu ,  Masashi Hakamata

发明人： Hiroaki Yamamoto ,  Toshihito Kimura ,  Hitoshi Shimizu ,  Masashi Hakamata

IPC分类号： G01N21/00

CPC分类号： G01N21/553 ,  G01N2021/157

摘要： Provided are a detection apparatus, a detection method and an optically transparent member, which can detect a decrease in a precision. A convolution is performed by a convolution portion 80 contained in an image processing portion 38, to acquire the distribution information indicating the light intensity distribution of a light beam, which is totally reflected at the interface and which is incident at a plurality of angles to an dielectric block 52 so as to be totally reflected at the interface of the dielectric block 52. A spatial frequency resolution is performed on the light intensity distribution indicated by the distribution information acquired, by a detection precision evaluating portion 86 contained in the image processing portion 38, to thereby derive the light intensity distribution of each spatial frequency of the light beam. The precision is detected by comparing the light intensity distribution derived, with a threshold value predetermined for each spatial frequency.

摘要翻译： 提供了能够检测精度降低的检测装置，检测方法和光学透明构件。 通过包含在图像处理部分38中的卷积部分80执行卷积，以获取指示在该界面处被全反射并以多个角度入射的光束的光强度分布的分布信息 介质块52，以便在介质块52的界面处被全反射。通过由图像处理部分38中包含的检测精度评估部分86对由所获取的分布信息指示的光强度分布执行空间频率分辨率 ，从而导出光束的每个空间频率的光强度分布。 通过将导出的光强度分布与针对每个空间频率预定的阈值进行比较来检测精度。

公开(公告)号：US20070172891A1

公开(公告)日：2007-07-26

申请号：US11656945

申请日：2007-01-24

申请人： Toshihito Kimura ,  Hisashi Ohtsuka ,  Hiroaki Yamamoto

发明人： Toshihito Kimura ,  Hisashi Ohtsuka ,  Hiroaki Yamamoto

IPC分类号： G01N33/53 ,  G06F19/00

CPC分类号： G01N33/54373 ,  B01L3/502 ,  G01N35/00594

摘要： Reference data are subtracted from corresponding actual measurement data, and unprocessed binding quantity data, each of which represents a quantity of binding of a ligand and each of analytes, are thereby acquired. Calculation is made to find a relationship between the reference data and the unprocessed binding quantity data acquired in cases where the binding does not occur. In accordance with the relationship, variation components, which are contained in the unprocessed binding quantity data, are calculated. The variation components are subtracted from the corresponding unprocessed binding quantity data, and processed binding quantity data are thereby acquired. The processed binding quantity data are utilized for extracting an analyte capable of binding with the ligand.

摘要翻译： 从相应的实际测量数据中减去参考数据，从而获得每个表示配体和每种分析物的结合量的未处理的结合量数据。 进行计算，以在不发生绑定的情况下找到参考数据与未处理的绑定量数据之间的关系。 根据该关系，计算包含在未处理的装订量数据中的变化成分。 从相应的未处理的装订量数据中减去变化分量，从而获得处理的装订量数据。 处理的结合量数据用于提取能够与配体结合的分析物。

公开(公告)号：US07885769B2

公开(公告)日：2011-02-08

申请号：US11656945

申请日：2007-01-24

申请人： Toshihito Kimura ,  Hisashi Ohtsuka ,  Hiroaki Yamamoto

发明人： Toshihito Kimura ,  Hisashi Ohtsuka ,  Hiroaki Yamamoto

IPC分类号： G01N33/48

CPC分类号： G01N33/54373 ,  B01L3/502 ,  G01N35/00594

摘要： Reference data are subtracted from corresponding actual measurement data, and unprocessed binding quantity data, each of which represents a quantity of binding of a ligand and each of analytes, are thereby acquired. Calculation is made to find a relationship between the reference data and the unprocessed binding quantity data acquired in cases where the binding does not occur. In accordance with the relationship, variation components, which are contained in the unprocessed binding quantity data, are calculated. The variation components are subtracted from the corresponding unprocessed binding quantity data, and processed binding quantity data are thereby acquired. The processed binding quantity data are utilized for extracting an analyte capable of binding with the ligand.

摘要翻译： 从相应的实际测量数据中减去参考数据，从而获得每个表示配体和各分析物的结合量的未处理的结合量数据。 进行计算，以在不发生绑定的情况下找到参考数据与未处理的绑定量数据之间的关系。 根据关系，计算包含在未处理的装订量数据中的变化分量。 从相应的未处理的装订量数据中减去变化分量，从而获得处理的装订量数据。 处理的结合量数据用于提取能够与配体结合的分析物。

公开(公告)号：US08410456B2

公开(公告)日：2013-04-02

申请号：US12886985

申请日：2010-09-21

申请人： Hiroaki Yamamoto ,  Yu Tojo ,  Hitoshi Shimizu

发明人： Hiroaki Yamamoto ,  Yu Tojo ,  Hitoshi Shimizu

IPC分类号： G01J1/58

CPC分类号： G01N21/6456 ,  A61B5/0073 ,  G01N21/4795 ,  G01N21/6428 ,  G01N2021/1787

摘要： A measurement data correction method is provided. A living organism is employed as a test sample, fluorescent light generated by excitation light from a fluorescent substance administered to the test sample is received by a light receiving component at a plurality of locations around the periphery of the test sample in a flat plane passing through an observation site of the test sample, and the method is employed for reconstruction of an optical tomographic image of the test sample along the flat plane passing through the observation site. The method includes: generating corrected measurement data, as measurement data to be used in reconstruction of an optical tomographic image along the flat plane passing through the observation site of the test sample, from an obtained first measurement data and an obtained first standardization measurement data using a defined correction coefficient.

摘要翻译： 提供测量数据校正方法。 使用生物体作为测试样品，由施用于测试样品的荧光物质的激发光产生的荧光被测试样品周围的多个位置处的光接收部件在通过的平面内被接收 测试样本的观察部位，并且该方法用于沿着穿过观察部位的平面重建测试样品的光学断层图像。 该方法包括：根据获得的第一测量数据和所获得的第一标准化测量数据，生成校正的测量数据，作为用于沿着穿过测试样本的观察部位的平面的光学断层图像重建中使用的测量数据，使用 定义的校正系数。

公开(公告)号：US20110077888A1

公开(公告)日：2011-03-31

申请号：US12886985

申请日：2010-09-21

申请人： Hiroaki Yamamoto ,  Yu Tojo ,  Hitoshi Shimizu

发明人： Hiroaki Yamamoto ,  Yu Tojo ,  Hitoshi Shimizu

IPC分类号： G06F19/00

CPC分类号： G01N21/6456 ,  A61B5/0073 ,  G01N21/4795 ,  G01N21/6428 ,  G01N2021/1787

摘要： A measurement data correction method is provided. A living organism is employed as a test sample, fluorescent light generated by excitation light from a fluorescent substance administered to the test sample is received by a light receiving component at a plurality of locations around the periphery of the test sample in a flat plane passing through an observation site of the test sample, and the method is employed for reconstruction of an optical tomographic image of the test sample along the flat plane passing through the observation site. The method includes: generating corrected measurement data, as measurement data to be used in reconstruction of an optical tomographic image along the flat plane passing through the observation site of the test sample, from an obtained first measurement data and an obtained first standardization measurement data using a defined correction coefficient.

摘要翻译： 提供测量数据校正方法。 使用生物体作为测试样品，由施用于测试样品的荧光物质的激发光产生的荧光被测试样品周围的多个位置处的光接收部件在通过的平面内被接收 测试样本的观察部位，并且该方法用于沿着穿过观察部位的平面重建测试样品的光学断层图像。 该方法包括：根据获得的第一测量数据和所获得的第一标准化测量数据，生成校正的测量数据，作为用于沿着穿过测试样本的观察部位的平面的光学断层图像的重建中使用的测量数据，使用 定义的校正系数。

公开(公告)号：US09456738B2

公开(公告)日：2016-10-04

申请号：US13283407

申请日：2011-10-27

申请人： Hiroaki Yamamoto

发明人： Hiroaki Yamamoto

IPC分类号： A61B6/00 ,  A61B1/04 ,  A61B1/06 ,  A61B5/1455 ,  A61B1/07

CPC分类号： A61B1/043 ,  A61B1/063 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/0653 ,  A61B1/07 ,  A61B5/14551

摘要： An endoscopic diagnosis system includes a first narrowband light source for emitting first narrowband light having a given wavelength range, a second narrowband light source for emitting second narrowband light having a wavelength range different from that of the first narrowband light, a first image sensor for receiving reflected light of the first narrowband light illuminating a subject from the subject to acquire a narrowband light image in a narrowband light observation mode, a second image sensor for receiving first autofluorescence emitted from the subject as the first narrowband light illuminates the subject to acquire a first autofluorescence image in a first autofluorescence observation mode and receiving second autofluorescence emitted from the subject as the second narrowband light illuminates the subject to acquire a second autofluorescence image in a second autofluorescence observation mode.

摘要翻译： 内窥镜诊断系统包括用于发射具有给定波长范围的第一窄带光的第一窄带光源，用于发射具有与第一窄带光不同的波长范围的第二窄带光的第二窄带光源，用于接收的第一图像传感器 第一窄带光从被摄体照射被摄体的反射光，以获取窄带光观察模式中的窄带光图像;第二图像传感器，用于当第一窄带光照射对象时，从被检体发射的第一自发荧光发光，以获得第一 第一自发荧光观察模式中的自发荧光图像，并且当第二窄带光照射对象以在第二自发荧光观察模式中获取第二自发荧光图像时，接收从对象发射的第二自发荧光。

公开(公告)号：US08915844B2

公开(公告)日：2014-12-23

申请号：US13596867

申请日：2012-08-28

申请人： Hiroaki Yamamoto

发明人： Hiroaki Yamamoto

IPC分类号： A61B1/06 ,  A61B1/04 ,  A61B1/05 ,  A61B1/00

CPC分类号： A61B1/043 ,  A61B1/00006 ,  A61B1/00009 ,  A61B1/05 ,  A61B1/063 ,  A61B1/0638 ,  A61B1/0653

摘要： The endoscope diagnostic apparatus includes a light source emitting white light and two or more kinds of excited light with different center wavelengths for emitting two or more kinds of self-fluorescence from a self-fluorescent material, an imaging unit which receives reflected light of white light to image a normal light image, and receives self-fluorescence emitted from the self-fluorescent material to image self-fluorescent images, and a light source control unit which has compensation coefficients for preventing emission intensity from being lowered depending on the volume of blood when the two or more kinds of excited light are absorbed by blood, and compensates the ratios of emission intensity of the two or more kinds of excited light using the calculated compensation coefficients so as to exclude the influence of absorption of light by blood in each of the two or more kinds of excited light.

摘要翻译： 内窥镜诊断装置包括：发出白光的光源和具有不同中心波长的两种以上的激发光，用于从自发荧光材料发射两种或更多种自发荧光;成像单元，其接收白光的反射光 对正常的光图像进行成像，并且接收从自身荧光材料发射的自体荧光以图像自发荧光图像;以及光源控制单元，其具有用于防止发射强度根据血液体积而降低的补偿系数 两种或更多种激发光被血液吸收，并且使用所计算的补偿系数来补偿两种或更多种激发光的发射强度的比率，以便排除在每个激光的每一个中由血液吸收光的影响 两种或多种激发光。

公开(公告)号：US08836983B2

公开(公告)日：2014-09-16

申请号：US13558766

申请日：2012-07-26

申请人： Hiroaki Yamamoto ,  Jyunya Yamada ,  Tadashi Hata ,  Toshiharu Hayashida

发明人： Hiroaki Yamamoto ,  Jyunya Yamada ,  Tadashi Hata ,  Toshiharu Hayashida

IPC分类号： G06F3/12

CPC分类号： G06F9/4401

摘要： An information processing device includes an execution unit that executes a control program for causing a functional unit to realize a predetermined function, a memory that stores the control program, a state variable indicating a state of the functional unit, and activation history of either initial activation or second and following activation, in a nonvolatile memory, and a communication unit that causes the execution unit to communicate with the functional unit, wherein the execution unit includes a first procedure where the control program is stored in the memory and the control program is read and is executed, and a second procedure where the control program pre-stored in the memory is read and is executed, refers to the activation history when activation is performed, executes the first procedure in a case of the initial activation, and executes the second procedure in a case of the second and following activation.

摘要翻译： 信息处理装置包括：执行单元，执行用于使功能单元实现预定功能的控制程序，存储控制程序的存储器，指示功能单元的状态的状态变量，以及初始激活的激活历史 或第二次和之后的激活，以及使执行单元与功能单元通信的通信单元，其中执行单元包括第一过程，其中控制程序存储在存储器中并且读取控制程序 并且执行预先存储在存储器中的控制程序被读取并被执行的第二过程，参考执行激活时的激活历史，在初始激活的情况下执行第一过程，并且执行第二过程 在第二次和之后激活的情况下的程序。

公开(公告)号：US20120324182A1

公开(公告)日：2012-12-20

申请号：US13582185

申请日：2010-12-10

申请人： Hiroaki Yamamoto ,  Takatoshi Sato ,  Masanori Tsuda

发明人： Hiroaki Yamamoto ,  Takatoshi Sato ,  Masanori Tsuda

IPC分类号： G06F12/16

CPC分类号： G06F3/0641 ,  G06F3/0608 ,  G06F3/0689

摘要： A storage device 110 includes: a data writing part 111 configured to store data to be written into a storage device 120 and also, when storing other data of the same content as the data already stored in the storage device into the storage device, refer to the data already stored in the storage device as the other data; and a data separating part 112 configured to separate data to be written into a user data portion and a management data portion that are classified in accordance with a previously set criterion. The data writing part 111 is configured to store the user data portion into a user data file 121, store the management data portion into a management data file 122, and store the user data portion and the management data portion separated by the data separating part 112 into the storage device 120.

摘要翻译： 存储装置110包括：数据写入部111，被配置为存储要写入存储装置120的数据，并且当将与存储在存储装置中的数据相同的内容的其他数据存储到存储装置中时，参考 已经存储在存储设备中的数据作为其他数据; 以及数据分离部分112，被配置为将要写入的用户数据部分的数据和根据先前设定的标准分类的管理数据部分分离。 数据写入部分111被配置为将用户数据部分存储到用户数据文件121中，将管理数据部分存储到管理数据文件122中，并存储由数据分离部分112分隔的用户数据部分和管理数据部分 进入存储装置120。

公开(公告)号：US08061083B2

公开(公告)日：2011-11-22

申请号：US12360469

申请日：2009-01-27

申请人： Nakatsune Shirai ,  Hidenori Ishihara ,  Tomoki Yamashita ,  Hiroaki Yamamoto ,  Katsumi Endo

发明人： Nakatsune Shirai ,  Hidenori Ishihara ,  Tomoki Yamashita ,  Hiroaki Yamamoto ,  Katsumi Endo

IPC分类号： E05F11/38

CPC分类号： E05F15/697 ,  E05F11/445 ,  E05Y2800/422 ,  E05Y2900/55

摘要： A drive apparatus for opening and closing a window glass provided in a door having an inner panel is disclosed. The drive apparatus includes a motor provided in the door and a regulator that receives drive force from the motor and selectively open and close the window glass. The door noise includes motor operating noise and vibration transmission noise that is generated when vibration of the motor is transmitted to the inner panel via the regulator. The motor is configured such that a first-order frequency component in vibration of the motor is greater than any other nth component (n is an integer greater than or equal to two), so that the first-order frequency component in the door noise is greater than any other nth frequency component (n is an integer greater than or equal to two).

摘要翻译： 公开了一种用于打开和关闭设置在具有内板的门中的窗玻璃的驱动装置。 驱动装置包括设置在门中的马达和调节器，其接收来自马达的驱动力并选择性地打开和关闭窗玻璃。 门噪声包括电动机运行噪声和当电动机的振动经由调节器传递到内板时产生的振动传播噪声。 电动机被构造成使得电动机的振动中的一阶频率分量大于任何其他第n个分量（n是大于或等于2的整数），使得门噪声中的一阶频率分量为 大于任何其他第n个频率分量（n是大于或等于2的整数）。