摘要:
A novel protein involved in cell-death and a gene encoding the protein, the use thereof to screen for an anti-cell-death factor for use in the treatment of a disorder caused by excessive cell-death or to screen for a remedy for a disorder caused by aberrant suppression of cell-death, and the screening method are provided. Human HtrA2 and human HtrA2-expressing cells and animals to screen for an anti-cell-death factor for use in the treatment of a disorder caused by excessive cell-death, a method for screening for an anti-cell-death factor for use in the treatment of disorder caused by excessive cell-death, and a method for screening for a remedy for a disorder caused by aberrant suppression of cell-death.
摘要:
The present invention found the interaction of CREBL1 and HNF-4α with HtrA2 and revealed for the first time that CREBL1, ATF6, and HNF-4α are degraded by active HtrA2. In addition, the present invention provides a means for inhibiting the degradation of at least one of CREBL1, ATF6, and HNF-4α, comprising inhibiting the function of HtrA2; a means for preventing and/or treating diabetes, comprising inhibiting the degradation by HtrA2 of at least one of CREBL1, ATF6, and HNF-4α; a means for preventing cell death (for example, pancreatic β cell death), comprising inhibiting the degradation by HtrA2 of CREBL1 and/or ATF6; a means for preventing and/or treating type 2 diabetes, comprising inhibiting the degradation by HtrA2 of HNF-4α; and a reagent kit.
摘要:
A communication apparatus is configured to communicate with a service providing server. The service providing server provides a data upload service and, for each user, associate and stores authentication information for a user and an e-mail address for the user. The communication apparatus includes: a storage control unit storing specific authentication information for a specific user in a memory; an acquisition unit which, when an upload instruction for uploading target data to the service providing server is input from the specific user, uses the specific authentication information in the memory to acquire a specific e-mail address, which is stored in association with the specific authentication information, from the service providing server; and an upload unit that transmits a specific e-mail including the target data and the specific e-mail address as a transmission destination address, for uploading the target data to the service providing server.
摘要:
A power domain is automatically generated.A computer performs a function simulation process 9 for evaluating whether or not a designed circuit satisfies a specification, and a clustering process 10 which obtains a power domain by clustering logical blocks in which activation timings are within a range, based on the result of the function simulation process. Since the power domain is obtained by a process performed by the computer, the power domain can be optimized compared to a case when it is obtained by hand (manual work of the designer).
摘要:
The present invention relates to a routing analysis method for performing a routing analysis on an integrated circuit from a netlist which is information on a plurality of cells constituting the integrated circuit and routes connecting the cells, and the routing analysis method comprises a step (Step 1) of obtaining the sum of areas of a plurality of cells, the number of cells or the number of routes connecting the cells from the netlist, to be defined as a constant C, and calculating a layout area S which is an area of a square layout region, by dividing the constant C by a predetermined constant U, a step (Step 2) of calculating a total route length L by multiplying a half perimeter length H of the layout region having the layout area S obtained in Step 1 by a predetermined coefficient α, and a step (Step 3) of calculating a routing difficulty index by dividing the total route length L by the layout area S. Thus, the present invention provides a routing analysis method for an integrated circuit, which, allows calculation of routing difficulty index with high accuracy of prediction.
摘要:
An information processing device may comprise a log file creating unit and a first storage controlling unit. The log file creating unit may be configured to create, each time information is input, one log file that includes log information indicating an input of the information. The storage controlling unit may be configured to store, each time the one log file is created, the one log file in a storage area.
摘要:
The present invention relates to a routing analysis method for performing a routing analysis on an integrated circuit from a netlist which is information on a plurality of cells constituting the integrated circuit and routes connecting the cells, and the routing analysis method comprises a step (Step 1) of obtaining the sum of areas of a plurality of cells, the number of cells or the number of routes connecting the cells from the netlist, to be defined as a constant C, and calculating a layout area S which is an area of a square layout region, by dividing the constant C by a predetermined constant U, a step (Step 2) of calculating a total route length L by multiplying a half perimeter length H of the layout region having the layout area S obtained in Step 1 by a predetermined coefficient α, and a step (Step 3) of calculating a routing difficulty index by dividing the total route length L by the layout area S. Thus, the present invention provides a routing analysis method for an integrated circuit, which, allows calculation of routing difficulty index with high accuracy of prediction.
摘要:
A method and composition for polymer-reinforced composite cementitious construction materials is described. In one embodiment, a crosslinking component is mixed with a high molecular weight strengthening component and an inorganic cementitious material. The addition of the mixture to water causes a crosslinked molecular network to form within the hydrated, composite cementitious construction material. Both enhanced flexural strength and improved nail-pull resistance are shown, allowing a reduction in weight of the composite cementitious construction material compared to cementitious construction materials made according to other known methods.
摘要:
An inorganic-organic composite comprises an inorganic phase, such as gypsum crystals, and a film forming organic phase. The film forming organic phase is selected from substituted starches having a degree of polymerization; degree of substitution and viscosity such that the substituted starches are insoluble in water during mixing but dissolve at a higher processing temperature during forming, setting or drying of the composite. Thus, excessive migration of the substitute starch is prevented and the composite is substantially strengthened.
摘要:
The present invention relates to a routing analysis method for performing a routing analysis on an integrated circuit from a netlist which is information on a plurality of cells constituting the integrated circuit and routes connecting the cells, and the routing analysis method comprises a step (Step 1) of obtaining the sum of areas of a plurality of cells, the number of cells or the number of routes connecting the cells from the netlist, to be defined as a constant C, and calculating a layout area S which is an area of a square layout region, by dividing the constant C by a predetermined constant U, a step (Step 2) of calculating a total route length L by multiplying a half perimeter length H of the layout region having the layout area S obtained in Step 1 by a predetermined coefficient α, and a step (Step 3) of calculating a routing difficulty index by dividing the total route length L by the layout area S. Thus, the present invention provides a routing analysis method for an integrated circuit, which, allows calculation of routing difficulty index with high accuracy of prediction.