公开(公告)号：US20100120139A1

公开(公告)日：2010-05-13

申请号：US12530555

申请日：2008-03-10

申请人： Hiroki Busujima ,  Atsushi Nakao

发明人： Hiroki Busujima ,  Atsushi Nakao

IPC分类号： C12M1/00

CPC分类号： C12M41/34 ,  C12M41/14

摘要： An incubation apparatus is provided to incubate culture targets such as cells, embryos or microorganisms in an incubation chamber. The incubation apparatus is capable of inexpensively, highly accurately and automatically calibrating a gas concentration sensor. The incubation apparatus includes a gas concentration sensor 42 which detects a gas concentration in the incubation chamber 4, control means (controller 70) for controlling the supply of a gas into the incubation chamber on the basis of an output of the gas concentration sensor 42, and standard gas supply means for supplying the gas concentration sensor 42 with a standard gas which has been previously adjusted to an actually used gas concentration or a gas concentration close thereto. The control means (controller 70) maintains the concentration of the standard gas, supplies the standard gas to the gas concentration sensor 42 by the standard gas supply means, and on the basis of an output of the gas concentration sensor 42 and the concentration of the standard gas at the moment, calibrates the actually used gas concentration of the gas concentration sensor 42.

摘要翻译： 提供孵育装置以在孵育室中培养诸如细胞，胚胎或微生物的培养物目标。 培养装置能够廉价，高精度地自动校准气体浓度传感器。 培养装置包括检测培养室4内的气体浓度的气体浓度传感器42，控制装置（控制器70），其根据气体浓度传感器42的输出控制向培养室供给气体， 以及标准气体供给装置，用于向气体浓度传感器42供应预先调节为实际使用的气体浓度或接近其的气体浓度的标准气体。 控制装置（控制器70）保持标准气体的浓度，通过标准气体供给装置向气体浓度传感器42提供标准气体，并且基于气体浓度传感器42的输出和浓度 此时的标准气体，校准气体浓度传感器42的实际使用的气体浓度。

公开(公告)号：US20120273047A1

公开(公告)日：2012-11-01

申请号：US13457675

申请日：2012-04-27

申请人： Yasuhiko Yokoi ,  Koichi Kobayashi ,  Hiroshi Yamamoto ,  Hiroki Busujima

发明人： Yasuhiko Yokoi ,  Koichi Kobayashi ,  Hiroshi Yamamoto ,  Hiroki Busujima

IPC分类号： F17D3/00 ,  C12M1/00

CPC分类号： C12M23/44 ,  A61L2/208 ,  B01L1/025 ,  C12M41/14 ,  Y10T137/0318

摘要： An isolator capable of having a culture apparatus demountably mounted thereto, the isolator includes: a working chamber; a storage chamber; a first opening configured to allow a culture chamber of the culture apparatus and the working chamber to communicate with each other, when the culture apparatus has been mounted; a second opening configured to allow the working chamber and the storage chamber to communicate with each other; a first door configured to close the second opening so as to hermetically seal the storage chamber; and a temperature adjusting device configured to, when culture taken out of the culture chamber has been stored in the storage chamber, and the storage chamber has been hermetically sealed, and thereafter the culture apparatus has been demounted, adjust temperature of the culture stored in the storage chamber.

摘要翻译： 一种能够具有可拆卸地安装在其上的培养装置的隔离器，所述隔离器包括：工作室; 储存室; 当培养装置已被安装时，构造成允许培养装置的培养室和工作室相互连通的第一开口; 第二开口，其构造成允许所述工作室和所述储存室彼此连通; 第一门，其构造成关闭所述第二开口以密封所述储存室; 以及温度调节装置，其被配置为当从所述培养室取出的培养物已被储存在所述储存室中并且所述储存室已被气密密封时，并且其后所述培养装置已经被拆除，则调节所述培养室中储存的培养物的温度 储存室。

公开(公告)号：US20120264201A1

公开(公告)日：2012-10-18

申请号：US13527027

申请日：2012-06-19

申请人： Kuniyoshi Kobayashi ,  Hiroki Busujima ,  Yasuhiro Kikuchi ,  Yuichi Tamaoki ,  Shinji Sugimoto ,  Tetsuo Sakurai

发明人： Kuniyoshi Kobayashi ,  Hiroki Busujima ,  Yasuhiro Kikuchi ,  Yuichi Tamaoki ,  Shinji Sugimoto ,  Tetsuo Sakurai

IPC分类号： C12M1/34

CPC分类号： C12M41/14 ,  C12M23/48 ,  C12M37/00 ,  Y10S435/809

摘要： A culture apparatus comprising: an inner box configured to form a culture chamber; an outer box configured to cover the inner box; a fan configured to circulate gas inside the culture chamber through an air passage provided in the inner box within the culture chamber; a first through hole configured to penetrate a wall configuring a part of the air passage in the inner box; a second through hole configured to penetrate the wall and disposed at a position at which a flow velocity of the gas circulated through the air passage by the fan is lower than a flow velocity of the gas around the first through hole; a connecting pipe configured to connect the first through hole and the second through hole outside of the inner box; and a sensor configured to detect a concentration of the gas flowing in the culture chamber.

摘要翻译： 一种培养装置，包括：内箱，其构造成形成培养室; 外箱，其构造成覆盖所述内箱; 风扇，其构造成通过设置在所述培养室内的内箱内的空气通路使所述培养室内的气体循环; 第一通孔，其构造成穿过构成所述内箱中的所述空气通道的一部分的壁; 第二通孔，被构造成穿透壁并且设置在通过风扇在空气通道中循环的气体的流速低于围绕第一通孔的气体的流速的位置; 连接管，其构造成将所述第一通孔与所述第二通孔连接在所述内箱的外部; 以及传感器，被配置为检测在所述培养室中流动的气体的浓度。

公开(公告)号：US20090227008A1

公开(公告)日：2009-09-10

申请号：US12294157

申请日：2007-03-08

申请人： Hiroki Busujima

发明人： Hiroki Busujima

IPC分类号： C12M1/00

CPC分类号： C12M41/48 ,  A61L2/186 ,  C12M37/00 ,  C12M41/14

摘要： There is provided a culture apparatus which is capable of shortening a sterilization time and sterilizing the culture apparatus including a gas concentration measuring sensor, pipes connected to a gas concentration measuring device and every corner of a cultivating chamber. The culture apparatus includes a sterilizing gas generator 42 that supplies sterilizing gas into a cultivating chamber 4. The sterilizing gas generator 42 atomizes a sterilizer solution (oxygenated water) by means of an ultrasonic vibrator 46. The culture apparatus further includes an ultraviolet generator (ultraviolet lamp 50) that irradiates gas in the cultivating chamber 4 with an ultraviolet ray. The culture apparatus further includes a door (outer door 14) for blocking an opening of the cultivating chamber 4 in a free-opening/closing manner and a locking device 52 for prohibiting the door (outer door 14) from being opened. The culture apparatus further includes a controller 60 for controlling the locking device 52 to prevent the door (outer door 14) from being opened from start of the sterilization process to end of the decomposition process.

摘要翻译： 提供了一种能够缩短灭菌时间并对包括气体浓度测量传感器，连接到气体浓度测量装置的管道和培养室的每个角落的管道进行灭菌的培养装置。 培养装置包括向培养室4供给杀菌气体的杀菌气体发生器42.灭菌气体发生器42通过超声波振子46使灭菌液（含氧水）雾化。培养装置还包括紫外线发生器（紫外线 灯50），其利用紫外线照射培养室4中的气体。 培养装置还包括用于以自由开闭方式封闭培养室4的开口的门（外门14）和用于禁止门（外门14）打开的锁定装置52。 培养装置还包括控制器60，用于控制锁定装置52，以防止门（外门14）从开始灭菌过程开始到分解过程结束。

公开(公告)号：US20090195129A1

公开(公告)日：2009-08-06

申请号：US12307010

申请日：2007-07-03

申请人： Shinji Osawa ,  Hiroki Busujima

发明人： Shinji Osawa ,  Hiroki Busujima

IPC分类号： B01L7/00 ,  A47B81/00

CPC分类号： C12M41/14 ,  A47B57/40 ,  A47B88/43 ,  C12M23/48

摘要： A rack device is provided in which a receiver can be prevented from being separated off from a rack post and an incubator having the rack device is also provided. A rack device 1 in which a receiver 11 is mounted between a pair of rack posts 8 and 9 to hold a rack on the receiver 11 includes a pair of engaging hooks 11C and 11D which are formed in the receiver and a plurality of engaging holes 14 and 18 which are formed in both the rack posts and in which both of the engaging hooks of the receiver disengageably engage, respectively. The rack posts are configured to be able to change an interval therebetween and select a first state in which the engaging hooks can be disengaged from the engaging holes and a second state in which the movement of the receiver is restricted while the engaging hooks be kept to engage in the engaging holes by changing the interval between the rack posts.

摘要翻译： 提供了一种机架装置，其中可以防止接收器与机架柱分离，并且还提供具有齿条装置的培养箱。 其中接收器11安装在一对支架8和9之间以将支架固定在接收器11上的支架装置1包括形成在接收器中的一对接合钩11C和11D以及多个接合孔14 和18，它们分别形成在两个齿条柱中，并且接收器的两个接合钩分别啮合。 齿条柱构造成能够改变它们之间的间隔，并且选择接合钩可以从接合孔脱离的第一状态和接合钩的运动被限制在第二状态，其中接合钩保持在 通过改变支架柱之间的间隔来啮合啮合孔。

公开(公告)号：US08663979B2

公开(公告)日：2014-03-04

申请号：US13527027

申请日：2012-06-19

申请人： Kuniyoshi Kobayashi ,  Hiroki Busujima ,  Yasuhiro Kikuchi ,  Yuichi Tamaoki ,  Shinji Sugimoto ,  Tetsuo Sakurai

发明人： Kuniyoshi Kobayashi ,  Hiroki Busujima ,  Yasuhiro Kikuchi ,  Yuichi Tamaoki ,  Shinji Sugimoto ,  Tetsuo Sakurai

IPC分类号： C12M1/38

CPC分类号： C12M41/14 ,  C12M23/48 ,  C12M37/00 ,  Y10S435/809

摘要： A culture apparatus comprising: an inner box configured to form a culture chamber; an outer box configured to cover the inner box; a fan configured to circulate gas inside the culture chamber through an air passage provided in the inner box within the culture chamber; a first through hole configured to penetrate a wall configuring a part of the air passage in the inner box; a second through hole configured to penetrate the wall and disposed at a position at which a flow velocity of the gas circulated through the air passage by the fan is lower than a flow velocity of the gas around the first through hole; a connecting pipe configured to connect the first through hole and the second through hole outside of the inner box; and a sensor configured to detect a concentration of the gas flowing in the culture chamber.

摘要翻译： 一种培养装置，包括：内箱，其构造成形成培养室; 外箱，其构造成覆盖所述内箱; 风扇，其构造成通过设置在所述培养室内的内箱内的空气通路使所述培养室内的气体循环; 第一通孔，其构造成穿过构成所述内箱中的所述空气通道的一部分的壁; 第二通孔，被构造成穿透壁并且设置在通过风扇在空气通道中循环的气体的流速低于围绕第一通孔的气体的流速的位置; 连接管，其构造成将所述第一通孔与所述第二通孔连接在所述内箱的外部; 以及传感器，被配置为检测在所述培养室中流动的气体的浓度。

公开(公告)号：US08563300B2

公开(公告)日：2013-10-22

申请号：US13241619

申请日：2011-09-23

申请人： Hiroki Busujima ,  Yoshihiro Takahashi

发明人： Hiroki Busujima ,  Yoshihiro Takahashi

IPC分类号： C12M1/00 ,  C12M3/00 ,  A61L2/00 ,  B06B1/00

CPC分类号： C12M41/14 ,  C12M37/00

摘要： An incubator comprising: a culture chamber configured to accommodate culture; a dish structure configured to contain a liquid; an ultrasonic vibrator provided in a part of the dish structure, the ultrasonic vibrator configured to atomize the liquid; and a gas-liquid contact structure configured to bring the atomized liquid into contact with air in the chamber to be cultured.

摘要翻译： 一种培养箱，包括：构造成适应培养的培养室; 配置为容纳液体的盘结构; 超声波振动器，设置在所述碟形结构的一部分中，所述超声波振动器被配置为使所述液体雾化; 以及气液接触结构，其构造成使所述雾化液体与待培养的所述室内的空气接触。

公开(公告)号：US08557572B2

公开(公告)日：2013-10-15

申请号：US13527054

申请日：2012-06-19

申请人： Kuniyoshi Kobayashi ,  Hiroki Busujima ,  Yasuhiro Kikuchi ,  Yuichi Tamaoki ,  Shinji Sugimoto ,  Tetsuo Sakurai

发明人： Kuniyoshi Kobayashi ,  Hiroki Busujima ,  Yasuhiro Kikuchi ,  Yuichi Tamaoki ,  Shinji Sugimoto ,  Tetsuo Sakurai

IPC分类号： C12M1/36 ,  C12M1/12

CPC分类号： C12M41/14 ,  C12M23/48 ,  C12M37/00 ,  Y10S435/809

摘要： A culture apparatus comprising: a fan configured to circulate air inside a culture chamber in a predetermined direction in the culture chamber; a duct configured to guide air circulating inside the culture chamber along a wall face inside the culture chamber from an upper part to a lower part of the culture chamber; and a gas generator detachable from a predetermined position at a lower part of the duct, the gas generator being configured to take in air discharged from a lower part of the duct and discharge together with the air taken in a hydrogen peroxide gas to sterilize the inside of the culture chamber generated from a hydrogen peroxide solution into the culture chamber.

摘要翻译： 一种培养装置，其特征在于，包括：风扇，其构成为使培养室内的空气沿规定方向在培养室内循环; 导管，被配置为沿着培养室内的壁面从培养室的上部向下部引导在培养室内循环的空气; 以及气体发生器，其从所述管道的下部的预定位置可拆卸，所述气体发生器被配置为吸入从所述管道的下部排出的空气并与吸入过氧化氢气体的空气一起排出以对内部进行灭菌 的培养室从过氧化氢溶液生成到培养室中。

公开(公告)号：US20120258528A1

公开(公告)日：2012-10-11

申请号：US13527054

申请日：2012-06-19

申请人： Kuniyoshi Kobayashi ,  Hiroki Busujima ,  Yasuhiro Kikuchi ,  Yuichi Tamaoki ,  Shinji Sugimoto ,  Tetsuo Sakurai

发明人： Kuniyoshi Kobayashi ,  Hiroki Busujima ,  Yasuhiro Kikuchi ,  Yuichi Tamaoki ,  Shinji Sugimoto ,  Tetsuo Sakurai

IPC分类号： C12M1/12

CPC分类号： C12M41/14 ,  C12M23/48 ,  C12M37/00 ,  Y10S435/809

摘要： A culture apparatus comprising: a fan configured to circulate air inside a culture chamber in a predetermined direction in the culture chamber; a duct configured to guide air circulating inside the culture chamber along a wall face inside the culture chamber from an upper part to a lower part of the culture chamber; and a gas generator detachable from a predetermined position at a lower part of the duct, the gas generator being configured to take in air discharged from a lower part of the duct and discharge together with the air taken in a hydrogen peroxide gas to sterilize the inside of the culture chamber generated from a hydrogen peroxide solution into the culture chamber.

摘要翻译： 一种培养装置，其特征在于，包括：风扇，其构成为使培养室内的空气沿规定方向在培养室内循环; 导管，被配置为沿着培养室内的壁面从培养室的上部向下部引导在培养室内循环的空气; 以及气体发生器，其从所述管道的下部的预定位置可拆卸，所述气体发生器被配置为吸入从所述管道的下部排出的空气并与吸入过氧化氢气体的空气一起排出以对内部进行灭菌 的培养室从过氧化氢溶液生成到培养室中。

公开(公告)号：US08227239B2

公开(公告)日：2012-07-24

申请号：US12703532

申请日：2010-02-10

申请人： Hiroki Busujima ,  Yasuhiro Kikuchi ,  Kenichi Ito ,  Kuniyoshi Kobayashi

发明人： Hiroki Busujima ,  Yasuhiro Kikuchi ,  Kenichi Ito ,  Kuniyoshi Kobayashi

IPC分类号： C12M1/36 ,  A61L2/10

CPC分类号： C12M41/14 ,  A61L2/10 ,  C12M37/00 ,  C12M37/06 ,  Y10S435/809

摘要： A culture apparatus comprising: a housing including a culture chamber inside, culture being cultured in the culture chamber; a door configured to seal the culture chamber; an ultraviolet lamp configured to generate an ultraviolet ray for disinfecting air in the culture chamber; a lighting device configured to allow the ultraviolet lamp to be on for a predetermined time period, when the air in the culture chamber is disinfected; a detecting device configured to detect deterioration of disinfection capability of the ultraviolet lamp; and a controller configured to correct the predetermined time period, during which the ultraviolet lamp is on, so as to be longer according to the deterioration of the disinfection capability of the ultraviolet lamp detected by the detecting device.

摘要翻译： 一种培养装置，其特征在于，包括：在培养室内培养的培养室内的培养室， 构造成密封培养室的门; 紫外灯，其构造成产生用于对培养室中的空气进行消毒的紫外线; 照明装置，被配置为当所述培养室中的空气被消毒时允许所述紫外线灯处于预定时间段; 检测装置，其被配置为检测所述紫外线灯的消毒能力的劣化; 以及控制器，其被配置为根据由所述检测装置检测到的所述紫外线灯的消毒能力的劣化来校正所述紫外线灯在其中导通的所述预定时间段。