公开(公告)号：US08731637B2

公开(公告)日：2014-05-20

申请号：US11655318

申请日：2007-01-19

申请人： Hironao Kawano ,  Hironobu Takizawa ,  Akio Uchiyama ,  Atsushi Chiba ,  Takeshi Yokoi ,  Hideo Ito ,  Hidetake Segawa

发明人： Hironao Kawano ,  Hironobu Takizawa ,  Akio Uchiyama ,  Atsushi Chiba ,  Takeshi Yokoi ,  Hideo Ito ,  Hidetake Segawa

IPC分类号： A61B5/05

CPC分类号： A61B1/041 ,  A61B1/00036 ,  A61B1/00158 ,  A61B5/061 ,  A61B5/073 ,  A61B5/4839 ,  A61B5/702 ,  A61B34/73

摘要： Provided is an intra-subject medical system which includes a body-insertable device and a physical quantity generator. The body-insertable device is to be introduced into a subject, is covered by a capsule-shaped exterior member, and includes a physical quantity detecting member which has a directivity to detect a predetermined physical quantity; at least one functional member which has a necessary function for examining or treating inside the subject; and a switch control unit which controls an on/off state or operation mode of the at least one functional member when the physical quantity detecting member detects a physical quantity. The physical quantity generator has a physical quantity emitting unit which emits a temporary physical quantity inside the subject; and a physical quantity direction changing unit which changes an emission direction of the physical quantity.

摘要翻译： 提供了一种主体内医疗系统，其包括身体可插入装置和物理量发生器。 身体插入装置被引入到被检体中，被胶囊形外部构件覆盖，并且包括物理量检测构件，其具有检测预定物理量的方向性; 至少一个具有用于在受试者内检查或治疗的必要功能的功能部件; 以及开关控制单元，其在所述物理量检测构件检测到物理量时控制所述至少一个功能构件的开/关状态或操作模式。 物理量发生器具有在物体内发出临时物理量的物理量发射单元; 以及物理量方向改变单元，其改变物理量的发射方向。

公开(公告)号：US20130184526A1

公开(公告)日：2013-07-18

申请号：US13788621

申请日：2013-03-07

申请人： Hironobu Takizawa ,  Hironao Kawano ,  Akio Uchiyama ,  Shinsuke Tanaka ,  Atsushi Chiba

发明人： Hironobu Takizawa ,  Hironao Kawano ,  Akio Uchiyama ,  Shinsuke Tanaka ,  Atsushi Chiba

IPC分类号： A61B1/00 ,  A61B1/04

CPC分类号： A61B1/00158 ,  A61B1/00082 ,  A61B1/00156 ,  A61B1/041 ,  A61B5/073 ,  A61B5/7232 ,  A61B34/73 ,  A61M31/002

摘要： Using a guidance system with a simple configuration, propulsive motion along a longitudinal direction and changing of the propulsion direction are easily performed with good precision and stability. There is provided a capsule-type medical apparatus which is inserted into the body of a subject and is guided by an external magnetic field, the capsule-type medical apparatus comprising: a substantially cylindrical capsule; a propulsion mechanism for converting rotary motion about a longitudinal axis R of the capsule into propulsive motion along the longitudinal axis R; a magnet accommodated inside the capsule and disposed in such a manner that the magnetic-pole direction thereof can be switched between a direction along the longitudinal axis R and a direction intersecting the longitudinal axis R; and a securing portion for securing the magnet to the capsule in each of the switched states of the magnetic-pole direction.

摘要翻译： 使用简单构造的引导系统，可以容易地以良好的精度和稳定性执行沿纵向的推进运动和推进方向的改变。 提供一种胶囊型医疗装置，其插入到被检体的体内并被外部磁场引导，所述胶囊型医疗装置包括：大致圆柱形的胶囊; 用于将围绕胶囊的纵向轴线R的旋转运动转换成沿着纵向轴线R的推进运动的推进机构; 容纳在胶囊内部的磁体，其设置成使其磁极方向能够沿着纵向轴线R的方向和与纵向轴线R相交的方向转换; 以及用于在磁极方向的每个切换状态下将磁体固定到胶囊的固定部分。

公开(公告)号：US08306592B2

公开(公告)日：2012-11-06

申请号：US11013178

申请日：2004-12-15

申请人： Hironobu Takizawa ,  Hironao Kawano ,  Akio Uchiyama ,  Hidetake Segawa ,  Masatoshi Homan

发明人： Hironobu Takizawa ,  Hironao Kawano ,  Akio Uchiyama ,  Hidetake Segawa ,  Masatoshi Homan

IPC分类号： A61B5/1455

CPC分类号： A61B1/041 ,  A61B1/00016 ,  A61B1/00036 ,  A61B1/05 ,  A61B5/0084 ,  A61B5/073 ,  A61B5/14539 ,  A61B5/14546 ,  A61B2562/245

摘要： A capsule casing of a capsule medical device has a chemical sensor inside, used for sensing operation. The chemical sensor has a recovery device which resets the chemical sensor to an initial state thereof so as to use the chemical sensor for the sensing operation a plurality of times or continuously.

摘要翻译： 胶囊医疗装置的胶囊型壳体内部具有用于检测动作的化学传感器。 化学传感器具有将化学传感器复位到其初始状态的恢复装置，以便多次或连续地使用化学传感器进行感测操作。

公开(公告)号：US20120265015A1

公开(公告)日：2012-10-18

申请号：US13427172

申请日：2012-03-22

申请人： Hironao Kawano ,  Hironobu Takizawa ,  Hidetake Segawa ,  Isao Aoki ,  Katsumi Hirakawa ,  Satomi Kobayashi ,  Hideo Ito

发明人： Hironao Kawano ,  Hironobu Takizawa ,  Hidetake Segawa ,  Isao Aoki ,  Katsumi Hirakawa ,  Satomi Kobayashi ,  Hideo Ito

IPC分类号： A61B1/00

CPC分类号： A61B1/045 ,  A61B1/00016 ,  A61B1/00036 ,  A61B1/00147 ,  A61B1/00156 ,  A61B1/00158 ,  A61B1/041 ,  A61B1/273 ,  A61B5/062 ,  A61B5/073 ,  A61B34/73

摘要： An object of the present invention is to actively control at least one of the position and direction of the imaging field in a subject and to observe a desired observed region in the subject certainly in a short period of time. A body-insertable device system according to the present invention includes a capsule endoscope 1 introduced into a subject and a permanent magnet 3. An imaging unit of the capsule endoscope 1 for taking an image inside the subject is fixed in a casing. The capsule endoscope 1 includes a drive unit for changing at least one of the position and posture of the casing in the liquid 2a which is also introduced in the subject 100. The permanent magnet 3 controls the operation of the drive unit for changing at least one of the position and posture of the casing in the liquid 2a.

摘要翻译： 本发明的一个目的是主动地控制受试者中成像领域的位置和方向中的至少一个，并且在短时间内肯定地观察对象中期望的观察区域。 根据本发明的被检体内导入系统包括被引入到被检体内的胶囊型内窥镜1和永久磁铁3.将胶囊型内窥镜1拍摄于被检体内的图像的摄像部固定在壳体内。 胶囊型内窥镜1包括驱动单元，用于改变也被引入被检体100的液体2a中的壳体的位置和姿势中的至少一个。永久磁铁3控制驱动单元的操作，以改变至少一个 壳体在液体2a中的位置和姿势。

公开(公告)号：US08192346B2

公开(公告)日：2012-06-05

申请号：US12163189

申请日：2008-06-27

申请人： Hironao Kawano ,  Hironobu Takizawa

发明人： Hironao Kawano ,  Hironobu Takizawa

IPC分类号： A61N2/00

CPC分类号： A61B1/2736 ,  A61B1/00158 ,  A61B1/04 ,  A61B1/041

摘要： A housing apparatus includes housing units in which a plurality of permanent magnets are housed, respectively; binding units which are arranged in the housing units, respectively, and bind the permanent magnets in the housing units, respectively; permanent magnet detectors which are arranged in the housing units, respectively, and detect whether the permanent magnets are housed in the housing units, respectively; and a control unit which controls the binding units to selectively keep the permanent magnets in a binding state or a nonbinding state on the basis of detection results of the permanent magnet detectors.

摘要翻译： 壳体装置包括分别容纳有多个永磁体的壳体单元; 分别布置在壳体单元中并且分别在壳体单元中固定永磁体的装订单元; 永磁体检测器分别布置在壳体单元中，并且分别检测永磁体是否容纳在壳体单元中; 以及控制单元，其基于永磁体检测器的检测结果来控制装订单元选择性地将永久磁铁保持在绑定状态或非绑定状态。

公开(公告)号：US08021357B2

公开(公告)日：2011-09-20

申请号：US11658509

申请日：2006-05-25

申请人： Shinsuke Tanaka ,  Hironao Kawano ,  Hironobu Takizawa

发明人： Shinsuke Tanaka ,  Hironao Kawano ,  Hironobu Takizawa

IPC分类号： A61K9/22

CPC分类号： A61M31/002 ,  A61M5/14248 ,  A61M5/14276 ,  A61M5/1452 ,  A61M5/1454 ,  A61M5/1486 ,  A61M5/172 ,  A61M5/3287 ,  A61M2005/14252 ,  A61M2005/14284

摘要： A body-insertable apparatus including a balloon for storing a medical fluid in a capsule-like casing, and an injection needle including an elastic membrane. The body-insertable apparatus discharges the medical fluid due to contraction of the balloon, applies a discharge pressure of the medical fluid to the elastic membrane to expand the elastic membrane, and projects the injection needle from the casing due to the expansion of the elastic membrane. Further, the body-insertable apparatus has a channel forming unit for forming a channel connecting to the balloon and a channel connecting to the injection needle, and a communication adjusting mechanism. The communication adjusting mechanism adjusts a communicated state between the channels and, thereby controlling the start of medical-fluid discharge operation by the balloon.

摘要翻译： 一种身体可插入装置，包括用于将胶囊状容纳在胶囊型壳体中的气囊，以及包括弹性膜的注射针。 身体导入装置由于气囊的收缩而排出医用液体，将药液的排出压力施加到弹性膜，使弹性膜膨胀，并且由于弹性膜的膨胀而将注射针从壳体突出 。 另外，身体插入装置具有用于形成连接到气囊的通道的通道形成单元和连接到注射针的通道，以及连通调节机构。 通信调整机构调整通道之间的通信状态，由此控制气囊的药液排出动作的开始。

公开(公告)号：US07960683B2

公开(公告)日：2011-06-14

申请号：US12547206

申请日：2009-08-25

申请人： Hironao Kawano ,  Ryoji Sato ,  Hironobu Takizawa

发明人： Hironao Kawano ,  Ryoji Sato ,  Hironobu Takizawa

IPC分类号： G01J3/50

CPC分类号： H04N5/2252 ,  A61B1/041 ,  H04N9/045 ,  H04N2005/2255

摘要： An observation apparatus includes a light radiating unit that radiates a plurality of element lights, each of which has a limited wavelength band, to an observation target; a light detecting unit that detects the plurality of element lights reflected by the observation target in a plurality of patterns by changing a weight for each of the element lights; and a processing unit that performs a procedure of separating a component of each of the element lights from a plurality of detection results of the light detecting unit based on the weight for each of the element lights of the light detecting unit.

摘要翻译： 观察装置包括将观察对象的波长带有有限的多个元件光照射的发光部， 光检测单元，通过改变每个元件光的重量来检测由多个图案中的观察目标反射的多个元素光; 以及处理单元，其基于光检测单元的每个元件光的重量，执行从光检测单元的多个检测结果中分离每个元件光的分量的过程。

公开(公告)号：US20100030026A1

公开(公告)日：2010-02-04

申请号：US12575985

申请日：2009-10-08

申请人： Akio Uchiyama ,  Hironao Kawano ,  Takeshi Yokoi ,  Hironobu Takizawa ,  Kenichi Arai ,  Kazushi Ishiyama ,  Masahiko Sendoh

发明人： Akio Uchiyama ,  Hironao Kawano ,  Takeshi Yokoi ,  Hironobu Takizawa ,  Kenichi Arai ,  Kazushi Ishiyama ,  Masahiko Sendoh

IPC分类号： A61B1/04

CPC分类号： A61B1/041 ,  A61B1/00158 ,  A61B34/73

摘要： A medical apparatus main body such as a capsule main body inserted in the body cavity includes a thrust generating mechanism such as a spiral projection. The medical apparatus main body further forms an information providing unit comprising at least one of a storing unit for storing a state of the thrust generating mechanism and a direction detecting unit for detecting the direction of the medical apparatus main body. An input unit instructs a thrust generating direction of the thrust generating mechanism and thus a control unit changes continuously or the like a thrust generating state of the thrust generating mechanism based on information from the information providing unit.

摘要翻译： 插入体腔内的胶囊主体等医疗装置主体包括螺旋形突起等推力产生机构。 医疗器具主体还形成信息提供单元，该信息提供单元包括用于存储推力产生机构的状态的存储单元和用于检测医疗设备主体的方向的方向检测单元中的至少一个。 输入单元指示推力产生机构的推力产生方向，因此控制单元基于来自信息提供单元的信息连续地改变推力发生机构的推力产生状态。

公开(公告)号：US20080051635A1

公开(公告)日：2008-02-28

申请号：US11893882

申请日：2007-08-16

申请人： Shinsuke Tanaka ,  Hironao Kawano ,  Akira Kikuchi ,  Hirofumi Tsuboi ,  Ryoji Sato ,  Hironobu Takizawa

发明人： Shinsuke Tanaka ,  Hironao Kawano ,  Akira Kikuchi ,  Hirofumi Tsuboi ,  Ryoji Sato ,  Hironobu Takizawa

IPC分类号： A61B1/06

CPC分类号： A61B1/06 ,  A61B1/041 ,  A61B5/4839

摘要： A capsule-type medical apparatus holds a drug such that a drug release such as dissolution can be realized under the same condition as in a case where the drug is delivered to an interior of a living body by itself, and realizes confirmation on whether the drug delivered to the interior of the living body is actually released to a site in the living body or not. The capsule-type medical apparatus includes a capsule-like casing which is formed in a suitable size for insertion into the living body, a net-like drug holding unit which houses a drug in a releasable manner with respect to a site in the living body, and an imaging unit which captures an image covering the drug held in the drug holding unit and a surrounding area of the drug. The imaging unit 4 captures an image as drug-source information indicating a release condition of the drug with respect to the site in the living body.

摘要翻译： 胶囊型医疗装置保持药物，使得在与药物自身输送到生物体内部的情况相同的条件下能够实现溶解等药物释放，并且实现药物的确认 送到生物体的内部实际上被释放到活体内的一个部位。 胶囊型医疗装置包括形成为适于插入生物体的适当尺寸的胶囊型壳体，网状药物保持单元，其以相对于生物体内的部位可释放的方式容纳药物 以及摄像单元，其捕获覆盖药物保持单元中保持的药物的图像和药物的周围区域。 成像单元4将图像作为指示药物相对于生物体中的部位的释放状态的药物源信息。

公开(公告)号：US20080035521A1

公开(公告)日：2008-02-14

申请号：US11645928

申请日：2006-12-27

申请人： Hironobu Takizawa ,  Hironao Kawano

发明人： Hironobu Takizawa ,  Hironao Kawano

IPC分类号： A61J1/03

CPC分类号： A61B1/041 ,  A61B1/00016 ,  A61B1/00144 ,  A61B1/00158 ,  A61B5/073 ,  A61B5/117

摘要： The present invention has an object to make it possible for a patient to take in a plurality of ingesta materials accurately and easily in a specific order. A capsule housing apparatus 6 according to the present invention houses a capsule endoscope 3 and a first fluid 7 in a housing area 12 of a package 10 and a second fluid 8 in another housing area 11 of the package 10. A partition wall 13 that penetrably separates the housing areas 11, 12 is provided between the housing areas 11, 12 of the package 10. The capsule housing apparatus 6 having such a configuration makes the first fluid 7, capsule endoscope 3, and second fluid 8 suppliable to the patient in the specific order based on numbers marked on the package 10 over the housing areas 11, 12.

摘要翻译： 本发明的目的是使患者能够以特定的顺序准确且容易地摄取多个摄取材料。 根据本发明的胶囊容纳装置6将胶囊内窥镜3和第一流体7容纳在包装10的容纳区域12中，并且将第二流体8容纳在包装10的另一个容纳区域11中。 在包装10的容纳区域11,12之间设置有可分离壳体区域11,12的分隔壁13。 具有这种结构的胶囊容纳装置6使得第一流体7，胶囊型内窥镜3和第二流体8可以基于在包装体10上标记的数字以特定的顺序提供给患者。