摘要:
The present invention provides the compound of formula (I) in a solid form which, as a bulk medicament for pharmaceutical manufacture, is uniform, has a high purity, and is easy to work with. The invention further provides a process for preparing this compound, and pharmaceutical compositions containing the same. A solid form of (8E,12E,14E)-7-{(4-cycloheptylpiperazin-1-yl)carbonyl}oxy-3,6,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-trien-11-olide which has uniform specifications and is easy to work with was developed.
摘要:
The present invention provides the compound of formula (I) in a solid form which, as a bulk medicament for pharmaceutical manufacture, is uniform, has a high purity, and is easy to work with. The invention further provides a process for preparing this compound, and pharmaceutical compositions containing the same. A solid form of (8E,12E,14E)-7-{(4-cycloheptylpiperazin-1-yl)carbonyl}oxy-3,6,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-trien-11-olide which has uniform specifications and is easy to work with was developed.
摘要:
A stator includes a stator coil that is formed of a plurality of electric wires each being comprised of an electric conductor having a substantially rectangular cross section and an insulating coat covering the electric conductor. The electric wires include a pair of first and second electric wires each having an end portion where the electric conductor is not covered by the insulating coat. Each of the end portions of the two electric wires includes a joined part at a distal end thereof; the joined parts of the end portions are joined together. At least one of the first and second electric wires has a bent part that is bent only once and adjoins the joined part of the end portion of the electric wire. The end portion of the at least one of the first and second electric wires includes at least part of the bent part.
摘要:
The present invention provides a novel bioactive substance having an antitumor activity and a process for producing it, and a medical use thereof. Namely, it provides a 12-membered ring macrolide compound represented by the following formula obtained from the incubation solution of Streptomyces sp. Mer. 11107 or a variant thereof, a pharmacologically acceptable salt thereof or a hydrate of them, and a process for producing it.
摘要:
A communication apparatus includes a discrimination unit which discriminates the current communication mode and a changing unit which changes a time out value for communication in accordance with the communication mode.
摘要:
An end point detector for detecting the monitor light to control the operation of an etching process by the etching equipment based on changes in the monitor light supplied from plasma etching equipment. The end point detector includes a sensor body for detecting the monitor light and a collector barrel for guiding the monitor light from the etching equipment to the sensor body, wherein the collector barrel is detachable from the sensor body.
摘要:
An electric rotating machine as disclosed herein includes an armature core having an outer peripheral portion with slots, a rotatable shaft having an outer periphery and rotatably supporting the armature core, a plurality of lower layer coils each having at opposite ends thereof respective lower layer coil protrusion portions, and a plurality of upper layer coils disposed radially outside of the lower layer coils and each having at opposite ends thereof respective upper layer coil protrusion portions. According to the novel method of this invention, the lower layer coil protrusion portions are bonded to the upper layer coil protrusion portions with a welding torch of an arc welding machine by radially moving at least one of the welding torch and boundary portions, at which the corresponding protrusion portions abut one another, relative to each other. By radially moving the welding torch and the boundary portions relative to each other, circumferentially adjacent bonded protrusion portions are smaller, mechanically stronger, and do not abut against one another.
摘要:
A key member, a method for insertion and/or removal of the fuel rods in a nuclear fuel assembly using the key member and a method of disassembling the nuclear fuel assembly using the same key member are disclosed. The key member has first projections and second projections formed on the opposite faces of an elongated key body. In the insertion or removal of the fuel rods or in the disassembling the nuclear fuel assembly, the key member is inserted into the grid and rotated to bring the first projections and the second projections into engagement with the straps of the grids and the springs on the straps to thereby the springs are deflected in a direction away from the dimples opposing to the springs. In this situation, the insertion and removal of the fuel rods can be carried out. Further, in disassembling the nuclear fuel assembly, space required for inserting the key member into the grids may be ensured by subjecting prescribed portions of control rod-guide pipes and instrumentation pipes to cutting work and bulging the cut ends to move the cut end away from that of the opposing cut ends of the cut piece. The space may be formed by removing the control rod-guide pipes and instrumentation pipes after having formed slits in the pipes.
摘要:
The present invention presents an apparatus to facilitate the loading of specific fuel rods into the specific grid cells of the grids of a fuel assembly. The loading apparatus utilizes air-pressure operated loading cylinders to push out the specific fuel rods from a fuel rod magazine into the corresponding grid cells. The loading apparatus operates in conjunction with a series of fuel rod support rollers which provide support to the fuel rods, being charged into the grids, from the underside of the fuel rods to prevent sagging of the tip end, thus avoiding scraping against the straps of the grids when entering the grid cells, and causing potentially harmful surface scratches on the fuel rods.
摘要:
A key member, a method for insertion and/or removal of the fuel rods in a nuclear fuel assembly using the key member and a method of disassembling the nuclear fuel assembly using the same key member are disclosed. The key member has first projections and second projections formed on the opposite faces of an elongated key body. In the insertion or removal of the fuel rods or in the disassembling the nuclear fuel assembly, the key member is inserted into the grid and rotated to bring the first projections and the second projections into engagement with the straps of the grids and the springs on the straps to thereby deflect the springs in a direction away from the dimples opposing the springs. In this situation, the insertion and removal of the fuel rods can be carried out. Further, in disassembling the nuclear fuel assembly, space required for inserting the key member into the grids may be ensured by subjecting prescribed portions of control rod-guide pipes and instrumentation pipes to cutting work and bulging the cut ends to move the cut end away from that of the opposing cut ends of the cut piece. The space may be formed by removing the control rod-guide pipes and instrumentation pipes after having formed slits in the pipes.