Novel lactam ring-opening enzyme and use thereof
    1.
    发明申请
    Novel lactam ring-opening enzyme and use thereof 有权
    新型内酰胺开环酶及其用途

    公开(公告)号:US20070203075A1

    公开(公告)日:2007-08-30

    申请号:US11710612

    申请日:2007-02-26

    CPC分类号: C12N9/86 C12P19/28

    摘要: An enzyme capable of reducing the antibiotic activity (i.e., toxicity) of streptothricin with respect to eukaryotic cells without sacrificing antibiotic activity with respect to prokaryotic cells is provided along with a streptothricin derivative having reduced toxicity with respect to eukaryotic cells while retaining antibiotic activity with respect to prokaryotic cells, and a manufacturing method thereof. By opening the lactam ring of streptothricin, a protein having the amino acid sequence according to SEQ ID NO: 2, 4, 6, 8, 10, 12, 14 or 16 of the invention can reduce the antibiotic activity of streptothricin D with respect to eukaryotic cells without sacrificing antibiotic activity with respect to prokaryotic cells.

    摘要翻译: 提供能够降低链霉素相对于真核细胞的抗生素活性(即毒性)而不牺牲相对于原核细胞的抗生素活性的酶以及相对于真核细胞毒性降低的链球菌素衍生物,同时保持抗生素活性 原核细胞及其制造方法。 通过打开链霉素的内酰胺环,具有根据本发明的SEQ ID NO:2,4,6,8,10,12,14或16的氨基酸序列的蛋白质可以降低链球菌D的抗生素活性,相对于 真核细胞,而不牺牲相对于原核细胞的抗生素活性。

    Lactam ring-opening enzyme and use thereof
    2.
    发明授权
    Lactam ring-opening enzyme and use thereof 有权
    内酰胺开环酶及其用途

    公开(公告)号:US07892784B2

    公开(公告)日:2011-02-22

    申请号:US11710612

    申请日:2007-02-26

    CPC分类号: C12N9/86 C12P19/28

    摘要: An enzyme capable of reducing the antibiotic activity (i.e., toxicity) of streptothricin with respect to eukaryotic cells without sacrificing antibiotic activity with respect to prokaryotic cells is provided along with a streptothricin derivative having reduced toxicity with respect to eukaryotic cells while retaining antibiotic activity with respect to prokaryotic cells, and a manufacturing method thereof. By opening the lactam ring of streptothricin, a protein having the amino acid sequence according to SEQ ID NO: 2, 4, 6, 8, 10, 12, 14 or 16 of the invention can reduce the antibiotic activity of streptothricin D with respect to eukaryotic cells without sacrificing antibiotic activity with respect to prokaryotic cells.

    摘要翻译: 提供能够降低链霉素相对于真核细胞的抗生素活性(即毒性)而不牺牲相对于原核细胞的抗生素活性的酶以及相对于真核细胞毒性降低的链球菌素衍生物,同时保持抗生素活性 原核细胞及其制造方法。 通过打开链霉素的内酰胺环,具有根据本发明的SEQ ID NO:2,4,6,8,10,12,14或16的氨基酸序列的蛋白质可以降低链球菌D的抗生素活性,相对于 真核细胞,而不牺牲相对于原核细胞的抗生素活性。

    Article sales data processing apparatus and sales data editing method
    3.
    发明授权
    Article sales data processing apparatus and sales data editing method 有权
    文章销售数据处理设备和销售数据编辑方法

    公开(公告)号:US08447660B2

    公开(公告)日:2013-05-21

    申请号:US12819525

    申请日:2010-06-21

    申请人: Hiroshi Takagi

    发明人: Hiroshi Takagi

    IPC分类号: G06Q30/00

    摘要: According to one embodiment, an article sales data processing apparatus includes a list display control unit, a selection unit, an editing acceptance unit, and an update unit. The list display control unit causes a list of articles sold in one transaction to be displayed in the details area. The selection unit accepts selection of an article, of the articles displayed in the details area. The editing acceptance unit causes the display unit to display an editing screen for the sales data of the article selected by the selection unit, and accepts editing of the sales data. When the sales data displayed in the editing screen is edited, the update unit updates the sales data of the article selected by the selection unit, of the sales data of each article stored in the transaction storage unit, to the edited data.

    摘要翻译: 根据一个实施例,商品销售数据处理装置包括列表显示控制单元,选择单元,编辑接收单元和更新单元。 列表显示控制单元使得在一个事务中出售的物品的列表被显示在细节区域中。 选择单元接受在细节区域中显示的物品的物品的选择。 编辑接收单元使显示单元显示由选择单元选择的文章的销售数据的编辑画面,并接受销售数据的编辑。 当在编辑画面中显示的销售数据被编辑时,更新单元将存储在交易存储单元中的每个商品的销售数据的选择单元所选择的商品的销售数据更新为编辑数据。

    PLAYLIST CREATION APPARATUS, PLAYLIST CREATION METHOD AND PLAYLIST CREATING PROGRAM
    4.
    发明申请
    PLAYLIST CREATION APPARATUS, PLAYLIST CREATION METHOD AND PLAYLIST CREATING PROGRAM 有权
    播放列表创建设备,播放列表创建方法和播放列表创建程序

    公开(公告)号:US20120254168A1

    公开(公告)日:2012-10-04

    申请号:US13419840

    申请日:2012-03-14

    IPC分类号: G06F17/30

    摘要: Disclosed herein is a playlist creation apparatus including a person specification section, a liking extraction section, a searching section, and a playlist creation section. The person specification section is adapted to specify a person captured in an image based on image data. Also, the liking extraction section is adapted to extract a liking of the person specified by said person specification section. The searching section is adapted to search, based on the liking extracted by said liking extraction section, for sound data of sound conforming to the liking. In addition, the a playlist creation section is adapted to create a playlist which defines a reproduction order of the sound data searched out by said searching section during displaying of the image based on the image data.

    摘要翻译: 这里公开了一种播放列表创建设备,包括人物指定部分,喜好提取部分,搜索部分和播放列表创建部分。 人员指定部分适于基于图像数据指定在图像中捕获的人物。 此外,喜好提取部分适于提取由所述人员指定部分指定的人的喜好。 搜索部分适于基于由所述喜好提取部分提取的喜好来搜索符合喜好的声音的声音数据。 此外,播放列表创建部分适于创建基于图像数据在显示图像期间定义由所述搜索部分搜索的声音数据的再现顺序的播放列表。

    Device and Manufacturing Resin Molded Articles for Use in Optical Elements, and Method for Manufacturing Optical Elements
    5.
    发明申请
    Device and Manufacturing Resin Molded Articles for Use in Optical Elements, and Method for Manufacturing Optical Elements 审中-公开
    用于光学元件的装置和制造树脂模制品以及用于制造光学元件的方法

    公开(公告)号:US20120187588A1

    公开(公告)日:2012-07-26

    申请号:US13498488

    申请日:2010-09-06

    IPC分类号: B29D11/00 B29C45/40

    摘要: A device for manufacturing resin molded articles for use in optical elements. Said device is provided with a first molding die which is fixed in place; a second molding die, being movable, which has, on a molding die surface of a cavity, a transfer surface for transferring an optical surface to a melted resin injected into the cavity; a nozzle for injecting a fluid under pressure into the melted resin injected into the cavity, thereby forming a void inside said melted resin; and an ejector pin that is provided in the second molding die, protruding from the molding surface thereof, to release a base material from the molding surface.

    摘要翻译: 一种用于制造用于光学元件的树脂模塑制品的装置。 所述装置设置有固定就位的第一成型模具; 第二成型模具,其可移动,其在空腔的成型模具表面上具有用于将光学表面转移到注入到所述空腔中的熔融树脂的转印面; 用于将压力下的流体注入到注入到空腔中的熔融树脂中的喷嘴,从而在所述熔融树脂内部形成空隙; 以及设置在第二成型模具中的从其模制表面突出的推顶销,以从模制表面释放基材。

    L-CYSTEINE-PRODUCING BACTERIUM AND A METHOD FOR PRODUCING L-CYSTEINE
    6.
    发明申请
    L-CYSTEINE-PRODUCING BACTERIUM AND A METHOD FOR PRODUCING L-CYSTEINE 有权
    L-丝氨酸生产细菌和生产L-儿茶素的方法

    公开(公告)号:US20110033902A1

    公开(公告)日:2011-02-10

    申请号:US12858590

    申请日:2010-08-18

    IPC分类号: C12P13/12 C12N1/21 C12P13/06

    CPC分类号: C12N1/20 C07K14/245 C12P13/12

    摘要: L-Cysteine, L-cystine, a derivative or precursor thereof, or a mixture thereof is produced by culturing a bacterium belonging to the family Enterobacteriaceae, which has L-cysteine-producing ability and has been modified so that the activity of a protein encoded by a tolC gene, for example, a protein defined in the following (a) or (b), is increased in a medium, and by collecting L-cysteine, L-cystine, a derivative or precursor thereof, or a mixture thereof from the medium: (a) a protein comprising the amino acid sequence of SEQ ID NO: 2, (b) a protein comprising the amino acid sequence of SEQ ID NO: 2, but wherein one or several amino acid residues are substituted, deleted, inserted or added, increase of which activity in the bacterium improves the ability of the bacterium to produce L-cysteine.

    摘要翻译: L-半胱氨酸,L-胱氨酸,其衍生物或其前体或其混合物通过培养属于具有L-半胱氨酸生产能力并已经被修饰的家族肠杆菌科的细菌产生,使得蛋白质的活性被编码 通过tolC基因,例如在以下(a)或(b)中定义的蛋白质在培养基中增加,并且通过将L-半胱氨酸,L-胱氨酸,其衍生物或其前体或其混合物从 培养基:(a)包含SEQ ID NO:2的氨基酸序列的蛋白质,(b)包含SEQ ID NO:2的氨基酸序列的蛋白质,但其中一个或几个氨基酸残基被取代,缺失, 插入或添加,细菌中哪种活性的增加提高了细菌产生L-半胱氨酸的能力。

    LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL, AND IMAGE FORMATION METHOD EMPLOYING THE SAME
    8.
    发明申请
    LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL, AND IMAGE FORMATION METHOD EMPLOYING THE SAME 审中-公开
    光敏平版印刷材料和使用其的图像形成方法

    公开(公告)号:US20100221663A1

    公开(公告)日:2010-09-02

    申请号:US12279819

    申请日:2007-02-01

    申请人: Hiroshi Takagi

    发明人: Hiroshi Takagi

    IPC分类号: G03F7/004 G03F7/20

    摘要: The present invention provides a light sensitive planographic printing plate material which excels in printing durability and tone reproduction property in high resolution printing as in FM screening, and an image formation method employing the light sensitive planographic printing plate material. The light sensitive planographic printing plate material is characterized in that a light sensitive layer containing a light sensitive composition containing an addition polymerizable ethylenic double bond-containing compound, a bisimidazole compound as a photopolymerization initiator, a polymer binder and a photosensitizing dye is provided on a support obtained by subjecting one surface of an aluminum plate to (1) chemically etching treatment in an aqueous alkali solution, (2) electrochemically roughening treatment in an aqueous nitric acid solution, (3) chemically etching treatment in an aqueous alkali solution, (4) electrochemically roughening treatment in an aqueous hydrochloric acid solution, (5) chemically etching treatment in an aqueous alkali solution, and (6) anodizing treatment.

    摘要翻译: 本发明提供了一种在FM筛选中在高分辨率印刷中印刷耐久性和色调再现性能优异的光敏平版印刷版材料,以及采用光敏平版印刷版材料的图像形成方法。 光敏平版印刷版材料的特征在于,含有含有可加聚丙烯双键的化合物,双咪唑化合物作为光聚合引发剂的光敏性组合物,聚合物粘合剂和光敏染料的感光层设置在 (1)在碱性水溶液中进行化学蚀刻处理,(2)在硝酸水溶液中进行电化学粗糙化处理,(3)在碱性水溶液中的化学蚀刻处理(4) )在盐酸水溶液中进行电化学粗化处理,(5)在碱性水溶液中进行化学蚀刻处理,和(6)阳极氧化处理。

    Aluminum support for planographic printing plate, its manufacturing process, and planographic printing plate material
    10.
    发明授权
    Aluminum support for planographic printing plate, its manufacturing process, and planographic printing plate material 失效
    用于平版印刷版的铝支架,其制造工艺和平版印刷版材料

    公开(公告)号:US07192689B2

    公开(公告)日:2007-03-20

    申请号:US11015079

    申请日:2004-12-16

    申请人: Hiroshi Takagi

    发明人: Hiroshi Takagi

    IPC分类号: G03F7/027 G03F7/09

    摘要: Disclosed is a process for manufacturing an aluminum support for a planographic printing plate material, the process comprising the steps of electrolytically surface-roughening an aluminum plate in an electrolytic solution, employing a sinewave alternating current; and anodizing the surface-roughened aluminum plate, the electrolytically surface-roughening step comprising a first stage of electrolytically surface-roughening the aluminum plate in a first electrolytic solution containing hydrochloric acid as a main component at a current density of D1 for t1 at a quantity of electricity of Q1 and a second stage of electrolytically surface-roughening the aluminum plate in a second electrolytic solution containing hydrochloric acid as a main component at a current density of D2 for t2 at a quantity of electricity of Q2.

    摘要翻译: 公开了一种用于制造平版印刷版材料的铝支架的方法,该方法包括以下步骤:利用正弦波交流电在电解液中电解表面粗糙化铝板; 对所述表面粗糙化的铝板进行阳极氧化处理,所述电解表面粗糙化工序包括在以1的电流密度为t 1的以盐酸为主要成分的第1电解液中对所述铝板进行电解表面粗糙化的第1阶段 电解质为Q1的第二阶段的电解液和第二阶段的电解质量为Q2的第二电解液中,以含有盐酸为主要成分的第二电解液以电流密度D 2对电解质进行电解表面粗化。