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1.发明申请Biological sample observation system and biological sample observation method 审中-公开生物样本观察系统和生物样本观察方法公开(公告)号：US20060000962A1
公开(公告)日：2006-01-05
申请号：US11149691
申请日：2005-06-10
IPC分类号： G02B27/40
CPC分类号： G02B21/365 , G02B21/245
摘要： An object is to provide a biological sample observation system wherein light damage to the biological sample is decreased, and observation can be performed accurately and quickly over a long period of time. A biological sample observation system which continuously obtains information on a biological sample that is cultured inside of a culturing container has: an imaging section which observes mutually different regions that are previously selected, among regions to be observed including the biological sample, through an object lens for observing the biological sample in the culturing container through a part of the culturing container; an autofocus section which detects the focusing of the object lens with respect to a predetermined region among the regions to be observed; and a focusing drive control section which controls the focusing of the object lens when the biological sample is observed using the imaging section, based on the detection result of the focusing previously performed by the autofocus section. After the focus detection is performed by the autofocus section, without being intervened by the focus detection using the autofocus section, and the different regions are continuously observed by the imaging section, with the focusing controlled by the focusing drive control section.
摘要翻译： 本发明的目的是提供一种生物样品观察系统，其中对生物样品的光损伤降低，并且可以在长时间内精确而快速地进行观察。 连续获取培养容器内培养的生物样品的信息的生物样本观察系统具有：成像部，其通过物镜观察包含生物体样本的待观察区域中预先选择的相互不同的区域 用于通过培养容器的一部分观察培养容器中的生物样品; 自动对焦部，其检测所述物镜相对于要观察的区域中的预定区域的聚焦; 以及聚焦驱动控制部，其基于由所述自动聚焦部先前执行的聚焦的检测结果，使用所述摄像部来观察所述生物样本时的所述物镜的聚焦。 在通过自动聚焦部执行焦点检测之后，不用通过使用自动聚焦部分的焦点检测进行干预，并且由成像部分连续观察不同的区域，聚焦由聚焦驱动控制部分控制。
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2.发明申请CELL CULTURE DETECTION APPARATUS, CELL CULTURE OBSERVATION APPARATUS, AND CELL CULTURE OBSERVATION METHOD 审中-公开细胞培养检测装置，细胞培养观察装置和细胞培养观察方法公开(公告)号：US20080131922A1
公开(公告)日：2008-06-05
申请号：US12022400
申请日：2008-01-30
申请人： Kayuri Muraki , Hiroyuki Imabayashi
发明人： Kayuri Muraki , Hiroyuki Imabayashi
摘要： A cell culture detection apparatus includes a culture vessel that houses cells together with a culture liquid, a culturing device that cultures the cells under predetermined culturing conditions, a detection device that detects a feature of the cells among the cells being cultured, and a light blocking device that blocks the culture vessel from environmental light when the feature is not detected.
摘要翻译： 细胞培养检测装置包括将细胞与培养液一起容纳的培养容器，在规定的培养条件下培养细胞的培养装置，检测被培养的细胞中的细胞特征的检测装置和遮光 当没有检测到特征时，阻挡培养容器的环境光的装置。
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3.发明授权Optical pick-up apparatus having hologram and beam splitter with birefringent member and polarizing film 失效具有全息图的光学拾取装置和具有双折射元件和偏光膜的分束器
公开(公告)号：US5621714A
公开(公告)日：1997-04-15
申请号：US400757
申请日：1995-03-08
CPC分类号： G11B7/1356 , G11B11/10543 , G11B7/124 , G11B7/126 , G11B7/127 , G11B7/131 , G11B7/1353 , G11B11/10576 , G11B7/09
摘要： An optical pick-up apparatus for reproducing information recorded on a magneto-optical record medium including a semiconductor laser emitting a linearly polarized laser beam, and a polarizing film provided between a glass prism and a uniaxial birefringent crystal prism. The laser beam emitted by the semiconductor laser is made incident upon the polarizing film via the glass prism and is reflected thereby. The apparatus further includes an objective lens projecting the laser beam reflected by the polarizing film onto the magneto-optical record medium as a fine spot and converging a return laser beam reflected by the record medium toward the polarizing film. The return beam transmitted through the polarizing film is refracted by the uniaxial birefringent crystal prism and is divided into ordinary light and extraordinary light, which are received by a first photodetector to produce a reproduced information signal. The return beam reflected by the polarizing film is made incident upon a hologram and is diffracted thereby into .+-.1-order beams which are received by a second photodetector to produce a focusing error signal and a tracking error signal.
摘要翻译： 一种用于再现记录在包括发射线性偏振激光束的半导体激光器的磁光记录介质上的信息的光学拾取装置，以及设置在玻璃棱镜和单轴双折射晶体棱镜之间的偏振膜。 由半导体激光器发射的激光束经由玻璃棱镜入射到偏振膜上并被反射。 该装置还包括将由偏振膜反射的激光束投影到磁光记录介质上的物镜作为细微点，并将由记录介质反射的返回激光束会聚到偏振膜。 透过偏光膜的返回光束被单轴双折射晶体棱镜折射，分为普通的光和非常的光，由第一光电检测器接收以产生再现的信息信号。 由偏振膜反射的返回光束入射到全息图上，并被衍射为由第二光电检测器接收的+/- 1次光束，以产生聚焦误差信号和跟踪误差信号。
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公开(公告)号：US20070087436A1
公开(公告)日：2007-04-19
申请号：US10552923
申请日：2004-04-09
摘要： An object of the present invention is to provide a method for introducing a physiologically active substance such as a gene into a cell, which introduces a physiologically active substance such as any given gene into any given cell in a view under a microscope, while significantly reducing invasiveness to the cell, and a device used for the above method. The present invention provides a method for introducing a physiologically active substance into a cell, which comprises: allowing a physiologically active substance to attach around a needle having a diameter of 500 nm or less, provided that it is able to be inserted into a cell; and inserting the above-described needle into the cell; and a microinjection device for carrying out the aforementioned method.
摘要翻译： 本发明的目的是提供一种将生物活性物质如基因导入细胞的方法，该细胞在显微镜下以任何给定的基因引入任何给定基因的生理活性物质，同时显着降低 对细胞的侵袭性，以及用于上述方法的装置。 本发明提供了一种将生理活性物质引入细胞的方法，其包括：使生理活性物质附着在直径为500nm以下的针上，只要其能够插入细胞中即可。 并将上述针插入细胞中; 以及用于实施上述方法的显微注射装置。
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公开(公告)号：US5814807A
公开(公告)日：1998-09-29
申请号：US840723
申请日：1997-04-25
IPC分类号： G02B5/30 , G02B27/28 , G11B7/12 , G11B7/135 , G11B7/22 , G11B11/105 , G02B7/04 , G02B27/64 , G11B7/00
CPC分类号： G11B7/1356 , G02B27/283 , G02B5/3083 , G11B11/10543 , G11B7/123 , G11B7/22
摘要： An optical pick-up head for reading writing information from on a magneto-optical record medium including a semiconductor laser, a multi-image plane parallel plate for separating an incident light beam emitted by the semiconductor laser from a return light beam reflected by the optical record medium and dividing the return beam transmitted through and refracted by the multi-image plane parallel plate into a plurality of return light beams, and a signal detecting photodetector receiving a plurality of return light beams, wherein the multi-image plane parallel plate is formed by first and second prisms made of birefringent material and is arranged such that major and minor axes of astigmatism introduced by the plane parallel plate are inclined by 45.degree. with respect to an information track. An optic axis of the first prism is set such that the return beam is separated into ordinary and extraordinary light beams having identical intensities and an optic axis of the second prism is rotated with respect to the optic axis of the first prism. The optical elements are positioned and mounted on a mounting substrate having guide walls formed by a photolithography.
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公开(公告)号：US5523643A
公开(公告)日：1996-06-04
申请号：US480885
申请日：1995-06-07
申请人： Takanao Fujimura , Tomoki Funakubo , Yougo Imai , Toshiharu Tsubata , Yoshihisa Taniguchi , Takashi Ouchi , Hiroyuki Imabayashi , Yukihiko Sawada , Katsuhiro Wakabayashi
发明人： Takanao Fujimura , Tomoki Funakubo , Yougo Imai , Toshiharu Tsubata , Yoshihisa Taniguchi , Takashi Ouchi , Hiroyuki Imabayashi , Yukihiko Sawada , Katsuhiro Wakabayashi
CPC分类号： H01L41/0906
摘要： An ultrasonic piezoelectric transducer and an ultrasonic actuator for performing enhanced elliptical vibration comprise a first laminated piezoelectric element having a first fixed end, a resonator mounted to the opposite end of the first laminated piezoelectric element, a second laminated piezoelectric element having one end thereof fixedly mounted to the resonator in a direction other than a vibrating direction of the first laminated piezoelectric element, and a load mass fixedly mounted to the opposite end of the second laminated piezoelectric element. This structure permits the enhanced elliptical vibration of the transducer to have a large, controllable amplitude.
摘要翻译： 用于进行增强的椭圆振动的超声波压电换能器和超声波致动器包括具有第一固定端的第一层压压电元件，安装在第一层叠压电元件的相对端的谐振器，其一端固定地安装在第二层叠压电元件 在与第一层压型压电元件的振动方向以外的方向上的谐振器，以及固定地安装在第二层压型压电元件的另一端的负载质量。 这种结构允许增强的换能器的椭圆振动具有大的可控振幅。
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公开(公告)号：US5804814A
公开(公告)日：1998-09-08
申请号：US447208
申请日：1995-05-22
CPC分类号： G11B7/1356 , G02B27/283 , G02B5/3083 , G11B11/10543 , G11B7/123 , G11B7/22
摘要： An optical pick-up head for reading writing information from on a magneto-optical record medium including a semiconductor laser, a multi-image plane parallel plate for separating an incident light beam emitted by the semiconductor laser from a return light beam reflected by the optical record medium and dividing the return beam transmitted through and refracted by the multi-image plane parallel plate into a plurality of return light beams, and a signal detecting photodetector receiving a plurality of return light beams, wherein the multi-image plane parallel plate is formed by first and second prisms made of birefringent material and is arranged such that major and minor axes of astigmatism introduced by the plane parallel plate are inclined by 45.degree. with respect to an information track. An optic axis of the first prism is set such that the return beam is separated into ordinary and extraordinary light beams having identical intensities and an optic axis of the second prism is rotated with respect to the optic axis of the first prism. The optical elements are positioned and mounted on a mounting substrate having guide walls formed by a photolithography.
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公开(公告)号：US5416375A
公开(公告)日：1995-05-16
申请号：US304083
申请日：1994-09-09
申请人： Tomoki Funakubo , Takanao Fujimura , Hiroyuki Imabayashi , Takashi Ouchi , Yoshihisa Taniguchi , Toshiharu Tsubata
发明人： Tomoki Funakubo , Takanao Fujimura , Hiroyuki Imabayashi , Takashi Ouchi , Yoshihisa Taniguchi , Toshiharu Tsubata
摘要： An ultrasonic motor comprising an elastic body, at least two laminated piezoelectric bodies clamped by a portion of the elastic body, an ultrasonic oscillator for exciting simultaneously a plurality of shrunk and retreated oscillation modes on the elastic body, to generate ultrasonic elliptic oscillation, and an element to be driven urged against a portion of the ultrasonic oscillator and movable with respect to the ultrasonic oscillator.
摘要翻译： 一种超声波电动机，其特征在于，包括弹性体，由所述弹性体的一部分夹持的至少2层叠压电体，在所述弹性体上同时激励多个收缩退避振荡模式的超声波振荡器，生成超声波椭圆振荡， 被驱动的元件被推压到超声波振荡器的一部分上并相对于超声波振荡器可移动。
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公开(公告)号：US5357164A
公开(公告)日：1994-10-18
申请号：US65195
申请日：1993-05-20
摘要： An ultrasonic motor characterized by comprising:an ultrasonic oscillator for generating ultrasonic oscillation on a specific surface;a movable body pressure-bonded to a specific surface of the ultrasonic oscillator for moving the movable body by the ultrasonic oscillator in a given direction by ultrasonic oscillation; anda sliding element provided on one of a contact surface of the ultrasonic oscillator and a contact surface of the movable body and having a porous oxide coating in which hydrators are formed to substantially fill small holes in the oxide coating.
摘要翻译： 一种超声波电动机，其特征在于包括：超声波振荡器，用于在特定表面上产生超声波振荡; 压接在所述超声波振荡器的特定表面上的移动体，用于通过超声波振荡使所述超声波振荡器沿给定方向移动所述可动体; 以及滑动元件，其设置在所述超声波振荡器的接触表面和所述可动体的接触表面中的一个上，并且具有多孔氧化物涂层，其中形成氢化器以基本上填充所述氧化物涂层中的小孔。
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10.发明授权Optical pick-up head and integrated type optical unit for use in optical pick-up head 失效用于光学拾音头的光学拾取头和集成型光学单元
公开(公告)号：US5898167A
公开(公告)日：1999-04-27
申请号：US105009
申请日：1998-06-26
CPC分类号： G11B7/1356 , G02B27/283 , G02B5/3083 , G11B11/10543 , G11B7/123 , G11B7/22
摘要： An optical pick-up head for reading writing information from on a magneto-optical record medium including a semiconductor laser, a multi-image plane parallel plate for separating an incident light beam emitted by the semiconductor laser from a return light beam reflected by the optical record medium and dividing the return beam transmitted through and refracted by the multi-image plane parallel plate into a plurality of return light beams, and a signal detecting photodetector receiving a plurality of return light beams, wherein the multi-image plane parallel plate is formed by first and second prisms made of birefringent material and is arranged such that major and minor axes of astigmatism introduced by the plane parallel plate are inclined by 45.degree. with respect to an information track. An optic axis of the first prism is set such that the return beam is separated into ordinary and extraordinary light beams having identical intensities and an optic axis of the second prism is rotated with respect to the optic axis of the first prism. The optical elements are positioned and mounted on a mounting substrate having guide walls formed by a photolithography.
摘要翻译： 一种用于从包括半导体激光器的磁光记录介质读取写入信息的光学拾取头，用于将由半导体激光器发射的入射光束与由光学器件反射的返回光束分离的多图像平面平行板 记录介质，并将通过多像平面平行板透射并折射的返回光束分割成多个返回光束，以及接收多个返回光束的信号检测光电检测器，其中形成多像平面平行板 通过由双折射材料制成的第一和第二棱镜，并且被布置成使得由平面平行板引入的散光的主轴和短轴相对于信息轨道倾斜45°。 第一棱镜的光轴被设置为使得返回光束被分离成具有相同强度的普通和非凡光束，并且第二棱镜的光轴相对于第一棱镜的光轴旋转。 光学元件被定位并安装在具有通过光刻形成的引导壁的安装基板上。
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