公开(公告)号：US07049342B2

公开(公告)日：2006-05-23

申请号：US10296206

申请日：2001-05-25

申请人： Hiroyuki Miyachi ,  Masahiro Nomura ,  Yukie Takahashi ,  Takahiro Tanase ,  Kouji Murakami ,  Masahiro Suzuki

发明人： Hiroyuki Miyachi ,  Masahiro Nomura ,  Yukie Takahashi ,  Takahiro Tanase ,  Kouji Murakami ,  Masahiro Suzuki

IPC分类号： A61K31/195 ,  C07C235/52

CPC分类号： C07C229/34 ,  C07B2200/07 ,  C07C69/734 ,  C07C69/738 ,  C07C233/55 ,  C07C235/38

摘要： The invention provides novel substituted phenylpropionic acid derivatives that bind to the receptor as ligands of human peroxisome proliferator-activated receptor α (PPARα) to activate and exhibit potent lipid-decreasing action, and processes for preparing them.It relates to substituted phenylpropionic acid derivatives represented by a general formula (1) [wherein R1 denotes a lower alkyl group with carbon atoms of 1 to 4, lower alkoxy group with carbon atoms of 1 to 3, trifluoromethyl group, trifluoromethoxy group, phenyl group which is unsubstituted or may have substituents, phenoxy group which is unsubstituted or may have substituents or benzyloxy group which is unsubstituted or may have substituents, R2 denotes a hydrogen atom, lower alkyl group with carbon atoms of 1 to 4 or lower alkoxy group with carbon atoms of 1 to 3, R3 denotes a lower alkoxy group with carbon atoms of 1 to 3, and the binding mode of A portion denotes —CH2CONH—, —NHCOCH2—, —CH2CH2CO—, —CH2CH2CH2—, —CH2CH2O—, —CONHCH2—, —CH2NHCH2—, —COCH2O—, —OCH2CO—, —COCH2NH— or —CHCH2CO—], their pharmaceutically acceptable salts and their hydrates, and processes for preparing them.

摘要翻译： 本发明提供新的取代的苯基丙酸衍生物，其结合受体作为人类过氧化物酶体增殖物激活受体α（PPARα）的配体，以活化并显示出有力的降脂作用，以及制备它们的方法。 它涉及由通式（1）表示的取代的苯基丙酸衍生物[其中R 1表示碳原子数为1〜4的低级烷基，碳原子数1〜3的低级烷氧基， 三氟甲基，三氟甲氧基，未取代或可具有取代基的苯基，未取代或可具有取代基的苯氧基或未取代或可具有取代基的苄氧基，R 2表示氢原子， 碳原子数为1〜3的碳原子数为1〜4的低级烷基，碳原子数1〜3的低级烷氧基，碳原子数为1〜3的低级烷氧基，A 部分表示-CH 2 CO 2，-NHCOCH 2 - ， - CH 2 CH 2 CO-， - CH 2 CH 2 CH 2 - ， - CH 2 CH 2 - O-（CH 2）2 CH 2 - ，-CONHCH 2 - ， - CH 2 NHCH 2 - ， - COCH 2 O - ， - OCH 2 - CO - ， - COCH 2 NH-或-CHCH 2 - CO-]，它们的药学上可接受的盐和它们的水合物，以及它们的制备方法。

公开(公告)号：US06506797B1

公开(公告)日：2003-01-14

申请号：US10009175

申请日：2001-12-10

申请人： Masahiro Nomura ,  Yukie Takahashi ,  Takahiro Tanase ,  Hiroyuki Miyachi ,  Masaki Tsunoda ,  Tomohiro Ide ,  Koji Murakami

发明人： Masahiro Nomura ,  Yukie Takahashi ,  Takahiro Tanase ,  Hiroyuki Miyachi ,  Masaki Tsunoda ,  Tomohiro Ide ,  Koji Murakami

IPC分类号： A01N3712

CPC分类号： C07D263/26 ,  A61K31/195 ,  C07C235/60 ,  C07C323/60

摘要： The invention provides novel substituted phenylpropanoic acid derivatives that activate by binding to receptor as ligands of human peroxisome preliferant-activated receptor &agr; (PPAR&agr;), and exhibit potent decreasing action on lipids in blood (cholesterol and triglyceride). It relates to a substituted phenylpropanoic acid derivatives represented by a general formula (1), their pharmaceutically acceptable salts and their hydrates, and processes for preparing them.

摘要翻译： 本发明提供新的取代苯丙酸衍生物，其通过与作为人过氧化物酶体增生物激活受体α（PPARα）的配体的受体结合而活化，并且对血液中的脂质（胆固醇和甘油三酸酯）表现出有效的降低作用。涉及取代的苯丙酸 由通式（1）表示的衍生物，其药学上可接受的盐及其水合物及其制备方法。

公开(公告)号：US20130120461A1

公开(公告)日：2013-05-16

申请号：US13558133

申请日：2012-07-25

申请人： Yukie Takahashi ,  Kei Imada

发明人： Yukie Takahashi ,  Kei Imada

IPC分类号： G09G5/00

CPC分类号： G06T5/004 ,  G06T2207/20016 ,  G06T2207/20201

摘要： According to one embodiment, an image processing method includes: generating reduced information obtained by reducing input image information with a reduction ratio; calculating a moving amount in a unit of a first display area based on the reduced information and reduced previous information obtained by reducing image information input prior to the input image information with the reduction ratio; calculating a moving amount in a unit of a second display area of the input image information by magnifying the moving amount in the unit of a first display area calculated with a first magnification ratio that is an inverse of the reduction ratio, and calculate an adjustment level in the unit of the second display area based on the moving amount in the unit of the second display area, which indicates a level of high frequency component image information to be blended on the input image information.

摘要翻译： 根据一个实施例，一种图像处理方法包括：产生通过以减小比减小输入图像信息而获得的缩减信息; 基于减少的信息计算第一显示区域的移动量，并且通过以减小比率减少输入图像信息之前输入的图像信息而获得的缩小的先前信息; 通过以与所述缩小比的倒数比的第一倍率相对应的以第一放大率计算的第一显示区域为单位放大移动量来计算输入图像信息的第二显示区域的单位的移动量，并且计算调整水平 基于第二显示区域单位的移动量，指示要对输入图像信息进行混合的高频分量图像信息的电平，以第二显示区域为单位。

公开(公告)号：US20120133826A1

公开(公告)日：2012-05-31

申请号：US13169973

申请日：2011-06-27

申请人： Yukie Takahashi

发明人： Yukie Takahashi

IPC分类号： H04N7/01 ,  G09G5/00

CPC分类号： H04N5/205 ,  H04N1/40068 ,  H04N7/0117

摘要： According to one embodiment, an image processor includes a generator, a high-resolution image generator, a separator, a texture generator, and a combiner. The generator compresses an input image to generate a low-resolution image. The high-resolution image generator generates, from the input image, a high-resolution image that is higher in resolution than the input image. The separator separates the low-resolution image generated by the generator into a texture component image and a frame component image. The texture generator generates texture component from the texture component image and the frame component image separated by the separator. The combiner combines the texture component generated by the texture generator with the high-resolution image generated by the high-resolution image generator to generate an output image.

摘要翻译： 根据一个实施例，图像处理器包括发生器，高分辨率图像生成器，分离器，纹理生成器和组合器。 发生器压缩输入图像以产生低分辨率图像。 高分辨率图像生成器从输入图像生成分辨率高于输入图像的高分辨率图像。 分离器将由发生器产生的低分辨率图像分离成纹理分量图像和帧分量图像。 纹理生成器从纹理分量图像和由分隔符分隔的帧分量图像生成纹理分量。 组合器将由纹理生成器生成的纹理分量与由高分辨率图像生成器生成的高分辨率图像组合以生成输出图像。

公开(公告)号：US08493508B2

公开(公告)日：2013-07-23

申请号：US13169973

申请日：2011-06-27

申请人： Yukie Takahashi

发明人： Yukie Takahashi

IPC分类号： H04N7/01 ,  H04N1/04 ,  G09G5/00

CPC分类号： H04N5/205 ,  H04N1/40068 ,  H04N7/0117

摘要： According to one embodiment, an image processor includes a generator, a high-resolution image generator, a separator, a texture generator, and a combiner. The generator compresses an input image to generate a low-resolution image. The high-resolution image generator generates, from the input image, a high-resolution image that is higher in resolution than the input image. The separator separates the low-resolution image generated by the generator into a texture component image and a frame component image. The texture generator generates texture component from the texture component image and the frame component image separated by the separator. The combiner combines the texture component generated by the texture generator with the high-resolution image generated by the high-resolution image generator to generate an output image.

摘要翻译： 根据一个实施例，图像处理器包括发生器，高分辨率图像生成器，分离器，纹理生成器和组合器。 发生器压缩输入图像以产生低分辨率图像。 高分辨率图像生成器从输入图像生成分辨率高于输入图像的高分辨率图像。 分离器将由发生器产生的低分辨率图像分离成纹理分量图像和帧分量图像。 纹理生成器从纹理分量图像和由分隔符分隔的帧分量图像生成纹理分量。 组合器将由纹理生成器生成的纹理分量与由高分辨率图像生成器生成的高分辨率图像组合以生成输出图像。

公开(公告)号：US20070252419A1

公开(公告)日：2007-11-01

申请号：US11661672

申请日：2004-09-03

申请人： Yukie Takahashi

发明人： Yukie Takahashi

IPC分类号： A47C1/00

CPC分类号： A47C3/026 ,  A47C3/025 ,  A47C7/14 ,  A47C9/002

摘要： A seating mechanism according to the present invention includes: a support provided on a holder; a seat plate provided pivotably in a substantially vertical direction around the support; and two control portions that are provided with the support therebetween, and apply, when a vertical force is applied to the seat plate, a resisting force against the vertical force to the seat plate. A chair according to the present invention includes the seating mechanism placed on a leg.

摘要翻译： 根据本发明的座位机构包括：设置在保持器上的支撑件; 围绕所述支撑件可枢转地设置在基本上垂直的方向上的座板; 以及两个控制部分，其间设置有支撑件，并且当向座板施加垂直力时施加抵抗对座板的垂直力的抵抗力。 根据本发明的椅子包括放置在腿上的座椅机构。

公开(公告)号：US06780431B1

公开(公告)日：2004-08-24

申请号：US10049937

申请日：2002-02-20

申请人： Mashiro Nomura ,  Koji Murakami ,  Masaki Tsunoda ,  Yukie Takahashi

发明人： Mashiro Nomura ,  Koji Murakami ,  Masaki Tsunoda ,  Yukie Takahashi

IPC分类号： A61K31426

CPC分类号： C07D277/34

摘要： The invention relates to substituted benzylthiazolidine-2,4-dione derivatives represented by a general formula (1) wherein R1 denotes a chlorine atom, bromine atom, nitro group, trifluoromethoxy group, ethoxy group, propoxy group or isopropoxy group, and R2 denotes a hydrogen atom or chlorine atom, their medicinally acceptable salts, their hydrates and a process for preparing them.

摘要翻译： 本发明涉及由通式（1）表示的取代的苄基噻唑烷-2,4-二酮衍生物，其中R 1表示氯原子，溴原子，硝基，三氟甲氧基，乙氧基，丙氧基或异丙氧基， R 2表示氢原子或氯原子，其药学上可接受的盐，它们的水合物及其制备方法。

公开(公告)号：US20130121605A1

公开(公告)日：2013-05-16

申请号：US13543114

申请日：2012-07-06

申请人： Kei Imada ,  Yukie Takahashi ,  Ryuji Sakai

发明人： Kei Imada ,  Yukie Takahashi ,  Ryuji Sakai

IPC分类号： G06T5/50

CPC分类号： G06T5/50 ,  G06T7/223 ,  G06T2207/20221

摘要： According to one embodiment, an image processing method includes: calculating in a unit of a display area, characteristic information indicating a characteristic included in the display area of first frame image information; searching for motion of a pixel between the first frame image information and second frame image information that is contained in the moving image information and that is posterior to the first frame image information; estimating characteristic information in the unit of the display area of the second frame image information based on the motion of the pixel and the characteristic information in the unit of the display area of the first frame image information; generating high-frequency image information in which a high-frequency component varies depending on the characteristic information in the unit of the display area of the second frame image information; and blending the high-frequency image information on the second frame image information.

摘要翻译： 根据一个实施例，图像处理方法包括：以显示区域为单位计算表示第一帧图像信息的显示区域中包括的特征的特征信息; 搜索所述第一帧图像信息和所述运动图像信息中包含的并且在所述第一帧图像信息之后的第二帧图像信息之间的像素的运动; 基于第一帧图像信息的显示区域的单位的像素的运动和特征信息来估计第二帧图像信息的显示区域的单位中的特征信息; 产生其中高频分量根据第二帧图像信息的显示区域的单位的特征信息而变化的高频图像信息; 以及将高频图像信息混合在第二帧图像信息上。