公开(公告)号：US4803550A

公开(公告)日：1989-02-07

申请号：US181133

申请日：1988-04-13

申请人： Hisao Yabe ,  Kenji Kimura ,  Masahide Kanno ,  Kiyoshi Tsuji ,  Jun Yoshinaga ,  Takeshi Yokoi ,  Kazuhiko Ozeki ,  Shinichi Nishigaki ,  Takeaki Nakamura ,  Yoshikazu Tojo ,  Hiromasa Suzuki

发明人： Hisao Yabe ,  Kenji Kimura ,  Masahide Kanno ,  Kiyoshi Tsuji ,  Jun Yoshinaga ,  Takeshi Yokoi ,  Kazuhiko Ozeki ,  Shinichi Nishigaki ,  Takeaki Nakamura ,  Yoshikazu Tojo ,  Hiromasa Suzuki

IPC分类号： A61B1/05 ,  H04N5/225 ,  H04N5/235 ,  A61B1/04 ,  A61B1/06

CPC分类号： A61B1/05 ,  H04N5/2354 ,  H04N2005/2255

摘要： An imaging apparatus for use in an electronic endoscope or the like is provided with a mechanically driven light-shielding plate, wherein imaging is effected by using a solid-state imaging device starting from a time when an amount of light shielded by this light-shielding plate becomes minimal, or imaging is effected repeatedly during a short exposure time within a transient period during which the amount of light shielded becomes minimal, and when an signal level of each image reaches a reference level, that signal is stored in a memory.

摘要翻译： 在电子内窥镜等中使用的成像装置设置有机械驱动的遮光板，其中通过使用固态成像装置来进行成像，该固态成像装置从由该遮光板屏蔽的光量开始 板变得最小，或者在遮光量变得最小的瞬时期间的短曝光时间内重复进行成像，并且当每个图像的信号电平达到参考电平时，该信号被存储在存储器中。

公开(公告)号：US5543831A

公开(公告)日：1996-08-06

申请号：US026203

申请日：1993-03-02

申请人： Kiyoshi Tsuji ,  Akinobu Uchikubo ,  Kenji Kimura ,  Masahito Goto ,  Tsutomu Hirai

发明人： Kiyoshi Tsuji ,  Akinobu Uchikubo ,  Kenji Kimura ,  Masahito Goto ,  Tsutomu Hirai

IPC分类号： G02B23/24 ,  A61B1/00 ,  A61B1/04 ,  A61B1/06 ,  A61B5/00 ,  G02B23/26 ,  H04N5/225 ,  H04N7/18

CPC分类号： A61B1/0669 ,  H04N7/183 ,  H04N2005/2255 ,  Y10S128/901 ,  Y10S128/908

摘要： A medical system having an endoscope probe intubated into a body, a signal processing circuit for processing a signal for the probe and an electric source circuit insulated from a commercial electric source. A part of the signal processing circuit connected to the probe is isolated by an isolation circuit to secure the safety. An impedance element is employed to prevent a malfunction by reducing an emission/permeation of noises. No adverse influence is thereby exerted on outside units.

摘要翻译： 具有插入到体内的内窥镜探针的医疗系统，用于处理用于探针的信号的信号处理电路和与商业电源绝缘的电源电路。 连接到探头的信号处理电路的一部分由隔离电路隔离以确保安全。 采用阻抗元件通过减少噪声的发射/渗透来防止故障。 不会对外部单元产生不利影响。

公开(公告)号：US5010395A

公开(公告)日：1991-04-23

申请号：US322038

申请日：1989-03-13

申请人： Kiyoshi Tsuji ,  Kenji Kimura

发明人： Kiyoshi Tsuji ,  Kenji Kimura

IPC分类号： A61B1/05 ,  H04N5/217 ,  H04N5/225 ,  H04N5/243 ,  H04N5/372 ,  H04N9/72

CPC分类号： H04N5/2173 ,  H04N5/243 ,  H04N9/72 ,  H04N2005/2255

摘要： The solid state imaging apparatus having a black level correcting circuit of this invention has an imaging device provided with a solid state imaging device and a signal processing device connected to this imaging device, processing the picture image signal obtained by the solid state imaging device and outputting a video signal. The signal processing device is provided with a gain controlling amplifier receiving the photoelectrically converted output of the solid state imaging device and variably gain-controlling it and a direct current-clamping circuit direct current-clamping the optical black part included in the output signal of the solid state imaging device and stabilizing the black level of the video signal.

摘要翻译： 具有本发明的黑电平校正电路的固体摄像装置具有：摄像装置，具备与该成像装置连接的固体摄像装置和信号处理装置，处理由固体摄像装置得到的图像信号，并输出 视频信号。 信号处理装置设置有增益控制放大器，其接收固态成像装置的光电转换输出并且可变地增益控制它，以及直流钳位电路直流钳位包含在输出信号中的光学黑色部分 固态成像装置，稳定视频信号的黑电平。

公开(公告)号：US4884134A

公开(公告)日：1989-11-28

申请号：US238061

申请日：1988-08-30

申请人： Kiyoshi Tsuji ,  Kenji Kimura ,  Yoshihiro Okada

发明人： Kiyoshi Tsuji ,  Kenji Kimura ,  Yoshihiro Okada

IPC分类号： G02B23/24 ,  A61B1/04 ,  A61B1/05 ,  H04N5/225 ,  H04N5/235 ,  H04N7/18

CPC分类号： A61B1/05 ,  H04N3/1556 ,  H04N5/2354 ,  H04N2005/2255 ,  Y10S600/921

摘要： An endoscope apparatus has a storage-time switching circuit for shortening the charge storage time of a solid state imaging device provided with a photoelectric conversion function, and the quantity of illuminating light to be projected an object is increased in association with the operation of this switching circuit. In this transient process of increasing the quantity of illuminating light, the level of video signals obtained by imaging is compared with a proper reference level. If the level of the video signals reaches the reference level, the video signals are stored in a storage circuit. Accordingly, it is possible to obtain a frozen picture which is scarcely blurred.

摘要翻译： 内窥镜装置具有用于缩短设置有光电转换功能的固态成像装置的电荷存储时间的存储时间切换电路，并且与该切换的操作相关联地增加要投射的对象的照明光量 电路。 在这种增加照明光量的瞬态过程中，通过成像获得的视频信号的电平与适当的参考电平进行比较。 如果视频信号的电平达到参考电平，则视频信号被存储在存储电路中。 因此，可以获得几乎不模糊的冻结图像。

公开(公告)号：US4860095A

公开(公告)日：1989-08-22

申请号：US179625

申请日：1988-04-08

申请人： Kenji Kimura ,  Kiyoshi Tsuji

发明人： Kenji Kimura ,  Kiyoshi Tsuji

IPC分类号： H04N5/222 ,  A61B1/05 ,  H04N5/225 ,  H04N5/232 ,  H04N5/335 ,  H04N5/341 ,  H04N5/357 ,  H04N5/372 ,  H04N5/374 ,  H04N5/378

CPC分类号： H04N5/23203 ,  A61B1/05 ,  H04N2005/2255

摘要： A video endoscope apparatus including an insertion section insertable into a cavity of a patient body under inspection a solid state image sensor arranged at a distal end of the insertion section for converting an optical image of the cavity into an electric signal a video processor unit including a driving circuit for generating a driving signal including vertical and horizontal driving pulses and a reset pulse for the solid state image sensor, and a video processing circuit for processing the electric signal supplied from the solid state image sensor to derive an image signal to be displayed on a monitor is provided with circuitry for compensating for image signal distortion caused by aberrations in the driving and reset pulses received at the insertion section due to differing signal cable lengths between the insertion section and the video processing unit.

摘要翻译： 一种视频内窥镜装置，包括插入部分，其被插入到被检查的患者身体的空腔中，固体图像传感器布置在插入部分的远端处，用于将空腔的光学图像转换为电信号，视频处理器单元包括 驱动电路，用于产生包括垂直和水平驱动脉冲的驱动信号和用于固态图像传感器的复位脉冲;以及视频处理电路，用于处理从固态图像传感器提供的电信号，以导出要显示的图像信号 监视器具有电路，用于补偿由插入部分和视频处理单元之间的不同信号电缆长度引起的在插入部分接收的驱动和复位脉冲中的像差引起的图像信号失真。

公开(公告)号：US4860091A

公开(公告)日：1989-08-22

申请号：US302550

申请日：1989-01-26

申请人： Kenji Kimura ,  Kiyoshi Tsuji

发明人： Kenji Kimura ,  Kiyoshi Tsuji

IPC分类号： H04N9/68 ,  H04N9/77

CPC分类号： H04N9/68 ,  H04N9/77

摘要： A composite video signal is supplied to chrominance and luminance signal separators. A chrominance signal is compared by a phase comparator with an average phase signal, and a difference between them is supplied to a control terminal of a phase modulator. The chrominance signal is input to the phase modulator. The phase averaging circuit, phase comparator, and phase modulator together constitute a hue emphasizing circuit. An output from the hue emphasizing circuit (output from phase modulator) is supplied to a mixer via a gain control amplifier (GCA). The chrominance signal is input to a level detector, where it is envelope-detected. An output from the level detector is supplied to a gain control terminal of the GCA. An output from the GCA emphasizing circuit (output from GCA) is a hue- and saturation-emphasized chrominance signal, and is supplied to the first input terminal of the mixer. A luminance signal is put to a phase shifter via a mixer. A hue-emphasized chrominance signal which is output from the phase comparator is subjected to quadratic differentiation by a differential circuit, and is input as a gain control input to a mixer. The last-mentioned mixer, differential circuit, and phase shifter together constitute an aperture compensator. The shift amount is set in the phase shifter, so as to compensate for a difference between the chrominance and luminance signals generated from the hue emphasizing circuit and the aperture compensator, respectively.

摘要翻译： 复合视频信号被提供给色度和亮度信号分离器。 色相信号通过相位比较器与平均相位信号进行比较，并且它们之间的差被提供给相位调制器的控制端。 色度信号被输入到相位调制器。 相位平均电路，相位比较器和相位调制器一起构成色调强调电路。 来自色调强调电路（从相位调制器输出）的输出通过增益控制放大器（GCA）提供给混频器。 色度信号被输入到电平检测器，在那里它被包络检测。 来自电平检测器的输出被提供给GCA的增益控制端。 来自GCA强调电路（GCA的输出）的输出是色相和饱和度强调的色度信号，并被提供给混频器的第一输入端。 通过混频器将亮度信号送入移相器。 从相位比较器输出的色相强调色度信号经差分电路进行二次微分，并作为增益控制输入输入混频器。 最后提到的混频器，差分电路和移相器一起构成孔径补偿器。 偏移量设定在移相器中，以分别补偿从色相强调电路和孔径补偿器产生的色度和亮度信号之间的差异。

公开(公告)号：US06319197B1

公开(公告)日：2001-11-20

申请号：US08888671

申请日：1997-07-07

申请人： Kiyoshi Tsuji ,  Akinobu Uchikubo ,  Kenji Kimura ,  Masahito Goto ,  Tsutomu Hirai

发明人： Kiyoshi Tsuji ,  Akinobu Uchikubo ,  Kenji Kimura ,  Masahito Goto ,  Tsutomu Hirai

IPC分类号： A61B104

CPC分类号： A61B1/0669 ,  H04N7/183 ,  H04N2005/2255 ,  Y10S128/901 ,  Y10S128/908

摘要： A medical system having an endoscope probe intubated into a body, a signal processing circuit for processing a signal for the probe and an electric source circuit insulated from a commercial electric source. A part of the signal processing circuit connected to the probe is isolated by an isolation circuit to secure the safety. An impedance element is employed to prevent a malfunction by reducing an emission/permeation of noises. No adverse influence is thereby exerted on outside units.

摘要翻译： 具有插入到体内的内窥镜探针的医疗系统，用于处理用于探针的信号的信号处理电路和与商业电源绝缘的电源电路。 连接到探头的信号处理电路的一部分由隔离电路隔离以确保安全。 阻抗元件用于通过减少噪声的发射/渗透来防止故障。 不会对外部单元产生不利影响。

公开(公告)号：US5335662A

公开(公告)日：1994-08-09

申请号：US81141

申请日：1993-06-25

申请人： Kenji Kimura ,  Kiyoshi Tsuji

发明人： Kenji Kimura ,  Kiyoshi Tsuji

IPC分类号： A61B1/04 ,  A61B1/05 ,  G02B23/24 ,  H04N5/225 ,  H04N7/18 ,  A61B8/00

CPC分类号： A61B1/00059 ,  A61B1/05 ,  G02B23/2484 ,  H04N5/335 ,  H04N7/18 ,  H04N2005/2255

摘要： A plurality of probes having image pickup elements differing from each other in image pickup system from each other are used to display an image image-picked-up on a monitor, and a connector of the used image pickup probe is connected to an exclusive adaptor, whereby a drive adapted for the image pickup element is applied to subject the image pickup element to preprocess processing suited for an output signal outputted from the image pickup element. The adaptor is mounted on a signal processing apparatus body, whereby substantially common process processing is subjected to a signal after the preprocess processing by the signal processing apparatus body, to generate a standard image signal. Thus, the standard image signal is displayed on a monitor.

摘要翻译： 在图像拾取系统中具有彼此不同的图像拾取元件的多个探针被用于在监视器上显示拾取的图像图像，并且所使用的图像拾取探针的连接器连接到专用适配器， 由此应用适于图像拾取元件的驱动器来对图像拾取元件进行对从图像拾取元件输出的输出信号的预处理处理。 适配器安装在信号处理装置主体上，由此在由信号处理装置主体进行预处理处理之后，对基本上共同的处理处理进行信号处理，以生成标准图像信号。 因此，标准图像信号被显示在监视器上。

公开(公告)号：US4814859A

公开(公告)日：1989-03-21

申请号：US123975

申请日：1987-11-20

申请人： Kenji Kimura ,  Kiyoshi Tsuji

发明人： Kenji Kimura ,  Kiyoshi Tsuji

IPC分类号： H04N9/68 ,  H04N9/77 ,  H04N9/71 ,  H04N9/74

CPC分类号： H04N9/68 ,  H04N9/77

摘要： A composite video signal is supplied to chrominance and luminance signal separators. A chrominance signal is compared by a phase comparator with an average phase signal, and a difference between them is supplied to a control terminal of a phase modulator. The chrominance signal is input to the phase modulator. The phase averaging circuit, phase comparator, and phase modulator together constitute a hue emphasizing circuit. An output from the hue emphasizing circuit (output from phase modulator) is supplied to a mixer via a gain control amplifier (GCA). The chrominance signal is input to a level detector, where it is envelope-detected. An output from the level detector is supplied to a gain control terminal of the GCA. An output from the GCA emphasizing circuit (output from GCA ) is a hue- and saturation-emphasized chrominance signal, and is supplied to the first input terminal of the mixer. A luminance signal is input to a phase shifter via a mixer. A hue-emphasized chrominance signal which is output from the phase comparator is subjected to quadratic differentiation by a differential circuit, and is input as a gain control input to a mixer. The last mentioned mixer, differential circuit, and phase shifter together constitute an aperature compensator. The shift amount is set in the phase shifter, so as to compensate for a difference between the chrominance and luminance signals generated from the hue emphasizing circuit and the aperture compensator, respectively.

摘要翻译： 复合视频信号被提供给色度和亮度信号分离器。 色相信号通过相位比较器与平均相位信号进行比较，并且它们之间的差被提供给相位调制器的控制端。 色度信号被输入到相位调制器。 相位平均电路，相位比较器和相位调制器一起构成色调强调电路。 来自色调强调电路（从相位调制器输出）的输出通过增益控制放大器（GCA）提供给混频器。 色度信号被输入到电平检测器，在那里它被包络检测。 来自电平检测器的输出被提供给GCA的增益控制端。 来自GCA强调电路（GCA的输出）的输出是色相和饱和度强调的色度信号，并被提供给混频器的第一输入端。 亮度信号通过混频器输入到移相器。 从相位比较器输出的色相强调色度信号经差分电路进行二次微分，并作为增益控制输入输入混频器。 最后提到的混频器，差分电路和移相器一起构成一个温度补偿器。 偏移量设定在移相器中，以分别补偿从色相强调电路和孔径补偿器产生的色度和亮度信号之间的差异。

公开(公告)号：US5571810A

公开(公告)日：1996-11-05

申请号：US422545

申请日：1995-04-13

申请人： Masaaki Matsuo ,  Kiyoshi Tsuji ,  Nobukiyo Konishi ,  Katsuya Nakamura

发明人： Masaaki Matsuo ,  Kiyoshi Tsuji ,  Nobukiyo Konishi ,  Katsuya Nakamura

IPC分类号： C07D333/12 ,  C07D333/22 ,  C07D333/24 ,  C07D333/32 ,  C07D333/34 ,  C07D333/36 ,  C07D333/38 ,  C07D409/12 ,  A61K31/535 ,  A61K31/38 ,  A61K31/42 ,  A61K31/495

CPC分类号： C07D409/12 ,  C07D333/12 ,  C07D333/22 ,  C07D333/24 ,  C07D333/32 ,  C07D333/34 ,  C07D333/36 ,  C07D333/38

摘要： This invention relates to new thiophene derivatives having antiinflammatory and analgesic activities and represented by the general formula [I]: ##STR1## wherein R.sup.1 is hydrogen, halogen, cyano, substituted lower alkyl, substituted or unsubstituted lower alkenyl, acyl, nitro, substituted or unsubstituted amino, sulfo, substituted or unsubstituted sulfamoyl, N-containing heterocyclicsulfonyl, hydoxy, substituted or unsubstituted heterocyclic group,R.sup.2 is substituted or unsubstituted aryl, andR.sup.3 is substituted or unsubstituted aryl, provided that R.sup.3 is aryl substituted with substituent(s) selected from the group consisting of amino, mono(lower)-alkylamino, acylamino, lower alkyl(acyl)amino and sulfamoyl when R.sup.1 is hydrogen, halogen or cyano, and pharmaceutically acceptable salts thereof, to processes for the preparation thereof and to a pharmaceutical composition comprising the same.

摘要翻译： 本发明涉及具有抗炎和止痛活性的新噻吩衍生物，由通式[I]表示：其中R 1是氢，卤素，氰基，取代的低级烷基，取代或未取代的低级烯基，酰基，硝基 取代或未取代的氨基，磺基，取代或未取代的氨磺酰基，含N杂环基磺酰基，羟基，取代或未取代的杂环基，R2为取代或未取代的芳基，R3为取代或未取代的芳基，条件是R3为被取代基取代的芳基 s）选自氨基，单（低级） - 烷基氨基，酰氨基，低级烷基（酰基）氨基和氨磺酰基，当R 1为氢时，卤素或氰基，及其药学上可接受的盐，其制备方法和 包含其的药物组合物。