公开(公告)号：US4792565A

公开(公告)日：1988-12-20

申请号：US38971

申请日：1987-04-16

申请人： Hitoshi Shimotori ,  Tutomu Ishii ,  Hideo Yamazaki ,  Toshiaki Kuwatsuka ,  Yuji Yanase ,  Yoshinori Tanaka

发明人： Hitoshi Shimotori ,  Tutomu Ishii ,  Hideo Yamazaki ,  Toshiaki Kuwatsuka ,  Yuji Yanase ,  Yoshinori Tanaka

IPC分类号： C07D231/12 ,  A01N25/02 ,  A01N43/56 ,  C07D231/14 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D231/16

CPC分类号： C07D403/12 ,  A01N43/56 ,  C07D231/14 ,  C07D405/12 ,  C07D409/12

摘要： Novel pyrazole derivatives of the general formula (I) ##STR1## wherein R.sup.1 represents an alkyl, haloalkyl, alkenyl, haloalkenyl or phenyl group, R.sup.2 and R.sup.3 each represent a hydrogen or halogen atom, or an alkyl, haloalkyl, alkoxy, alkoxyalkyl or phenyl group, and R.sup.4 represents an alkyl, alkenyl, haloalkenyl or phenyl group, or a heterocyclic aromatic group which contains at least one of oxygen, nitrogen and sulfur atoms and may be unsubstituted or substituted,which are useful as agricultural and horticultural fungicides. The pyrazole derivatives can be produced by reacting compounds of the general formula (III) ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are as defined above, and X represents a halogen atom,with aminoacetonitriles of the general formula (IV) ##STR3## wherein R.sup.4 is as defined above, or salts thereof.

摘要翻译： 通式（I）的新型吡唑衍生物其中R 1表示烷基，卤代烷基，烯基，卤代烯基或苯基，R 2和R 3各自表示氢或卤素原子，或烷基，卤代烷基，烷氧基， 烷氧基烷基或苯基，R4表示烷基，链烯基，卤代烯基或苯基，或含有氧，氮和硫原子中的至少一个的杂环芳基，可以是未取代或取代的，可用作农业和园艺杀真菌剂 。 吡唑衍生物可以通过使通式（III）的化合物（III）（其中R1，R2和R3如上定义，X​​代表卤素原子）与通式（IV）的氨基乙腈反应， （IV）其中R 4如上所定义，或其盐。

公开(公告)号：US4980363A

公开(公告)日：1990-12-25

申请号：US259817

申请日：1988-10-19

申请人： Hitoshi Shimotori ,  Yoshiro Kanemoto ,  Hideo Yamazaki ,  Tsutomu Ishii ,  Shuji Ozawa ,  Yuji Yanase ,  Toshiaki Kuwatsuka ,  Yoshinori Tanaka ,  Takeshi Sekine ,  Keiko Shinada

发明人： Hitoshi Shimotori ,  Yoshiro Kanemoto ,  Hideo Yamazaki ,  Tsutomu Ishii ,  Shuji Ozawa ,  Yuji Yanase ,  Toshiaki Kuwatsuka ,  Yoshinori Tanaka ,  Takeshi Sekine ,  Keiko Shinada

IPC分类号： A01N43/74 ,  A01N43/78 ,  A01N43/80 ,  C07D275/02 ,  C07D275/03 ,  C07D277/56 ,  C07D417/12 ,  C07D521/00

CPC分类号： C07D275/03 ,  A01N43/74 ,  A01N43/78 ,  A01N43/80 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D277/56 ,  C07D417/12

摘要： An amide derivative represented by the following general formula (I) ##STR1## wherein one of X and Y represents a sulfur atom and the other represents a carbon atom, Z represents a nitrile or thioamide group, each of R.sup.1 and R.sup.2 represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 6 carbon atoms, a halomethyl group or a phenyl group, and R.sup.3 represents an alkenyl group having 2 to 6 carbon atoms, a haloalkenyl group having 2 to 4 carbon atoms, a furyl group, a thienyl group, an alkoxy group having 1 to 4 carbon atoms, an alkylthio group having 1 to 4 carbon atoms, an alkynyloxy group having 3 to 5 carbon atoms, an alkynylthio group having 3 to 5 carbon atoms, a pyrazolyl group, or an unsubstituted or halo-substituted phenyl group; processes for producing the amide derivative; an agricultural-horicultural fungicide comprising the amide derivative as an active ingredient; and to an agricultural-horicultural fungicidal composition comprising the amide derivative of general formula (I) as an active ingredient.

公开(公告)号：US5104886A

公开(公告)日：1992-04-14

申请号：US545026

申请日：1990-06-28

申请人： Hitoshi Shimotori ,  Yoshiro Kanemoto ,  Hideo Yamazaki ,  Tsutomu Ishii ,  Shuji Ozawa ,  Yuji Yanase ,  Toshiaki Kuwatsuka ,  Yoshinori Tanaka ,  Takeshi Sekine ,  Keiko Shinada

发明人： Hitoshi Shimotori ,  Yoshiro Kanemoto ,  Hideo Yamazaki ,  Tsutomu Ishii ,  Shuji Ozawa ,  Yuji Yanase ,  Toshiaki Kuwatsuka ,  Yoshinori Tanaka ,  Takeshi Sekine ,  Keiko Shinada

IPC分类号： A01N43/74 ,  A01N43/78 ,  A01N43/80 ,  C07D275/02 ,  C07D275/03 ,  C07D277/56 ,  C07D417/12 ,  C07D521/00

CPC分类号： C07D275/03 ,  A01N43/74 ,  A01N43/78 ,  A01N43/80 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D277/56 ,  C07D417/12

摘要： An amide derivative represented by the following general formula (I) ##STR1## wherein one of X and Y represents a sulfur atom and the other represents a carbon atom, Z represents a nitrile or thioamide group, each of R.sup.1 and R.sup.2 represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 6 carbon atoms, a halomethyl group or a phenyl group, and R.sup.3 represents an alkenyl group having 2 to 6 carbon atoms, a haloalkenyl group having 2 to 4 carbon atoms, a furyl group, a thienyl group, an alkoxy group having 1 to 4 carbon atoms, an alkylthio group having 1 to 4 carbon atoms, an alkynyloxy group having 3 to 5 carbon atoms, an alkynylthio group having 3 to 5 carbon atoms, a pyrazolyl group, or an unsubstituted or halo-substituted phenyl group;processes for producing the amide derivative; an agricultural-horticultural fungicide comprising the amide derivative as an active ingredient; and to an agricultural-horticultural fungicidal composition comprising the amide derivative of general formula (I) as an active ingredient.

公开(公告)号：US4814337A

公开(公告)日：1989-03-21

申请号：US38895

申请日：1987-04-16

申请人： Katsutoshi Ishikawa ,  Hitoshi Shimotori ,  Noboru Iida ,  Toshiaki Kuwatsuka ,  Junya Fujiwara ,  Yuji Yanase ,  Takeshi Sekino

发明人： Katsutoshi Ishikawa ,  Hitoshi Shimotori ,  Noboru Iida ,  Toshiaki Kuwatsuka ,  Junya Fujiwara ,  Yuji Yanase ,  Takeshi Sekino

IPC分类号： A01N25/30 ,  A01N43/54 ,  A01N47/40 ,  A01P3/00 ,  C07D239/38 ,  C07D239/24

CPC分类号： A01N43/54 ,  C07D239/38

摘要： Disclosed are dihalogenothiocyanopyrimidine derivatives of the general formula ##STR1## wherein X and Y are halogen atoms, a process for preparing such derivatives, as well as agricultural and horticultural fungicidal compositions containing such a derivative as active ingredient.

摘要翻译： 公开了通式为其中X和Y为卤素原子的二卤代硫代氰基嘧啶衍生物，制备该衍生物的方法，以及含有这种衍生物作为活性成分的农业和园艺杀真菌组合物。

公开(公告)号：US5240951A

公开(公告)日：1993-08-31

申请号：US761217

申请日：1991-09-19

申请人： Hitoshi Shimotori ,  Yuji Yanase ,  Takeshi Sekino ,  Katsutoshi Ishikawa ,  Toshiaki Kuwatsuka ,  Hiroharu Tanikawa ,  Hideo Kawashima ,  Naofumi Tomura ,  Yoshiro Kanemoto

发明人： Hitoshi Shimotori ,  Yuji Yanase ,  Takeshi Sekino ,  Katsutoshi Ishikawa ,  Toshiaki Kuwatsuka ,  Hiroharu Tanikawa ,  Hideo Kawashima ,  Naofumi Tomura ,  Yoshiro Kanemoto

IPC分类号： A01N43/80 ,  C07D275/02 ,  C07D275/03

CPC分类号： C07D275/03 ,  A01N43/80

摘要： Application of a rice blast control agent containing an isothiazolecarboxylic acid derivative of the below-described formula, which shows excellent activity against rice blast (Pyricularia oryzae) in rice cultivation, to the water surface of a paddy rice field results in the absorption of the derivative through roots of rice plants, so that the resistance of the rice plants can be enhanced. ##STR1## wherein R.sup.1 and R.sup.2 independently mean a hydrogen or halogen atom or a particular group, and Y stands for an OR.sub.3 group (R.sup.3 being a hydrogen or alkali metal atom or a particular group), an NHR.sup.4 group (R.sup.4 being a hydrogen atom or a particular group), or a morpholino group.

摘要翻译： 在水稻栽培中将含有对稻瘟病稻瘟病（Pyricularia oryzae）具有优异活性的下述式的异噻唑羧酸衍生物的稻瘟病控制剂施用于水稻田的水面，导致衍生物的吸收 通过水稻根系，可以提高水稻的抗性。 其中R1和R2独立地表示氢或卤素原子或特定基团，Y表示OR3基团（R3表示氢或碱金属原子或特定基团），NHR4基团（R4表示氢原子 或特定组）或吗啉基。

公开(公告)号：US5747518A

公开(公告)日：1998-05-05

申请号：US627929

申请日：1996-04-03

申请人： Yukihiro Yoshikawa ,  Kanji Tomiya ,  Hiroyuki Katsuta ,  Hideo Kawashima ,  Osamu Takahashi ,  Shunichi Inami ,  Yuji Yanase ,  Junro Kishi ,  Hitoshi Shimotori ,  Naofumi Tomura

发明人： Yukihiro Yoshikawa ,  Kanji Tomiya ,  Hiroyuki Katsuta ,  Hideo Kawashima ,  Osamu Takahashi ,  Shunichi Inami ,  Yuji Yanase ,  Junro Kishi ,  Hitoshi Shimotori ,  Naofumi Tomura

IPC分类号： A01N43/10 ,  A01N43/40 ,  A01N43/56 ,  A01N43/78 ,  C07D333/36 ,  C07D333/42 ,  C07D333/44 ,  C07D401/12 ,  C07D403/12 ,  C07D409/12 ,  C07D417/12 ,  A61K31/415 ,  A61K31/38 ,  A61K31/425 ,  A61K31/44

CPC分类号： C07D401/12 ,  A01N43/10 ,  A01N43/40 ,  A01N43/56 ,  A01N43/78 ,  C07D333/36 ,  C07D333/42 ,  C07D333/44 ,  C07D403/12 ,  C07D409/12 ,  C07D417/12

摘要： The substituted thiophene derivative of the invention which is represented by the general formula (1) has a broad disease spectrum for a pathogenic fungus of various crops, exhibits an excellent controlling effect on disease such as gray mold, powdery mildew and rust in particular, and is also effective for a resistant fungus of conventional fungicides which has become a serious problem, and consequently is useful for an agricultural and horticultural fungicide. ##STR1##

摘要翻译： 由通式（1）表示的本发明的取代噻吩衍生物对各种作物的致病真菌具有广泛的疾病谱，特别是对灰霉病，白粉病和锈病等疾病具有优异的防治效果， 对于已经成为严重问题的常规杀真菌剂的抗性真菌也是有效的，因此可用于农业和园艺杀真菌剂。 （1）

公开(公告)号：US5965774A

公开(公告)日：1999-10-12

申请号：US150170

申请日：1998-09-09

申请人： Yukihiro Yoshikawa ,  Kanji Tomiya ,  Naofumi Tomura ,  Hiroyuki Katsuta ,  Osamu Takahashi ,  Shunichi Inami ,  Yuji Yanase ,  Junro Kishi ,  Hideo Kawashima

发明人： Yukihiro Yoshikawa ,  Kanji Tomiya ,  Naofumi Tomura ,  Hiroyuki Katsuta ,  Osamu Takahashi ,  Shunichi Inami ,  Yuji Yanase ,  Junro Kishi ,  Hideo Kawashima

IPC分类号： C07D231/14 ,  A01N43/26 ,  A01N43/56 ,  A01N43/78 ,  C07C211/45 ,  C07D213/82 ,  C07D231/16 ,  C07D241/14 ,  C07D263/34 ,  C07D277/20 ,  C07D277/30 ,  C07D277/56 ,  C07D307/68 ,  C07D309/28 ,  C07D327/06 ,  C07D333/24

CPC分类号： A01N43/56 ,  A01N43/78 ,  C07C211/45 ,  C07D231/14 ,  C07D277/56

摘要： A substituted anilide derivative represented by the formula (2): ##STR1## wherein A and B are methyl, and X is a hydrogen atom. The substituted anilide can be used to prepare a substituted carboxanilide derivative that exhibits a disease control effect against Botrytis cinerea, Powdery mildew, Pyricularia oryzae of rice plant and other various plant diseases, is excellent in residual effect, has activity against strains that are resistant to conventional chemicals, is safe for crops, and thus is useful as a plant disease control agent.

摘要翻译： 由式（2）表示的取代的酰苯胺衍生物：其中A和B是甲基，X是氢原子。 取代的酰苯胺可用于制备对灰葡萄孢，白粉病，稻瘟病菌和其他各种植物病害具有疾病防治作用的取代羧酰苯胺衍生物，其残留效果优异，具有抗抗性的菌株的活性 常规化学品对作物是安全的，因此可用作植物病害防治剂。

公开(公告)号：US20080312184A1

公开(公告)日：2008-12-18

申请号：US11883352

申请日：2006-01-20

申请人： Syunichi Inami ,  Yuji Yanase

发明人： Syunichi Inami ,  Yuji Yanase

IPC分类号： A01N43/56 ,  A01N43/653 ,  A01N55/10 ,  A01N57/16 ,  A01N43/78 ,  A01P3/00 ,  A01N43/36 ,  A01N43/54 ,  A01N43/76 ,  A01N43/88

CPC分类号： A01N43/54 ,  A01N43/56 ,  A01N43/653 ,  A01N43/30 ,  A01N47/14 ,  A01N47/44 ,  A01N43/66 ,  A01N43/76 ,  A01N43/32 ,  A01N43/78 ,  A01N37/46 ,  A01N57/16 ,  A01N43/36 ,  A01N37/24 ,  A01N43/50 ,  A01N37/20 ,  A01N43/40 ,  A01N47/12 ,  A01N43/88 ,  A01N37/50 ,  A01N37/32 ,  A01N37/22 ,  A01N37/52 ,  A01N47/24 ,  A01N2300/00

摘要： The present invention is to provide a composition for preventing plant diseases which comprises at least Component I and Component II, is capable of obtaining a synergic effect that cannot be expected with each single component, is capable of markedly increasing a control effect in a much smaller amount of chemicals against various plant pathogens, and causes no phytotoxicity suffering.A composition for preventing plant diseases comprises Components I and II as active ingredients. The Component I is (RS)—N—[2-(1,3-dimethylbutyl)thiophen-3-yl]-1-methyl-3-tri fluoromethyl-1H-pyrazole-4-carboxamide. As the Component II, there can be exemplified, for example, tetraconazole, flutriafol, imibenconazole, triadimefon, simeconazole, oxpoconazole fumarate, prothioconazole, bupirimate, spiroxamine, metiram, dodine, anilazine, chlozolinate, oxycarboxin, ethaboxam, iprovalicarb, pyrazophos, fluoroimide, diflumetorim, fenhexamid, famoxadone, fenamidone, cyazofamid, zoxamide, cyflufenamid, boscalid, benthiavalicarb-isopropyl, picoxystrobin, pyraclostrobin, fluoxastrobin or dimoxystrobin.

摘要翻译： 本发明提供一种用于预防植物病害的组合物，其至少包含组分I和组分II，能够获得对于每种单一组分不能预期的协同作用，能够显着增加小得多的控制效果 对各种植物病原体的化学物质的量，并且不会产生植物毒性。 用于预防植物病害的组合物包含组分I和II作为活性成分。 组分I是（RS）-N- [2-（1,3-二甲基丁基）噻吩-3-基] -1-甲基-3-三氟甲基-1H-吡唑-4-甲酰胺。 作为组分II，可以列举例如四唑唑，氟利多醇，阿米芬唑，三唑酮，西康唑，富马酸氧唑考唑，丙硫菌唑，泛酸，螺噻胺，甲霉唑，十二烷，苯那嗪，氯洛他定，氧卡卡林，依巴唑星，异恶唑，吡唑磷，氟代酰亚胺， 二氟吗啉，芬己酰胺，恶唑酮，甲酰胺，环唑酰胺，唑酰胺，环丙沙芬，布洛沙利多，苦草酸，异丙基，吡肟菌酯，嘧菌酯，氟西汀或二恶灵。

公开(公告)号：US09185911B2

公开(公告)日：2015-11-17

申请号：US11883352

申请日：2006-01-20

申请人： Syunichi Inami ,  Yuji Yanase

发明人： Syunichi Inami ,  Yuji Yanase

IPC分类号： A01N43/56 ,  A01N43/653 ,  A01N55/10 ,  A01N43/54

CPC分类号： A01N43/54 ,  A01N43/56 ,  A01N43/653 ,  A01N43/30 ,  A01N47/14 ,  A01N47/44 ,  A01N43/66 ,  A01N43/76 ,  A01N43/32 ,  A01N43/78 ,  A01N37/46 ,  A01N57/16 ,  A01N43/36 ,  A01N37/24 ,  A01N43/50 ,  A01N37/20 ,  A01N43/40 ,  A01N47/12 ,  A01N43/88 ,  A01N37/50 ,  A01N37/32 ,  A01N37/22 ,  A01N37/52 ,  A01N47/24 ,  A01N2300/00

摘要： The present invention is to provide a composition for preventing plant diseases which comprises at least Component I and Component II, is capable of obtaining a synergic effect that cannot be expected with each single component, is capable of markedly increasing a control effect in a much smaller amount of chemicals against various plant pathogens, and causes no phytotoxicity suffering.A composition for preventing plant diseases comprises Components I and II as active ingredients. The Component I is (RS)—N-[2-(1,3-dimethylbutyl)thiophen-3-yl]-1-methyl-3-tri fluoromethyl-1H-pyrazole-4-carboxamide. As the Component II, there can be exemplified, for example, tetraconazole, flutriafol, imibenconazole, triadimefon, simeconazole, oxpoconazole fumarate, prothioconazole, bupirimate, spiroxamine, metiram, dodine, anilazine, chlozolinate, oxycarboxin, ethaboxam, iprovalicarb, pyrazophos, fluoroimide, diflumetorim, fenhexamid, famoxadone, fenamidone, cyazofamid, zoxamide, cyflufenamid, boscalid, benthiavalicarb-isopropyl, picoxystrobin, pyraclostrobin, fluoxastrobin or dimoxystrobin.

摘要翻译： 本发明提供一种用于预防植物病害的组合物，其至少包含组分I和组分II，能够获得对于每种单一组分不能预期的协同作用，能够显着增加小得多的控制效果 对各种植物病原体的化学物质的量，并且不会产生植物毒性。 用于预防植物病害的组合物包含组分I和II作为活性成分。 组分I是（RS）-N- [2-（1,3-二甲基丁基）噻吩-3-基] -1-甲基-3-三氟甲基-1H-吡唑-4-甲酰胺。 作为组分II，可以列举例如四唑唑，氟利多醇，阿米芬唑，三唑酮，西康唑，富马酸氧唑考唑，丙硫菌唑，泛酸，螺噻胺，甲霉唑，十二烷，苯那嗪，氯洛他定，氧卡卡林，依巴唑星，异恶唑，吡唑磷，氟代酰亚胺， 二氟吗啉，芬己酰胺，恶唑酮，甲酰胺，环唑酰胺，唑酰胺，环丙沙芬，布洛沙利多，苦草酸，异丙基，吡肟菌酯，嘧菌酯，氟西汀或二恶灵。

公开(公告)号：US20060235066A1

公开(公告)日：2006-10-19

申请号：US10564851

申请日：2004-07-07

申请人： Koichi Morinaga ,  Yuji Yanase ,  Kanemitsu Miyama ,  Hideo Kawashima

发明人： Koichi Morinaga ,  Yuji Yanase ,  Kanemitsu Miyama ,  Hideo Kawashima

IPC分类号： A01N43/56

CPC分类号： A01N43/56 ,  A01N25/24 ,  A01N25/30 ,  A01N25/04 ,  A01N2300/00

摘要： The present invention provides an aqueous suspension formulation containing (RS)—N-[2-(1,3-dimethylbutyl)thiophene-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide and having high rain resistance and stable residual effectiveness. A aqueous suspension formulation for foliar application fungicide of the present invention contains a fungicidal active ingredient, (RS)—N-[2-(1,3-dimethylbutyl)thiophene-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide, and a polyoxyalkylene rosin acid ester or liquid paraffin, and has improved rain resistance on plant leaves and excellent residual effectiveness.

摘要翻译： 本发明提供含有（RS）-N- [2-（1,3-二甲基丁基）噻吩-3-基] -1-甲基-3-三氟甲基-1H-吡唑-4-甲酰胺并含有高 耐雨性和稳定的残留效果。 本发明的叶面施用杀真菌剂的水性悬浮液制剂含有杀真菌活性成分（RS）-N- [2-（1,3-二甲基丁基）噻吩-3-基] -1-甲基-3-三氟甲基-1H- - 吡唑-4-甲酰胺和聚氧化烯松香酸酯或液体石蜡，并且具有改善植物叶子的耐雨性和优异的残留效果。