公开(公告)号：US20240383875A1

公开(公告)日：2024-11-21

申请号：US18777339

申请日：2024-07-18

Applicant: Hoffmann-La Roche Inc.

Inventor： Mahendra AWALE ,  Stefan BERCHTOLD ,  Julie CHARPENTIER ,  Héloïse Marie Albine COLOMBANO ,  Guillaume DECORET ,  Katrin GROEBKE ZBINDEN ,  Nicole GROSSMANN ,  Wolfgang HAAP ,  Philip Anthony HARRIS ,  Jérôme HERT ,  Jonah Milton KALLENBACH ,  Christian KRAMER ,  Lukas KREIS ,  Danny KRUMM ,  Xavier LUCAS CABRE ,  Nenad MANEVSKI ,  Philippe PFLIEGER ,  Amir Mohsen POURMOUSA ABKENAR ,  Etienne RAUBER ,  Dazhi TAN ,  Jean-Yves WACH ,  Roger WERMUTH

IPC: C07D401/14 ,  A61K9/00 ,  A61K9/20 ,  A61K9/28 ,  A61K9/48 ,  A61K31/4439 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/497 ,  A61K31/501 ,  A61K31/506 ,  A61K31/53 ,  A61K31/5377 ,  A61K31/538 ,  A61K47/10 ,  A61K47/12 ,  C07D401/04 ,  C07D405/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D491/107 ,  C07D498/04

Abstract: The invention relates to a compound of formula (I) wherein A1, A2, A3, R1, R2, R2′, R3, R4 and R5 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.

公开(公告)号：US20230227411A1

公开(公告)日：2023-07-20

申请号：US17996323

申请日：2021-04-14

Applicant: Hoffmann-La Roche Inc.

Inventor： Guido GALLEY ,  Katrin GROEBKE ZBINDEN ,  Daniel HUNZIKER ,  Wolfgang GUBA ,  Danny KRUMM ,  Daniela KRUMMENACHER ,  Manuel HILBERT

IPC: C07D235/06 ,  C07D401/06

CPC classification number: C07D235/06 ,  C07D401/06

Abstract: The invention relates to a compound of formula (I) wherein R1-R3 are as defined in the description and in the claims The compound of formula (I) can be used as a medicament.

公开(公告)号：US20230192631A1

公开(公告)日：2023-06-22

申请号：US17996325

申请日：2021-04-14

Applicant: Hoffmann-La Roche Inc.

Inventor： Stefan BERCHTOLD ,  Guido GALLEY ,  Katrin GROEBKE ZBINDEN ,  Wolfgang GUBA ,  Daniel HUNZIKER ,  Danny KRUMM

IPC: C07D249/08 ,  C07D239/36 ,  C07D295/145 ,  C07C233/55 ,  C07D233/60 ,  C07C65/21

CPC classification number: C07D249/08 ,  C07D239/36 ,  C07D295/145 ,  C07C233/55 ,  C07D233/60 ,  C07C65/21

Abstract: The invention relates to a compound of formula (I) wherein R1—R3 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.

公开(公告)号：US20230348398A1

公开(公告)日：2023-11-02

申请号：US17996321

申请日：2021-04-14

Applicant: Hoffmann-La Roche Inc.

Inventor： Guido GALLEY ,  Katrin GROEBKE ZBINDEN ,  Daniel HUNZIKER ,  Wolfgang GUBA ,  Stefan BERCHTOLD ,  Danny KRUMM ,  Daniela KRUMMENACHER ,  Manuel HILBERT

IPC: C07D235/08 ,  C07D235/30 ,  C07D235/10 ,  C07D235/14 ,  C07D401/06 ,  C07D403/06

CPC classification number: C07D235/08 ,  C07D235/30 ,  C07D235/10 ,  C07D235/14 ,  C07D401/06 ,  C07D403/06

Abstract: The invention relates to a compound of formula (I) wherein R1-R4 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.

公开(公告)号：US20230219913A1

公开(公告)日：2023-07-13

申请号：US17996328

申请日：2021-04-14

Applicant: Hoffmann-La Roche Inc.

Inventor： Stefan BERCHTOLD ,  Guido GALLEY ,  Katrin GROEBKE ZBINDEN ,  Wolfgang GUBA ,  Danny KRUMM

IPC: C07D285/16 ,  C07D417/06

CPC classification number: C07D285/16 ,  C07D417/06

Abstract: The invention relates to a compound of formula (I) wherein R1-R3 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.