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公开(公告)号：US20120123262A1
公开(公告)日：2012-05-17
申请号：US13379741
申请日：2010-06-30
IPC分类号： A61B8/00
CPC分类号： A61B8/00 , A61B5/0048 , A61B5/0051 , A61B8/085 , A61B8/485 , A61B8/5223 , G01S7/52022
摘要： Shear Wave Dispersion Vibrometry (SDUV) is performed such that, after a single instance of their push pulse (218), a plurality of tracking pulses (222) are issued to sample, more than once, each of a plurality of locations (120, 148) on an associated monochromatic shear wave (116) in sampling that at least one of scans the plural locations in separate passes and, with a pulse of the plural tracking pulses, samples multiple ones of the plural locations concurrently. In a supplementary aspect, phase difference, for a given moment, is determined by taking into account intersample delay (156), if the determination relies on samples that are taken at different times.
摘要翻译： 执行剪切波分散振动波谱（SDUV），使得在其单次推送脉冲（218）之后，发出多个跟踪脉冲（222）以多次采样多个位置（120,120）中的每一个， 148）在相关联的单色剪切波（116）上进行采样，以便在单独的通过中的多个位置的扫描中的至少一个并且多个跟踪脉冲中的脉冲同时对多个位置中的多个位置进行采样。 在补充方面，如果确定依赖于在不同时间拍摄的样本，则通过考虑采样间延迟（156）来确定给定时刻的相位差。
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公开(公告)号：US09125547B2
公开(公告)日：2015-09-08
申请号：US13379741
申请日：2010-06-23
CPC分类号： A61B8/00 , A61B5/0048 , A61B5/0051 , A61B8/085 , A61B8/485 , A61B8/5223 , G01S7/52022
摘要： Shear Wave Dispersion Vibrometry (SDUV) is performed such that, after a single instance of their push pulse (218), a plurality of tracking pulses (222) are issued to sample, more than once, each of a plurality of locations (120, 148) on an associated monochromatic shear wave (116) in sampling that at least one of scans the plural locations in separate passes and, with a pulse of the plural tracking pulses, samples multiple ones of the plural locations concurrently. In a supplementary aspect, phase difference, for a given moment, is determined by taking into account intersample delay (156), if the determination relies on samples that are taken at different times.
摘要翻译： 执行剪切波分散振动波谱（SDUV），使得在其单次推送脉冲（218）之后，发出多个跟踪脉冲（222）以多次采样多个位置（120,120）中的每一个， 148）在相关联的单色剪切波（116）上进行采样，以便在单独的通过中的多个位置的扫描中的至少一个并且多个跟踪脉冲中的脉冲同时对多个位置中的多个位置进行采样。 在补充方面，如果确定依赖于在不同时间拍摄的样本，则通过考虑采样间延迟（156）来确定给定时刻的相位差。
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公开(公告)号：US08734352B2
公开(公告)日：2014-05-27
申请号：US13383471
申请日：2010-06-23
IPC分类号： A61B8/00
CPC分类号： A61B8/00 , A61B5/0048 , A61B8/485 , G01S7/52042
摘要： Shear wave dispersion ultrasound vibrometry (SDUV) is implemented in some embodiments to form, from a single tracking pulse, in-parallel-directed receive lines (411-426) for making measurements of a monochromatic shear wave. In some embodiments, sampling is performed, over spatial locations by means of passes over the locations, in an interlaced pattern (600) for making measurements of the wave. In some embodiments, measurements are made of the wave and to the measurements are applied a bank of filters (S724) that are tuned to respective candidate wave speeds, all without the need to determine a difference between wave phases at different spatial locations (451-454).
摘要翻译： 在一些实施例中实施剪切波分散超声波振动测量（SDUV），以从单个跟踪脉冲形成用于进行单色剪切波的测量的并行导向的接收线（411-426）。 在一些实施例中，通过在位置上的通过在隔行扫描图案（600）中通过空间位置进行采样，以进行波的测量。 在一些实施例中，对波进行测量，并且将测量值应用于被调谐到各个候选波速的滤波器组（S724），全部不需要确定不同空间位置处的波相位之间的差（451- 454）。
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公开(公告)号：US20120116220A1
公开(公告)日：2012-05-10
申请号：US13383471
申请日：2010-06-23
IPC分类号： A61B8/00
CPC分类号： A61B8/00 , A61B5/0048 , A61B8/485 , G01S7/52042
摘要： Shear wave dispersion ultrasound vibrometry (SDUV) is implemented in some embodiments to form, from a single tracking pulse, in-parallel-directed receive lines (411-426) for making measurements of a monochromatic shear wave. In some embodiments, sampling is performed, over spatial locations by means of passes over the locations, in an interlaced pattern (600) for making measurements of the wave. In some embodiments, measurements are made of the wave and to the measurements are applied a bank of filters (S724) that are tuned to respective candidate wave speeds, all without the need to determine a difference between wave phases at different spatial locations (451-454).
摘要翻译： 在一些实施例中实施剪切波分散超声波振动测量（SDUV），以从单个跟踪脉冲形成用于进行单色剪切波的测量的并行导向的接收线（411-426）。 在一些实施例中，通过在位置上的通过在隔行扫描图案（600）中通过空间位置进行采样，以进行波的测量。 在一些实施例中，对波进行测量，并且将测量值应用于被调谐到各个候选波速的滤波器组（S724），全部不需要确定不同空间位置处的波相位之间的差（451- 454）。
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公开(公告)号：US20130131511A1
公开(公告)日：2013-05-23
申请号：US13511307
申请日：2010-11-15
申请人： Roy Beck Peterson , Yan Shi , Hua Xie , Jean-Luc Robert , Vijay Shamdasani , Robert Randall Entrekin , Anna Teresa Fernandez
发明人： Roy Beck Peterson , Yan Shi , Hua Xie , Jean-Luc Robert , Vijay Shamdasani , Robert Randall Entrekin , Anna Teresa Fernandez
CPC分类号： A61B8/485 , A61B5/0048 , A61B8/08 , A61B8/085 , A61B8/14 , A61B8/463 , A61B8/5223 , G01S7/52022 , G01S7/52042 , G01S7/52071 , G01S7/52095 , G01S15/8984
摘要： An ultrasonic diagnostic imaging system produces an image of shear wave velocities by transmitting push pulses to generate shear waves. A plurality of tracking lines are transmitted and echoes received by a focusing beamformer adjacent to the location of the push pulses. The tracking lines are sampled in a time-interleaved manner. The echo data acquired along each tracking line is processed to determine the time of peak tissue displacement caused by the shear waves at points along the tracking line, and the times of peaks at adjacent tracking lines compared to compute a local shear wave velocity. The resultant map of shear wave velocity values is color-coded and displayed over an anatomical image of the region of interest.
摘要翻译： 超声波诊断成像系统通过传递推动脉冲来产生剪切波速度的图像以产生剪切波。 多个跟踪线被发送，并且由聚焦波束形成器接收的与推送脉冲位置相邻的回波。 跟踪线以时间交织的方式进行采样。 处理沿着每个跟踪线获取的回波数据，以确定由沿着跟踪线的点处的剪切波引起的峰组织位移的时间，以及相邻跟踪线的峰值时间，以计算局部剪切波速度。 所得到的剪切波速度值的映射是彩色编码的，并显示在感兴趣区域的解剖图像上。
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公开(公告)号：US10368843B2
公开(公告)日：2019-08-06
申请号：US13511307
申请日：2010-11-15
申请人： Roy Beck Peterson , Yan Shi , Hua Xie , Jean-Luc Robert , Vijay Shamdasani , Robert Randall Entrekin , Anna Teresa Ferandez
发明人： Roy Beck Peterson , Yan Shi , Hua Xie , Jean-Luc Robert , Vijay Shamdasani , Robert Randall Entrekin , Anna Teresa Ferandez
摘要： An ultrasonic diagnostic imaging system produces an image of shear wave velocities by transmitting push pulses to generate shear waves. A plurality of tracking lines are transmitted and echoes received by a focusing beamformer adjacent to the location of the push pulses. The tracking lines are sampled in a time-interleaved manner. The echo data acquired along each tracking line is processed to determine the time of peak tissue displacement caused by the shear waves at points along the tracking line, and the times of peaks at adjacent tracking lines compared to compute a local shear wave velocity. The resultant map of shear wave velocity values is color-coded and displayed over an anatomical image of the region of interest.
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公开(公告)号：US20130317362A1
公开(公告)日：2013-11-28
申请号：US13995522
申请日：2011-12-19
申请人： Yan Shi , Hua Xie , Roy Peterson , Jean-Luc Robert , Vijay Shamdasani
发明人： Yan Shi , Hua Xie , Roy Peterson , Jean-Luc Robert , Vijay Shamdasani
CPC分类号： A61B8/5207 , A61B5/0051 , A61B5/055 , A61B5/4244 , A61B5/7235 , A61B8/4483 , A61B8/485 , A61B2562/0204
摘要： The weighted-average-based position (244) in the temporal domain is computed based on the sampling of shear wave displacement (226) along the propagation path. The weighting is, for example, by displacement observed at times (230) corresponding to sampling and represents the time of arrival of the shear wave at the shear-wave propagation path location being sampled. In some embodiments, the computed shear-wave times of arrival at respective locations are functionally related to known inter-location distances (250) to derive shear-wave group velocity. The derived velocity can serve as input into known algorithms for estimating shear elasticity of the medium, such as body tissue, for purposes of clinical diagnosis and therapy assessment.
摘要翻译： 基于沿着传播路径的剪切波位移（226）的采样来计算时域中的基于加权平均的位置（244）。 加权是例如通过对应于采样的时间（230）观察到的位移，并且表示剪切波在被采样的剪切波传播路径位置处的到达时间。 在一些实施例中，到达相应位置的计算的剪切波时间在功能上与已知位置间距（250）有关，以导出剪切波群速度。 为了临床诊断和治疗评估的目的，导出的速度可以用作用于估计介质（例如身体组织）的剪切弹性的已知算法的输入。
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8.发明申请ADJUSTING MEASUREMENTS OF THE EFFECTS OF ACOUSTIC RADIATION FORCE FOR BACKGROUND MOTION EFFECTS 审中-公开调节声辐射力对背景运动影响的影响的测量公开(公告)号：US20130296698A1
公开(公告)日：2013-11-07
申请号：US13990201
申请日：2011-12-08
申请人： John Douglas Fraser , Hua Xie
发明人： John Douglas Fraser , Hua Xie
IPC分类号： A61B8/08
CPC分类号： A61B8/485 , A61B8/0825 , A61B8/4488 , A61B8/5276 , G01S7/52036 , G01S7/52042 , G01S7/5205 , G01S7/52095 , G01S15/8925
摘要： An ultrasonic diagnostic imaging system for shear wave measurement transmits push pulses into tissue for the generation of shear waves. Characteristics of the shear waves such as their velocity of passage through the tissue are measured to assess properties such as tissue stiffness. The measurements are compensated for effects of background motion by sampling echo signals from the tissue at different times and comparing the samples to detect the presence of relative motion between the ultrasound probe and the region of interest where shear waves are detected. Sensed background motion is used to adjust measured shear wave characteristics.
摘要翻译： 用于剪切波测量的超声波诊断成像系统将推入脉冲传送到组织中以产生剪切波。 测量剪切波的特征，例如通过组织的速度，以评估组织刚度等性质。 通过在不同时间对来自组织的回波信号进行采样来对背景运动的影响进行补偿，并比较样本以检测超声探头与检测到剪切波的感兴趣区域之间的相对运动的存在。 感测背景运动用于调整测量的剪切波特性。
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公开(公告)号：US20090263610A1
公开(公告)日：2009-10-22
申请号：US12357366
申请日：2009-01-21
IPC分类号： B32B3/00
CPC分类号： A47B13/08 , A47B96/206 , Y10T428/17 , Y10T428/19 , Y10T428/195
摘要： Glue-laminated bamboo furniture articles include a main panel (1) and plural panel supports (2). The panel (1) includes a main framework (11), a main plate (12) disposed on the main framework (11) and outer framework (13) covering the main framework (11). The main framework (11) is formed by joining corresponding ends of a plurality of frame borders (111). The main plate (12) corresponds in shape to a plane enclosed by the main framework (11) and includes slopes on interfacial edges (121) thereof. The outer framework (13) is formed by joining corresponding ends of sealing plates (131). Sloped upper ends (1311) of the sealing plates match the slopes on the interfacial edges (121) of the main plate (12). The resulting gluelam bamboo furniture has a trim aesthetic appearance, exhibits the beautiful natural texture of bamboo, effectively prevents the furniture from warping, has great durability, conserves materials and effectively reduces production costs.
摘要翻译： 胶合层压竹家具制品包括主面板（1）和多个面板支架（2）。 面板（1）包括主框架（11），设置在主框架（11）上的主板（12）和覆盖主框架（11）的外框架（13）。 主框架（11）通过连接多个框架边框（111）的对应端部而形成。 主板（12）的形状对应于由主框架（11）包围的平面，并且在其平面边缘（121）上包括斜面。 外框架（13）通过连接密封板（131）的相应端部而形成。 密封板的倾斜上端（1311）与主板（12）的界面边缘（121）上的斜面相匹配。 所生产的胶棉竹家具具有美观的外观，呈现竹子美丽的自然纹理，有效防止家具翘曲，耐用性强，节约材料，有效降低生产成本。
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公开(公告)号：US20090011043A1
公开(公告)日：2009-01-08
申请号：US12167082
申请日：2008-07-02
申请人： Hua Xie
发明人： Hua Xie
CPC分类号： A61K35/14
摘要： Disclosed are tissue sealants that include whole blood and an effective amount of an exogenous protein cross-linker to cross-link the whole blood. Also disclosed are methods for forming a tissue sealant. Such methods include, providing whole blood and mixing the whole blood with an effective amount of an exogenous protein cross-linker to cross-link the whole blood into an adherent mass, thereby forming the tissue sealant. The disclosed tissue sealants can be used for any application, for example to achieve hemostasis, bond tissue of a subject and/or or seal a fluid or gas leak in a tissue of a subject.
摘要翻译： 公开了包含全血的组织密封剂和有效量的外源蛋白质交联剂以交联全血。 还公开了用于形成组织密封剂的方法。 这样的方法包括提供全血并将全血与有效量的外源蛋白质交联剂混合以将全血交联成粘附物质，从而形成组织密封剂。 所公开的组织密封剂可以用于任何应用，例如用于实现止血，受试者的粘合组织和/或密封受试者组织中的流体或气体泄漏。
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