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    Probe for implantable electro-stimulation device
    1.
    发明授权
    Probe for implantable electro-stimulation device 有权
    探针用于植入式电刺激装置

    公开(公告)号：US09421359B2

    公开(公告)日：2016-08-23

    申请号：US13120758

    申请日：2009-10-07

    申请人： Ke Wang ,  Hubert Cecile Francois Martens ,  Franciscus Paulus Maria Budzelaar ,  Dirk Willem Harberts ,  Michael Marcel Jose Decre ,  Jeroen Jacob Arnold Tol

    发明人： Ke Wang ,  Hubert Cecile Francois Martens ,  Franciscus Paulus Maria Budzelaar ,  Dirk Willem Harberts ,  Michael Marcel Jose Decre ,  Jeroen Jacob Arnold Tol

    IPC分类号： A61N1/05 ,  H05K9/00 ,  A61N1/08

    CPC分类号： A61N1/05 ,  A61N1/0529 ,  A61N1/0531 ,  A61N1/0551 ,  A61N1/056 ,  A61N1/086 ,  H05K9/002

    摘要： The invention relates to a probe for an implantable electro-stimulation device. The probe (20) has a distal end (12) and a proximal end (13), and moreover comprises: one or more electrodes (11) a shield (21) of conducting material covering a major part of the probe, said shield extending from the vicinity of at least one of the one or more electrodes (11) towards the proximal end (13) or towards the distal end (12) of the probe (20); and a layer (22a, 22b) of insulating material covering part of the shield (21) in the vicinity of the at least one of the one or more electrodes. The shield protects wires (14), extending from electrodes to the proximal end of the probe, from undesired interference of external RF fields. The exposed part of the shield not covered by the layer of insulating material serves as a return electrode for the electrostimulation signal path.

    摘要翻译： 本发明涉及可植入电刺激装置的探针。 探针（20）具有远端（12）和近端（13），并且还包括：一个或多个电极（11）覆盖探针的主要部分的导电材料的屏蔽件（21），所述屏蔽件延伸 从所述一个或多个电极（11）中的至少一个朝向所述近端（13）或所述探针（20）的远端（12）的附近; 以及覆盖所述一个或多个电极中的至少一个电极附近的所述屏蔽体（21）的一部分的绝缘材料层（22a，22b）。 屏蔽保护从电极延伸到探针近端的电线（14）免受外部RF场的不期望的干扰。 未被绝缘材料层覆盖的屏蔽件的暴露部分用作电刺激信号路径的返回电极。

    Apparatus with wireless communication module
    2.
    发明授权
    Apparatus with wireless communication module 有权
    无线通信模块设备

    公开(公告)号：US09259592B2

    公开(公告)日：2016-02-16

    申请号：US13119038

    申请日：2009-09-17

    申请人： Jacobus Josephus Leijssen ,  Hubert Cecile Francois Martens ,  Michael Marcel Jose Decre ,  Jeroen Jacob Arnold Tol

    发明人： Jacobus Josephus Leijssen ,  Hubert Cecile Francois Martens ,  Michael Marcel Jose Decre ,  Jeroen Jacob Arnold Tol

    IPC分类号： H02J7/00 ,  A61N1/378 ,  A61N1/36 ,  A61N1/372 ,  A61N1/00 ,  A61N1/05

    CPC分类号： A61N1/3787 ,  A61N1/00 ,  A61N1/0529 ,  A61N1/0534 ,  A61N1/36082 ,  A61N1/37276

    摘要： The invention relates to an electronic apparatus (100) comprising a charging module (20) for receiving external energy (RF1) and for transferring it to a rechargeable energy storage (10) in a “charging state”. Moreover, the apparatus comprises a processing module which can be operated in a working state that is enabled if the charging module (20) is in the charging state and the apparatus is in a standard operating mode. The processing module may for example be a communication module (30) that can communicate wirelessly in its working state. In the standard operating mode, communication with the apparatus (100) is thus only possible if the apparatus (100) is simultaneously charged. The communication module (30) can therefore be completely switched off during the residual time, thus reducing power consumption and avoiding erroneous communication or misuse.

    摘要翻译： 本发明涉及一种电子设备（100），包括用于接收外部能量（RF1）的充电模块（20）并将其传送到“充电状态”的可再充电能量存储器（10）。 此外，该装置包括处理模块，其可以在充电模块（20）处于充电状态并且该装置处于标准操作模式的情况下工作的工作状态下工作。 处理模块可以例如是可以在其工作状态下以无线方式通信的通信模块（30）。 在标准操作模式下，如果设备（100）同时充电，则与设备（100）的通信是可能的。 因此，通信模块（30）可以在剩余时间内完全关闭，从而降低功耗并避免错误的通信或误用。

    Connector with a surface with primary and reduntant connection points
    3.
    发明授权
    Connector with a surface with primary and reduntant connection points 有权
    连接器与表面具有主要和连接点

    公开(公告)号：US08297997B2

    公开(公告)日：2012-10-30

    申请号：US13126361

    申请日：2009-11-09

    申请人： Hubert Cecile Francois Martens

    发明人： Hubert Cecile Francois Martens

    IPC分类号： H01R13/28

    CPC分类号： A61N1/3752 ,  H01R12/75 ,  H01R2107/00 ,  H01R2201/12

    摘要： A connector (10, 30, 40) is provided for coupling an electronic circuit (11) of an electronic device to sensor and/or actuation elements (12) of the electronic device. The connector (10, 30, 40) comprises at least one connection surface (21) with i connection points (13), the i connection points (13) comprise j primary connection points (13) for coupling the electronic circuit (11) to j corresponding ones of the elements (12), and k redundant connection points (13) for redundantly coupling the electronic circuit (11) to at least one of the elements (12). The primary and the redundant connection points (13) for the at least one of the elements (12) are distributed over the connection surface (21).

    摘要翻译： 提供连接器（10,30,40），用于将电子设备的电子电路（11）耦合到电子设备的传感器和/或致动元件（12）。 连接器（10,30,40）包括具有i个连接点（13）的至少一个连接表面（21），i个连接点（13）包括j个主要连接点（13），用于将电子电路（11）耦合到 j个对应的元件（12）和k个用于将电子电路（11）冗余地耦合到元件（12）中的至少一个的冗余连接点（13）。 元件（12）中的至少一个元件的主要和冗余连接点（13）分布在连接表面（21）上。

    Planning System for Neurostimulation Therapy
    4.
    发明申请
    Planning System for Neurostimulation Therapy 有权
    神经刺激治疗计划系统

    公开(公告)号：US20120109599A1

    公开(公告)日：2012-05-03

    申请号：US13285136

    申请日：2011-10-31

    申请人： Hubert Cecile Francois Martens

    发明人： Hubert Cecile Francois Martens

    IPC分类号： G06F7/60

    CPC分类号： A61N1/37247 ,  A61N1/00

    摘要： A system for planning implantation of a neurostimulation probe is provided. The system comprises an input for receiving anatomical data comprising information regarding a position and an orientation of at least one fiber bundle in a target region, an input for receiving therapeutic information comprising information regarding a stimulation preferability of the at least one fiber bundle, an optimization module for based on the position, the orientation and the stimulation preferability of the at least one fiber bundle calculating at least one optimal position and at least one optimal orientation for implantation of the neurostimulation probe at which optimal position and orientation the probe is capable of generating an electric field gradient substantially parallel to at least one fiber bundle with a high stimulation preferability and/or substantially perpendicular to at least one fiber bundle with a low stimulation preferability and an output for providing the optimal position and orientation.

    摘要翻译： 提供了一种用于规划神经刺激探针植入的系统。 该系统包括用于接收包括关于目标区域中的至少一个纤维束的位置和取向的信息的解剖数据的输入，用于接收包括关于至少一个纤维束的刺激优选性的信息的治疗信息的输入，优化 模块，用于基于所述至少一个纤维束的位置，方向和刺激优选性计算至少一个最佳位置和至少一个用于植入神经刺激探针的最佳取向，其中探针能够产生最佳位置和取向 基本平行于具有高刺激优选性和/或基本垂直于具有低刺激优选性的至少一个纤维束的至少一个纤维束的电场梯度和用于提供最佳位置和取向的输出。

    FIRST TIME RIGHT PLACEMENT OF A DBS LEAD
    6.
    发明申请
    FIRST TIME RIGHT PLACEMENT OF A DBS LEAD 有权
    第一时间放置星巴斯领导

    公开(公告)号：US20100036468A1

    公开(公告)日：2010-02-11

    申请号：US12518158

    申请日：2007-11-16

    申请人： Michael Marcel Jose Decre ,  Hubert Cecile Francois Martens

    发明人： Michael Marcel Jose Decre ,  Hubert Cecile Francois Martens

    IPC分类号： A61N1/00 ,  A61B5/00

    CPC分类号： A61N1/36139 ,  A61N1/05 ,  A61N1/0529 ,  A61N1/0534 ,  A61N1/3605 ,  A61N1/3606 ,  A61N1/36082 ,  A61N1/36185

    摘要： The disclosure is directed to a deep brain stimulation (DBS) lead having a distal end for providing therapeutic electrical stimulation to tissue in a stimulation target area of a patient's brain, comprising an array of one or more stimulation elements and sensing elements located at the distal end of the lead; each of the one or more stimulation elements is capable of providing electrical stimulation to the brain tissue in the target area; and each of the one or more sensing elements is capable of detecting electrical signals produced by nerve cells within the brain; wherein after the first implantation of the lead into the brain along a trajectory that is pre-determined by non-surgical procedures, the array of stimulation and sensing elements is capable of facilitating the location of the target area and the determination for each of the stimulation elements of the required stimulation parameters needed to provide the therapeutic stimulation to the brain tissue in the stimulation target area, without requiring any additional implantations of the lead after the first implantation. A stimulation system including the DBS lead and a pulse generator is disclosed. Also disclosed is a method of providing therapeutic DBS to brain tissue using the lead.

    摘要翻译： 本公开涉及具有远端的深部脑刺激（DBS）引线，其用于向患者的大脑的刺激目标区域中的组织提供治疗性电刺激，包括一个或多个刺激元件的阵列和位于远端的感测元件 领先的结束 所述一个或多个刺激元件中的每一个能够向目标区域中的脑组织提供电刺激; 并且所述一个或多个感测元件中的每一个能够检测由脑内的神经细胞产生的电信号; 其中在沿着通过非外科手术预先确定的轨迹将引线首次植入脑中之后，刺激和感测元件的阵列能够促进目标区域的位置和每个刺激的确定 为了在刺激目标区域中的脑组织提供治疗刺激所需的刺激参数的要素，而不需要在第一次植入之后再进行铅的注入。 公开了包括DBS引线和脉冲发生器的刺激系统。 还公开了使用铅向脑组织提供治疗性DBS的方法。

    Optical Disc Having Combined Rom/R Area
    8.
    发明申请
    Optical Disc Having Combined Rom/R Area 审中-公开
    结合Rom / R区域的光盘

    公开(公告)号：US20080259759A1

    公开(公告)日：2008-10-23

    申请号：US10597565

    申请日：2005-01-28

    申请人： Hubert Cecile Francois Martens ,  Ruud Vlutters

    发明人： Hubert Cecile Francois Martens ,  Ruud Vlutters

    IPC分类号： G11B3/74 ,  G11B7/00

    CPC分类号： G11B7/24085 ,  G11B7/004 ,  G11B7/0079 ,  G11B7/14 ,  G11B7/24038

    摘要： A record carrier has information represented by high density read-only marks in a track. The read-only marks (74,75) are optically readable according to a predefined high-density data format such as CD or DVD via a beam of radiation by first variations of the radiation. The record carrier has a recordable layer (70) for writing recorded marks (72,73) in a recording area of the record carrier, which recording area extends over the track (9) carrying the read-only marks. The recordable layer (70) is arranged to generate second variations of the radiation by a difference between an unrecorded state and a recorded state. A recording device writes recorded marks on top of the read-only marks. A read device recovers the first and second variations, and detects the read-only marks and the recorded marks from a same part of the track.

    摘要翻译： 记录载体具有由轨道中的高密度只读标记表示的信息。 根据预定的高密度数据格式（例如CD或DVD），通过辐射的第一变化经由辐射束，只读标记（74,75）是光学可读的。 记录载体具有用于在记录载体的记录区域中写入记录标记（72,73）的记录层（70），该记录区域在承载只读标记的轨道（9）上延伸。 可记录层（70）被布置成通过未记录状态和记录状态之间的差异来产生辐射的第二变化。 记录装置将记录标记写在只读标记之上。 读取装置恢复第一和第二变化，并且从轨道的相同部分检测只读标记和记录标记。

    Method and system for determining a threshold for spike detection of electrophysiological signals
    10.
    发明授权
    Method and system for determining a threshold for spike detection of electrophysiological signals 有权
    用于确定电生​​理信号的尖峰检测阈值的方法和系统

    公开(公告)号：US09202114B2

    公开(公告)日：2015-12-01

    申请号：US12993260

    申请日：2009-05-25

    申请人： Kevin T. Dolan ,  Hubert Cecile Francois Martens

    发明人： Kevin T. Dolan ,  Hubert Cecile Francois Martens

    IPC分类号： G06F19/00 ,  G06K9/00

    CPC分类号： G06K9/0053

    摘要： A method is provided for determining a threshold (81, 82) for spike (12) detection in an electrophysiological signal (11). The method comprises a step of determining an estimated envelope (31) of the electrophysiological signal (11), a step of, based on the estimated envelope (31), determining an estimated Gaussian noise, a step of determining a distribution (51) of instantaneous amplitudes of the estimated Gaussian noise, a step of determining a mode (61) of the distribution (51) of instantaneous amplitudes, and determining the threshold (81, 82) based on the mode (61) of the distribution (51) of instantaneous amplitudes.

    摘要翻译： 提供一种用于确定用于电生理信号（11）中的尖峰（12）检测的阈值（81,82）的方法。 该方法包括确定电生理信号（11）的估计包络（31）的步骤，基于估计包络（31），确定估计的高斯噪声的步骤，确定分布的分布（51）的步骤 估计高斯噪声的瞬时幅度，确定瞬时幅度分布（51）的模式（61）的步骤，以及基于分布（51）的模式（61）确定阈值（81,82） 瞬时振幅。