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公开(公告)号：US5980504A
公开(公告)日：1999-11-09
申请号：US881527
申请日：1997-06-24
申请人： Hugh J. Sharkey , John Ashley , Joel Saal , Jeffrey Saal , Le Trong Le
发明人： Hugh J. Sharkey , John Ashley , Joel Saal , Jeffrey Saal , Le Trong Le
IPC分类号： A61B17/00 , A61B17/16 , A61B17/22 , A61B17/28 , A61B17/32 , A61B17/34 , A61B17/88 , A61B18/00 , A61B18/04 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/24 , A61B19/00 , A61F2/30 , A61F2/44 , A61F7/02 , A61M1/00 , A61M25/00 , A61M25/01 , A61M25/09 , A61N1/06 , A61N1/40 , A61M31/00
CPC分类号： A61B17/1671 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/082 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61M25/0133 , A61N1/06 , A61N1/40 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/320016 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B18/14 , A61B18/18 , A61B18/24 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61B34/20 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09
摘要： An externally guidable intervertebral disc apparatus manipulates disc tissue present at a selected location of an intervertebral disc, comprising a catheter having a distal end, a proximal end, and a longitudinal axis, the catheter having an intradiscal section at the distal end of the catheter, the intradiscal section being extendible into the disc, having sufficient rigidity to be advanceable through the nucleus pulposus of the disc under a force applied longitudinally to the proximal end, having sufficient flexibility in a direction of the disc plane to be compliant with the inner wall, having insufficient penetration ability to be advanceable through the inner wall of the annulus fibrosus under the applied force; and a functional element located in the intradiscal section for adding or removing energy or a material at the selected location of the disc. Methods of using the apparatus are also disclosed.
摘要翻译： 外部可导向的椎间盘装置操作存在于椎间盘的选定位置处的椎间盘组织，其包括具有远端，近端和纵向轴线的导管，所述导管在导管的远端处具有椎间盘内部分， 椎间盘内部分可延伸到椎间盘中，具有足够的刚性，以在纵向施加到近端的力的作用下通过盘的髓核推进，在盘平面的方向上具有足够的柔性以与内壁相一致， 在施加的力下通过纤维环的内壁能够提供足够的穿透能力; 以及位于椎间盘内部分用于在所选择的位置处添加或移除能量或材料的功能元件。 还公开了使用该装置的方法。
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公开(公告)号：US20080039909A1
公开(公告)日：2008-02-14
申请号：US11872517
申请日：2007-10-15
申请人： Hugh Sharkey , John Ashley , Joel Saal , Jeffrey Saal , Le Trong Le
发明人： Hugh Sharkey , John Ashley , Joel Saal , Jeffrey Saal , Le Trong Le
CPC分类号： A61B17/1671 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/320016 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/08 , A61B18/082 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0133 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09 , A61N1/06 , A61N1/40 , A61N1/403
摘要： A device is described that may be positioned at a location in an intervertebral disc for diagnosis or treatment of the disc. Treatment may include, for example, applying energy or removing material, and may decrease intradiscal pressure. Radiofrequency energy may be applied. A percutaneous method of repairing a fissure in the annulus pulposus comprises placing an energy source adjacent to the fissure and providing sufficient energy to the fissure to raise the temperature to at least about 45-70° C. and for a sufficient time to cause the collagen to weld. An intervertebral fissure also can be treated by placing a catheter with a lumen adjacent to the fissure and injecting sealant into the fissure via the catheter, thereby sealing the fissure. An intervertebral fissure additionally can be treated by providing a catheter having a distal end, a proximal end, a longitudinal axis, and an intradiscal section at the catheter's distal end on which there is at least one functional element. The next step is applying a force longitudinally to the proximal of the catheter which is sufficient to advance the intradiscal section through the nucleus pulposus and around an inner wall of an annulus fibrosus, but which force is insufficient to puncture the annulus fibrosus. Next the functional element is positioned at a selected location of the disc by advancing or retracting the catheter and optionally twisting the proximal end of the catheter. Then the functional unit treats the annular fissure. Optionally, there is an additional step of adding a substance to seal the fissure. An externally guidable intervertebral disc apparatus also is disclosed.
摘要翻译： 描述了可以定位在椎间盘中的位置以用于椎间盘的诊断或治疗的装置。 治疗可以包括例如施加能量或去除材料，并且可以降低椎间盘内的压力。 可以应用射频能量。 修复环带中裂缝的经皮方法包括将能量源放置在裂缝附近并为裂缝提供足够的能量以将温度升高至至少约45-70℃，并持续足够的时间引起胶原 焊接。 也可以通过将具有腔的导管放置在裂缝附近并通过导管将密封剂注入到裂缝中，从而密封裂缝来治疗椎间裂。 另外可以通过在导管的远端提供具有远端，近端，纵向轴线和椎间盘内节段的导管来治疗椎间裂缝，在该导管的至少一个功能元件上。 下一步是向导管的近端施加一个力，这足以使椎间盘内部分通过髓核并绕纤维环的内壁延伸，但是哪个力不足以刺穿纤维环。 接下来，功能元件通过前进或缩回导管并且可选地扭转导管的近端来定位在盘的选定位置。 然后功能单元处理环形裂缝。 任选地，存在添加物质以密封裂缝的附加步骤。 还公开了一种外部引导性椎间盘装置。
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公开(公告)号：US07282061B2
公开(公告)日：2007-10-16
申请号：US10712007
申请日：2003-11-14
申请人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
发明人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
IPC分类号： A61F7/00
CPC分类号： A61B17/1671 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/320016 , A61B17/320068 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/08 , A61B18/082 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0133 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09 , A61N1/06 , A61N1/40 , A61N1/403
摘要： A device is described that may be positioned at a location in an intervertebral disc for diagnosis or treatment of the disc. Treatment may include, for example, applying energy or removing material, and may decrease intradiscal pressure. Radiofrequency energy may be applied. A percutaneous method of repairing a fissure in the annulus pulposus comprises placing an energy source adjacent to the fissure and providing sufficient energy to the fissure to raise the temperature to at least about 45-70° C. and for a sufficient time to cause the collagen to weld. An intervertebral fissure also can be treated by placing a catheter with a lumen adjacent to the fissure and injecting sealant into the fissure via the catheter, thereby sealing the fissure. An intervertebral fissure additionally can be treated by providing a catheter having a distal end, a proximal end, a longitudinal axis, and an intradiscal section at the catheter's distal end on which there is at least one functional element. The next step is applying a force longitudinally to the proximal of the catheter which is sufficient to advance the intradiscal section through the nucleus pulposus and around an inner wall of an annulus fibrosus, but which force is insufficient to puncture the annulus fibrosus. Next the functional element is positioned at a selected location of the disc by advancing or retracting the catheter and optionally twisting the proximal end of the catheter. Then the functional unit treats the annular fissure. Optionally, there is an additional step of adding a substance to seal the fissure. An externally guidable intervertebral disc apparatus also is disclosed.
摘要翻译： 描述了可以定位在椎间盘中的位置以用于椎间盘的诊断或治疗的装置。 治疗可以包括例如施加能量或去除材料，并且可以降低椎间盘内的压力。 可以应用射频能量。 修复环带中裂缝的经皮方法包括将能量源放置在裂缝附近并为裂缝提供足够的能量以将温度升高至至少约45-70℃，并且足够的时间使胶原蛋白 焊接。 也可以通过将具有腔的导管放置在裂缝附近并通过导管将密封剂注入到裂缝中，从而密封裂缝来治疗椎间裂。 另外可以通过在导管的远端提供具有远端，近端，纵向轴线和椎间盘内节段的导管来治疗椎间裂缝，在该导管的至少一个功能元件上。 下一步是向导管的近端施加一个力，这足以使椎间盘内部分通过髓核并绕纤维环的内壁延伸，但是哪个力不足以刺穿纤维环。 接下来，功能元件通过前进或缩回导管并且可选地扭转导管的近端来定位在盘的选定位置。 然后功能单元处理环形裂缝。 任选地，存在添加物质以密封裂缝的附加步骤。 还公开了一种外部引导性椎间盘装置。
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公开(公告)号：US08128619B2
公开(公告)日：2012-03-06
申请号：US11929644
申请日：2007-10-30
申请人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
发明人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
IPC分类号： A61B18/14
CPC分类号： A61B17/1671 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/320016 , A61B17/320068 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/08 , A61B18/082 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0133 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09 , A61N1/06 , A61N1/40 , A61N1/403
摘要： A method of treating an intervertebral disc includes inserting an introducer into an intervertebral disc, inserting a catheter through the introducer and into the intervertebral disc, advancing a distal region of the catheter through a nucleus pulposus of the intervertebral disc to an annular wall of an annulus fibrosus, delivering energy to material of the intervertebral disc using an electrode disposed at the distal region of the catheter, and removing the material with the delivered energy, wherein removing material with the delivered energy reduces pressure in the intervertebral disc.
摘要翻译： 治疗椎间盘的方法包括将导引器插入椎间盘，将导管穿过导引器插入椎间盘中，将导管的远侧区域推进通过椎间盘的髓核到环形的环形壁 纤维，使用设置在导管的远端区域的电极向椎间盘的材料输送能量，并且用所输送的能量去除材料，其中用所输送的能量去除材料减少了椎间盘中的压力。
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公开(公告)号：US06547810B1
公开(公告)日：2003-04-15
申请号：US09707627
申请日：2000-11-06
申请人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
发明人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
IPC分类号： A61F700
CPC分类号： A61B17/1671 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/320016 , A61B17/320068 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/08 , A61B18/082 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0133 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09 , A61N1/06 , A61N1/40 , A61N1/403
摘要： A percutaneous method of repairing a fissure in the annulus pulposus comprises placing an energy source adjacent to the fissure and providing sufficient energy to the fissure to raise the temperature to at least about 45-70° C. and for a sufficient time to cause the collagen to weld. An intervertebral fissure also can be treated by placing a catheter with a lumen adjacent to the fissure and injecting sealant into the fissure via the catheter, thereby sealing the fissure. An intervertebral fissure additionally can be treated by providing a catheter having a distal end, a proximal end, a longitudinal axis, and an intradiscal section at the catheter's distal end on which there is at least one functional element. The next step is applying a force longitudinally to the proximal of the catheter which is sufficient to advance the intradiscal section through the nucleus pulposus and around an inner wall of an annulus fibrosus, but which force is insufficient to puncture the annulus fibrosus. Next the functional element is positioned at a selected location of the disc by advancing or retracting the catheter and optionally twisting the proximal end of the catheter. Then the functional unit treats the annular fissure. Optionally, there is an additional step of adding a substance to seal the fissure. An externally guidable intervertebral disc apparatus also is disclosed.
摘要翻译： 修复环带中裂缝的经皮方法包括将能量源放置在裂缝附近并为裂缝提供足够的能量以将温度升高至至少约45-70℃，并且足够的时间使胶原蛋白 焊接。 也可以通过将具有腔的导管放置在裂缝附近并通过导管将密封剂注入到裂缝中，从而密封裂缝来治疗椎间裂。 另外可以通过在导管的远端提供具有远端，近端，纵向轴线和椎间盘内节段的导管来治疗椎间裂缝，在该导管的至少一个功能元件上。 下一步是向导管的近端施加一个力，这足以使椎间盘内部分通过髓核并绕纤维环的内壁延伸，但是哪个力不足以刺穿纤维环。 接下来，功能元件通过前进或缩回导管并且可选地扭转导管的近端来定位在盘的选定位置。 然后功能单元处理环形裂缝。 任选地，存在添加物质以密封裂缝的附加步骤。 还公开了一种外部引导性椎间盘装置。
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6.发明授权Method for delivering energy adjacent the inner wall of an intervertebral disc 有权用于在椎间盘的内壁附近递送能量的方法公开(公告)号：US06290715B1
公开(公告)日：2001-09-18
申请号：US09236816
申请日：1999-01-25
申请人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
发明人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
IPC分类号： A61F700
CPC分类号： A61B17/1671 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/320016 , A61B17/320068 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/08 , A61B18/082 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0133 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09 , A61N1/06 , A61N1/40 , A61N1/403
摘要： A percutaneous method of repairing a fissure in the annulus pulposus comprises placing an energy source adjacent to the fissure and providing sufficient energy to the fissure to raise the temperature to at least about 45-70° C. and for a sufficient time to cause the collagen to weld. An intervertebral fissure also can be treated by placing a catheter with a lumen adjacent to the fissure and injecting sealant into the fissure via the catheter, thereby sealing the fissure. An intervertebral fissure additionally can be treated by providing a catheter having a distal end, a proximal end, a longitudinal axis, and an intradiscal section at the catheter's distal end on which there is at least one functional element. The next step is applying a force longitudinally to the proximal of the catheter which is sufficient to advance the intradiscal section through the nucleus pulposus and around an inner wall of an annulus fibrosus, but which force is insufficient to puncture the annulus fibrosus. Next the functional element is positioned at a selected location of the disc by advancing or retracting the catheter and optionally twisting the proximal end of the catheter. Then the functional unit treats the annular fissure. Optionally, there is an additional step of adding a substance to seal the fissure. An externally guidable intervertebral disc apparatus also is disclosed.
摘要翻译： 修复环带中裂缝的经皮方法包括将能量源放置在裂缝附近并为裂缝提供足够的能量以将温度升高至至少约45-70℃，并且足够的时间使胶原蛋白 焊接。 也可以通过将具有腔的导管放置在裂缝附近并通过导管将密封剂注入到裂缝中，从而密封裂缝来治疗椎间裂。 另外可以通过在导管的远端提供具有远端，近端，纵向轴线和椎间盘内节段的导管来治疗椎间裂缝，在该导管的至少一个功能元件上。 下一步是向导管的近端施加一个力，这足以使椎间盘内部分通过髓核并绕纤维环的内壁延伸，但是哪个力不足以刺穿纤维环。 接下来，功能元件通过前进或缩回导管并且可选地扭转导管的近端来定位在盘的选定位置。 然后功能单元处理环形裂缝。 任选地，存在添加物质以密封裂缝的附加步骤。 还公开了一种外部引导性椎间盘装置。
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7.发明授权
公开(公告)号：US6099514A
公开(公告)日：2000-08-08
申请号：US162704
申请日：1998-09-29
申请人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
发明人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
IPC分类号： A61B17/00 , A61B17/16 , A61B17/22 , A61B17/28 , A61B17/32 , A61B17/34 , A61B17/88 , A61B18/00 , A61B18/04 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/24 , A61B19/00 , A61F2/30 , A61F2/44 , A61F7/02 , A61M1/00 , A61M25/00 , A61M25/01 , A61M25/09 , A61N1/06 , A61N1/40 , A61M5/00
CPC分类号： A61B17/1671 , A61B17/320016 , A61B17/320068 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/082 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61M25/0133 , A61N1/06 , A61N1/40 , A61N1/403 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/24 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61B34/20 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09
摘要： An externally guidable intervertebral disc apparatus manipulates disc tissue present at a selected location of an intervertebral disc, comprising a catheter having a distal end, a proximal end, and a longitudinal axis, the catheter having an intradiscal section at the distal end of the catheter, the intradiscal section being extendible into the disc, having sufficient rigidity to be advanceable through the nucleus pulposus of the disc under a force applied longitudinally to the proximal end, having sufficient flexibility in a direction of the disc plane to be compliant with the inner wall, having insufficient penetration ability to be advanceable through the inner wall of the annulus fibrosus under the applied force; and a functional element located in the intradiscal section for adding or removing energy or a material at the selected location of the disc. Methods of using the apparatus are also disclosed.
摘要翻译： 外部可导向的椎间盘装置操作存在于椎间盘的选定位置处的椎间盘组织，其包括具有远端，近端和纵向轴线的导管，所述导管在导管的远端处具有椎间盘内部分， 椎间盘内部分可延伸到椎间盘中，具有足够的刚性，以在纵向施加到近端的力的作用下通过盘的髓核推进，在盘平面的方向上具有足够的柔性以与内壁相一致， 在施加的力下通过纤维环的内壁能够提供足够的穿透能力; 以及位于椎间盘内部分用于在所选择的位置处添加或移除能量或材料的功能元件。 还公开了使用该装置的方法。
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公开(公告)号：US08187312B2
公开(公告)日：2012-05-29
申请号：US11872470
申请日：2007-10-15
申请人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
发明人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
CPC分类号： A61B17/1671 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/320016 , A61B17/320068 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/08 , A61B18/082 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0133 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09 , A61N1/06 , A61N1/40 , A61N1/403
摘要： A device is described that may be positioned at a location in an intervertebral disc for diagnosis or treatment of the disc. Treatment may include, for example, applying energy or removing material, and may decrease intradiscal pressure. Radiofrequency energy may be applied. A percutaneous method of repairing a fissure in the annulus pulposus comprises placing an energy source adjacent to the fissure and providing sufficient energy to the fissure to raise the temperature to at least about 45-70° C. and for a sufficient time to cause the collagen to weld. An intervertebral fissure also can be treated by placing a catheter with a lumen adjacent to the fissure and injecting sealant into the fissure via the catheter, thereby sealing the fissure. An intervertebral fissure additionally can be treated by providing a catheter having a distal end, a proximal end, a longitudinal axis, and an intradiscal section at the catheter's distal end on which there is at least one functional element. The next step is applying a force longitudinally to the proximal of the catheter which is sufficient to advance the intradiscal section through the nucleus pulposus and around an inner wall of an annulus fibrosus, but which force is insufficient to puncture the annulus fibrosus. Next the functional element is positioned at a selected location of the disc by advancing or retracting the catheter and optionally twisting the proximal end of the catheter. Then the functional unit treats the annular fissure. Optionally, there is an additional step of adding a substance to seal the fissure. An externally guidable intervertebral disc apparatus also is disclosed.
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公开(公告)号：US07400930B2
公开(公告)日：2008-07-15
申请号：US10712006
申请日：2003-11-14
申请人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
发明人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
IPC分类号： A61N1/06
CPC分类号： A61B17/1671 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/320016 , A61B17/320068 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/08 , A61B18/082 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0133 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09 , A61N1/06 , A61N1/40 , A61N1/403
摘要： A method of manipulating a disc tissue of an intervertebral disc is described, the disc has a nucleus pulposus, an annulus fibrosus, and an inner wall of the annulus fibrosus. The method includes providing a catheter having a radiofrequency electrode at a distal region of the catheter and a proximal region for externally guiding the distal region of the catheter within an intervertebral disc. The method also includes positioning the electrode at the inner wall of the annulus fibrosus by applying a sufficient force to advance the catheter through the nucleus pulposus to the inner wall of the annulus fibrosus. The force is insufficient to puncture the annulus fibrosus. The method further includes delivering energy to the disc tissue using the electrode.
摘要翻译： 描述了一种操纵椎间盘的椎间盘组织的方法，该椎间盘具有髓核，纤维环和纤维环的内壁。 该方法包括提供在导管的远端区域处具有射频电极的导管和用于在椎间盘内外部引导导管的远侧区域的近端区域。 该方法还包括通过施加足够的力将导管穿过髓核推进到纤维环的内壁来将电极定位在纤维环的内壁处。 力不足以刺穿纤维环。 该方法还包括使用电极将能量递送到盘组织。
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10.发明授权公开(公告)号：US06997941B2
公开(公告)日：2006-02-14
申请号：US10388609
申请日：2003-03-17
申请人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
发明人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
IPC分类号： A61F7/00
CPC分类号： A61B17/1671 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/320016 , A61B17/320068 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/08 , A61B18/082 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0133 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09 , A61N1/06 , A61N1/40 , A61N1/403
摘要： A device is described that may be positioned at a location in an intervertebral disc for diagnosis or treatment of the disc. Treatment may include, for example, applying energy or removing material, and may decrease intradiscal pressure. Radiofrequency energy may be applied. A percutaneous method of repairing a fissure in the annulus pulposus comprises placing an energy source adjacent to the fissure and providing sufficient energy to the fissure to raise the temperature to at least about 45-70° C. and for a sufficient time to cause the collagen to weld. An intervertebral fissure also can be treated by placing a catheter with a lumen adjacent to the fissure and injecting sealant into the fissure via the catheter, thereby sealing the fissure. An intervertebral fissure additionally can be treated by providing a catheter having a distal end, a proximal end, a longitudinal axis, and an intradiscal section at the catheter's distal end on which there is at least one functional element. The next step is applying a force longitudinally to the proximal of the catheter which is sufficient to advance the intradiscal section through the nucleus pulposus and around an inner wall of an annulus fibrosus, but which force is insufficient to puncture the annulus fibrosus. Next the functional element is positioned at a selected location of the disc by advancing or retracting the catheter and optionally twisting the proximal end of the catheter. Then the functional unit treats the annular fissure. Optionally, there is an additional step of adding a substance to seal the fissure. An externally guidable intervertebral disc apparatus also is disclosed.
摘要翻译： 描述了可以定位在椎间盘中的位置以用于椎间盘的诊断或治疗的装置。 治疗可以包括例如施加能量或去除材料，并且可以降低椎间盘内的压力。 可以应用射频能量。 修复环带中裂缝的经皮方法包括将能量源放置在裂缝附近并为裂缝提供足够的能量以将温度升高至至少约45-70℃，并且足够的时间使胶原蛋白 焊接。 也可以通过将具有腔的导管放置在裂缝附近并通过导管将密封剂注入到裂缝中，从而密封裂缝来治疗椎间裂。 另外可以通过在导管的远端提供具有远端，近端，纵向轴线和椎间盘内节段的导管来治疗椎间裂缝，在该导管的至少一个功能元件上。 下一步是向导管的近端施加一个力，这足以使椎间盘内部分通过髓核并绕纤维环的内壁延伸，但是哪个力不足以刺穿纤维环。 接下来，功能元件通过前进或缩回导管并且可选地扭转导管的近端来定位在盘的选定位置。 然后功能单元处理环形裂缝。 任选地，存在添加物质以密封裂缝的附加步骤。 还公开了一种外部引导性椎间盘装置。
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