公开(公告)号：US4480036A

公开(公告)日：1984-10-30

申请号：US176527

申请日：1980-08-08

申请人： Hugh W. Morgan ,  Roy M. Daniel ,  Donald A. Cowan ,  Christopher W. Hickey

发明人： Hugh W. Morgan ,  Roy M. Daniel ,  Donald A. Cowan ,  Christopher W. Hickey

IPC分类号： C12N1/00 ,  C12N1/20 ,  C12N9/52 ,  C12N11/02 ,  C12N11/06 ,  C12N11/10 ,  C12N11/12 ,  C12N11/14

CPC分类号： C12R1/01 ,  C12N11/10 ,  C12N11/14 ,  C12N9/52 ,  Y10S435/815 ,  Y10S435/822

摘要： The invention relates to an extremely thermophilic bacterium, Thermus T-351, and a thermophilic protease, Caldolysin, derived therefrom. The bacterium cells are Gram negative, non-sporulating rods. Its natural environment is a hot pool at 79.degree..+-.4.degree. C. The protease is stable at temperatures up to 75.degree. C. at a pH range of 4 to 12. It is most active at temperatures of 65.degree. C. to 85.degree. C. but retains at least some activity at lower temperatures.