公开(公告)号：US20240109063A1

公开(公告)日：2024-04-04

申请号：US18374062

申请日：2023-09-28

Applicant: ILLUMINA, INC.

Inventor： Dustin BLAIR ,  Patrick WEN ,  John EARNEY ,  Anmiv PRABHU ,  Rachel ABASKHARON ,  Gregory HOLST ,  Chia-Hsi LIU ,  Ravi THAKUR ,  Dakota WATSON ,  Kevin BARTIG ,  Daeyong SIM

IPC: B01L3/00 ,  C12Q1/6874 ,  G01N21/64

CPC classification number: B01L3/502715 ,  C12Q1/6874 ,  G01N21/6428 ,  B01L2200/148 ,  B01L2300/0654 ,  G01N2021/6439 ,  G01N2201/12723

Abstract: An apparatus includes a flow cell, an imaging assembly, and a processor. The flow cell includes a channel and a plurality of reaction sites. The imaging assembly is operable to receive light emitted from the reaction sites in response to an excitation light. The processor is configured to drive relative movement between at least a portion of the imaging assembly and the flow cell along a continuous range of motion to thereby enable the imaging assembly to capture images along the length of the channel. The processor is also configured to activate the imaging assembly to capture one or more calibration images of one or more calibration regions of the channel, during a first portion of the continuous range of motion. The processor is also configured to activate the imaging assembly to capture images of the reaction sites during a second portion of the continuous range of motion.

公开(公告)号：US20160160276A1

公开(公告)日：2016-06-09

申请号：US14906536

申请日：2014-08-28

Applicant: ILLUMINA, INC.

Inventor： John EARNEY ,  Dakota WATSON ,  Joseph PINTO

IPC: C12Q1/68 ,  G01N21/05 ,  H04N17/00 ,  G01N21/64

CPC classification number: B01L3/502715 ,  B01L3/502723 ,  B01L2300/0816 ,  B01L2300/0819 ,  B01L2300/0883 ,  B01L2300/14 ,  C12Q1/6874 ,  G01N21/05 ,  G01N21/6428 ,  G01N21/645 ,  G01N2021/058 ,  G01N2021/6439 ,  G01N2021/6482 ,  H04N17/002

Abstract: Provided is an inspection apparatus including: (a) a translucent or transparent plate having a bottom surface, at least a portion of the bottom surface having an opaque material printed thereon in a pattern having at least one transparent or translucent portion; and (b) a chamber disposed below the bottom surface, whereby light emitted from the chamber or through the chamber can pass through the at least one transparent or translucent portion.

Abstract translation: 提供了一种检查装置，包括：（a）具有底表面的半透明或透明板，底表面的至少一部分具有印刷在其上的不透明材料，图案具有至少一个透明或半透明部分; 和（b）设置在所述底表面下方的室，由此从所述室或通过所述室发射的光可穿过所述至少一个透明或半透明部分。