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    TREATMENT DEVICES AND METHODS
    2.
    发明申请
    TREATMENT DEVICES AND METHODS 审中-公开

    公开(公告)号：US20200030026A1

    公开(公告)日：2020-01-30

    申请号：US16592020

    申请日：2019-10-03

    申请人： Innoblative Designs, Inc.

    发明人： Robert F. Rioux ,  Michelle Hasse ,  Tyler Wanke

    IPC分类号： A61B18/14

    摘要： The present invention is directed to a medical device for providing treatment to diseased tissue and cells. The medical device is configured to ablate a target tissue surface, optionally within a resection cavity, and further deliver a therapeutic that targets diseased (e.g., cancer) cells via a marker whose expression is upregulated by the ablation. The ablation directly kills diseased cells associated with the tissue surface. While some diseased cells evade direct ablation, those cells nevertheless upregulate certain cell surface markers in response to the ablation, even while other, healthy or normal cells do not upregulate expression of the marker in response to the ablation. Devices and methods disclosed herein are used to deliver a therapeutic that uses the upregulated cell surface marker to cause the death of those diseased cells.

    CAVITARY TISSUE ABLATION
    4.
    发明申请
    CAVITARY TISSUE ABLATION 有权

    公开(公告)号：US20220125506A1

    公开(公告)日：2022-04-28

    申请号：US17569191

    申请日：2022-01-05

    申请人： Innoblative Designs, Inc.

    发明人： Zachary Rzeszutek ,  Tyler Wanke ,  Robert F. Rioux ,  Alyssa Bailey ,  Thomas Kurth

    IPC分类号： A61B18/14

    摘要： The invention relates to a tissue ablation system including an ablation device having a deployable applicator, preferably, with a non-spherical head configured to be delivered to a tissue cavity and ablate marginal tissue surrounding the tissue cavity. The deployable applicator head is configured to be delivered to a tissue cavity while in a collapsed configuration and ablate marginal tissue surrounding the tissue cavity while in an expanded configuration.

    Treatment devices and methods
    5.
    发明授权
    Treatment devices and methods 有权

    公开(公告)号：US10470818B2

    公开(公告)日：2019-11-12

    申请号：US16122111

    申请日：2018-09-05

    申请人： Innoblative Designs, Inc.

    发明人： Robert F. Rioux ,  Michelle Hasse ,  Tyler Wanke

    IPC分类号： A61B18/14 ,  A61B18/00 ,  A61B5/042 ,  A61B5/01 ,  A61B5/053

    摘要： The present invention is directed to a medical device for providing treatment to diseased tissue and cells. The medical device is configured to ablate a target tissue surface, optionally within a resection cavity, and further deliver a therapeutic that targets diseased (e.g., cancer) cells via a marker whose expression is upregulated by the ablation. The ablation directly kills diseased cells associated with the tissue surface. While some diseased cells evade direct ablation, those cells nevertheless upregulate certain cell surface markers in response to the ablation, even while other, healthy or normal cells do not upregulate expression of the marker in response to the ablation. Devices and methods disclosed herein are used to deliver a therapeutic that uses the upregulated cell surface marker to cause the death of those diseased cells.

    MINIMALLY INVASIVE ARTICULATING ASSEMBLY HAVING ABLATION CAPABILITIES
    10.
    发明公开
    MINIMALLY INVASIVE ARTICULATING ASSEMBLY HAVING ABLATION CAPABILITIES 审中-公开

    公开(公告)号：US20240156522A1

    公开(公告)日：2024-05-16

    申请号：US18380607

    申请日：2023-10-16

    申请人： Innoblative Designs, Inc.

    发明人： Robert F. Rioux ,  Alyssa Bailey ,  Tyler Wanke ,  Ryan M. Bean

    IPC分类号： A61B18/14 ,  A61B18/12 ,  A61B90/00

    CPC分类号： A61B18/1492 ,  A61B18/1206 ,  A61B90/37 ,  A61B2018/00255 ,  A61B2090/3762 ,  A61B2090/378

    摘要： The present invention is a minimally invasive articulating configured to be advanced through tortuous anatomy, particularly within a lung, and subsequently deliver at least two separately deployable ablation devices to a target site located at a bifurcated section of the lung (i.e., at a bronchial airway bifurcation). The pair of ablation devices are separately steerable towards respective first and second pathways extending from the bifurcation, such that each of the ablation devices can be positioned on either side of a target tissue proximate the bifurcation. The first and second ablation devices include expandable distal tips configured to transition to a deployed configuration, in which each expands in diameter and is configured to apply a degree of compression and/or RF energy emission to target lung tissue (i.e., diseased tissue, such as cancer or emphysema-related damaged tissue) for subsequent ablation thereof.