公开(公告)号：US20240050686A1

公开(公告)日：2024-02-15

申请号：US18225483

申请日：2023-07-24

Applicant: INOSYSTEMS

Inventor： Thierry BOULANGER ,  Frederic MARCHAL ,  Mary SCHMITT

IPC: A61M16/12 ,  G05D7/06 ,  A61M16/20

CPC classification number: A61M16/12 ,  G05D7/0676 ,  A61M16/203 ,  A61M2016/0033

Abstract: An installation for supplying gas to a patient, comprises an NO delivery device, an NO injection line with a valve device, a backup line that connects to the injection line and comprises a backup solenoid valve and a flow rate control device, and control means; and a medical ventilator that supplies a respiratory gas to a patient circuit to which the NO delivery device is connected. A flow rate sensor supplies the control means with a measurement signal of the gas flow rate in the patient circuit. In the event of interruption of reception of the measurement signal, the backup solenoid valve switches to an open position, the valve device switches to a closed position and the flow rate control device supplies the NO/N2 mixture at a pre-regulated backup flow rate, determined on the basis of the measurement signal supplied by the flow rate sensor, before said interruption.

公开(公告)号：US20230235852A1

公开(公告)日：2023-07-27

申请号：US18093212

申请日：2023-01-04

Applicant: INOSYSTEMS

Inventor： Thierry BOULANGER ,  Frederic MARCHAL

IPC: F17C1/14 ,  A61M16/10

CPC classification number: F17C1/14 ,  A61M16/10 ,  F17C2201/058 ,  F17C2205/0323 ,  F17C2221/03 ,  F17C2223/035 ,  F17C2201/0123 ,  F17C2203/0646 ,  F17C2270/025 ,  F17C2223/0123 ,  A61M2202/0275 ,  A61M2202/0208 ,  A61M2202/0266

Abstract: Disclosed is a cartridge for storing pressurized gas, including a main body with an internal volume for storing a gaseous mixture NO/N2, and a distribution valve for controlling the output of the gas. The internal volume of the main body is less than 1000 ml. The concentration of NO in the gaseous mixture NO/N2 is between 15000 and 25000 ppmv. The gas pressure in the internal volume is below 15 bar, measured at 23° C. Installation for delivering gas to a patient, including such a gas cartridge, a NO supply device fed by the gas cartridge, and a medical ventilator feeding a patient circuit which has an inhalation branch fed by the NO supply device. Use for treating patients suffering from pulmonary hypertension or hypoxia.

公开(公告)号：US20230211113A1

公开(公告)日：2023-07-06

申请号：US18093094

申请日：2023-01-04

Applicant: INOSYSTEMS

Inventor： Thierry BOULANGER ,  Frédéric MARCHAL ,  Mary SCHMITT

IPC: A61M16/12 ,  A61M16/00

CPC classification number: A61M16/12 ,  A61M16/024 ,  A61M16/16

Abstract: Disclosed is an NO delivery device for supplying an NO-containing gas, including an NO injection line, a flow rate measurement device and a valve device. The valve device is normally closed. An emergency line connected to the injection line includes an emergency solenoid valve, which is normally open, and a flow rate control device. An operating unit operates these elements. In the event of malfunction of the operating unit, the emergency solenoid valve passes to an open position, whilst the valve device passes to a closed position. The flow rate control device supplies the gas at a pre-fixed emergency flow rate of gas, determined on the basis of the gas flow rate measurements supplied by the flow rate measurement device during the normal functioning of the device prior to the malfunction. Gas supply installation including such an NO delivery device and a medical ventilator.

公开(公告)号：US20240366907A1

公开(公告)日：2024-11-07

申请号：US18638741

申请日：2024-04-18

Applicant: INOSYSTEMS

Inventor： Frederic MARCHAL ,  Thierry BOULANGER ,  Yann BLANDIN ,  Mary SCHMITT

IPC: A61M16/20 ,  A61M16/00 ,  A61M16/12

Abstract: The invention relates to an apparatus for supplying NO (1), such as an NO/N2 gaseous mixture, comprising a main gas circuit (40; 40.1, 40.2) with flow rate control means (42, 43) comprising at least one main solenoid valve (42) operated by the operating means (50) in order to control the flow rate of NO/N2 mixture passing through said at least one main solenoid valve (42). The main solenoid valve (42) is a proportional solenoid valve having degrees of opening of between 0 and 100%, and is configured to function in at least two given operating ranges corresponding to different degrees of opening of the main solenoid valve (42). The operating means (50) are configured to control the main solenoid valve (42) in pulsed mode in one of the operating ranges so as to deliver successive gas pulses (IG) and in proportional mode in another operating range.

公开(公告)号：US20240316298A1

公开(公告)日：2024-09-26

申请号：US18610366

申请日：2024-03-20

Applicant: INOSYSTEMS

Inventor： Thierry BOULANGER ,  Frederic MARCHAL ,  Akshar PATEL

IPC: A61M16/00

CPC classification number: A61M16/0003 ,  A61M2205/3327 ,  A61M2205/3337

Abstract: The invention relates to a calibration device (2) for calibrating the measuring means (120-122) of an NO delivery apparatus (1), comprising a gas intake line (22) comprising, arranged in series, a valve, preferably manual (23) and actuatable by a user, for controlling the circulation of gas in the gas intake line (22); a precision regulator (24) configured to deliver a predefined fixed pressure in the gas intake line (22); a calibrated orifice device (25), and a venturi device (26). The measuring means of the NO delivery apparatus comprise an NO sensor, an NO2 sensor and an O2 sensor.

公开(公告)号：US20250121153A1

公开(公告)日：2025-04-17

申请号：US18911826

申请日：2024-10-10

Applicant: INOSYSTEMS

Inventor： Thierry BOULANGER ,  Frederic MARCHAL ,  Mary SCHMITT

IPC: A61M16/10 ,  A61M16/00 ,  A61M16/08

Abstract: The invention relates to an NO delivery apparatus (1) having a main gas circuit for conveying an NO-containing gas, in particular an NO/N2 mixture, an analysis line (110) comprising NO/NO2 measuring device(s) (120, 121) configured to perform NO and/or NO2 concentration measurements within said analysis line (110), and a controller (15) connected to said NO/NO2 measuring device (120, 121) and configured to process the NO and/or NO2 concentration measurements performed by said NO/NO2 measuring device (120, 121). In addition, the analysis line (110) comprises piezoelectric suction device (141) controlled by the controller (15).

公开(公告)号：US20250121146A1

公开(公告)日：2025-04-17

申请号：US18912945

申请日：2024-10-11

Applicant: INOSYSTEMS

Inventor： Yann BLANDIN ,  Frederic MARCHAL ,  Mary SCHMITT ,  Thierry BOULANGER

IPC: A61M16/00 ,  A61M16/10 ,  A61M16/20

Abstract: The invention relates to an apparatus (1) for supplying an NO-containing gas, comprising at least one internal passage (6) with valve means (7) for conveying a flow of NO-containing gas; a graphic display (4), and control means (8) with a microprocessor (9) cooperating at least with the valve means (7) in order to control the supply of gas. Storage means (70) are provided for storing a pre-set non-zero dose of NO (NOmém). The control means (8) control a default display (at 71), on the graphic display (4), of the pre-set starting dose of NO (NOmém) that has been stored.