公开(公告)号：US11904098B2

公开(公告)日：2024-02-20

申请号：US15535878

申请日：2014-12-19

Applicant: INOSYSTEMS

Inventor： Magnus Westermark ,  Lars-Erik Nilsson

IPC: A61M16/12 ,  A61M16/00 ,  A61M16/08 ,  A61M16/10 ,  A61M16/16

CPC classification number: A61M16/12 ,  A61M16/0078 ,  A61M16/024 ,  A61M16/085 ,  A61M16/104 ,  A61M16/16 ,  A61M2016/003 ,  A61M2016/0039 ,  A61M2016/102 ,  A61M2016/1035 ,  A61M2202/0275 ,  A61M2205/16 ,  A61M2205/3334 ,  A61M2205/50 ,  A61M2205/505

Abstract: An additive gas delivery apparatus for delivery of additive gas to inspirational gas can be set to deliver the additive gas according to a dosing setting in normal therapy, and can be set to deliver according to a backup dosing setting in response disruption of signals representing data for controlling the delivery of additive gas according to the dosing setting in normal therapy. An additive gas delivery apparatus has an inlet for the additive gas and an integrated inlet for gas for oxygenating the patient that are connected to a backup line to mix the additive gas and gas for oxygenating the patient to a set concentration of additive gas in the gas mixture at an integrated backup outlet of the additive gas delivery apparatus.

公开(公告)号：US20240050686A1

公开(公告)日：2024-02-15

申请号：US18225483

申请日：2023-07-24

Applicant: INOSYSTEMS

Inventor： Thierry BOULANGER ,  Frederic MARCHAL ,  Mary SCHMITT

IPC: A61M16/12 ,  G05D7/06 ,  A61M16/20

CPC classification number: A61M16/12 ,  G05D7/0676 ,  A61M16/203 ,  A61M2016/0033

Abstract: An installation for supplying gas to a patient, comprises an NO delivery device, an NO injection line with a valve device, a backup line that connects to the injection line and comprises a backup solenoid valve and a flow rate control device, and control means; and a medical ventilator that supplies a respiratory gas to a patient circuit to which the NO delivery device is connected. A flow rate sensor supplies the control means with a measurement signal of the gas flow rate in the patient circuit. In the event of interruption of reception of the measurement signal, the backup solenoid valve switches to an open position, the valve device switches to a closed position and the flow rate control device supplies the NO/N2 mixture at a pre-regulated backup flow rate, determined on the basis of the measurement signal supplied by the flow rate sensor, before said interruption.

公开(公告)号：US20240366907A1

公开(公告)日：2024-11-07

申请号：US18638741

申请日：2024-04-18

Applicant: INOSYSTEMS

Inventor： Frederic MARCHAL ,  Thierry BOULANGER ,  Yann BLANDIN ,  Mary SCHMITT

IPC: A61M16/20 ,  A61M16/00 ,  A61M16/12

Abstract: The invention relates to an apparatus for supplying NO (1), such as an NO/N2 gaseous mixture, comprising a main gas circuit (40; 40.1, 40.2) with flow rate control means (42, 43) comprising at least one main solenoid valve (42) operated by the operating means (50) in order to control the flow rate of NO/N2 mixture passing through said at least one main solenoid valve (42). The main solenoid valve (42) is a proportional solenoid valve having degrees of opening of between 0 and 100%, and is configured to function in at least two given operating ranges corresponding to different degrees of opening of the main solenoid valve (42). The operating means (50) are configured to control the main solenoid valve (42) in pulsed mode in one of the operating ranges so as to deliver successive gas pulses (IG) and in proportional mode in another operating range.

公开(公告)号：US20240316298A1

公开(公告)日：2024-09-26

申请号：US18610366

申请日：2024-03-20

Applicant: INOSYSTEMS

Inventor： Thierry BOULANGER ,  Frederic MARCHAL ,  Akshar PATEL

IPC: A61M16/00

CPC classification number: A61M16/0003 ,  A61M2205/3327 ,  A61M2205/3337

Abstract: The invention relates to a calibration device (2) for calibrating the measuring means (120-122) of an NO delivery apparatus (1), comprising a gas intake line (22) comprising, arranged in series, a valve, preferably manual (23) and actuatable by a user, for controlling the circulation of gas in the gas intake line (22); a precision regulator (24) configured to deliver a predefined fixed pressure in the gas intake line (22); a calibrated orifice device (25), and a venturi device (26). The measuring means of the NO delivery apparatus comprise an NO sensor, an NO2 sensor and an O2 sensor.

公开(公告)号：US20230285710A1

公开(公告)日：2023-09-14

申请号：US18119204

申请日：2023-03-08

Applicant: INOSYSTEMS

Inventor： Frederic MARCHAL

IPC: A61M16/12 ,  A61M16/20

CPC classification number: A61M16/122 ,  A61M16/202 ,  A61M2205/502 ,  A61M2016/0033

Abstract: Disclosed is an NO supply device including a main gas circuit to convey an NO/N2 mixture to a main output orifice which is designed to supply the inspiratory branch of a medical ventilator; and a backup circuit including a backup NO circuit including a backup NO line which is supplied with NO/N2 mixture, and a backup O2 circuit includes a main O2 line which is connected fluidically to the backup NO line in order to form a common line in fluid communication with a secondary output which supplies an NO/N2/O2 mixture designed to supply a manual breathing bag.

公开(公告)号：US20250001108A1

公开(公告)日：2025-01-02

申请号：US18752962

申请日：2024-06-25

Applicant: INOSYSTEMS

Inventor： Yann BLANDIN ,  Mary SCHMITT ,  Frederic MARCHAL ,  Nathan PROUVEZ

IPC: A61M16/00 ,  A61M16/12

Abstract: The invention relates to an apparatus (1) for supplying an NO-containing gas, comprising an internal circuit (6) for conveying a flow of NO-containing gas, comprising valve means (7), control means (8) with a microprocessor (9), a tactile graphical display screen (4), and a gas analysis line (111) comprising at least one sensor (112). The control means (8) are configured to control, at a given time frequency, a temporary display, on the graphical display screen (4), of a first virtual selection key (81), the actuation of which by a user initiates a procedure of calibration of the sensor or sensors (112) of the gas analysis line (111).

公开(公告)号：US20240261530A1

公开(公告)日：2024-08-08

申请号：US18420922

申请日：2024-01-24

Applicant: INOSYSTEMS

Inventor： Nicolas TIRILLY ,  Christian KAHALE

IPC: A61M16/14

CPC classification number: A61M16/14 ,  A61M2202/0275 ,  A61M2209/082

Abstract: The invention relates to a medical apparatus (1) for supplying gas, such as gaseous NO, comprising a shell (2) and a device (10), arranged on said shell (2), for fixing the latter to an elongate support (S). The fixing device (10) comprises a clamp body (12) and a clamp element (13) movable by pivoting (XX) relative to each other, which are configured as a first jaw (15) and a second jaw (16) forming a clamp. A rotary manipulation member (11), which can be actuated in rotation, allows the jaws (15, 16) to be moved towards or away from each other. It comprises a head (11.1) intended to be grasped manually by the user, and an actuation rod (11.2) with a threaded portion (11.4) cooperating with an internally threaded actuation part in order to move the jaws (15, 16) towards or away from each other. A torque-limiting system (20) is arranged in the head (11.1) of the rotary manipulation member (11). It comprises a stack of spring washers (21) cooperating with a pressure washer (24).

公开(公告)号：US20230235852A1

公开(公告)日：2023-07-27

申请号：US18093212

申请日：2023-01-04

Applicant: INOSYSTEMS

Inventor： Thierry BOULANGER ,  Frederic MARCHAL

IPC: F17C1/14 ,  A61M16/10

CPC classification number: F17C1/14 ,  A61M16/10 ,  F17C2201/058 ,  F17C2205/0323 ,  F17C2221/03 ,  F17C2223/035 ,  F17C2201/0123 ,  F17C2203/0646 ,  F17C2270/025 ,  F17C2223/0123 ,  A61M2202/0275 ,  A61M2202/0208 ,  A61M2202/0266

Abstract: Disclosed is a cartridge for storing pressurized gas, including a main body with an internal volume for storing a gaseous mixture NO/N2, and a distribution valve for controlling the output of the gas. The internal volume of the main body is less than 1000 ml. The concentration of NO in the gaseous mixture NO/N2 is between 15000 and 25000 ppmv. The gas pressure in the internal volume is below 15 bar, measured at 23° C. Installation for delivering gas to a patient, including such a gas cartridge, a NO supply device fed by the gas cartridge, and a medical ventilator feeding a patient circuit which has an inhalation branch fed by the NO supply device. Use for treating patients suffering from pulmonary hypertension or hypoxia.

公开(公告)号：US20240277960A1

公开(公告)日：2024-08-22

申请号：US18428357

申请日：2024-01-31

Applicant: INOSYSTEMS

Inventor： Yann BLANDIN ,  Mary SCHMITT ,  Frederic MARCHAL

IPC: A61M16/00

CPC classification number: A61M16/024 ,  A61M16/0075 ,  A61M2202/0007 ,  A61M2202/0275 ,  A61M2205/3327 ,  A61M2205/3331 ,  A61M2205/505 ,  A61M2205/52

Abstract: The invention relates to a device (1) for supplying therapeutic gas, in particular NO/N2 mixtures, comprising an internal passage (2), valve means (5), control means (6) with microprocessor, and selection means (8), which can be actuated by a user and are configured to allow the user to start a supply of gas or stop a supply of gas. The selection means (8) supply the control means (6) with a command signal corresponding to the choice made by the user, in order to control, via the valve means (5), the flow of gas in the internal passage (2), i.e. to authorize or stop any flow of gas. The control means (6) count a total duration of actual supply of gas equal to the sum of all the time periods elapsing between a choice, made by the user, of starting a supply of gas and a choice, made by the user, of stopping a supply of gas. Installation for administering gas to a patient, which includes such a gas supply apparatus.

公开(公告)号：US12012140B2

公开(公告)日：2024-06-18

申请号：US17954763

申请日：2022-09-28

Applicant: INOSYSTEMS

Inventor： Frédéric Marchal ,  Nicolas Tirilly

IPC: B62B3/10 ,  B62B3/04 ,  B62B5/00 ,  B62B5/06

CPC classification number: B62B3/104 ,  B62B5/00 ,  B62B5/06 ,  B62B3/04 ,  B62B2202/022 ,  B62B2203/44 ,  B62B2301/044

Abstract: Disclosed is a mobile cart including a base for accommodating one or more gas cylinders, castors, a main column extending upwards from the base, a stowage cabinet arranged along the main column, an anchoring structure arranged at an upper end of the main column, a support post carried by the anchoring structure and equipped with fixing unit for a gas delivery apparatus, and a manual gripping handle allowing a user to manipulate the cart. Use of such a mobile cart to transport one or more cylinders of gas, in particular a NO/N2 mixture and/or oxygen, and a gas delivery apparatus.