公开(公告)号：US20190010413A1

公开(公告)日：2019-01-10

申请号：US16068258

申请日：2017-01-12

申请人： INOVENTEAM ,  UNIVERSITE CLAUDE BERNARD LYON 1 ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

发明人： Arthur MARAIS ,  Mahmoud OULD-METIDJI ,  Florian LEPOIVRE ,  Anatole COLLET ,  Matteo MARTINI ,  Fabien ROSSETTI ,  Olivier TILLEMENT ,  Antoine VANLAER ,  François GHILLEBAERT

IPC分类号： C10L1/00 ,  C10L1/30 ,  C10M171/00 ,  G01N21/64

摘要： The use, as markers of petroleum products, crude oils, biofuels or lubricants, of rare earth complexes or one of the constituents thereof chosen from rare earth ligands or salts, being capable of forming a rare earth complex after the addition of a developing solution. Preferably, the rare earth complex can be detected by time-resolved fluorescence. Also, a marking method and a method for detecting a rare earth complex as a marker of petroleum products, crude oils, biofuels or lubricants.

公开(公告)号：US20230173155A1

公开(公告)日：2023-06-08

申请号：US17997763

申请日：2021-04-30

申请人： MEXBRAIN ,  UNIVERSITE CLAUDE BERNARD LYON 1 ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - ,  INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) ,  INSTITUT GUSTAVE ROUSSY ,  VETAGRO-SUP INSTITUT D'ENSEIGNEMENT SUPÉRIEUR ET DE RECHERCHE

发明人： Marco NATUZZI ,  Thomas BRICHART ,  Fabien ROSSETTI ,  Matteo MARTINI ,  François LUX ,  Olivier TILLEMENT ,  Jean-Luc PERFETTINI ,  Vanessa LOUZIER ,  Jeanne-Marie BONNET-GARIN ,  Jean-Yves AYOUB

IPC分类号： A61M1/16

CPC分类号： A61M1/1621 ,  A61M1/1654

摘要： The present invention relates to the field of medical devices, more particularly the field of devices for extracting circulating molecules from the blood of a mammal, and their therapeutic uses, in particular in treating sepsis, cytokine release syndrome and/or any other form of systemic inflammatory response or cytokine shock, caused by bacterial, parasitic, fungal or viral infections, in particular caused by a viral infection, for example coronaviruses with human respiratory tract tropism.

公开(公告)号：US20200289623A1

公开(公告)日：2020-09-17

申请号：US16755866

申请日：2018-10-12

申请人： NH THERAGUIX ,  Universite Claude Bernard Lyon 1 ,  Centre National de La Recherche Scientifique - CNRS -

发明人： Olivier TILLEMENT ,  François LUX ,  Fabien ROSSETTI ,  Vu-Long TRAN ,  Clélia MATHIEU ,  Myleva DAHAN

IPC分类号： A61K38/31 ,  A61K31/704 ,  A61K47/69 ,  A61K49/00 ,  A61P35/00 ,  A61K49/12 ,  A61K49/18 ,  A61K9/14 ,  A61K33/243 ,  B82Y5/00

摘要： The present invention relates to the field of nanovectors for the delivery of active substances in the body, in particular for the treatment of tumours. In particular, the use of these nanovectors makes it possible to improve the pharmacokinetics of the active substances with a more selective delivery, for example in the tumour tissues.

公开(公告)号：US20230405154A1

公开(公告)日：2023-12-21

申请号：US18253586

申请日：2021-11-19

申请人： NH THERAGUIX ,  UNIVERSITE CLAUDE BERNARD LYON 1 ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -

发明人： Olivier TILLEMENT ,  François LUX ,  Fabien ROSSETTI ,  Paul ROCCHI ,  Tristan DOUSSINEAU

IPC分类号： A61K49/18 ,  A61K51/12

CPC分类号： A61K49/1881 ,  A61K51/1244 ,  B82Y5/00

摘要： The present disclosure relates to nanoparticles and the uses thereof in medicine, in particular for the treatment of tumours.

公开(公告)号：US20230263912A1

公开(公告)日：2023-08-24

申请号：US18007254

申请日：2021-07-29

申请人： MEXBRAIN ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS ,  UNIVERSITE CLAUDE BERNARD LYON 1

发明人： Olivier TILLEMENT ,  François LUX ,  Fabien ROSSETTI ,  Marco NATUZZI ,  Thomas BRICHART ,  Laurent DAVID ,  Paula NUNES DE OLIVEIRA ,  Alexandra MONTEBAULT

IPC分类号： A61K49/12 ,  C08B37/08

CPC分类号： A61K49/128 ,  C08B37/003

摘要： The invention relates to a statistical polysaccharide with a weight-average molecular weight of between 100 kDa and 1000 kDa of the following formula (I): in which: each Rc independently represents a group containing a chelating agent, each Z independently represents a binder which may be a single bond or a hydrocarbon chain containing between 1 and 12 carbon atoms, said chain able to be either linear or branched and being able to contain one or more unsaturations and being able to contain one or more heteroatoms, preferably chosen from nitrogen, oxygen, sulfur and atoms of the halogen family, x is between 0.005 and 0.7, preferably between 0.05 and 0.7, and preferentially between 0.2 and 0.6, y is between 0.01 and 0.7, preferably between 0.05 and 0.2, the ratio of y/x being greater than or equal to 0.05, preferably greater than or equal to 0.15, and the sum of x+y being greater than or equal to 0.30, preferably greater than or equal to 0.35. The invention also relates to the use of said polysaccharide in a dialysis process in order to capture at least one metal, in an MRI imaging process, in a brachytherapy process or in a process for marking foodstuffs to prevent forgeries.

公开(公告)号：US20160333251A1

公开(公告)日：2016-11-17

申请号：US15106610

申请日：2014-12-19

申请人： TOTAL SA ,  UNIVERSITE LYON 1 ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS-

发明人： Christian HURTEVENT ,  Salima BARAKA-LOKMANE ,  John-Richard ORDONEZ-VARELA ,  Olivier TILLEMENT ,  Fabien ROSSETTI ,  Mahmoud OULD METIDJI

IPC分类号： C09K8/532 ,  E21B37/06 ,  C08F12/30

CPC分类号： C09K8/532 ,  C08F12/30 ,  E21B37/06 ,  C08F212/14 ,  C08F222/02

摘要： A copolymer containing a unit including an optionally neutralised styrene sulphonic acid unit and a unit containing at least one optionally neutralised (poly)carboxylic acid unit or a (poly)amido-amine unit, to inhibit or slow the formation of sulphide deposits during the extraction of gas or oil. It also relates to a method to inhibit or slow the formation of sulphide deposits during the extraction of gas or oil, including the injection of a fluid containing the abovementioned copolymer into a wellbore, a subterranean formation or a gas or oil well.

摘要翻译： 含有包含任选中和的苯乙烯磺酸单元和含有至少一个任选中和的（多）羧酸单元或（聚）酰胺 - 胺单元的单元的单元的共聚物，以在提取期间抑制或减缓硫化物沉积物的形成 的气体或油。 它还涉及在气体或油的提取期间抑制或减缓硫化物沉积物的形成的方法，包括将含有上述共聚物的流体注入井眼，地下地层或气体或油井中。