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公开(公告)号:US09527234B2
公开(公告)日:2016-12-27
申请号:US14505310
申请日:2014-10-02
申请人: INSPIREMD, LTD
发明人: Eli Bar , Nimrod Meller , Dror Hazan
IPC分类号: B29C49/28 , B29C49/64 , A61F2/82 , A61F2/958 , B29C49/78 , G01M3/36 , B29K101/12 , B29L31/00 , A61F2/95
CPC分类号: A61F2/82 , A61F2/958 , A61F2002/9522 , A61F2002/9583 , B29C49/28 , B29C49/64 , B29C49/6409 , B29C49/783 , B29C49/786 , B29C49/80 , B29C2049/4838 , B29C2949/78151 , B29C2949/78294 , B29C2949/78436 , B29C2949/78663 , B29C2949/78949 , B29K2101/12 , B29K2905/00 , B29K2995/0013 , B29L2031/7543 , B29L2031/7546 , G01M3/3218 , G01M3/36
摘要: A medical stent mold includes a tube having an interior passage sized and dimensioned to receive a stent assembly disposed at least partially about a central portion of a stent balloon. The medical stent mold may also include a housing forming a chamber through which the tube extends. The tube may include a thermally conductive material and may have a body portion that extends within the chamber and an end portion that is proximate the body portion and that extends away from the housing. An inner diameter of the end portion of the tube is greater than an inner diameter of the body portion of the tube. Forced convection may be used to quickly heat and cool the tube. Methods of increasing retention of an expandable stent assembly on a stent balloon and of detecting a leak in a stent balloon are also included.
摘要翻译: 医疗支架模具包括具有内部通道的管道,其尺寸和尺寸被设计成接纳至少部分地围绕支架气囊的中心部分设置的支架组件。 医疗支架模具还可以包括形成腔室的壳体,管延伸穿过该腔室。 管可以包括导热材料,并且可以具有在腔室内延伸的主体部分和靠近主体部分并且远离壳体延伸的端部部分。 管的端部的内径大于管的主体部分的内径。 强制对流可用于快速加热和冷却管。 还包括增加扩张支架组件在支架气囊上的保留性并检测支架气囊中的泄漏的方法。
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公开(公告)号:US10058440B2
公开(公告)日:2018-08-28
申请号:US14500759
申请日:2014-09-29
申请人: INSPIREMD, LTD
发明人: Eli Bar , Zeev Asher Holzer , Ofir Paz
摘要: A stent assembly adapted to carotid arterial placement that includes a self-expanding support element comprising metal struts constructed to be positioned in a body lumen and expanded from a retracted state to an expanded state, and a knitted cover disposed over an exterior of the support element and along an entire length thereof, wherein the knitted cover comprises a single polymer fiber having a diameter of at least 40 nanometers to 30 microns, wherein the self-expanding support element and knitted cover together have apertures sized 20 microns to smaller than 100 microns in diameter to block larger debris when the stent assembly is placed in a carotid artery and expanded to the expanded state. Methods of stenting a carotid artery by applying the stent assembly to the carotid artery of a patient in need of treatment and expanding the stent assembly in situ are disclosed.
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公开(公告)号:US09782281B2
公开(公告)日:2017-10-10
申请号:US14592714
申请日:2015-01-08
申请人: INSPIREMD, LTD
发明人: Eli Bar , Asher Holzer , Ofir Paz
IPC分类号: A61F2/07 , A61F2/90 , A61L31/14 , A61L31/16 , A61F2/82 , C08G63/00 , C08G63/06 , C08G63/08 , C08G63/40 , C08G73/02 , C08G79/04 , A61L31/02 , A61L31/04 , A61L31/06 , A61L31/10 , A61F2/00 , A61F2/89
CPC分类号: A61F2/90 , A61F2/0063 , A61F2/07 , A61F2/82 , A61F2/89 , A61F2002/0086 , A61F2002/075 , A61F2002/823 , A61F2210/0004 , A61F2210/0076 , A61F2240/001 , A61F2250/0067 , A61L31/022 , A61L31/048 , A61L31/06 , A61L31/10 , A61L31/146 , A61L31/148 , A61L31/16 , A61L2300/604 , A61L2300/606 , A61L2420/02 , C08G63/00 , C08G63/06 , C08G63/08 , C08G63/40 , C08G73/02 , C08G79/04 , Y10T29/49964
摘要: A method of affixing a stent jacket to a stent, comprising aligning the stent jacket coaxially with the stent, placing a portion of the stent within a portion of the stent jacket, wherein a central axis of the stent is aligned with a central axis of the stent jacket, and affixing the stent jacket to the stent with a plurality of stitches, wherein the plurality of stitches form a plurality of consecutive loops that pass through one or more holes in the stent jacket and through an outer surface of the stent.
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公开(公告)号:US10258491B2
公开(公告)日:2019-04-16
申请号:US15419437
申请日:2017-01-30
申请人: InspireMD, Ltd.
发明人: Eli Bar , Dror Hazan
摘要: A stent-delivery assembly that includes a catheter; an expandable stent that is movable, relative to the catheter, from a first position to a second position; and a guidewire assembly extending through a longitudinal passage of the catheter and a longitudinal passage of the stent, the guidewire assembly being movable, relative to the catheter, from a third position to a fourth position. While the expandable stent is in the first position and while the guidewire assembly is in the third position, the stent-delivery assembly has an a-traumatic shape. While the expandable stent is in the second position and while the guidewire assembly is in the fourth position, the guidewire assembly is capable of passing through the stent to allow for retrieval of the stent-delivery assembly. Methods of use and manufacture are also included.
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公开(公告)号:US09132003B2
公开(公告)日:2015-09-15
申请号:US14314777
申请日:2014-06-25
申请人: INSPIREMD, LTD
发明人: Eli Bar , Asher Holzer , Ofir Paz
CPC分类号: A61F2/90 , A61F2/0063 , A61F2/07 , A61F2/82 , A61F2/89 , A61F2002/0086 , A61F2002/075 , A61F2002/823 , A61F2210/0004 , A61F2210/0076 , A61F2240/001 , A61F2250/0067 , A61L31/022 , A61L31/048 , A61L31/06 , A61L31/10 , A61L31/146 , A61L31/148 , A61L31/16 , A61L2300/604 , A61L2300/606 , A61L2420/02 , C08G63/00 , C08G63/06 , C08G63/08 , C08G63/40 , C08G73/02 , C08G79/04 , Y10T29/49964
摘要: A stent assembly including a stent configured to be positioned in a body lumen, and a knitted stent jacket including an expansible mesh structure having a coverage area of less than 25%, having approximate aperture diameters greater than 20 micrometers, and surrounding an external surface of the stent and coaxially associated therewith, wherein the stent assembly elutes an amount of an active pharmaceutical agent.
摘要翻译: 一种支架组件,其包括构造成定位在体腔中的支架,以及包括具有小于25%的覆盖面积的可膨胀网状结构的针织支架护套,具有大约20微米的孔径直径,并且包围 所述支架并与其共轴相关,其中所述支架组件洗脱一定量的活性药剂。
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公开(公告)号:US20140309725A1
公开(公告)日:2014-10-16
申请号:US14314777
申请日:2014-06-25
申请人: INSPIREMD, LTD
发明人: Eli Bar , Asher Holzer , Ofir Paz
CPC分类号: A61F2/90 , A61F2/0063 , A61F2/07 , A61F2/82 , A61F2/89 , A61F2002/0086 , A61F2002/075 , A61F2002/823 , A61F2210/0004 , A61F2210/0076 , A61F2240/001 , A61F2250/0067 , A61L31/022 , A61L31/048 , A61L31/06 , A61L31/10 , A61L31/146 , A61L31/148 , A61L31/16 , A61L2300/604 , A61L2300/606 , A61L2420/02 , C08G63/00 , C08G63/06 , C08G63/08 , C08G63/40 , C08G73/02 , C08G79/04 , Y10T29/49964
摘要: A stent assembly including a stent configured to be positioned in a body lumen, and a knitted stent jacket including an expansible mesh structure having a coverage area of less than 25%, having approximate aperture diameters greater than 20 micrometers, and surrounding an external surface of the stent and coaxially associated therewith, wherein the stent assembly elutes an amount of an active pharmaceutical agent.
摘要翻译: 一种支架组件,其包括构造成定位在体腔中的支架,以及包括具有小于25%的覆盖面积的可膨胀网状结构的针织支架护套,具有大约20微米的孔径直径,并且包围 所述支架并与其共轴相关,其中所述支架组件洗脱一定量的活性药剂。
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公开(公告)号:US20210137712A1
公开(公告)日:2021-05-13
申请号:US17134542
申请日:2020-12-28
申请人: INSPIREMD LTD.
发明人: Eli Bar , Zeev Asher Holzer , Ofir Paz
摘要: An enhanced stent apparatus includes an implantable element, constructed of a flexible, biocompatible material configured to be positioned in a body lumen. An inner structure is located on an inner surface of said implantable element, wherein the inner structure is made of metal, has a coverage area of less than 30% and is provided with apertures. An outer structure is located on an outer surface of said implantable element, wherein the outer structure is made of metal, has a coverage area of less than 30% and is provided with apertures.
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公开(公告)号:US10406008B2
公开(公告)日:2019-09-10
申请号:US16052301
申请日:2018-08-01
申请人: INSPIREMD, LTD.
发明人: Asher Holzer , Eli Bar , Ofir Paz
IPC分类号: A61F2/07 , A61F2/90 , A61L31/14 , A61L31/16 , A61F2/82 , C08G63/00 , C08G63/06 , C08G63/08 , C08G63/40 , C08G73/02 , C08G79/04 , A61F2/00 , A61L31/02 , A61L31/04 , A61L31/06 , A61L31/10 , A61F2/89
摘要: An intravascular device configured to treat an aneurysm that includes a support structure including metal struts configured to be positioned in a body lumen and defining a central fluid passage that extends axially along the support structure, and a knitted mesh cover disposed over an exterior thereof and across a radial arc and along a length of the support structure sufficient to exceed an opening of an aneurysm to be treated, and the cover includes a polymer fiber having a diameter of at least 40 nanometers to 30 microns and apertures therethrough, the apertures being sized to prevent blood from passing through the device to prevent further expansion of the aneurysm. Devices including apertures that are at least 20 microns and sized to minimize or prevent an aneurysm-filling material from exiting the aneurysm through the knitted mesh cover and support structure, and methods of stenting, are also encompassed.
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公开(公告)号:US10406006B2
公开(公告)日:2019-09-10
申请号:US15366703
申请日:2016-12-01
申请人: InspireMD, Ltd.
发明人: Eli Bar , Asher Holzer , Ofir Paz
IPC分类号: A61F2/07 , A61F2/90 , A61L31/14 , A61L31/16 , A61F2/82 , C08G63/00 , C08G63/06 , C08G63/08 , C08G63/40 , C08G73/02 , C08G79/04 , A61F2/00 , A61L31/02 , A61L31/04 , A61L31/06 , A61L31/10 , A61F2/89
摘要: Methods of providing a stent assembly that includes a stent jacket formed from an expansible mesh structure having apertures and that includes a fiber having a diameter of about 7 micrometers and about 40 micrometers, and an expansible stent operatively associated with the stent jacket. The method further comprises administering to the subject an active pharmaceutical ingredient (API) eluted from the stent assembly.
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公开(公告)号:US20210322187A1
公开(公告)日:2021-10-21
申请号:US17327801
申请日:2021-05-24
申请人: InspireMD Ltd.
发明人: Eli Bar , Asher Holzer , Ofir Paz
IPC分类号: A61F2/90 , A61F2/07 , A61L31/14 , A61L31/16 , A61F2/82 , C08G63/00 , C08G63/06 , C08G63/08 , C08G63/40 , C08G73/02 , C08G79/04 , A61F2/00 , A61L31/02 , A61L31/04 , A61L31/06 , A61L31/10
摘要: An intravascular device configured to treat an aneurysm that includes a support structure including metal struts configured to be positioned in a body lumen and defining a central fluid passage that extends axially along the support structure, and a knitted mesh cover disposed over an exterior thereof and across a radial arc and along a length of the support structure sufficient to exceed an opening of an aneurysm to be treated, and the cover includes a polymer fiber having a diameter of at least 40 nanometers to 30 microns and apertures therethrough, the apertures being sized to prevent blood from passing through the device to prevent further expansion of the aneurysm. Devices including apertures that are at least 20 microns and sized to minimize or prevent an aneurysm-filling material from exiting the aneurysm through the knitted mesh cover and support structure, and methods of stenting, are also encompassed.
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