公开(公告)号：US20240210392A1

公开(公告)日：2024-06-27

申请号：US18424108

申请日：2024-01-26

申请人： FUJIFILM Corporation

发明人： Hiroyasu ISHII

IPC分类号： G01N33/543 ,  B01L3/00 ,  G01N21/78

CPC分类号： G01N33/54389 ,  B01L3/5023 ,  G01N21/78 ,  B01L2200/16 ,  B01L2300/069 ,  B01L2300/0825 ,  B01L2400/0406

摘要： Provided is an assay cartridge capable of improving the throughput of the assay by shortening the time until the bubbles generated in the assay region disappear as compared with the prior art. The assay cartridge includes an assay strip that has, on the surface thereof, an assay region in which a color development state changes depending on whether a sample is positive or negative, an accommodating part that accommodates an amplifying liquid that amplifies the color development of the assay region, and the assay cartridge that is supplied from the accommodating part, an absorber that absorbs at least a part of the amplifying liquid which flows on the surface of the assay strip toward the assay region and has passed through the assay region.

公开(公告)号：US12055544B2

公开(公告)日：2024-08-06

申请号：US18455410

申请日：2023-08-24

申请人： Access Bio, Inc.

发明人： Young Ho Choi ,  Jungho Back ,  Hyoungsoo Kim ,  Hanmaru Chon ,  Myungkyu Jang ,  Hyeon Suk Kim ,  Myoun Woo Kim ,  Hyewon Park ,  Suji Lee ,  Olivia Haejeong Kim

IPC分类号： G01N33/543 ,  B01J19/00 ,  B01L3/00 ,  G01N33/569

CPC分类号： G01N33/54391 ,  B01J19/0093 ,  B01L3/5029 ,  B01L3/56 ,  G01N33/54387 ,  G01N33/54389 ,  G01N33/56983 ,  B01L2200/0668 ,  B01L2300/0609 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/0809 ,  B01L2300/0825 ,  G01N2333/08 ,  G01N2333/165 ,  G01N2469/10

摘要： Diagnostic assay devices for detecting the presence of an analyte in a sample solution may comprise a microreactor configured to form a sample solution containing the analyte, flow the sample solution therethrough in a first direction to form an analyte-capture molecule complex, and transfer the sample solution to an absorbent strip pad configured to flow therethrough, in a second direction crossing the first direction, the sample solution including the analyte-capture molecule complex and indicate a presence of the analyte-capture molecule complex. The diagnostic devices may be used, for example, to identify the presence of SARS-Cov2, RSV, influenza A, influenza B or other pathogens in samples from patients.

公开(公告)号：US20240264157A1

公开(公告)日：2024-08-08

申请号：US18434947

申请日：2024-02-07

申请人： Zhenguo Luo

发明人： Zhenguo Luo

IPC分类号： G01N33/543 ,  G01N1/02 ,  G01N21/78 ,  G01N33/52

CPC分类号： G01N33/54389 ,  G01N1/02 ,  G01N33/521 ,  G01N2001/028 ,  G01N21/78

摘要： A test device includes a base holding at least one test strip in a plane. A buffer storage container is adjacent a first end of the test strip. A top of the buffer storage container is higher than the plane of the base. A frangible seal extends across the top of the buffer storage container. A transfer passage between the top of the buffer storage container and the first end of the test strip.

公开(公告)号：US11933782B2

公开(公告)日：2024-03-19

申请号：US15677961

申请日：2017-08-15

申请人： LAWRENCE LIVERMORE NATIONAL SECURITY, LLC

发明人： Jane P. Bearinger

IPC分类号： G01N33/543 ,  G01N33/53

CPC分类号： G01N33/54388 ,  G01N33/53 ,  G01N33/54306 ,  G01N33/54366 ,  G01N33/54389 ,  C07K2317/32 ,  G01N2470/06 ,  Y10S435/97 ,  Y10S435/973

摘要： Detector systems are described, based on a primary binding compound and a secondary binding compound used in combination with a support to detect a target in a sample. The detection systems include a liquid medium hosting a first binding compound specific to a target, the first binding compound comprising a label; and a solid medium hosting a second binding compound specific to the target, the second binding compound being different from and non-competitive with respect to the first binding compound.

公开(公告)号：US20230168246A1

公开(公告)日：2023-06-01

申请号：US17536038

申请日：2021-11-28

申请人： Clas Sivertsen

发明人： Clas Sivertsen

IPC分类号： G01N33/543 ,  G01N33/569 ,  B01L3/00

CPC分类号： G01N33/54389 ,  G01N33/56983 ,  B01L3/523 ,  G01N2800/26 ,  B01L2300/069 ,  B01L2300/0825 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/0832

摘要： Embodiments of the present invention are directed to a test kit. The test kit includes an assay tube and a reagent cap. The assay tube includes a sample opening in the assay tube for receiving a sample and a lateral flow assay (“LFA”) test strip in the assay tube in communication with a sample opening. The reagent cap is designed to be placed over the assay tube and includes a buffer. When the reagent cap is placed over the sample opening of the assay tube the buffer is released over the sample to carry an analyte over the LFA test strip.

公开(公告)号：US11935657B2

公开(公告)日：2024-03-19

申请号：US17408698

申请日：2021-08-23

申请人： Reliant Immune Diagnostics, Inc.

发明人： Jovan Hutton Pulitzer ,  Henry Joseph Legere, III

IPC分类号： G06K9/00 ,  G01N33/53 ,  G01N33/543 ,  G06Q30/0251 ,  G06T7/00 ,  G16H10/65 ,  G16H50/30 ,  H04N23/60 ,  G06F3/0482

CPC分类号： G16H50/30 ,  G01N33/5302 ,  G01N33/54388 ,  G01N33/54389 ,  G01N33/54391 ,  G06Q30/0267 ,  G06Q30/0269 ,  G06T7/0014 ,  G16H10/65 ,  H04N23/64 ,  G01N2333/59 ,  G01N2333/9513 ,  G06F3/0482 ,  G06F2218/00

摘要： A system and method are provided for collection and testing of a biologic sample. The system and method comprise collecting by a user of a testing device a biologic sample for use with the testing device, assigning correlative values as test results, and receiving the test results at a server disposed on a network. Some aspects further include presenting advertisements and other messages to users through a mobile application operating on a mobile device. These aspects take into account the results of the self-diagnostic test and present different advertisements to the user based on the results of the test.

公开(公告)号：US11906515B2

公开(公告)日：2024-02-20

申请号：US16845035

申请日：2020-04-09

申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION ,  FUNDACAO OSWALDO CRUZ

发明人： Jaione Tirapu Azpiroz ,  Ademir Ferreira da Silva ,  Matheus Esteves Ferreira ,  Ricardo Luis Ohta ,  Mathias B. Steiner ,  Antonio Gomes Pinto Ferreira ,  Edimilson Domingos da Silva ,  Nara Mazarakis Rubim ,  Pedro Paulo Ferreira Ribeiro

IPC分类号： G01N33/543 ,  B01L3/00 ,  G01N33/571

CPC分类号： G01N33/54389 ,  B01L3/50273 ,  B01L3/502715 ,  G01N33/571 ,  B01L2200/10 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2400/0487

摘要： A multiplexed lateral flow device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir. The fluid distributor pad includes a paper based microfluidic element having a pattern of a hydrophobic material to distribute a portion of the sample deposition substantially equally among a plurality of flow paths. Lateral flow assays having a plurality of flow lines are aligned with flow paths of the distributor pad. An impermeable top cover has a first window arranged over the opening of the internal reservoir, and at least a second window arranged over the test results of the lateral flow assays. A housing element houses the reservoir, the distributor pad and lateral flow assays. The housing element includes an impermeable bottom cover and a spacer element arranged between the top and bottom covers and, provides a gap between the lateral flow assays and the impermeable top cover.

公开(公告)号：US20230417672A1

公开(公告)日：2023-12-28

申请号：US18253905

申请日：2021-11-22

申请人： Arizona Board of Regents on Behalf of The University of Arizona

发明人： Jeong-Yeol Yoon

IPC分类号： G01N21/64 ,  G01N33/543 ,  G01N33/569

CPC分类号： G01N21/6428 ,  G01N21/6458 ,  G01N33/54389 ,  G01N33/56983 ,  G01N2021/6439 ,  G01N2333/165

摘要： A device for detecting and/or quantifying a coronavirus comprising a paper microfluidic chip, and the use thereof.

公开(公告)号：US20230393132A1

公开(公告)日：2023-12-07

申请号：US18452029

申请日：2023-08-18

申请人： FUJIFILM Corporation

发明人： Yasutake TANAKA

IPC分类号： G01N33/543 ,  G01N21/17

CPC分类号： G01N33/54389 ,  G01N21/17 ,  G01N2021/1765

摘要： An assay apparatus includes a loading part in which a cartridge including a carrier having a spotting region and an assay region is loaded, an imaging unit that images the assay region, and a processor configured to perform a main determination, based on an assay region image, wherein the processor is configured to perform an abnormality determination for determining presence or absence of an abnormality in the assay region image, using, as a determination index, at least one of a difference between a relatively large pixel value and a relatively small pixel value in at least one column in the assay region image, a standard deviation based on the pixel values in each of the columns, or a variation coefficient based on the pixel values in each of the columns, and determine the processing content related to the main determination based on the presence or absence of the abnormality.

公开(公告)号：US20230375543A1

公开(公告)日：2023-11-23

申请号：US18319302

申请日：2023-05-17

申请人： UniQ Biotech Ltd.

发明人： Yunchuan ZHANG ,  Danyang SHEN ,  Zelin FU

IPC分类号： G01N33/543 ,  G01N33/569

CPC分类号： G01N33/54389 ,  G01N33/56983 ,  G01N2333/165

摘要： An assay system for detecting the presence or absence of at least a first analyte and a second analyte in a sample is disclosed. The assay system comprises an assay device and a separate label solution comprising a detection molecule. The assay device comprises: a first detection region for receiving the sample in a vertical direction perpendicular to a longitudinal axis; a second detection region for receiving the sample from the first detection region in a horizontal direction parallel to the longitudinal axis; a first immobilized molecule in one of the first and second detection regions configured to bind to either the detection molecule or the first analyte; and a second immobilized molecule in the other one of the first and second detection regions and configured to bind to the second analyte to generate a complex, wherein the detection molecule is configured to bind to the complex.