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公开(公告)号：US10689673B2
公开(公告)日：2020-06-23
申请号：US14367484
申请日：2012-12-21
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Paul S. Pearlman , Changlin Chen , Adriana L. Botes , Alex Van Eck Conradie , Benjamin D. Herzog
IPC: C12P7/44 , C12P13/04 , C12P17/10 , C08G69/16 , C08G69/14 , C08G69/26 , C08G69/28 , B29B9/16 , C12N9/04 , C12N9/02 , C12N9/10 , C12N9/16 , C12N9/88 , C12N9/00 , C12P7/40 , C12P7/62 , C12P13/00 , C12P7/42 , C12P13/02
Abstract: Embodiments of the present invention relate to methods for the biosynthesis of di- or trifunctional C7 alkanes in the presence of isolated enzymes or in the presence of a recombinant host cell expressing those enzymes. The di- or trifunctional C7 alkanes are useful as intermediates in the production of nylon-7, nylon-7,x, nylon-x,7, and polyesters.
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Patent Agency Ranking
公开(公告)号：US20170298396A1
公开(公告)日：2017-10-19
申请号：US15462975
申请日：2017-03-20
Applicant: INVISTA North America S.A.R.L.
Inventor： Paul S. Pearlman , Changlin Chen , Adriana L. Botes , Alex Van Eck Conradie , Benjamin D. Herzog
Abstract: Embodiments of the present invention relate to methods for the biosynthesis of di- or trifunctional C7 alkanes in the presence of isolated enzymes or in the presence of a recombinant host cell expressing those enzymes. The di- or trifunctional C7 alkanes are useful as intermediates in the production of nylon-7, nylon-7,x, nylon-x,7, and polyesters.
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公开(公告)号：US10214736B2
公开(公告)日：2019-02-26
申请号：US15593395
申请日：2017-05-12
Applicant: INVISTA North America S.A.R.L.
Inventor： Eric Althoff , Nadia Kadi , Mihai Luchian Azoitei , Yih-En A. Ban , Daniela Grabs-Röthlisberger , Alexander Pisarchik , Alexandre Zanghellini , Adriana L. Botes
IPC: C12N9/88 , A61K38/00 , C12P5/00 , C12P5/02 , C07C11/167 , C07C11/18 , C07C11/21 , C07K16/40 , C08F36/06 , C08F36/08 , C08F36/22 , G01N33/573 , C08F136/06 , C08F136/08
Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
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公开(公告)号：US20130183728A1
公开(公告)日：2013-07-18
申请号：US13715981
申请日：2012-12-14
Applicant: INVISTA North America S.a.r.l.
Inventor： Adriana L. Botes , Alex Van Eck Conradie
CPC classification number: C12N9/0008 , C12N15/52 , C12P7/18 , C12P7/42 , C12P7/44 , C12P13/001 , C12P13/005 , C12P17/10 , C12Y102/02001
Abstract: This document describes biochemical pathways for producing adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine or 1,6-hexanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups, in a C6 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on CoA-dependent elongation enzymes or analogues enzymes associated with the carbon storage pathways from polyhydroxyalkanoate accumulating bacteria.
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公开(公告)号：US10577634B2
公开(公告)日：2020-03-03
申请号：US15462975
申请日：2017-03-20
Applicant: INVISTA North America S.A.R.L.
Inventor： Paul S. Pearlman , Changlin Chen , Adriana L. Botes , Alex Van Eck Conradie , Benjamin D. Herzog
IPC: C12P7/44 , C12N9/02 , C12P13/04 , C12P17/10 , C08G69/16 , C08G69/14 , C08G69/26 , C08G69/28 , B29B9/16 , C12N9/04 , C12N9/10 , C12N9/16 , C12N9/88 , C12N9/00 , C12P7/40 , C12P7/62 , C12P13/00 , C12P7/42 , C12P13/02 , C12N9/24
Abstract: Embodiments of the present invention relate to methods for the biosynthesis of di- or trifunctional C7 alkanes in the presence of isolated enzymes or in the presence of a recombinant host cell expressing those enzymes. The di- or trifunctional C7 alkanes are useful as intermediates in the production of nylon-7, nylon-7,x, nylon-x,7, and polyesters.
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公开(公告)号：US10519433B2
公开(公告)日：2019-12-31
申请号：US15056026
申请日：2016-02-29
Applicant: INVISTA North America S.a.r.l.
Inventor： Nadia Kadi , Adriana L. Botes , Mihai Luchian Azoitei , Yih-En A. Ban , Daniela Grabs-Röthlisberger , Alexander Pisarchik , Alexandre Zanghellini , Eric Althoff
IPC: C12N9/88 , C08F136/08 , C08F136/06 , C08F36/22 , C07C11/21 , C07C11/18 , C07C11/167 , G01N33/573 , C08F36/06 , C07K16/40 , C08F36/08 , C12P5/02 , C12P5/00 , A61K38/00
Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
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