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公开(公告)号:US20060258986A1
公开(公告)日:2006-11-16
申请号:US11352916
申请日:2006-02-10
申请人: Ian Hunter , Andrew Taberner , Brian Hemond , Dawn Wendell , Nora Hogan , Nathan Ball
发明人: Ian Hunter , Andrew Taberner , Brian Hemond , Dawn Wendell , Nora Hogan , Nathan Ball
IPC分类号: A61M5/178
CPC分类号: A61M5/30 , A61D7/00 , A61M5/20 , A61M5/204 , A61M5/31525 , A61M5/31546 , A61M5/3291 , A61M5/482 , A61M5/484 , A61M2205/3561
摘要: A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.
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公开(公告)号:US20080009788A1
公开(公告)日:2008-01-10
申请号:US11351887
申请日:2006-02-10
申请人: Ian Hunter , Andrew Taberner , Brian Hemond , Dawn Wendell , Nora Hogan , Nathan Ball
发明人: Ian Hunter , Andrew Taberner , Brian Hemond , Dawn Wendell , Nora Hogan , Nathan Ball
IPC分类号: A61M5/30
CPC分类号: A61M5/3007 , A61M5/30 , A61M5/3291
摘要: A needle-free transdermal transport device for non-axially transferring a substance across a surface of a biological body includes a reservoir for holding a substance being transferred. A piston is positioned within the device in communication with the reservoir. An actuator drives the piston to expel the substance from the reservoir. The reservoir is in fluid communication with a nozzle which includes at least one lateral aperture through which the substance is expelled. Multiple lateral apertures can result in a needle-free transfer across a selectable surface area. The depth and direction of an injection can be controlled by the parameters of the nozzle. By providing a selective depth and direction, it is possible to inject a substance into a targeted biological layer, such as a cleavage plane to further promote coverage. A control source can be used to activate the device. The device can also include an optional power source.
摘要翻译: 用于不轴向转移物质穿过生物体表面的无针透皮输送装置包括用于保持被转移物质的储存器。 活塞位于与容器连通的装置内。 致动器驱动活塞将物质从贮存器排出。 储存器与喷嘴流体连通,该喷嘴包括至少一个侧向孔,物质通过该孔径排出。 多个侧向孔可导致穿过可选表面区域的无针转移。 注射的深度和方向可以通过喷嘴的参数来控制。 通过提供选择性的深度和方向,可以将物质注入目标生物层,例如劈裂平面,以进一步促进覆盖。 可以使用控制源激活设备。 该设备还可以包括可选的电源。
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公开(公告)号:US20070191758A1
公开(公告)日:2007-08-16
申请号:US11354279
申请日:2006-02-13
申请人: Ian Hunter , Andrew Taberner , Brian Hemond , Dawn Wendell , Nora Hogan , Nathan Ball
发明人: Ian Hunter , Andrew Taberner , Brian Hemond , Dawn Wendell , Nora Hogan , Nathan Ball
CPC分类号: H02K41/02 , A61B17/20 , A61B17/205 , A61D7/00 , A61M5/19 , A61M5/30 , A61M2205/50 , A61M2205/6009 , A61M2205/825 , A61M2250/00
摘要: A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.
摘要翻译: 用于将物质转移到生物体的表面上的无针透皮传送装置包括用于储存物质的储存器,与储存器流体连通的喷嘴和与储存器连通的可控电磁致动器。 称为洛伦兹力致动器的致动器包括固定磁体组件和移动线圈组件。 线圈组件移动具有位于储存器内的端部的活塞。 致动器接收电输入并且响应于相应的力产生作用在活塞上的相应的力并导致物质在储存器和生物体之间的无针转移。 力的大小,方向和持续时间由电输入动态控制(例如,伺服控制),并且可以在致动循环的过程中改变。 有利地,致动器可以根据电气输入沿不同方向移动。
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公开(公告)号:US20070129693A1
公开(公告)日:2007-06-07
申请号:US11598556
申请日:2006-11-13
申请人: Ian Hunter , Andrew Taberner , Dawn Wendell , Nora Hogan , Brian Hemond , Ching-Hua Tseng
发明人: Ian Hunter , Andrew Taberner , Dawn Wendell , Nora Hogan , Brian Hemond , Ching-Hua Tseng
IPC分类号: A61M35/00
CPC分类号: A61F9/0026 , A61F9/0017 , A61M5/30 , A61M5/31525 , A61M5/427 , A61M5/46 , A61M5/482 , A61M5/484 , A61M2005/3125 , A61M2005/31588 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/587
摘要: An eye injector for transferring a substance across the surface of the eye of an animal includes a needle-free injector and a patient positioning mechanism. The needle-free injector includes a reservoir for storing the substance to be transferred, a nozzle in fluid communication with the reservoir; and a controllable electromagnetic actuator in communication with the reservoir. The eye injector can also include a targeting light source for directing a beam of light into a pupil of the eye. The needle-free injector can be positioned adjacent to the lens of the eye, therefore producing a jet that intersects with the beam of light at a point in the retina.
摘要翻译: 用于将物质转移到动物眼睛表面的眼睛注射器包括无针注射器和患者定位机构。 无针注射器包括用于储存要转移的物质的储存器,与储存器流体连通的喷嘴; 以及与储存器连通的可控电磁致动器。 眼睛注射器还可以包括用于将光束引导到眼睛的瞳孔中的瞄准光源。 无针注射器可以定位成与眼睛的镜片相邻,因此产生与视网膜中的一点处的光束相交的射流。
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公开(公告)号:US20060058607A1
公开(公告)日:2006-03-16
申请号:US11006359
申请日:2004-12-07
申请人: Michael Garcia-Webb , Ian Hunter , Andrew Taberner
发明人: Michael Garcia-Webb , Ian Hunter , Andrew Taberner
IPC分类号: A61B5/05
CPC分类号: G01N3/38 , G01N2203/0023 , G01N2203/0051 , G01N2203/0089 , G01N2203/0222 , G01N2203/0286
摘要: An electromagnetic apparatus, comprises a conductive loop comprising two parallel conductive legs joined at a free end by a sample contacting member and a magnetic circuit that imposes a magnetic field in opposite directions across the respective legs. A method of mechanically characterizing a sample, comprises imposing a magnetic field in opposite directions in each of two parallel conductive legs of a conductive loop, the legs joined at a free end by a sample contacting member.
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