公开(公告)号：US20220002755A1

公开(公告)日：2022-01-06

申请号：US17363942

申请日：2021-06-30

Applicant: Inscripta, Inc.

Inventor： Stephen Tanner ,  Michael Graige ,  Craig Struble ,  Nandini Krishnamurthy ,  Andrea Halweg-Edwards ,  Bryan Leland ,  Simon Cawley ,  Joshua Shorenstein ,  Timothy Shaver

IPC: C12N15/90 ,  C12N15/11 ,  C12N9/22

Abstract: The present disclosure relates to compositions, methods, modules and automated integrated instrumentation to make auxiliary or ancillary edits—in addition to intended edits and immunizing edits—in cellular genomic nucleic acids in order to assess and improve nucleic acid-guided nuclease or nickase fusion editing.