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1.发明申请公开(公告)号：US20210317402A1
公开(公告)日：2021-10-14
申请号：US17355295
申请日：2021-06-23
Applicant: Inscripta, Inc.
Inventor： Eric Abbate , Katherine Krouse , Nandini Krishnamurthy , Richard Fox , Daniel Held , Michael Clay , Krishna Yerramsetty
IPC: C12N1/20 , C07K14/245
Abstract: The present disclosure relates to various different types of variants in E. coli coding and noncoding regions leading to enhanced lysine production for, e.g., supplements and nutraceuticals.
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2.发明授权公开(公告)号：US10920189B2
公开(公告)日：2021-02-16
申请号：US16904827
申请日：2020-06-18
Applicant: Inscripta, Inc.
Inventor： Richard Fox , Daniel Held , Eric Abbate , Michael Clay , Katherine Krouse , Nandini Krishnamurthy , Krishna Yerramsetty
IPC: C12N1/20 , C07K14/245
Abstract: The present disclosure relates to various different types of variants in E. coli coding and noncoding regions leading to enhanced lysine production for, e.g., supplements and nutraceuticals.
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公开(公告)号：US11787841B2
公开(公告)日：2023-10-17
申请号：US17319006
申请日：2021-05-12
Applicant: Inscripta, Inc.
Inventor： Eric Abbate , Katherine Krouse , Richard Fox , Daniel Held , Michael Clay , Nandini Krishnamurthy
IPC: A61K39/108 , C07K14/245
CPC classification number: C07K14/245 , A61K39/0258
Abstract: The present disclosure relates to various different types of mutations in the thrA gene in E. coli leading to enhanced lysine production for, e.g., supplements and nutraceuticals.
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Patent Agency Ranking
公开(公告)号：US20220002725A1
公开(公告)日：2022-01-06
申请号：US17363884
申请日：2021-06-30
Applicant: Inscripta, Inc.
Inventor： Stephen Tanner , Michael Graige , Nandini Krishnamurthy , Craig Struble
IPC: C12N15/113 , C12N9/22 , C12N15/85
Abstract: The present disclosure relates to compositions, methods, modules and automated, integrated instrumentation to enable nucleic acid-guided nuclease or nickase fusion editing in cells and correlating the edits to the resulting cellular nucleic acid profile. In some embodiments, methylated bases in a repair template are substituted for unmethylated bases in the cellular target genome and in some embodiments, unmethylated bases are substituted for methylated bases in the cellular target genome.
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5.发明授权公开(公告)号：US11078458B2
公开(公告)日：2021-08-03
申请号：US17159137
申请日：2021-01-26
Applicant: Inscripta, Inc.
Inventor： Richard Fox , Daniel Held , Eric Abbate , Michael Clay , Katherine Krouse , Nandini Krishnamurthy , Krishna Yerramsetty
IPC: C12N1/20 , C07K14/245
Abstract: The present disclosure relates to various different types of variants in E. coli coding and noncoding regions leading to enhanced lysine production for, e.g., supplements and nutraceuticals.
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6.发明申请公开(公告)号：US20220002755A1
公开(公告)日：2022-01-06
申请号：US17363942
申请日：2021-06-30
Applicant: Inscripta, Inc.
Inventor： Stephen Tanner , Michael Graige , Craig Struble , Nandini Krishnamurthy , Andrea Halweg-Edwards , Bryan Leland , Simon Cawley , Joshua Shorenstein , Timothy Shaver
Abstract: The present disclosure relates to compositions, methods, modules and automated integrated instrumentation to make auxiliary or ancillary edits—in addition to intended edits and immunizing edits—in cellular genomic nucleic acids in order to assess and improve nucleic acid-guided nuclease or nickase fusion editing.
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公开(公告)号：US20210363481A1
公开(公告)日：2021-11-25
申请号：US17319006
申请日：2021-05-12
Applicant: Inscripta, Inc.
Inventor： Eric Abbate , Katherine Krouse , Richard Fox , Daniel Held , Michael Clay , Nandini Krishnamurthy
Abstract: The present disclosure relates to various different types of mutations in the thrA gene in E. coli leading to enhanced lysine production for, e.g., supplements and nutraceuticals.
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8.发明申请公开(公告)号：US20210155894A1
公开(公告)日：2021-05-27
申请号：US17159137
申请日：2021-01-26
Applicant: Inscripta, Inc.
Inventor： Richard Fox , Daniel Held , Eric Abbate , Michael Clay , Katherine Krouse , Nandini Krishnamurthy , Krishna Yerramsetty
IPC: C12N1/20 , C07K14/245
Abstract: The present disclosure relates to various different types of variants in E. coli coding and noncoding regions leading to enhanced lysine production for, e.g., supplements and nutraceuticals.
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