专利检索 ap:("Institute for Environmental Health, Inc.") AND inv:"Timothy Kuan-Ta Lu" 第 1 页

1.

发明申请
RECOMBINANT PHAGE AND METHODS OF DETECTING LISTERIA 审中-公开

公开(公告)号：US20180274004A1

公开(公告)日：2018-09-27

申请号：US15867555

申请日：2018-01-10

申请人： Institute for Environmental Health, Inc.

发明人： Michael Sandor Koeris , Michael Cappillino , Edyta Krzymanska-Olejnik , Daniel Robert Brownell , Robert Patrick Shivers , Jayson L. Bowers , Timothy Kuan-Ta Lu

IPC分类号： C12Q1/04 , C12N7/00

CPC分类号： C12Q1/04 , C12N7/00 , C12N2795/10321 , C12N2795/10322 , C12N2795/10331 , C12N2800/22

摘要： Composition and methods for the detection of one or more target microbe(s) are provided. Compositions of the disclosure include at least one recombinant phage capable of infecting a target microbe, said phage comprising at least a capsid protein sequence, a ribosome binding site, and a codon-optimized marker. Compositions of the disclosure may further include an aqueous solution that enhances the ability to detect marker expression upon phage infection of the target microbe. In some embodiments the target microbe is Listeria.