-
公开(公告)号：US20220205968A1
公开(公告)日：2022-06-30
申请号：US17605823
申请日：2020-04-27
发明人： Mansour Samadpour
IPC分类号： G01N33/02
摘要： Provided are methods for rapid detection of microbial contaminants in fresh foods, comprising obtaining a product sample (preferably at or near the time of harvest of the product), applying, prior to any chilling of the sample or the product, an amount of a enrichment medium sufficient to cover the sample surfaces to provide a non-chilled sample for incubation, incubating the non-chilled sample for a time period and at a temperature sufficient to allow for amplification and enrichment of a non-cold-shocked target microbe, followed by recovering all or a portion of the enrichment media, concentrating the target microbes from the recovered enrichment medium, and detecting the concentrated target microbes.
-
2.发明申请TREND ANALYSIS AND STATISTICAL PROCESS CONTROL USING MULTITARGETED SCREENING ASSAYS 审中-公开使用多重筛选测试的趋势分析和统计过程控制公开(公告)号：US20150125853A1
公开(公告)日：2015-05-07
申请号：US14597733
申请日：2015-01-15
发明人： Mansour Samadpour
摘要： Aspects of the present invention provide novel multi-targeted microbiological screening and monitoring methods having substantial utility for monitoring and control of microbial growth and contaminants, microbiological processes, predictive microbiology, and for exposure and risk assessment. Microbial markers shared by both target and index microbes are used in novel methods for microbial monitoring, monitoring of microbial performance potential, trend analysis, and statistical process control (SPC) in processes or systems that are receptive to a plurality of genetically distinct microbes.
摘要翻译： 本发明的方面提供新颖的多靶点微生物筛选和监测方法，其具有用于监测和控制微生物生长和污染物，微生物过程，预测微生物学以及暴露和风险评估的实用性。 用于微生物监测，微生物性能潜力监测，趋势分析和统计过程控制（SPC）的新方法均可用于接受多种基因不同微生物的过程或系统中。
-
3.发明申请MODULAR COMPOSITING-MULTIPLE LOT SCREENING PROTOCOLS FOR DETECTION OF PATHOGENS, MICROBIAL CONTAMINANTS AND/OR CONSTITUENTS 有权用于检测病原体，微生物污染物和/或成分的模块化组合物 - 多种筛选方案公开(公告)号：US20130177920A1
公开(公告)日：2013-07-11
申请号：US13784606
申请日：2013-03-04
发明人： Mansour Samadpour
IPC分类号： G01N1/28
摘要： Particular aspects provide a method of sampling, testing and validating test lots (e.g., single-unit production lots), comprising: assembling a plurality of product portions from each of a plurality of test lots and combining the collected product portions to provide a corresponding set of test lot samples (wherein each test lot sample is attributed to a particular corresponding test lot); enriching the set of test lot samples; removing equal portions of each enriched sample, and combining the removed portions to provide a modular composite sample; and testing of the modular composite sample for the target agent/organism, wherein where such testing is positive, individual test lots may nonetheless yet be validated by further testing of a respective enriched test lot sample and obtaining a negative test result. The methods have broad utility for monitoring all sorts of test lots (e.g., environmental lots, production lots, pharmaceutical lots, etc.) and for efficiently affecting informed, targeted remedial measures.
摘要翻译： 特定方面提供了一种采样，测试和验证测试批（例如单一单位生产批）的方法，包括：从多个测试批中的每一个组装多个产品部分并组合收集的产品部分以提供相应的组 的测试批次样品（其中每个测试批样品归因于特定的相应测试批次）; 丰富了一批试样批次; 除去每个富集的样品的相等部分，并组合去除的部分以提供模块化的复合样品; 以及用于目标试剂/生物的模块化复合材料样品的测试，其中在这种测试为阳性的情况下，单个测试批可以通过进一步测试相应的富集测试批样品并获得阴性测试结果来验证。 这些方法具有广泛的用途，用于监测各种测试批（例如环境批次，生产批次，药品批次等），并有效地影响有针对性的有针对性的补救措施。
-
公开(公告)号：US11320342B2
公开(公告)日：2022-05-03
申请号：US15957804
申请日：2018-04-19
发明人： Mansour Samadpour
摘要： Disclosed are devices and methods using the devices for collecting biological and other specimens or substances from surfaces being interrogated for such contamination. Particular device aspects comprise a handle, with a frame at one end receptive to insertion and removal of a sampling medium (collecting member) intended for wiping against a surface, with the sampling member being held in place by passive projections from the frame without the need for the use of glue or articulating or moving parts. The Frame and/or the collecting member may also comprise at least one attached or integral scraping member or surface for breaking biofilms and thus making the microbes or other substances more available to being sampled by the collecting member.
-
公开(公告)号：US11219167B2
公开(公告)日：2022-01-11
申请号：US16513949
申请日：2019-07-17
发明人： Mansour Samadpour
摘要： Provided are methods for growing and shipping sprouts and microgreens in the same container, growing while in shipment using moisture provided in a water-absorbent layer, with optional added beneficials, and including methods for producing sprouts and microgreens for consumption, and for pharmaceutical/nutriceutical use, comprising growth of sprouts in retail-ready containers, the container comprising a moisture-retaining layer of agar media or the like providing water for growth and obviating the need for irrigation during sprout growth. In certain aspects, media is supplemented with beneficial organisms or additives such as probiotic microbes, vitamins (e.g., B12), cofactors, nutrients, and other items (e.g., phytochemicals, natural colors, and antioxidants) which promote the growth of the beneficial microbes on the product, and/or which become incorporated into the product. In certain aspects, added beneficial microorganisms are selected to compete/antagonize human pathogens such as Listeria, Salmonella, enterohaemorrhagic E. coli, Yersinia, and/or spoilage organisms (e.g., Erwinia, Pseudomonas and Xanthomonas).
-
公开(公告)号：US10273460B2
公开(公告)日：2019-04-30
申请号：US15087151
申请日：2016-03-31
发明人： Michael Sandor Koeris , Robert Patrick Shivers , Daniel Robert Brownell , Jason Wyatt Holder , Jayson Linn Bowers
摘要： Methods of detecting target bacteria are provided. In some embodiments, the methods comprise exposing a sample to a phage capable of infecting target bacteria, said phage comprising a heterologous nucleic acid sequence encoding a marker. In some embodiments, the target bacteria comprise Listeria. In some embodiments, the target bacteria are all Listeria. Recombinant Listeria phage comprising a heterologous nucleic acid sequence encoding a marker are also provided as are useful combinations of such phage and articles of manufacture comprising such phage, among other things.
-
7.发明申请公开(公告)号：US20180251809A2
公开(公告)日：2018-09-06
申请号：US15499719
申请日：2017-04-27
发明人： Mansour Samadpour
摘要： Particular aspects provide a method of sampling, testing and validating test lots (e.g., single-unit production lots), comprising: assembling a plurality of product portions from each of a plurality of test lots and combining the collected product portions to provide a corresponding set of test lot samples (wherein each test lot sample is attributed to a particular corresponding test lot); enriching the set of test lot samples; removing equal portions of each enriched sample, and combining the removed portions to provide a modular composite sample; and testing of the modular composite sample for the target agent/organism, wherein where such testing is positive, individual test lots may nonetheless yet be validated by further testing of a respective enriched test lot sample and obtaining a negative test result. The methods have broad utility for monitoring all sorts of test lots (e.g., environmental lots, production lots, pharmaceutical lots, etc.) and for efficiently affecting informed, targeted remedial measures.
-
公开(公告)号：US10039795B2
公开(公告)日：2018-08-07
申请号：US14707847
申请日：2015-05-08
发明人： Michael Sandor Koeris , Jayson L. Bowers , Daniel Robert Brownell , Edyta Krzymanska-Olejnik , Robert Patrick Shivers , Michael Cappillino
摘要： Composition and methods for the detection of one or more target microbe(s) are provided. Compositions of the disclosure include at least one recombinant phage capable of infecting a target microbe, said phage comprising at least a capsid protein sequence, a ribosome binding site, and a codon-optimized marker. Compositions of the disclosure may further include an aqueous solution that enhances the ability to detect marker expression upon phage infection of the target microbe. In some embodiments the target microbe include is Listeria.
-
9.发明申请MODULAR COMPOSITING-MULTIPLE LOT SCREENING PROTOCOLS FOR DETECTION OF PATHOGENS, MICROBIAL CONTAMINANTS AND/OR CONSTITUENTS 有权用于检测病原体，微生物污染物和/或成分的模块化组合物 - 多种筛选方案公开(公告)号：US20140370517A1
公开(公告)日：2014-12-18
申请号：US14472144
申请日：2014-08-28
发明人： Mansour Samadpour
摘要： Particular aspects provide a method of sampling, testing and validating test lots (e.g., single-unit production lots), comprising: assembling a plurality of product portions from each of a plurality of test lots and combining the collected product portions to provide a corresponding set of test lot samples (wherein each test lot sample is attributed to a particular corresponding test lot); enriching the set of test lot samples; removing equal portions of each enriched sample, and combining the removed portions to provide a modular composite sample; and testing of the modular composite sample for the target agent/organism, wherein where such testing is positive, individual test lots may nonetheless yet be validated by further testing of a respective enriched test lot sample and obtaining a negative test result. The methods have broad utility for monitoring all sorts of test lots (e.g., environmental lots, production lots, pharmaceutical lots, etc.) and for efficiently affecting informed, targeted remedial measures.
摘要翻译： 特定方面提供了一种采样，测试和验证测试批（例如单一单位生产批）的方法，包括：从多个测试批中的每一个组装多个产品部分并组合收集的产品部分以提供相应的组 的测试批次样品（其中每个测试批样品归因于特定的相应测试批次）; 丰富了一批试样批次; 除去每个富集的样品的相等部分，并组合去除的部分以提供模块化的复合样品; 以及用于目标试剂/生物的模块化复合材料样品的测试，其中在这种测试为阳性的情况下，单个测试批可以通过进一步测试相应的富集测试批样品并获得阴性测试结果来验证。 这些方法具有广泛的用途，用于监测各种测试批（例如环境批次，生产批次，药品批次等），并有效地影响有针对性的有针对性的补救措施。
-
10.发明授权Modular compositing-multiple lot screening protocols for detection of pathogens, microbial contaminants and/or constituents 有权用于检测病原体，微生物污染物和/或成分的模块化复合多批筛选方案公开(公告)号：US08822143B2
公开(公告)日：2014-09-02
申请号：US13784606
申请日：2013-03-04
发明人： Mansour Samadpour
IPC分类号： C12Q1/24 , C12Q1/04 , C12Q1/02 , C12Q1/68 , G01N33/533 , G01N33/535 , C12Q1/18 , G01N1/28 , C12Q1/00 , C12Q1/06 , C12Q1/08 , G01N33/53 , G01N33/573
摘要： Particular aspects provide a method of sampling, testing and validating test lots (e.g., single-unit production lots), comprising: assembling a plurality of product portions from each of a plurality of test lots and combining the collected product portions to provide a corresponding set of test lot samples (wherein each test lot sample is attributed to a particular corresponding test lot); enriching the set of test lot samples; removing equal portions of each enriched sample, and combining the removed portions to provide a modular composite sample; and testing of the modular composite sample for the target agent/organism, wherein where such testing is positive, individual test lots may nonetheless yet be validated by further testing of a respective enriched test lot sample and obtaining a negative test result. The methods have broad utility for monitoring all sorts of test lots (e.g., environmental lots, production lots, pharmaceutical lots, etc.) and for efficiently affecting informed, targeted remedial measures.
摘要翻译： 特定方面提供了一种采样，测试和验证测试批（例如单一单位生产批）的方法，包括：从多个测试批中的每一个组装多个产品部分并组合收集的产品部分以提供相应的组 的测试批次样品（其中每个测试批样品归因于特定的相应测试批次）; 丰富了一批试样批次; 除去每个富集的样品的相等部分，并组合去除的部分以提供模块化的复合样品; 以及用于目标试剂/生物的模块化复合材料样品的测试，其中在这种测试为阳性的情况下，单个测试批可以通过进一步测试相应的富集测试批样品并获得阴性测试结果来验证。 这些方法具有广泛的用途，用于监测各种测试批（例如环境批次，生产批次，药品批次等），并有效地影响有针对性的有针对性的补救措施。
-
-
-
-
-
-
-
-
-
搜索结果
27 条记录 (耗时 0.038 秒)
