公开(公告)号：US20140162318A1

公开(公告)日：2014-06-12

申请号：US13974820

申请日：2013-08-23

申请人： Institute of National Colleges of Technology, Japan ,  Nissan Chemical Industries, Ltd.

发明人： Misayo TOMURA ,  Takehisa IWAMA ,  Koichiro SARUHASHI ,  Taito NISHINO ,  Masato HORIKAWA ,  Hiroharu KAWAHARA

IPC分类号： C12P21/00

CPC分类号： C12P21/00 ,  C07K14/565 ,  C12N5/0018 ,  C12N2501/90 ,  C12N2511/00

摘要： [Summary] The present invention relates to a protein production accelerating agent that has enabled to largely increase the produced amount of a desired protein by adding polysaccharides to a medium for animal cells containing a serum or serum alternative, and a production method of a protein using a medium containing the protein production accelerating agent.

摘要翻译： 发明内容本发明涉及蛋白质生产促进剂，其能够通过向含有血清或血清替代物的动物细胞的培养基中添加多糖而大大增加所需蛋白质的产生量，以及使用 含有蛋白质生产促进剂的培养基。

公开(公告)号：US20240279597A1

公开(公告)日：2024-08-22

申请号：US18603745

申请日：2024-03-13

申请人： Nissan Chemical Industries, Ltd. ,  Kyoto University

发明人： Taito NISHINO ,  Tatsuro KANAKI ,  Ayako OTANI ,  Koichiro SARUHASHI ,  Misayo TOMURA ,  Takehisa IWAMA ,  Masato HORIKAWA ,  Norio NAKATSUJI ,  Tomomi OTSUJI

IPC分类号： C12N5/00 ,  C12N5/071 ,  C12N5/09 ,  G01N33/50

CPC分类号： C12N5/0043 ,  C12N5/005 ,  C12N5/067 ,  C12N5/0693 ,  G01N33/5011 ,  G01N33/5014 ,  G01N33/5044 ,  G01N33/5067 ,  C12N2500/14 ,  C12N2500/34 ,  C12N2531/00 ,  C12N2533/80

摘要： The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like

公开(公告)号：US20160060601A1

公开(公告)日：2016-03-03

申请号：US14784843

申请日：2014-04-16

申请人： NISSAN CHEMICAL INDUSTRIES, LTD.

发明人： Taito NISHINO ,  Tatsuro KANAKI ,  Ayako OTANI ,  Koichiro SARUHASHI ,  Misayo TOMURA

IPC分类号： C12N5/078

CPC分类号： C12N5/0641 ,  C12N2501/125 ,  C12N2501/14 ,  C12N2501/2303 ,  C12N2501/90 ,  C12N2533/70

摘要： The present invention provides a method of producing erythrocytes, including efficiently differentiating hematopoietic stem cells and/or a hematopoietic progenitor cells into erythrocytes by using a medium composition having an effect of homogeneously dispersing the hematopoietic stem cells and/or the hematopoietic progenitor cells and maintaining a floating state.

摘要翻译： 本发明提供了一种生产红细胞的方法，包括通过使用具有均匀分散造血干细胞和/或造血祖细胞的作用的培养基组合物将造血干细胞和/或造血祖细胞有效地分化成红细胞，并维持 浮动状态。