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公开(公告)号:US10195311B2
公开(公告)日:2019-02-05
申请号:US14532711
申请日:2014-11-04
Applicant: Interface Biologics, Inc.
Inventor: Roseita Esfand , J. Paul Santerre , Sylvia Tjahyadi , Bernadette Ilagan
IPC: A61L29/16 , A61M25/10 , A61L29/08 , A61K31/337 , A61K31/436 , A61L31/10 , A61L31/16 , C08G65/00 , C08L71/02 , A61K47/34 , A61K47/60 , A61K47/59 , A61K47/69
Abstract: The invention relates to oligofluorinated coatings and their use in drag delivery. The oligofluorinated coatings are compositions comprising formula (XVII). These coatings are used in a method of delivering a biologically active agent to a tissue surface in a mammalian tissue. This method occurs by contacting the surface with the coating including an oligofluorinated oligomer and a biologically active agent wherein the coating resides on the tissue surface and release the biologically active agent to the tissue surface.
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公开(公告)号:US10039864B2
公开(公告)日:2018-08-07
申请号:US15373138
申请日:2016-12-08
Applicant: Interface Biologics, Inc.
Inventor: Roseita Esfand , J. Paul Santerre , Mark J. Ernsting , H. Hung Pham , Vivian Z. Wang , Meilin Yang
IPC: A61L31/10 , C09D175/16 , A61L31/04 , C09D167/07 , C08G18/10 , C08J5/18 , C08G63/06 , C08G18/28 , C08G18/48 , C08G18/67 , C08G18/77 , C08G63/91 , C09D167/04
Abstract: The invention features oligofluorinated cross-linked polymers and their use in the manufacture of articles and coating surfaces.
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公开(公告)号:US09206283B1
公开(公告)日:2015-12-08
申请号:US14210687
申请日:2014-03-14
Applicant: Interface Biologics Inc. , AngioDynamics, Inc.
Inventor: J. Paul Santerre , Jeannette Ho , Alexandra Piotrowicz , Roseita Esfand , Raymond Lareau , Benjamin Bell
CPC classification number: A61L29/049 , A61L29/06 , C08G18/10 , C08G18/4825 , C08G18/485 , C08G18/73 , C08G18/831 , C08L75/04 , C09D175/04 , C08G18/2885
Abstract: The invention relates to admixtures of thermoplastic polyurethane base polymers that resist surface dulling and fluorinated additives and their use in the manufacture of articles, such as medical devices. For example, the admixtures of the invention are useful in the manufacture of blood dwelling medical devices, such as catheters.
Abstract translation: 本发明涉及抗表面钝化和氟化添加剂的热塑性聚氨酯基础聚合物的混合物及其在制造诸如医疗装置的制品中的用途。 例如,本发明的混合物可用于制造诸如导管的血液住院医疗装置。
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公开(公告)号:US09744269B2
公开(公告)日:2017-08-29
申请号:US14947026
申请日:2015-11-20
Applicant: Interface Biologics Inc. , AngioDynamics, Inc.
Inventor: J. Paul Santerre , Jeannette Ho , Alexandra Piotrowicz , Roseita Esfand , Raymond Lareau , Benjamin Bell
CPC classification number: A61L29/049 , A61L29/06 , C08G18/10 , C08G18/4825 , C08G18/485 , C08G18/73 , C08G18/831 , C08L75/04 , C09D175/04 , C08G18/2885
Abstract: The invention relates to admixtures of thermoplastic polyurethane base polymers that resist surface dulling and fluorinated additives and their use in the manufacture of articles, such as medical devices. For example, the admixtures of the invention are useful in the manufacture of blood dwelling medical devices, such as catheters.
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公开(公告)号:US09687597B2
公开(公告)日:2017-06-27
申请号:US15132846
申请日:2016-04-19
Applicant: Interface Biologics Inc.
Inventor: Sanjoy Mullick , Weilun Chang , Hanje Chen , Mark A. Steedman , Roseita Esfand
IPC: A61M1/36 , B01D63/02 , A61L33/06 , F16L11/04 , B01D67/00 , B01D69/02 , B01D69/08 , B01D71/44 , B01D71/68 , B29C47/00 , B29L23/00 , B29L31/00
CPC classification number: A61M1/3673 , A61L33/062 , A61M1/3672 , A61M2202/0413 , B01D63/022 , B01D63/023 , B01D67/0093 , B01D69/02 , B01D69/08 , B01D69/087 , B01D71/44 , B01D71/68 , B01D2323/30 , B01D2323/36 , B29C47/00 , B29C47/0014 , B29C47/0026 , B29L2023/00 , B29L2031/731
Abstract: The invention relates to extracorporeal blood circuits, and components thereof (e.g., hollow fiber membranes, potted bundles, and blood tubing), including 0.005% to 10% (w/w) surface modifying macromolecule. The extracorporeal blood circuits have an antithrombogenic surface and can be used in hemofiltration, hemodialysis, hemodiafiltration, hemoconcentration, blood oxygenation, and related uses.
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公开(公告)号:US09884146B2
公开(公告)日:2018-02-06
申请号:US14491324
申请日:2014-09-19
Applicant: Interface Biologics Inc.
Inventor: Sanjoy Mullick , Weilun Chang , Hanje Chen , Mark A. Steedman , Roseita Esfand
IPC: A61M1/36 , B01D63/02 , B01D67/00 , B01D69/02 , B01D69/08 , B01D71/44 , B01D71/68 , B29C47/00 , A61L33/06 , B29L23/00 , B29L31/00
CPC classification number: A61M1/3673 , A61L33/062 , A61M1/3672 , A61M2202/0413 , B01D63/022 , B01D63/023 , B01D67/0093 , B01D69/02 , B01D69/08 , B01D69/087 , B01D71/44 , B01D71/68 , B01D2323/30 , B01D2323/36 , B29C47/00 , B29C47/0014 , B29C47/0026 , B29L2023/00 , B29L2031/731
Abstract: The invention relates to extracorporeal blood circuits, and components thereof (e.g., hollow fiber membranes, potted bundles, and blood tubing), including 0.005% to 10% (w/w) surface modifying macromolecule. The extracorporeal blood circuits have an antithrombogenic surface and can be used in hemofiltration, hemodialysis, hemodiafiltration, hemoconcentration, blood oxygenation, and related uses.
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