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    Laser Surgical Apparatus and Methods of its Use Minimizing Damage During the Ablation of Tissue Using a Focused Ultrashort Pulsed Laser Beam Wherein the Slope of Fluence Breakdown is a Function of the Pulse Width
    8.
    发明申请
    Laser Surgical Apparatus and Methods of its Use Minimizing Damage During the Ablation of Tissue Using a Focused Ultrashort Pulsed Laser Beam Wherein the Slope of Fluence Breakdown is a Function of the Pulse Width 审中-公开
    激光手术设备及其使用方法使用聚焦的超短脉冲激光束消除组织中的损伤，其中Fluence Breakdown的斜率是脉冲宽度的函数

    公开(公告)号：US20150265351A1

    公开(公告)日：2015-09-24

    申请号：US14730503

    申请日：2015-06-04

    Applicant: International Business Machines Corporation

    Inventor： Richard Alan Haight ,  Peter P. Longo ,  Daniel P. Morris ,  Alfred Wagner

    IPC: A61B18/20 ,  A61F9/008 ,  A61B18/26

    CPC classification number: A61B18/20 ,  A61B18/203 ,  A61B18/26 ,  A61B2018/00577 ,  A61B2018/00625 ,  A61F9/00814 ,  A61F9/0084 ,  A61F2009/00863 ,  B23K26/0624 ,  B23K26/066 ,  B23K26/361 ,  B23K26/362 ,  B23K26/40 ,  B23K26/402 ,  B23K2103/30 ,  B23K2103/50 ,  G03F1/72

    Abstract: A laser apparatus for use in a surgical procedure including a housing forming a part of a handpiece and including interior and exterior regions. A laser cavity extending within the interior region of the housing. A cooling arrangement generating a stream of a first coolant. A precooling unit containing a second concentrated coolant. The cooling arrangement communicates with the precooling unit, so that a cooling stream having thermal calorific capacity higher than the thermal calorific capacity of the first coolant enters the laser cavity. The apparatus has a source of a beam of one or more laser pulses in which each pulse has a pulse width equal to or less than a pulse width value corresponding to a change in slope of a curve of fluence breakdown threshold (Fth) as a function of laser pulse width (T), the change occurring at a point between first and second portions of the curve, the first portion spanning a range of relatively long pulse width where Fth varies with the square root of pulse width (T½) and the second portion spanning a range of short pulse width relative to the first portion with Fth versus T slope which differs from that of the first portion; and an optical system focusing the one or more pulses of the beam to a point above the surface of the tissue to cause laser induced break down of the tissue.

    Abstract translation: 一种用于外科手术的激光装置，其包括形成手持件的一部分并且包括内部和外部区域的壳体。 在壳体的内部区域内延伸的激光腔。 产生第一冷却剂流的冷却装置。 包含第二浓缩冷却剂的预冷却单元。 冷却装置与预冷却单元连通，使得具有高于第一冷却剂的热发热量的热发热量的冷却流进入激光腔。 该装置具有一个或多个激光脉冲的光源，其中每个脉冲的脉冲宽度等于或小于对应于作为功能的注量阈值（Fth）的曲线的斜率的变化的脉冲宽度值 激光脉冲宽度（T）的变化，发生在曲线的第一和第二部分之间的点处的变化，第一部分跨越相对长的脉冲宽度的范围，其中Fth随脉冲宽度的平方根（T 1/2）而变化，而第二部分 相对于具有与第一部分不同的Fth对T斜率的第一部分的短脉冲宽度范围的部分; 以及将该束的一个或多个脉冲聚焦到组织表面上方的点的光学系统，以引起激光导致组织破裂。

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