Fully polymerized UV blocking silicone hydrogel lens
    1.
    发明授权
    Fully polymerized UV blocking silicone hydrogel lens 有权
    全聚合紫外线阻挡硅酮水凝胶镜片

    公开(公告)号:US08807745B2

    公开(公告)日:2014-08-19

    申请号:US13480648

    申请日:2012-05-25

    IPC分类号: G02B1/00

    CPC分类号: G02C7/04 G02C7/10

    摘要: A substantially fully copolymerized UV blocking hydrogel lens demonstrating sufficient blocking of UV light to meet at least FDA Class II specifications for UV blocking formed from a reaction mixture comprising at least NVP and one other comonomer and a free-radical polymerizable, substituted or unsubstituted, Bis O-hydroxy benzophenone is provided herein.

    摘要翻译: 基本上完全共聚的紫外线阻断水凝胶透镜,其表现出足够的UV光阻挡,以满足至少含有至少NVP和一种其它共聚单体的反应混合物形成的用于UV阻挡的FDA II类规格,以及可自由基聚合的,取代或未取代的双 本文提供了O-羟基二苯甲酮。

    METHOD OF MAKING A FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS
    2.
    发明申请
    METHOD OF MAKING A FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS 审中-公开
    制备全聚合紫外线阻隔硅胶水镜的方法

    公开(公告)号:US20130313733A1

    公开(公告)日:2013-11-28

    申请号:US13480651

    申请日:2012-05-25

    IPC分类号: B29D11/00 C08L79/04

    CPC分类号: G02B1/043 C08L39/06

    摘要: A method of making a substantially fully copolymerized UV blocking hydrogel lens demonstrating sufficient blocking of UV light to meet at least FDA Class II specifications for UV blocking formed from a reaction mixture comprising at least NVP and one other comonomer and a free-radical polymerizable, substituted or unsubstituted, Bis O-hydroxy benzophenone is provided herein.

    摘要翻译: 一种制备基本上完全共聚的UV阻断水凝胶透镜的方法,其显示足够的UV光阻挡,以满足至少含有至少NVP和一种其它共聚单体的反应混合物和可自由基聚合的取代基的反应混合物形成的用于UV阻断的FDA II类规格 或未取代的双O-羟基二苯甲酮。

    FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS

    公开(公告)号:US20130314663A1

    公开(公告)日:2013-11-28

    申请号:US13480648

    申请日:2012-05-25

    IPC分类号: G02C7/04

    CPC分类号: G02C7/04 G02C7/10

    摘要: A substantially fully copolymerized UV blocking hydrogel lens demonstrating sufficient blocking of UV light to meet at least FDA Class II specifications for UV blocking formed from a reaction mixture comprising at least NVP and one other comonomer and a free-radical polymerizable, substituted or unsubstituted, Bis O-hydroxy benzophenone is provided herein.

    High Refractive Index Lenses
    5.
    发明申请
    High Refractive Index Lenses 审中-公开
    高折射率镜片

    公开(公告)号:US20120329905A1

    公开(公告)日:2012-12-27

    申请号:US13483397

    申请日:2012-05-30

    CPC分类号: C07C333/04

    摘要: An optical copolymer comprising: a constituent derived from a sulfated lens monomer of general formula I [PG-R1—NHC(Y)S—R2]n—R3  I PG is a polymerizable group selected from the group consisting of vinyl, acryloyl, acryoyloxy, methacryoyl and methacryoyloxy; acrylamido and methacrylamido; Y is oxygen or sulfur; and n is 2, 3 or 4. Also, R1 is an organic group of one to eight carbon atoms and optionally with one or more oxygen atoms or an aromatic ring. R2 is a bond or an organic group of one to six carbon atoms. R3 is a bond, an organic group of one to ten carbons atoms, carbon, oxygen, sulfur or a disulfide; and a lens monomer. The sulfated lens monomer is derived from a first component of formula, PG-R1—NC(Y), and a polythiol of formula, R3—[R2—SH]n.

    摘要翻译: 一种光学共聚物,其包含:衍生自通式I的硫酸化透镜单体的组分[PG-R 1 -NHC(Y)S-R 2] n -R 3 I PG是选自乙烯基,丙烯酰基,丙烯酰氧基 ,甲基丙烯酰基和甲基丙烯酰氧基; 丙烯酰胺和甲基丙烯酰胺; Y是氧或硫; n为2,3或4.另外,R 1为碳原子数为1〜8的有机基团,且可以具有一个以上的氧原子或芳香环。 R2是1-6个碳原子的键或有机基团。 R3是一个键,一至十个碳原子的有机基团,碳,氧,硫或二硫键; 和透镜单体。 硫酸化透镜单体衍生自式的第一组分PG-R1-NC(Y)和式R3- [R2-SH] n的多硫醇。

    Recombinantly modified plasmin
    6.
    发明授权
    Recombinantly modified plasmin 有权
    重组修饰的纤溶酶

    公开(公告)号:US08420079B2

    公开(公告)日:2013-04-16

    申请号:US13223373

    申请日:2011-09-01

    IPC分类号: A61K38/48 C12N9/50 A01N43/04

    CPC分类号: C12N9/6435 C12Y304/21007

    摘要: Polynucleotides and polypeptides relating to a recombinantly-modified plasmin(ogen) molecule are provided. The plasmin(ogen) molecule has a single kringle domain N-terminal to the activation site present in the native human plasminogen molecule, and exhibits lysine-binding and significant enzymatic characteristics associated with the native enzyme.

    摘要翻译: 提供了与重组修饰的纤溶酶(原)分子相关的多核苷酸和多肽。 纤溶酶原(Ogen)分子在天然人纤溶酶原分子中存在活化位点的N-末端单个三环结构域,并显示与天然酶相关的赖氨酸结合和显着的酶特征。

    SYSTEM AND METHOD FOR UNIFORMLY PRICING ITEMS
    7.
    发明申请
    SYSTEM AND METHOD FOR UNIFORMLY PRICING ITEMS 审中-公开
    用于均匀定价项目的系统和方法

    公开(公告)号:US20120078817A1

    公开(公告)日:2012-03-29

    申请号:US13315857

    申请日:2011-12-09

    IPC分类号: G06Q30/00

    摘要: A computer-assisted method for uniformly pricing chargeable items in a healthcare provider's chargeable item database is disclosed. The method applies uniform pricing to identical or related chargeable items. A system for uniformly pricing related chargeable items is also disclosed.

    摘要翻译: 公开了一种在医疗保健提供者的可收费项目数据库中统一定价收费项目的计算机辅助方法。 该方法将统一定价适用于相同或相关的应付项目。 还披露了统一定价相关费用项目的系统。