-
1.发明授权Isolating a mammalian embryonic stem cell from a homogenous pluripotent outgrowth of a mammalian pre-implantation embryo 有权将哺乳动物胚胎干细胞从哺乳动物植入前胚胎的均质多能生长中分离出来公开(公告)号：US09499785B2
公开(公告)日：2016-11-22
申请号：US12446801
申请日：2007-10-24
Applicant: Ivan Vassiliev , Mark Brenton Nottle
Inventor： Ivan Vassiliev , Mark Brenton Nottle
IPC: C12N15/00 , C12N5/073 , C12N5/0735
CPC classification number: C12N5/0606 , C12N5/0604 , C12N2500/25 , C12N2500/32 , C12N2500/40 , C12N2500/44 , C12N2500/84 , C12N2500/90 , C12N2501/11 , C12N2501/115 , C12N2501/235 , C12N2502/13
Abstract: The present invention provides a method of isolating a pluripotent cell from a pre-implantation embryo without isolation of the pluripotent cells from other cells, the method including propagating a whole pre-implantation embryo including one or more pluripotent cells, embedded in a feeder cell layer and cultivated in a medium substantially free of serum, and isolating a pluripotent cell from the one or more pluripotent cells. The present invention also provides pluripotent cells generated by the method and uses thereof.
Abstract translation: 本发明提供了从植入前的胚胎中分离多能细胞而不从其它细胞分离多能细胞的方法，所述方法包括传播包含一个或多个多能细胞的整个植入前胚胎，其嵌入饲养细胞层 并在基本上不含血清的培养基中培养，并从一个或多个多能细胞中分离出多能细胞。 本发明还提供通过其方法和用途产生的多能细胞。
-
2.发明申请公开(公告)号：US20100017899A1
公开(公告)日：2010-01-21
申请号：US12446801
申请日：2007-10-24
Applicant: Ivan Vassiliev , Mark Brenton Nottle
Inventor： Ivan Vassiliev , Mark Brenton Nottle
IPC: A01K67/027 , C12N5/02 , C12N5/00
CPC classification number: C12N5/0606 , C12N5/0604 , C12N2500/25 , C12N2500/32 , C12N2500/40 , C12N2500/44 , C12N2500/84 , C12N2500/90 , C12N2501/11 , C12N2501/115 , C12N2501/235 , C12N2502/13
Abstract: The present invention provides a method of isolating a pluripotent cell from a pre-implantation embryo without isolation of the pluripotent cells from other cells, the method including propagating a whole pre-implantation embryo including one or more pluripotent cells, embedded in a feeder cell layer and cultivated in a medium substantially free of serum, and isolating a pluripotent cell from the one or more pluripotent cells. The present invention also provides pluripotent cells generated by the method and uses thereof.
Abstract translation: 本发明提供了从植入前的胚胎中分离多能细胞而不从其它细胞分离多能细胞的方法，所述方法包括传播包含一个或多个多能细胞的整个植入前胚胎，其嵌入饲养细胞层 并在基本上不含血清的培养基中培养，并从一个或多个多能细胞中分离出多能细胞。 本发明还提供通过其方法和用途产生的多能细胞。
-
3.发明申请Method for Producing Stem Cells or Stel Cell-Like Cells from Mammalian Embryos 审中-公开从哺乳动物胚胎中产生干细胞或细胞样细胞样细胞的方法公开(公告)号：US20100138947A1
公开(公告)日：2010-06-03
申请号：US11919597
申请日：2006-04-28
Applicant: Ivan Vassiliev , Paul John Verma
Inventor： Ivan Vassiliev , Paul John Verma
IPC: C12N15/873 , A61D19/00 , C12N5/0735 , A61K45/00 , A61P39/00
CPC classification number: C12N5/0606 , A01K2227/101 , A01K2227/105 , C12N15/873 , C12N15/877 , C12N2500/44 , C12N2501/06 , C12N2501/11 , C12N2501/115 , C12N2501/16 , C12N2501/235 , C12N2502/13 , C12N2509/00
Abstract: The present invention relates to methods and compositions for the production and derivation of pluripotent stem cells from embryos or embryo-derived cells and therapeutic uses therefor. In particular, the present invention relates to a method for producing functional stem cells or stem cell-like cells comprising the steps of culturing an embryo or embryo-derived cells in the presence of a demethylation agent and isolating functional pluripotent cells.
Abstract translation: 本发明涉及用于从胚胎或胚胎衍生的细胞产生和衍生多能干细胞的方法和组合物及其治疗用途。 具体而言，本发明涉及一种功能性干细胞或干细胞样细胞的制造方法，其特征在于，包括在去甲基化剂存在下培养胚胎或来源于细胞的细胞并分离功能性多能细胞的步骤。
-
-
Search Results
3
records
(took 0.015 seconds)
