公开(公告)号：US20200291121A1

公开(公告)日：2020-09-17

申请号：US16753488

申请日：2018-10-02

Applicant: JOINT STOCK COMPANY "BIOCAD"

Inventor： Ekaterina Vladimirovna SOFRONOVA ,  Aleksei Konstantinovich MISORIN ,  Aleksandr Nikolaevich DORONIN ,  Timofey Aleksandrovich NEMANKIN ,  Aleksandra Aleksandrovna SOZONOVA ,  Galina Stepanovna ZHIRIVSKAIA ,  Sergey Aleksandrovich LEGOTSKY ,  Anna Konstantinovna VLADIMIROVA ,  Alina Valerevna BELIASNIKOVA ,  Mariia Aleksandrovna SHCHEMELEVA ,  Pavel Andreevich IAKOVLEV ,  Valery Vladimirovich SOLOVYEV ,  Elena Andreevna KRENDELEVA ,  Natalia Evgenevna PESTOVA ,  Dmitry Valentinovich MOROZOV

IPC: C07K16/28 ,  C12N15/64

Abstract: The present invention relates to biotechnology and provides antibodies that specifically bind to IL-5Rα. The invention also relates to DNA encoding said antibodies, the corresponding expression vectors and methods of production thereof, as well as methods of treatment using said antibodies.

公开(公告)号：US20220089761A1

公开(公告)日：2022-03-24

申请号：US17288234

申请日：2019-10-30

Applicant: JOINT STOCK COMPANY "BIOCAD"

Inventor： Pavel Andreevich IAKOVLEV ,  Natalia Eugenievna PESTOVA ,  Arina Vitalevna ANIKINA ,  Anna Alexandrovna TRUDOVISHNIKOVA ,  Mariia Aleksandrovna SHCHEMELEVA ,  Nina Grachyaevna KHARATIAN ,  Valery Vladimirovich SOLOVYEV ,  Alexey Konstantinovich MISORIN ,  Sergei Vasilyevich DIDUK ,  Anna Vladimirovna EROSHOVA ,  Veronika Sergeevna USATOVA ,  Elena Andreevna KRENDELEVA ,  Iakov Iurevich USTIUGOV ,  Aleksei Aleksandrovich ALEKSANDROV ,  Iana Andreevna SMIRNOVA ,  Svetlana Vladimirovna KOSKOVA ,  Roman Alekseevich IVANOV ,  Dmitry Valentinovich MOROZOV

IPC: C07K16/28 ,  A61P35/02 ,  C12N15/63

Abstract: The present invention relates to biotechnology and provides a monoclonal antibody that specifically binds to CD20. The invention also relates to DNA encoding said antibody, the corresponding expression vectors and methods of production thereof, as well as methods of treatment using said antibody.