公开(公告)号：US20240034764A1

公开(公告)日：2024-02-01

申请号：US18266001

申请日：2021-12-10

Applicant: JOINT STOCK COMPANY "BIOCAD"

Inventor： Aleksey Vladimirovich KONONOV ,  Iuliia Viktorovna EVDOKIMOVSKAIA ,  Iana Andreevna SMIRNOVA ,  Stanislav Rudolfovich EVDOKIMOV ,  Elena Sergeevna KOLOSOVA ,  Sergei Andreevich AGEEV ,  Vladimir Sergeevich TSYMPILOV ,  Valery Vladimirovich SOLOVYEV ,  Pavel Andreevich IAKOVLEV ,  Dmitry Valentinovich MOROZOV

IPC: C07K14/54 ,  C12N15/63 ,  A61P35/00 ,  C07K16/28

CPC classification number: C07K14/5428 ,  C12N15/63 ,  A61P35/00 ,  C07K16/2818 ,  C07K2319/30

Abstract: The present invention relates to the field of biotechnology and medicine, in particular to an immunocytokine for activating the human IL-10Rα receptor. The invention further relates to nucleic acids encoding said immunocytokine, expression vectors, host cells and methods for producing same, methods for producing the immunocytokine, pharmaceutical compositions comprising the above immunocytokine, pharmaceutical compositions comprising the above immunocytokine and other therapeutically active compounds, methods for treating an oncological disease and the uses of the immunocytokine or pharmaceutical compositions thereof for treating an oncological disease.

公开(公告)号：US20220089761A1

公开(公告)日：2022-03-24

申请号：US17288234

申请日：2019-10-30

Applicant: JOINT STOCK COMPANY "BIOCAD"

Inventor： Pavel Andreevich IAKOVLEV ,  Natalia Eugenievna PESTOVA ,  Arina Vitalevna ANIKINA ,  Anna Alexandrovna TRUDOVISHNIKOVA ,  Mariia Aleksandrovna SHCHEMELEVA ,  Nina Grachyaevna KHARATIAN ,  Valery Vladimirovich SOLOVYEV ,  Alexey Konstantinovich MISORIN ,  Sergei Vasilyevich DIDUK ,  Anna Vladimirovna EROSHOVA ,  Veronika Sergeevna USATOVA ,  Elena Andreevna KRENDELEVA ,  Iakov Iurevich USTIUGOV ,  Aleksei Aleksandrovich ALEKSANDROV ,  Iana Andreevna SMIRNOVA ,  Svetlana Vladimirovna KOSKOVA ,  Roman Alekseevich IVANOV ,  Dmitry Valentinovich MOROZOV

IPC: C07K16/28 ,  A61P35/02 ,  C12N15/63

Abstract: The present invention relates to biotechnology and provides a monoclonal antibody that specifically binds to CD20. The invention also relates to DNA encoding said antibody, the corresponding expression vectors and methods of production thereof, as well as methods of treatment using said antibody.