Pyrazolo[1,5-A]pyrimidine-carbonyl-piperazine derivatives
    1.
    发明授权
    Pyrazolo[1,5-A]pyrimidine-carbonyl-piperazine derivatives 有权
    吡唑并[1,5-A]嘧啶 - 羰基 - 哌嗪衍生物

    公开(公告)号:US08093249B2

    公开(公告)日:2012-01-10

    申请号:US12503135

    申请日:2009-07-15

    IPC分类号: A61K31/497 C07D487/00

    CPC分类号: C07D487/04

    摘要: The present invention relates to novel piperazine derivatives; to processes for their preparation; to pharmaceutical compositions containing the derivatives; and to the use of the derivatives in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial.

    摘要翻译: 本发明涉及新的哌嗪衍生物; 进行准备; 含有该衍生物的药物组合物; 以及在治疗中使用衍生物治疗阻断Cav2.2钙通道有益的疾病。

    Disinfectant Materials and Methods
    8.
    发明申请
    Disinfectant Materials and Methods 有权
    消毒剂材料与方法

    公开(公告)号:US20120301556A1

    公开(公告)日:2012-11-29

    申请号:US13576224

    申请日:2011-02-03

    申请人: David Norton

    发明人: David Norton

    IPC分类号: A01N59/00 A01P1/00

    摘要: A disinfectant combination comprises a first supply of a water-soluble hypochlorite; and a second supply of at least one saturated, water-soluble, physiologically acceptable carboxylic acid in solution in an alcoholic solvent which comprises ethanol and optionally water. The combination is used in a method of disinfection, in which a dosed amount of the first supply is mixed with a dosed amount of the second supply to form a disinfectant in situ, and the resulting combined solution, optionally diluted with further water, is applied to a surface or article to be disinfected. In a preferred embodiment, the combination is used for disinfection of endoscopes.

    摘要翻译: 消毒剂组合包括第一次供应水溶性次氯酸盐; 以及在包含乙醇和任选的水的醇溶剂中在溶液​​中第二次供应至少一种饱和的水溶性生理上可接受的羧酸。 该组合用于消毒方法,其中将第一供应量的剂量与定量量的第二供应物混合以原位形成消毒剂,并且将所得到的组合溶液任选地用另外的水稀释, 到要消毒的表面或物品。 在优选实施例中,该组合用于消毒内窥镜。

    PRML based magnetic servo position demodulator
    9.
    发明申请
    PRML based magnetic servo position demodulator 有权
    基于PRML的磁伺服位置解调器

    公开(公告)号:US20070019316A1

    公开(公告)日:2007-01-25

    申请号:US11188199

    申请日:2005-07-22

    申请人: David Norton

    发明人: David Norton

    IPC分类号: G11B20/08

    摘要: Apparatuses and methods for detecting reference marks on magnetic data storage mediums are described herein. In one variation, the apparatus comprises a magnetic servo position demodulator operable to extract information from the magnetic data storage medium utilizing Partial Response/Maximum Likelihood (PRML) technique. Synchronization marks stored within the PRML channel is then detected utilizing a digital filter. For each of the detected synchronization mark, a further refined position of the synchronization mark can be determined utilizing a mathematical prediction model.

    摘要翻译: 这里描述了用于检测磁性数据存储介质上的参考标记的装置和方法。 在一个变型中,该装置包括一个磁性伺服位置解调器,可操作以使用部分响应/最大似然(PRML)技术从磁数据存储介质中提取信息。 然后使用数字滤波器检测存储在PRML通道内的同步标记。 对于每个检测到的同步标记,可以使用数学预测模型来确定同步标记的进一步细化位置。