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    Methods and compounds for the treatment of immunologically-mediated diseases using mycobacterium vaccae
    2.
    发明授权
    Methods and compounds for the treatment of immunologically-mediated diseases using mycobacterium vaccae 失效
    使用分枝杆菌疫苗治疗免疫介导的疾病的方法和化合物

    公开(公告)号：US06350457B1

    公开(公告)日：2002-02-26

    申请号：US09449013

    申请日：1999-11-24

    申请人： James D. Watson ,  Paul L. J. Tan ,  Ross Prestidge

    发明人： James D. Watson ,  Paul L. J. Tan ,  Ross Prestidge

    IPC分类号： A61K3904

    CPC分类号： A61K35/74 ,  A61K39/04

    摘要： Methods for the prevention and treatment of disorders, including disorders of the respiratory system, such as infection with mycobacteria such as M. tuberculosis or M. avium, sarcoidosis, asthma, allergic rhinitis and lung cancers are provided, such methods comprising administering a composition comprising derivatives of delipidated and deglycolipidated M vaccae cells.

    摘要翻译： 提供了预防和治疗疾病的方法，包括呼吸系统疾病，例如分枝杆菌感染如结核分枝杆菌或鸟分枝杆菌，结节病，哮喘，过敏性鼻炎和肺癌，所述方法包括给予包含 脱脂和去糖脂化的M疫苗细胞的衍生物。

    Methods for the treatment of immunologically-mediated skin disorders
    3.
    发明授权
    Methods for the treatment of immunologically-mediated skin disorders 失效
    用于治疗免疫介导的皮肤病的方法

    公开(公告)号：US06328978B1

    公开(公告)日：2001-12-11

    申请号：US09324542

    申请日：1999-06-02

    申请人： James D. Watson ,  Paul L. J. Tan ,  Ross Prestidge

    发明人： James D. Watson ,  Paul L. J. Tan ,  Ross Prestidge

    IPC分类号： A61K4500

    CPC分类号： C07K14/35 ,  A61K38/00 ,  A61K39/00 ,  A61K39/04 ,  A61K48/00 ,  A61K2039/51 ,  C07K2319/00 ,  Y10S514/863 ,  Y10S514/885 ,  Y10S514/886 ,  Y10S530/825

    摘要： Methods for the treatment of skin disorders, including psoriasis, atopic dermatitis, allergic contact dermatitis, alopecia areata and skin cancers are provided, such methods comprising administering a composition having antigenic and/or adjuvant properties. Compositions which may be usefully employed in the inventive methods include inactivated M. vaccae cells, delipidated and deglycolipidated M. vaccae cells, M. vaccae culture filtrate and compounds present in or derived therefrom, together with combinations of such compositions.

    摘要翻译： 提供了治疗皮肤病，包括牛皮癣，特应性皮炎，过敏性接触性皮炎，斑秃和皮肤癌的方法，所述方法包括给予具有抗原和/或佐剂性质的组合物。 可有效地用于本发明方法的组合物包括灭活的M.疫苗细胞，脱脂和去糖脂化的疫苗接种细胞，疫苗接种培养物滤液以及存在于其中或由其衍生的化合物，以及这些组合物的组合。

    Eraser assemblies and methods of manufacturing same
    6.
    发明授权
    Eraser assemblies and methods of manufacturing same 失效
    橡皮组件及其制造方法

    公开(公告)号：US08243028B2

    公开(公告)日：2012-08-14

    申请号：US12138759

    申请日：2008-06-13

    申请人： Peter W. Hildebrandt ,  James D. Watson ,  Ning Hui

    发明人： Peter W. Hildebrandt ,  James D. Watson ,  Ning Hui

    IPC分类号： G06F3/041

    CPC分类号： G06F3/0321

    摘要： An eraser assembly for erasing a display surface of an electronic display system, where the display surface can implement a dot pattern. The eraser assembly can comprise a body assembly, which can be in communication with an eraser pad and a sensing device, such as a camera. The camera can be adapted to view the display surface when the eraser pad is in use.

    摘要翻译： 一种用于擦除电子显示系统的显示表面的橡皮擦组件，其中显示表面可以实现点图案。 橡皮擦组件可以包括主体组件，其可以与橡皮擦垫和感测装置（例如相机）连通。 当使用橡皮擦垫时，相机可以适用于查看显示表面。

    Automatic Projection Calibration
    8.
    发明申请
    Automatic Projection Calibration 审中-公开
    自动投影校准

    公开(公告)号：US20080192017A1

    公开(公告)日：2008-08-14

    申请号：US11911185

    申请日：2005-04-11

    申请人： Peter W. Hildebrandt ,  Scott Wilson ,  James D. Watson ,  Brent W. Anderson ,  Neal A. Hofmann ,  Brand C. Kvavle ,  Jeffrey P. Hughes ,  Joseph Hubert

    发明人： Peter W. Hildebrandt ,  Scott Wilson ,  James D. Watson ,  Brent W. Anderson ,  Neal A. Hofmann ,  Brand C. Kvavle ,  Jeffrey P. Hughes ,  Joseph Hubert

    IPC分类号： G09G5/10 ,  G09G3/36

    CPC分类号： G09G3/002 ,  G06F3/0418 ,  G09G2320/0693 ,  G09G2360/14 ,  H04N9/3185 ,  H04N9/3194

    摘要： The present invention is a whiteboard method and system (100) having automated projection calibration that does not require user interaction. The method and system are accomplished by placing sensors (302) beneath a target surface and projecting a projected pattern to discover a geometric correspondence between the target surface and the projecting device. Optical sensors (32) are preferably employed to sense the presence of the projected pattern on the whiteboard. The input data is used with a mapping function or translation matrix for converting whiteboard coordinates to screen coordinates, which are then used for mapping the coordinates to a cursor position. When the geometry of the whiteboard surface is known, and the locations of the optical sensors within this geometry are known, the information about which projector pixels illuminate which sensor can be used to calibrate the projecting device with respect to the whiteboard.

    摘要翻译： 本发明是具有不需要用户交互的自动投影校准的白板方法和系统（100）。 该方法和系统通过将传感器（302）放置在目标表面下方并且投影投影图案以发现目标表面和投影装置之间的几何对应来实现。 优选使用光学传感器（32）来感测白板上的投影图案的存在。 输入数据与映射函数或转换矩阵一起使用，用于将白板坐标转换为屏幕坐标，然后将其用于将坐标映射到光标位置。 当白板表面的几何形状是已知的，并且光学传感器在该几何形状内的位置是已知的时候，关于哪个投影仪像素照亮哪个传感器可用于相对于白板校准投影设备的信息。

    SLIDABLE ELECTRONIC WHITEBOARD SYSTEM
    9.
    发明申请
    SLIDABLE ELECTRONIC WHITEBOARD SYSTEM 审中-公开
    可滑动电子白板系统

    公开(公告)号：US20080165137A1

    公开(公告)日：2008-07-10

    申请号：US11775487

    申请日：2007-07-10

    申请人： Sudhakar S. LAHADE ,  James D. Watson ,  Mark A. Zeh ,  Michael H. Dunn ,  Peter W. Hildebrandt

    发明人： Sudhakar S. LAHADE ,  James D. Watson ,  Mark A. Zeh ,  Michael H. Dunn ,  Peter W. Hildebrandt

    IPC分类号： G09G5/00

    CPC分类号： G06F1/1601 ,  G06F3/041

    摘要： The present invention provides movable visual communication systems, more specifically movable electronic whiteboard systems. The invention provides an electronic whiteboard having at least one positioning member and a guide element adapted to receive the positioning member, wherein the electronic whiteboard and the positioning member are movable along the guide element. The guide element can house an extendable or retractable line that maintains connectivity with the electronic whiteboard along the guide element.

    摘要翻译： 本发明提供了可移动视觉通信系统，更具体地说是可动电子白板系统。 本发明提供一种电子白板，其具有至少一个定位构件和适于容纳定位构件的引导元件，其中电子白板和定位构件可沿导向元件移动。 引导元件可以容纳可延伸或可缩回的线，其沿着引导元件保持与电子白板的连接。

    Methods for the preservation of cells and tissues using trimethylamine oxide or betaine with raffinose or trehalose
    10.
    发明授权
    Methods for the preservation of cells and tissues using trimethylamine oxide or betaine with raffinose or trehalose 失效
    使用三甲胺氧化物或甜菜碱与棉子糖或海藻糖保存细胞和组织的方法

    公开(公告)号：US5827640A

    公开(公告)日：1998-10-27

    申请号：US722306

    申请日：1996-09-30

    申请人： Philippa M. Wiggins ,  Alexander B. Ferguson ,  James D. Watson

    发明人： Philippa M. Wiggins ,  Alexander B. Ferguson ,  James D. Watson

    IPC分类号： A01N1/02 ,  C12N1/04

    CPC分类号： A01N1/02 ,  A01N1/0221 ,  C12N1/04

    摘要： The present invention provides solutions and methods for preserving biological material that enable organs, tissues and cells to be stored for extended periods of time with minimal loss of biological activity. The inventive solutions are substantially isotonic with the biological material to be preserved and are substantially free of univalent oxyanions and of iodide. The solutions comprise a first neutral solute having a molecular weight of at least about 335 and a solubility in water of at least about 0.3M, and a second neutral solute having a molecular weight of less than about 200 and having both hydrophilic and hydrophobic moieties. The inventive solutions preferably contain CaSO.sub.4, together with combinations of anions and cations from the protein-stabilizing ends of the Hofmeister series, such as K.sub.2 SO.sub.4. In particular methods using solutions comprising raffinose or trehalose and trimethyl amine oxide or betaine, wherein the solution is substantially isotonic with the biological material and the solution is substantially free of iodide, dihydrogen phosphate, bicarbonate, nitrate and bisulfate are described.

    摘要翻译： 本发明提供了用于保存生物材料的方法和方法，所述生物材料能够使器官，组织和细胞长时间储存​​，同时生物活性损失最小。 本发明的溶液与待保存的生物材料基本上是等渗的，并且基本上不含一价的氧阴离子和碘化物。 溶液包含分子量至少为约335且在水中的溶解度至少为约0.3M的第一中性溶质和分子量小于约200的第二中性溶质，并具有亲水和疏水部分。 本发明的溶液优选含有CaSO 4，以及来自Hofmeister系列的蛋白质稳定末端的阴离子和阳离子的组合，例如K 2 SO 4。 特别是使用包含棉子糖或海藻糖和三甲基氧化胺或甜菜碱的溶液的方法，其中所述溶液与生物材料基本上是等渗的，并且溶液基本上不含碘化物，磷酸二氢盐，碳酸氢盐，硝酸盐和硫酸氢盐。