公开(公告)号：US06689615B1

公开(公告)日：2004-02-10

申请号：US09679130

申请日：2000-10-04

申请人： James Murto ,  Michael Salvati

发明人： James Murto ,  Michael Salvati

IPC分类号： G01N3386

CPC分类号： B03C1/01 ,  B03C1/286 ,  G01N33/491 ,  G01N33/5002 ,  Y10S436/806 ,  Y10S436/815 ,  Y10S436/817 ,  Y10S436/818 ,  Y10S436/824 ,  Y10S436/827 ,  Y10T436/106664 ,  Y10T436/25375 ,  Y10T436/255

摘要： Approaches are described for separating plasma from whole blood samples and include the use of magnetically attractable particles associated with an agglutinating agent. The magnetically attractable particles bind the cellular components in a whole blood sample. Application of a magnetic field gradient to a container with the blood sample and the magnetically attractable particles draws the particles to the surface of the container near the source of the magnetic field gradient. The plasma can be removed and stored or used for monitoring or detecting analytes in the plasma.

摘要翻译： 描述了用于从全血样品中分离血浆的方法，并且包括使用与凝集剂相关的磁吸引颗粒。 磁吸引颗粒结合全血样品中的细胞组分。 将磁场梯度施加到具有血液样品和可磁吸引颗粒的容器中将颗粒吸引到容器的靠近磁场梯度源的表面。 等离子体可以被去除并存储或用于监测或检测等离子体中的分析物。

公开(公告)号：US20130144323A1

公开(公告)日：2013-06-06

申请号：US13310503

申请日：2011-12-02

申请人： Howard Root ,  James Murto ,  Stephen Penegor ,  Gregg Sutton

发明人： Howard Root ,  James Murto ,  Stephen Penegor ,  Gregg Sutton

IPC分类号： A61M29/04

CPC分类号： A61B17/12109 ,  A61B17/12031 ,  A61B17/1219 ,  A61B2017/00429 ,  A61B2017/00526 ,  A61B2017/00889 ,  A61B2017/00893 ,  A61B2017/00898 ,  A61B2017/00942 ,  A61B2017/1205 ,  A61B2017/12054 ,  A61L31/044 ,  A61L31/045 ,  A61L31/146 ,  A61L31/16 ,  A61L2300/404 ,  A61L2430/36 ,  F04C2270/041

摘要： Assemblies, kits, and methods for occluding a vascular vessel, such as a varicose vein, are disclosed. An assembly can include a removable inner member, a removable outer member, and an elongated expandable member positioned in a compressed form between portions of the inner and outer members. To facilitate their removal, one or both of the inner and outer members can include a handle coupled to a proximal end. The elongated expandable member can include a gelatin material or a collagen material that is configured, when wetted, to expand from a compressed first diametrical size to a second larger diametrical size within a time period of 5 minutes or less. At the second larger diametrical size, the gelatin or collagen material can occlude a vascular vessel for a period of at least 20 days without degrading.

摘要翻译： 公开了用于闭塞血管的静脉曲张，套件和方法，例如静脉曲张。 组件可以包括可拆卸的内部构件，可移除的外部构件和在内部构件和外部构件的部分之间以压缩形式定位的细长可扩展构件。 为了便于其移除，内部和外部构件中的一个或两个可以包括联接到近端的手柄。 细长可扩张构件可以包括明胶材料或胶原材料，其在被润湿时被构造成在5分钟或更短的时间段内从压缩的第一直径尺寸膨胀到第二较大直径尺寸。 在第二个更大的直径尺寸下，明胶或胶原材料可以将血管容器封闭至少20天的时间，而不会降解。

公开(公告)号：US08758427B2

公开(公告)日：2014-06-24

申请号：US13310503

申请日：2011-12-02

申请人： Howard Root ,  James Murto ,  Stephen Penegor ,  Gregg Sutton

发明人： Howard Root ,  James Murto ,  Stephen Penegor ,  Gregg Sutton

IPC分类号： A61F2/06

CPC分类号： A61B17/12109 ,  A61B17/12031 ,  A61B17/1219 ,  A61B2017/00429 ,  A61B2017/00526 ,  A61B2017/00889 ,  A61B2017/00893 ,  A61B2017/00898 ,  A61B2017/00942 ,  A61B2017/1205 ,  A61B2017/12054 ,  A61L31/044 ,  A61L31/045 ,  A61L31/146 ,  A61L31/16 ,  A61L2300/404 ,  A61L2430/36 ,  F04C2270/041

摘要： Assemblies, kits, and methods for occluding a vascular vessel, such as a varicose vein, are disclosed. An assembly can include a removable inner member, a removable outer member, and an elongated expandable member positioned in a compressed form between portions of the inner and outer members. To facilitate their removal, one or both of the inner and outer members can include a handle coupled to a proximal end. The elongated expandable member can include a gelatin material or a collagen material that is configured, when wetted, to expand from a compressed first diametrical size to a second larger diametrical size within a time period of 5 minutes or less. At the second larger diametrical size, the gelatin or collagen material can occlude a vascular vessel for a period of at least 20 days without degrading.

摘要翻译： 公开了用于闭塞血管的静脉曲张，套件和方法，例如静脉曲张。 组件可以包括可拆卸的内部构件，可移除的外部构件和在内部构件和外部构件的部分之间以压缩形式定位的细长可扩展构件。 为了便于其移除，内部和外部构件中的一个或两个可以包括联接到近端的手柄。 细长可扩张构件可以包括明胶材料或胶原材料，其在被润湿时被构造成在5分钟或更短的时间段内从压缩的第一直径尺寸膨胀到第二较大直径尺寸。 在第二个更大的直径尺寸下，明胶或胶原材料可以将血管容器封闭至少20天的时间，而不会降解。