公开(公告)号：US4497929A

公开(公告)日：1985-02-05

申请号：US399404

申请日：1982-07-19

申请人： James W. Brown ,  Tsang J. Chen ,  Michael A. Schen

发明人： James W. Brown ,  Tsang J. Chen ,  Michael A. Schen

IPC分类号： C08F20/28 ,  C08F20/58 ,  G03C1/053 ,  G03C1/835 ,  G03C7/388 ,  C08L41/00 ,  C08L43/00

CPC分类号： G03C1/053 ,  C08F20/28 ,  C08F20/58 ,  G03C1/835 ,  G03C7/3882

摘要： A latex composition having utility in articles such as photographic elements is disclosed. The composition comprises loadable polymer particles having recurring units a, b and c wherein:component a is 10 to 100 weight percent of a tetrahydrofurfuryl monomer having the structure: ##STR1## in which R.sub.1 represents O or NH; andR.sub.2 represents H or lower alkyl of about 1 to 6 carbon atoms;component b is 0 to 20 weight percent of a hydrophilic monomer andcomponent c is 0 to 90 weight percent of a hydrophobic monomer.

公开(公告)号：US4684608A

公开(公告)日：1987-08-04

申请号：US800197

申请日：1985-11-21

申请人： James W. Brown ,  Tsang J. Chen ,  Michael A. Schen

发明人： James W. Brown ,  Tsang J. Chen ,  Michael A. Schen

IPC分类号： C08F20/28 ,  C08F20/58 ,  G03C1/04 ,  G03C1/835 ,  G03C7/388 ,  G03C1/02

CPC分类号： G03C1/835 ,  C08F20/28 ,  C08F20/58 ,  G03C1/04 ,  G03C7/3882

摘要： A latex composition having utility in articles such as photographic elements is disclosed. The composition comprises loadable polymer particles having recurring units a, b and c wherein:component a is 10 to 100 weight percent of a tetrahydrofurfuryl monomer having the structure: ##STR1## in which R.sub.1 represents O or NH; andR.sub.2 represents H or lower alkyl of about 1 to 6 carbon atoms;component b is 0 to 20 weight percent of a hydrophilic monomer andcomponent c is 0 to 90 weight percent of a hydrophobic monomer.

摘要翻译： 公开了一种在诸如照相元件的物品中具有效用的胶乳组合物。 组合物包含具有重复单元a，b和c的可负载聚合物颗粒，其中：组分a为10至100重量％的具有以下结构的四氢糠基单体：其中R 1表示O或NH; 并且R 2表示H或具有约1至6个碳原子的低级烷基; 组分b是0至20重量％的亲水性单体，组分c为0至90重量％的疏水单体。

公开(公告)号：US4608424A

公开(公告)日：1986-08-26

申请号：US660157

申请日：1984-10-12

申请人： James W. Brown ,  Tsang J. Chen ,  Michael A. Schen

发明人： James W. Brown ,  Tsang J. Chen ,  Michael A. Schen

IPC分类号： C08F20/28 ,  C08F20/58 ,  G03C1/04 ,  G03C1/835 ,  G03C7/388 ,  C08F30/04

CPC分类号： C08F20/58 ,  C08F20/28 ,  G03C1/04 ,  G03C1/835 ,  G03C7/3882

摘要： A latex composition having utility in articles such as photographic elements is disclosed. The composition comprises loadable polymer particles having recurring units a, b and c wherein:component a is 10 to 100 weight percent of a tetrahydrofurfuryl monomer having the structure: ##STR1## in which R.sub.1 represents O or NH; andR.sub.2 represents H or lower alkyl of about 1 to 6 carbon atoms;component b is 0 to 20 weight percent of a hydrophilic monomer andcomponent c is 0 to 90 weight percent of a hydrophobic monomer.

公开(公告)号：US4735907A

公开(公告)日：1988-04-05

申请号：US713202

申请日：1985-03-18

申请人： James R. Schaeffer ,  Tsang J. Chen ,  Michael A. Schen

发明人： James R. Schaeffer ,  Tsang J. Chen ,  Michael A. Schen

IPC分类号： G01N21/76 ,  C08F8/00 ,  C08G81/00 ,  C08G81/02 ,  G01N33/533 ,  G01N33/543 ,  G01N33/545 ,  G01N33/58 ,  G01N33/546

CPC分类号： G01N33/585 ,  G01N33/533 ,  Y10S436/80 ,  Y10S436/805 ,  Y10S436/808 ,  Y10T428/2982

摘要： Improved fluorescent labels comprise a fluorescent rare earth chelate incorporated into a polymeric particle derived from a loadable latex. The polymer comprises: (a) from about 50 to about 96 weight percent of recurring units derived from a hydrophobic ethylenically unsaturated polymerizable monomer, (b) from about 2 to about 30 weight percent of recurring units derived from a nonionic hydrophilic ethylenically unsaturated polymerizable monomer, and (c) from about 2 to about 20 weight percent of recurring units derived from an anionic ethylenically unsaturated polymerizable monomer containing at least one solubilizing group. The labels of this invention have greatly improved stability in aqueous solutions and do not prematurely agglomerate during storage. They can be attached to any of a variety of physiologically reactive species to provide labeled species, and are particularly useful in specific binding assays.

摘要翻译： 改进的荧光标记包括掺入衍生自可加载胶乳的聚合物颗粒中的荧光稀土螯合物。 聚合物包含：（a）约50至约96重量％的衍生自疏水性烯属不饱和可聚合单体的重复单元，（b）约2至约30重量％的衍生自非离子亲水烯属不饱和可聚合单体的重复单元 ，和（c）约2-约20重量％的衍生自含有至少一个增溶基团的阴离子烯属不饱和可聚合单体的重复单元。 本发明的标签大大提高了水溶液的稳定性，并且在储存期间不会过早聚集。 它们可以连接到各种生理反应性物质中的任一种以提供标记的物质，并且在特异性结合测定中特别有用。

公开(公告)号：US4784912A

公开(公告)日：1988-11-15

申请号：US112302

申请日：1987-10-26

申请人： James R. Schaeffer ,  Tsang J. Chen ,  Michael A. Schen

发明人： James R. Schaeffer ,  Tsang J. Chen ,  Michael A. Schen

IPC分类号： G01N21/76 ,  C08F8/00 ,  C08G81/00 ,  C08G81/02 ,  G01N33/533 ,  G01N33/543 ,  G01N33/545 ,  G01N33/58 ,  B32B27/32 ,  G01N33/546

CPC分类号： G01N33/585 ,  G01N33/533 ,  Y10S436/80 ,  Y10S436/805 ,  Y10S436/808 ,  Y10T428/2982

摘要： Improved fluorescent labels comprise a fluorescent rare earth chelate incorporated into a polymeric particle derived from a loadable latex. The polymer comprises: (a) from about 50 to about 96 weight percent of recurring units derived from a hydrophobic ethylenically unsaturated polymerizable monomer, (b) from about 2 to about 30 weight percent of recurring units derived from a nonionic hydrophilic ethylenically unsaturated polymerizable monomer, and (c) from about 2 to about 20 weight percent of recurring units derived from an anionic ethylenically unsaturated polymerizable monomer containing at least one solubilizing group. The labels of this invention have greatly improved stability in aqueous solutions and do not prematurely agglomerate during storage. They can be attached to any of a variety of physiologically reactive species to provide labeled species, and are particularly useful in specific binding assays.

摘要翻译： 改进的荧光标记包括掺入衍生自可加载胶乳的聚合物颗粒中的荧光稀土螯合物。 聚合物包含：（a）约50至约96重量％的衍生自疏水性烯属不饱和可聚合单体的重复单元，（b）约2至约30重量％的衍生自非离子亲水烯属不饱和可聚合单体的重复单元 ，和（c）约2-约20重量％的衍生自含有至少一个增溶基团的阴离子烯属不饱和可聚合单体的重复单元。 本发明的标签大大提高了水溶液的稳定性，并且在储存期间不会过早聚集。 它们可以连接到各种生理反应性物质中的任一种以提供标记的物质，并且在特异性结合测定中特别有用。